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| 1 | Effect of moxa-burning heat stimulating Liangmen(ST 21) and Zusanli(ST 36) on proliferation and apoptosis signaling proteins in rats with stress-induced gastric ulcer显示文摘OBJECTIVE: To observe the effect of moxa-burning heat stimulating acupoints of Liangmen(ST 21)and Zusanli(ST 36) on the proliferation and apoptosis signaling proteins in rats with stress-induced gastric ulcer.METHODS: Forty rats were randomly divided into four groups: negative control(NC), ulcer control(UC), acupoints of stomach meridian(ASM), and acupoints control(AC). The acute gastric ulcer model was established by bound and water immersion.Rats in NC and UC groups didn't receive any moxa-burning heat stimulating treatment, while rats in ASM and AC groups were treated with buringmoxa heat stimulating the acupoints of Liangmen(ST 21) and Zusanli(ST 36) and their controlled points, respectively. Rats in all groups were sacrificed after 12 consecutive days treatment. The ulcer index was evaluated by using Guth's method.The expression of tumor necrosis factor-alpha(TNF-α), apoptotic protease activating facter-1(Apaf-1), Caspase-3, p21 activated kinase 1(PAK1),extracellular regulated protein kinases 2(ERK2),phosphorylated ERK2(p ERK2), phosphoinositide3-kinase(PI3K) and RAC-alpha serine/threonine-protein kinase(Akt) in gastric mucosa was detected by enzyme linked immunosorbent assay(ELISA).RESULTS: Compared with UC group, the ulcer index of ASM and AC groups decreased, and the injured gastric mucosa was improved, the expression of TNF-α, Apaf-1 and Caspase-3 in gastric mucosa was significantly reduced(P < 0.05), while the ex-pression of PAK1, ERK2, p ERK2, PI3 K and Akt in gastric mucosa was significantly increased(P < 0.05).And ASM showed better effect than AC group(P <0.05).CONCLUSION: Moxa-burning Heat stimulating of Liangmen(ST 21) and Zusanli(ST 36) could promote the recovery of gastric mucosal lesion probably by inhibiting cell apoptosis and promoting cell proliferation in stress-induced gastric ulcer. | Peng Li Wang Yadong Chang Xiaorong Wu Huangan Liu Mi Ma Fuqiang Wang Hong Chen Jiaolong Wang Chao Quan Renfu Yang Zongbao | 2016 | Journal of Traditional Chinese Medicine2016，36，3： | 9 |
| 2 | Triglycerides and ratio of triglycerides to high-density lipoprotein cholesterol are better than liver enzymes to identify insulin resistance in urban middle-aged and older non-obese Chinese without diabetes显示文摘 | Sun Yu Li Wenjuan Hou Xinguo Wang Chuan Li Chengqiao Zhang Xiuping Yang Weifang Ma Zeqiang Wang Weiqing Ning Guang Zheng Huizhen Ma Aixia Song Jun Lin Peng Liang Kai Liu Fuqiang Gong Lei Wang Meijian Xiao Juan Yan Fei Yang Junpeng Wang Lingshu Tian Meng Liu Jidong Zhao Ruxing Zhu Ping Chen Li | 2014 | Chinese Medical Journal2014，，10： | 7 |
| 3 | Epidemiological serosurvey of Hepatitis B in China—Declining HBV prevalence due to Hepatitis B vaccination显示文摘 | Xiaofeng Liang Shengli Bi Weizhong Yang Longde Wang Gang Cui Fuqiang Cui Yong Zhang Jianhua Liu Xiaohong Gong Yuansheng Chen Fuzhen Wang Hui Zheng Feng Wang Jing Guo Zhiyuan Jia Jingchen Ma Huaqing Wang Huiming Luo Li Li Shuigao Jin Stephen C. Hadler Yu W | 2009 | Vaccine2009，，47： | 7 |
| 4 | SOD1^(G93A) Induces a Unique PSAP-Dependent Mitochondrial Apoptosis Pathway via Bax-Bak Interaction显示文摘Amyotrophic lateral syndrome(ALS)is a progressive degenerative disorder characterized by motor neuron death and axon degeneration.Mitochondrial dysfunction plays a key role in the pathogenesis of ALS,the mechanism of which remains poorly understood.The B-cell lymphoma-2(Bcl-2)family of proteins that control and mediate mitochondrial function and apoptosis,including the pro-apoptotic members Bcl2-Associated X(Bax),are involved in ALS development.The death receptor 6(DR6)regulates motor neuron death in ALS,and DR6 antibodies can prevent axon degeneration and motor neuron damage by blocking DR6.Previous studies demonstrated that PSAP localized to mitochondria and was required for DR6-induced apoptosis.In this study,SOD1^(G93A) was transfected into the motor neuron cell line NSC-34 to serve as an ALS cell model in vitro.The data assessed the role of PSAP in SOD1^(G93A)induced apoptosis and demonstrated that the overexpression of SOD1^(G93A),but not wtSOD1,induced PARP cleavage,caspase-3 activation,cytochrome c release,and Bax translocation.PSAP,Bax,and Bak were necessary for SOD1^(G93A)induced apoptosis,as silencing PSAP inhibited SOD1^(G93A)-mediated cell death that was dependent on Bax-Bak interaction. | HAN NIU XIN CHEN XUEQI FU JINGTIAN ZHANG GUODONG LI YUXIANG WANG JIAYUE SONG XUETING MA CHEN HU XUEMIN XU FUQIANG ZHANG LINLIN ZENG | 2021 | BIOCELL2021，45，4： | 2 |
| 5 | Anexperimental study on the atomization characteristics ofimpinging jets of power law fluid显示文摘 | Ma Yongcui Bai Fuqiang Chang Qing | 2015 | Journal of Non-Newtonian Fluid Mechanics2015，217，： | 1 |
| 6 | Constant stress ADT for superluminescent diode and statistical analysis显示文摘 | LI Xiaoyang JIANG Tongmin SUN Fuqiang MA Jing | | 0，，02： | 1 |
| 7 | Dike Breach Risks of Different Flood Conditions in the Lower Yellow River显示文摘Based on the analysis of hanging rivers' actuality in the lower Yellow River and researches related to the evaluation of dike breach risks,it is put forward that the influencing factors of dike beach risks in the lower Yellow River should involve four aspects,the flow and sediment movement,the regional crustal stability,the variation of river regime and the stability of river dikes.With this,the evaluation indexes system of dike breach risks is established,and with the support of geographic information systems technology,the model of multi-hierarchical fuzzy comprehensive judgment is applied to estimate the dike beach risks of the hanging rivers in the lower Yellow River under different flood conditions.The evaluation results of dike breach risks show the following distributing regularities of dike breach risks in the lower Yellow River:(1) Dike breach risks increase with the increase of the flood.(2) Dike breach risks decrease with the changes of river patterns along the channel.(3) There are great risks of dike breach in the wandering reaches,and it is relatively higher in the south bank than in the north in wandering reaches.(4) There is a higher dike breach risk in the north bank than in the south in winding reaches.Simultaneously,the evaluation results manifest that the evaluation indexes system established from the flow and sediment movement,the regional crustal stability,the variation of river regime and the stability of river dikes can represent the actual situation of the lower Yellow River more comprehensively.The application of multihierarchical fuzzy comprehensive judgment can preferably resolve the problem of hanging river dike breach,which has numerous influencing factors and complicated functionary mechanisms.The applications of geographic information systems technology with powerful spatial analysis functions make dike beach risks quantificationally displayed in different spatial positions,and reflect the differences of dike beach risks in different spatial positions of the channel in the lower Yellow River. | Xia Fuqiang Wu Shaohong Yang Qinye Kang Xiangwu Ma Xin | 2010 | Chinese Journal of Population,Resources and Environment2010，8，1： | 1 |
| 8 | Epidemiological serosurvey of Hepatitis B in China—Declining HBV prevalence due to Hepatitis B vaccination显示文摘 | Xiaofeng Liang Shengli Bi Weizhong Yang Longde Wang Gang Cui Fuqiang Cui Yong Zhang Jianhua Liu Xiaohong Gong Yuansheng Chen Fuzhen Wang Hui Zheng Feng Wang Jing Guo Zhiyuan Jia Jingchen Ma Huaqing Wang Huiming Luo Li Li Shuigao Jin Stephen C. Hadler Yu W | 2009 | Vaccine2009，，47： | 1 |
| 9 | Constant stress ADT for superluminescent diode and statistical analysis显示文摘 | LI Xiaoyang JIANG Tongmin SUN Fuqiang MA Jing | 2010 | Maintenance and Reliability2010，46，2： | 1 |
| 10 | Epidemiological serosurvey of Hepatitis B in China—Declining HBV prevalence due to Hepatitis B vaccination显示文摘 | Xiaofeng Liang Shengli Bi Weizhong Yang Longde Wang Gang Cui Fuqiang Cui Yong Zhang Jianhua Liu Xiaohong Gong Yuansheng Chen Fuzhen Wang Hui Zheng Feng Wang Jing Guo Zhiyuan Jia Jingchen Ma Huaqing Wang Huiming Luo Li Li Shuigao Jin Stephen C. Hadler Yu W | 2009 | Vaccine2009，，47： | 1 |
| 11 | Epidemiological serosurvey of Hepatitis B in China—Declining HBV prevalence due to Hepatitis B vaccination显示文摘 | Xiaofeng Liang Shengli Bi Weizhong Yang Longde Wang Gang Cui Fuqiang Cui Yong Zhang Jianhua Liu Xiaohong Gong Yuansheng Chen Fuzhen Wang Hui Zheng Feng Wang Jing Guo Zhiyuan Jia Jingchen Ma Huaqing Wang Huiming Luo Li Li Shuigao Jin Stephen C. Hadler Yu W | 2009 | Vaccine2009，，47： | 1 |
| 12 | Evaluation of crustal stability in the lower Yellow River region显示文摘 | YANG Qinye MA Xin LI Zhizhong XIA Fuqiang | 2006 | Chinese Science Bulletin2006，51，B11： | 1 |
| 13 | Epidemiological serosurvey of Hepatitis B in China—Declining HBV prevalence due to Hepatitis B vaccination显示文摘 | Xiaofeng Liang Shengli Bi Weizhong Yang Longde Wang Gang Cui Fuqiang Cui Yong Zhang Jianhua Liu Xiaohong Gong Yuansheng Chen Fuzhen Wang Hui Zheng Feng Wang Jing Guo Zhiyuan Jia Jingchen Ma Huaqing Wang Huiming Luo Li Li Shuigao Jin Stephen C. Hadler Yu W | 2009 | Vaccine2009，，47： | 1 |
| 14 | Analysis of Imaging Characteristics and Dynamic Changes of 3 Cases of Severe Novel Coronavirus Pneumonia in Qinghai Province显示文摘Objective:To analyze the characteristics,dynamic changes,and outcomes of the first imaging manifestations of 3 patients with severe COVID-19 in our hospital.Methods:Computed tomography(CT)findings of 3 patients with severe COVID-19 who tested positive by the nucleic acid test in our hospital were selected,mainly focusing on the morphology,distribution characteristics,and dynamic changes of the first CT findings.Results:3 patients with severe pneumonia were older,with one aged 80.The first chest CT examination for all 3 patients differed.Imaging showed a leafy distribution of consolidation,primarily affecting the lower lobes of both lungs and extending subpleurally.A grid-like pattern was observed,along with changes in the consolidation and air bronchogram.These changes had slower absorption,especially in patients with underlying diseases.Conclusion:CT manifestations of severe COVID-19 have specific characteristics and the analysis of their characteristics and dynamic changes provide valuable insights for clinical treatment. | Yingfang Yu Ruiyun Zhao Changde Li Fuqiang Ma Lingyun Guo Yang Li | 2024 | Journal of Clinical and Nursing Research2024，8，3： | 0 |
| 15 | The characteristics of dike-break flood in different scenarios of the lower Yellow River based on numerical simulations显示文摘更低的黄河仍然由于全球环境变化,河隧道沉积,在堤的隐藏的危险和鈥渉a nging 河鈥的相反的河政体引起的不平常的降水面对洪水的威胁吗?根据黄河的堤裂缝洪水的特征,这份报纸模仿了,在到二维的不稳定的流动模型的六种不同情形,由输入地面数据的堤裂缝洪水路由,典型历史的洪水数据和学习区域的陆地使用数据。结果显示出那:第一,洪水的路由进程将在到达更低的活动范围以后在到河的路和回来上占据另外的河;在一样的河活动范围,第二泛滥淹没北方乐队的区域在在一样的历史的洪水下面的南岸的相应地点比那大;第三,它由于在洪水平原的不同地理地点在在不同区域的洪水淹没的度是不同的;第四,洪水是深的主流的区域和流动速度是快的相对更小,但是区域非主流在洪水是浅的,流动速度是慢的的地方,相对大;并且最后,堤裂缝洪水的可能的影响区域是 141,948 km2。 | MA Xin YANG Peiguo YANG Qinye KANG Xiangwu XIA Fuqiang | 2007 | Journal of Geographical Sciences2007，17，1： | 0 |
| 16 | Energy estimation and coupling synchronization between biophysical neurons显示文摘Static charges can induce spatial electric field while moving charges can induce magnetic field.As a result,continuous pumping and exchange of intercellular and extracellular Calcium,potassium and sodium of cells will generate time-varying magnetic field in the media.Therefore,the physical effect of electromagnetic induction in neural activities should be included in building biological neurons.On the other hand,the occurrence of action potential and propagation of ions require energy consumption and supply,so the estimation of physical energy becomes important.Based on our memristive biophysical neuron model,the Hamilton energy function is obtained by using the Helmholtz’s theorem,and this energy is contributed by the electric field and magnetic field described by magnetic flux.It is found that this improved neuron model can present the main dynamical properties in neural activities,and it characterizes the lower threshold behavior and subthreshold oscillation during refractory period.The external forcing current on an isolate is adjusted to calculate the firing patterns,energy function and mode transition,which shows the dependence of energy on electrical activities.Finally,magnetic coupling is triggered to modulate the phase synchronization between two identical neurons connected by electric synapse,respectively. | WU FuQiang MA Jun ZHANG Ge | 2020 | Science China(Technological Sciences)2020，63，4： | 0 |
| 17 | Synergy of first-and second-sphere interactions in a covalent organic framework boosts highly selective platinum uptake显示文摘Platinum recovery from waste electrical and electronic equipment(WEEE) in highly acidic solutions is significant to the electronics industry and environmental remediation. However, the lack of ingenious design and synergetic coordination gives rise to unsatisfied PtCl_(4)^(2-)extraction capacities and selectivities in most previously reported adsorbents(e.g., polymeric and inorganic materials). Herein, we proposed a synergistic strategy that realizes highly selective PtCl_(4)^(2-)uptake through first-and second-sphere coordinations. The proof-of-concept imine-linked covalent organic framework(SCU-COF-3) was found to chelate Pt Cl42-via the direct N…Pt coordination and the synergistically interlaminar N–H…Cl hydrogen bonds, which was disclosed by the comprehensive analysis of extended X-ray adsorption fine structure(EXAFS) characterizations and density functional theory(DFT) calculations. The unique adsorption mechanism imparts a superior adsorption capacity(168.4 mg g-1)and extraordinary Pt(II) selectivity to SCU-COF-3 under static conditions. In addition, SCU-COF-3 exhibits an upgraded distribution coefficient of 1.62 × 10^(5)mL· g^(-1), one order of magnitude higher than those of reported natural adsorbents. Specifically, SCU-COF-3 can extract PtCl_(4)^(2- )quantitatively from a simulated acidic waste solution coexisting with other 12 competitive ions, suggesting its promising application in practical scenarios. | Linwei He Baoyu Li Zhonglin Ma Lixi Chen Shicheng Gong Mingxing Zhang Yaoyao Bai Qi Guo Fuqi Wu Fuqiang Zhao Jie Li Duo Zhang Daopeng Sheng Xing Dai Long Chen Jie Shu Zhifang Chai Shuao Wang | 2023 | Science China Chemistry2023，66，3： | 0 |
| 18 | In situ annealing effects on magnetic properties and variable-range hopping of iron-based ladder material BaFe2S3显示文摘All iron-based superconductors,regardless of their detailed crystal structure,share the same conductive Fe_2X_2(X=As,P,Se,and S)layers as the crucial structural unit[1-8].In the Fe_2X_2 layers,edge-shared FeX_4 tetrahedra form a square lattice in quasi-two-dimensional(quasi-2D)planes.One may wonder what kind of properties will be manifested in the quasi-one-dimensional(quasi-1D)counterparts exhibiting an identical coordination as the above-mentioned | Xuan Zhang Hui Zhang YongHui Ma LingLing Wang JiaNan Chu Tao Hu Gang Mu YuMing Lu ChuanBing Cai FuQiang Huang XiaoMing Xie | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，7： | 0 |
| 19 | Flow Characteristics of Large-Scale Liquefaction-Slip of the Loess Strata in Shibei Tableland, Guyuan City,Induced by the 1920 Haiyuan M81/2 Earthquake显示文摘Based on the dynamic triaxial liquefaction test of the loess samples which are taken from Shibei tableland,Guyuan City,Ningxia,China,the characteristics of dynamic strain,dynamic stress and pore water pressure are studied under cyclic loading.Triaxial shear test is conducted immediately after the sample reaches liquefaction point.During the test,the property of the liquefied soil is analyzed through fluid mechanics method,whereby the fluidity of the liquefied soil is represented by apparent viscosity.The results show that the fluidity of liquefied loess changes from“shear thickening”to“shear thinning”as the shear force continues,and the fluidity of liquefied loess is closely related to its structure.In addition,in the process of forming a new stable state,the apparent viscosity and deviant stress change with axial strain in a similar approach.When the sample reaches its stable state,it meanwhile shows a relatively stable apparent viscosity.According to the fluid mechanics and the law of conservation of energy,the slip distance of the liquefied soil is estimated,and the results are in good agreement with the field investigation results. | MA Xingyu WANG Lanmin WANG Qian WANG Ping ZHONG Xiumei PU Xiaowu LIU Fuqiang XU Xiaowei | 2020 | Earthquake Research in China2020，34，4： | 0 |
| 20 | Observation of room‐temperature out‐of‐plane switchable electric polarization in supported 3R‐MoS_(2) monolayers显示文摘Two‐dimensional(2D)ferroelectrics have attracted considerable attention due to their potential in the development of devices of miniaturization and multifunction.Although several van der Waals(vdW)‐layered materials show ferroelectricity,the experimental demonstrations of ferroelectric behavior in monolayers are very limited.Here we report the observation of room‐temperature out‐of‐plane switchable electric polarization in supported MoS_(2) monolayers exfoliated from 3R‐stacked bulk crystals under ambient conditions.Using in situ piezoelectric force microscopy and Kelvin probe force microscopy in a glovebox,we reveal that trapped water/ice molecules are responsible for this switchable electric polarization and this conclusion is strongly supported by theoretical simulations.It is worth noting that the water/ice trapping in the monolayers exfoliated from 2H‐stacked MoS_(2) crystals is not as much as that in 3R monolayers and,consequently,the out‐of‐plane electric polarization is missing there.Our findings indicate that monolayers with a trapped single layer of polar molecules might be emerging alternatives to 2D ferroelectrics.Furthermore,the stacking sequences may bring new properties and applications to 2D vdW materials not only when we stack them up but also when we thin them down. | Li Ma Liu Yang Yuqiang Fang Manzhang Xu Ruihuan Duan Vanessa Li Zhang Xuewen Wang Fuqiang Huang Menghao Wu Zheng Liu Ting Yu | 2023 | SmartMat2023，4，2： | 0 |
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