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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | Mechanosignaling activation of TGFβmaintains intervertebral disc homeostasis显示文摘Intervertebral disc(IVD) degeneration is the leading cause of disability with no disease-modifying treatment.IVD degeneration is associated with instable mechanical loading in the spine, but little is known about how mechanical stress regulates nucleus notochordal(NC) cells to maintain IVD homeostasis. Here we report that mechanical stress can result in excessive integrin α_vβ_6-mediated activation of transforming growth factor beta(TGFβ), decreased NC cell vacuoles, and increased matrix proteoglycan production, and results in degenerative disc disease(DDD). Knockout of TGFβ type II receptor(TβRII) or integrin α_v in the NC cells inhibited functional activity of postnatal NC cells and also resulted in DDD under mechanical loading.Administration of RGD peptide, TGFβ, and α_vβ_6-neutralizing antibodies attenuated IVD degeneration. Thus,integrin-mediated activation of TGFβ plays a critical role in mechanical signaling transduction to regulate IVD cell function and homeostasis. Manipulation of this signaling pathway may be a potential therapeutic target to modify DDD. | Qin Bian Lei Ma Amit Jain Janet L Crane Khaled Kebaish Mei Wan Zhengdong Zhang X Edward Guo Paul D Sponseller Cheryle A Seguin Lee H Riley Yongjun Wang Xu Cao | 2017 | Bone Research2017，5，1： | 9 |
| 3 | Variations in Wool Growth with Nutrient Supply in Northern China显示文摘Field studies on essessment of nutritional status of the grazing sheep were carried out in each of the three major grassland regions, the eastern Inner Mongolia and beyond grassland, the Inner Mongolia - Ningxia - Gansu grassland and the Xinjiang grassland, in northern China. The results obtained showed that the wool production of fine wool sheep in these regions varied between regions and seasons, with similar seasonal patterns in all regions and that reducing the seasonal variations in nutrient supply would enhance wool production substantially. Nutritional limitations to wool growth of the grazing sheep in these regions were suggested, those were: the shortage of protein supply in winter and early spring; the poor quality of much of the pasture and the hay used as supplements, the low energy intake during winter which probably necessitated the use of body stores to maintain body temperature. | D X Lu,Iner(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)Z C Feng,(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)H R Wang,(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)R Z Yang,(Xinjiang Institute of Animal Science.Xinjiang Academy of Animal Science.Yiu Hou Road.Urumqi.Xinjiang Uygur Autonomous Region PRC)C T Ma,(Chinese Academy of Agricultural Sciences.Lanzhou.Gansu.PRC)D B Purser,(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014)J R Lindsay(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014)D W Peter(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014) | 1997 | 畜牧与饲料科学1997，22，S1： | 3 |
| 4 | A Security-ConstrainedBid-ClearingSystem for the New Zealand Wholesale Elecrieity Market显示文摘 | Goodwin D Ma X | 1998 | IEEE Transactions on Power Systems1998，13，3： | 1 |
| 5 | Effect of Annealing Atmosphere on Magnetism for Fe-doped BaTiO3 Ceramic显示文摘 | Lin F T Jiang D M Ma X M | 2008 | Physica B2008，403，： | 1 |
| 6 | FTY720 demonstrates promising preclinical activity for chronic lymphocytic leukemia and lymphoblastic leukemia/lymphoma 显示文摘 | Liu Q Zhao X Frissom F Ma Y Santhanam R Jarjoura D | 2008 | Blood2008，，1： | 1 |
| 7 | Adult exposure to diethylstilbestrol induces spermatogenic cell apoptosis in vivo through increased oxidative stress in male hamster显示文摘 | Ma A Yang X Wang Z Shi D Chen Y | 2008 | Reprod Toxicol2008，25，3： | 1 |
| 8 | Study on the chemical constituents from the roots and stems of Sphaerophy sasalgula (Pall) DC显示文摘 | Ma Z J Meng D L Li X | 2003 | Plant Cell2003，20，2： | 1 |
| 9 | Detection and localization of rice stripe virus gene products in vivo显示文摘 | Liang D L Qu Z C Ma X Q | 2005 | Virus Genes2005，31，2： | 1 |
| 10 | Complete genome sequence of a novel flavivirus,duck Tembusu virus,isolated from ducks and geese in China显示文摘 | Yun T Zhang D Ma X | | 0，，06： | 1 |
| 11 | Heterotrimeric G proteins regulate nitrogen-use efficiency in rice 显示文摘 | Sun H Y Qian Q Wu K Luo J J Wang S S Zhang C W Ma Y F Liu Q Huang X Z Yuan Q B Han R X Zhao M Dong G J Guo L B Zhu X D Gou Z H Wang W Wu Y J Lin H X Fu X D | 2014 | Nature Genetics2014，46，4： | 1 |
| 12 | One dimensional CdS nanostructures= a prom ising candidate for optoelectronics 显示文摘 | Li H Wang X Xu J Zhang Q Bando Y Golberg D Ma Y Zhai T | 2013 | Advanced Mate- rials2013，25，22： | 1 |
| 13 | Fabrication of hollow and porous structured GdV04:Dy3+ nanospheres as anticancer drug carrier and MRI contrast agent显示文摘 | Kang X Yang D Ma P | 2013 | Langmuir2013，29，4： | 1 |
| 14 | The TIL commissioning and performance显示文摘 | X Zhang W Zheng X Wei F Jing Z Sui K Zheng Q Xu X Yuan X Jiang L Yang P Ma M Li J Wang D Hu S He F Li Z Peng B Feng H Zhou L Guo X Li X Zhang J Su Q Zhu H Yu R Zhao C Ma H He D Fan W Zhang | 2008 | Journal of Physics: Conference Series2008，，3： | 1 |
| 15 | Shape-selective isopropylation of naphthalene over mordenite catalysts: Computational analysis using MOPAC 显示文摘 | Ma X Schmitz A D | 1999 | Applied Catalysis A :General1999，182，1： | 1 |
| 16 | Congener specific distributions of polybrominated diphenyl ethers (PBDEs) in sediment and mussel (Mytilus edulis) of the Bo Sea, China 显示文摘 | WANG Z MA X D LIN Z S | 2009 | Chemusphere2009，74，7： | 1 |
| 17 | Parthenogenetic ac- tivation of mouse oocytes by strontium chloride: a search for the best conditions显示文摘 | Ma SF Liu X Y Miao D Q | 2005 | Theriogenology2005，64，： | 1 |
| 18 | Arsenic pollution ingroundwater from Hetao Area, China显示文摘 | Zhang H Ma S D Hu X | 2002 | Enviromnental Geology2002，41，： | 1 |
| 19 | Dysregulation of HSG triggers vascular proliferative disorders显示文摘 | CHEN K H GUO X M MA D | 2004 | Nature Cell Biol2004，6，9： | 1 |
| 20 | OFDM or single-carrier block transmissions显示文摘 | WANG Z D MA X L GIANNAKIS G B | 2004 | IEEE Transactions on Communications2004，52，3： | 1 |
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