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| 1 | 大功率离子推力器和流动控制单元验证现状及其2000小时寿命试验(英文)显示文摘为了发展基于电推进的大功率空间运输系统,需要开发和验证功率达数十千瓦的电推进系统,深空任务电推进系统优化的比冲要求高达105s。凯尔迪什研究中心(KeRC)正在开发这样的电推进部件。本文概述了35kW离子推力器IT-500及其流动单元FCU-500的验证现状。作为其验证的一部分,完成了IT-500和FCU-500的2000h寿命试验。其中,离子推力器大部分验证条件是:输入功率17.8kW,使用了40kg氙,2018h寿命试验。本文介绍了磁场和离子光学以及石墨格栅开发现状。 | Alexander S Lovtsov Michael Y Selivanov Andrey N Kostin Andrey A Shagayda | 2020 | 推进技术2020，41，1： | 2 |
| 2 | Strategies to tackle the challenges of external beam radiotherapy for liver tumors显示文摘Primary and metastatic liver cancer is an increasingly common and difficult to control disease entity.Radiation offers a non-invasive treatment alternative for these patients who often have few options and a poor prognosis.However,the anatomy and aggressiveness of liver cancer poses significant challenges such as accurate localization at simulation and treatment,management of motion and appropriate selection of dose regimen.This article aims to review the options available and provide information for the practical implementation and/or improvement of liver cancer radiation programs within the context of stereotactic body radiotherapy and image-guided radiotherapy guidelines.Specific patient inclusion and exclusion criteria are presented given the significant toxicity found in certain sub-populations treated with radiation.Indeed,certain sub-populations,such as those with tumor thrombosis or those with larger lesions treated with transarterial chemoembolization,have been shown to have significant improvements in outcome with the addition of radiation and merit special consideration.Implementing a liver radiation programrequires three primary challenges to be addressed:(1) immobilization and motion management;(2) localization;and(3) dose regimen and constraint selection.Strategies to deal with motion include simple internal target volume(ITV) expansions,non-gated ITV reduction strategies,breath hold methods,and surrogate marker methods to enable gating or tracking.Localization of the tumor and organs-at-risk are addressed using contrast infusion techniques to take advantage of different normal liver and cancer vascular anatomy,imaging modalities,and margin management.Finally,a dose response has been demonstrated and dose regimens appear to be converging.A more uniform approach to treatment in terms of technique,dose selection and patient selection will allow us to study liver radiation in larger and,hopefully,multicenter randomized studies. | Michael I Lock Jonathan Klein Hans T Chung Joseph M Herman Edward Y Kim William Small Nina A Mayr Simon S Lo | 2017 | World Journal of Hepatology2017，9，14： | 2 |
| 3 | A positive feedback loop between the p53 and Lats2 tumor suppressors pre- vents tetraploidization显示文摘 | Aylon Y Michael D Shmueli A | 2006 | Genes Dev2006，20，19： | 1 |
| 4 | Quasi-optical and spatial power combining显示文摘 | MICHAEL P D ROBERT A Y | 2002 | IEEE Transactions on Microwave Theory and Techniques2002，50，3： | 1 |
| 5 | Adjacent segment disease : an uncommon complication after cervical expansile laminoplasty : case re- port显示文摘 | Michael Y Barth A Elizabeth V | 2003 | Neurosurgery2003，53，： | 1 |
| 6 | Renal outcomes with different fixed-dose combination therapies in patients with hypertension at high risk for cardiovascular events (ACCOMPLISH): a prespecified secondary analysis of a randomised controlled trial显示文摘 | George L Bakris Pantelis A Sarafidis Matthew R Weir Bj?rn Dahl?f Bertram Pitt Kenneth Jamerson Eric J Velazquez Linda Staikos-Byrne Roxzana Y Kelly Victor Shi Yann-Tong Chiang Michael A Weber | 2010 | The Lancet2010，，9721： | 1 |
| 7 | Codon-54 polymorphism of the fatty acid-binding protein 2 gene is associated with elevation of fasting and postprandial triglyceride in type 2 diabetes显示文摘 | Angeliki G Omer A Michael Y | 2000 | J Clin Endocrinol Metab2000，85，9： | 1 |
| 8 | Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice显示文摘 | Usher Michael G Duan Sheng Zhong Ivaschenko Christine Y Frieler Ryan A Berger Stefan Schütz Günther Lumeng Carey N Mortensen Richard M | 2010 | Journal of Clinical Investigation2010，，9： | 1 |
| 9 | Detection of mitochondria derived reactive oxygen species production by the chemilumigenic probes lucigenin and luminol 显示文摘 | LI Y B ZHU H MICHAEL A | 1999 | Biochimica et Biophysica Acta1999，1428，： | 1 |
| 10 | Arsenic migration to deep groundwater in Bangladesh influenced by adsorption and water demand显示文摘 | Radloff K A Zheng Y Michael H A | | 0，，04： | 1 |
| 11 | Characterization of a cDNA encoding a novel heat- shock protein that binds to calmodulin显示文摘 | Nihal dharmasiri M A Michael Harrington H | 1995 | Plant Physiol1995，108，： | 1 |
| 12 | Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts显示文摘 | Michael A L Kent Y C | 2007 | Nature Biotechnology2007，25，： | 1 |
| 13 | The draft genome of the transgenic tropical fruit tree papaya ( Carica pap aya Linnaeus ) 显示文摘 | MING R HOU S B FENG Y YU Q DIONNE-LAPORTE A SAW J H SENIN P WANG W LY B V LEWIS K L T SALZBERG S L FENG L GONES M R SKELTON R L MURRAYJ E CHEN C QIAN W SHEN J DU P EUSTICE M TONG E TANG H LYONS E PAULL R E MICHAEL T P WALL K RICE D W ALBERT H WANG M L ZHU Y J SCHATZ M NAGARAJAN N ACOB R A GUAN P BLAS A WAI C M ACKERMAN C M REN Y LIU C WANG J M WANG J P NA J SHAKIROV E V HAAS B THIMMAPURAM J NELSON D WANG X BOWERS J E GSCHWEND A R DELCHER A L SINGH R SUZUKI J Y TRIPATHI S NEUPANE K WEI H IRIKURA B PAIDI M JIANG N ZHANG W PRESTING G WINDSOR A NAVAJAS-PEREZ R TORRES M J FELTUS A PORTER B LI Y BURROUGHS A M LUO M C LIU L CHRISTOPHER D A MOUNT S M MOORE P H SUGIMURA T JIANG J SCHULER M A FRIEDMAN V MITCHELL-OLDS T SHIPPEN D E PAMPHILIS C W PALMER J D FREELING M PATERSON A H GONSALVES D WANG L ALAM M | 2008 | Nature2008，452，： | 1 |
| 14 | Longitudinal trends in the association of metabolic syndrome with 550 k single nueleotide polymorphisms in the Framingbam Hearl Study显示文摘 | YONG-MOON P MICHAEL A P GAO X Y | 2009 | BMC Proceed- ings2009，3，7： | 1 |
| 15 | Open door cervical expansile laminoplasty显示文摘 | MICHAEL Y WANG M D BARTH A | 2004 | Neurosurgery2004，54，1： | 1 |
| 16 | Junction metrology by cross-sectional atomic force microscopy显示文摘 | ROGER A BRYANT M MICHAEL Y | 1996 | J Vae Sci Tehnol B1996，14，1： | 1 |
| 17 | Polymorphisms in the fatty acid-binding protein 2 and apolipoprotein C-Ⅲ genes are associated with the metabolic syndrome and dyslipidemia in a south indian population显示文摘 | Guttier J Georgopoulos A Michael Y | 2005 | J Clin Endocrinol Metab2005，90，3： | 1 |
| 18 | Direct bandpass sampling of multiple distinct RF signals显示文摘 | DENNIS A M MICHAEL S JAMES B Y | 1999 | IEEE transactions on communications1999，47，7： | 1 |
| 19 | An estimation method for the semiparametric mixed effects model显示文摘 | TAO H BRIAN S Y MICHAEL A N | 1999 | Biometrics1999，55，1： | 1 |
| 20 | Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways显示文摘 | Michael A Crackower Gavin Y | 2002 | Cell2002，110，6： | 1 |
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