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| 1 | Radiological response and inflammation scores predict tumour recurrence in patients treated with transarterial chemoembolization before liver transplantation显示文摘AIM To investigate the prognostic value of the radiological response after transarterial chemoembolization(TACE)and inflammatory markers in patients affected by hepatocellular carcinoma(HCC)awaiting liver transplantation(LT).METHODS We retrospectively evaluated the preoperative pre dictors of HCC recurrence in 70 patients treated with conventional(n=16)or doxorubicin-eluting bead TACE(n=54)before LT.The patient and tumour characteristics,including the static and dynamic alpha-fetoprotein,neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio( LR)measurements,were recorded.Treatment response was classified according to the modified Response Evaluation Criteria in Solid Tumours(m RECIST)and the European Association for the Study of the Liver(EASL)criteria as complete response(CR),partial response( R),stable disease o progressive disease.After examination of the explanted livers,histological necrosis was classified as complete(100%of the cumulative tumour area),partia(50%-99%)or minimal(<50%)and was correlated with the preoperative radiological findings.RESULTS According to the pre-TACE radiological evaluation,22/70(31.4%)and 12/70(17.1%)patients were beyond Milan and University of San Francisco(UCSF)criteria,respectively.After TACE procedures,the objective response(CR+ R)rates were 71.4%and 70.0%according to m RECIST and EASL criteria,respectively.The agreement between the two guidelines in defining the radiological response was rated as very good both for the overall and target lesion response(weighted k-value:0.98 and 0.93,respectively).Complete and partial histological necrosis were achieved in 14/70(20.0%)and 28/70(40.0%)patients,respectively.Using histopathology as the reference standard,m RECIST criteria correctly classified necrosis in 72.9%(51/70)of patients and EASL criteria in 68.6%(48/70)of cases.The m RECIST non-response to TACE[Exp(b)=9.2, =0.012],exceeding UCSF criteria before TACE[Exp(b)=4.7, =0.033]and a preoperative LR>150[Exp(b)=5.9, =0.046]were independent predictors of tumour recurrence.CONCLUSION The radiological response and inflammatory markers are predictive of tumour recurrence and allow the proper selection of TACE-treated candidates for LT. | Daniele Nicolini Andrea Agostini Roberto Montalti Federico Mocchegiani Cinzia Mincarelli Alessandra Mandolesi Nicola L Robertson Roberto Candelari Andrea Giovagnoni Marco Vivarelli | 2017 | World Journal of Gastroenterology2017，23，20： | 4 |
| 2 | Telomere-Specific Reverse Transcriptase (hTERT) and Cell-free RNA in Plasma as Predictors of Pathologic Tumor Response in Rectal Cancer Patients Receiving Neoadjuvant Chemoradiotherapy显示文摘 | Salvatore Pucciarelli Enrica Rampazzo Marta Briarava Isacco Maretto Marco Agostini Maura Digito Sonia Keppel Maria Friso Sara Lonardi Antonino Paoli Claudia Mescoli Donato Nitti Anita Rossi | 2012 | Annals of Surgical Oncology2012，，9： | 2 |
| 3 | Oxidative stress and apoptosis in immune diseases显示文摘 | Agostini M Di Marco B Nocentini G | 2002 | Int J Immunopathol2002，15，： | 1 |
| 4 | Multiplexed Protein Signal Pathway Mapping Identifies Patients With Rectal Cancer That Responds to Neoadjuvant Treatment显示文摘 | Enzo Mammano Francesca Galdi Mariaelena Pierobon Emanuela Tessari Jianghong Deng Salvatore Pucciarelli Marco Agostini Francesco De Marchi Vincenzo Canzonieri Antonino De Paoli Claudio Belluco Lance Liotta Emanuel Petricoin Pierluigi Pilati Donato Nitti | 2012 | Clinical Colorectal Cancer2012，，4： | 1 |
| 5 | Characteristics of Li 2 S 8 -tetraglyme catholyte in a semi-liquid lithium–sulfur battery显示文摘 | Marco Agostini Dong-Ju Lee Bruno Scrosati Yang Kook Sun Jusef Hassoun | 2014 | Journal of Power Sources2014，，： | 1 |
| 6 | Motion Artifact Reduction in Breast Dynamic Infrared Imaging显示文摘 | Valentina Agostini Marco Knaflitz | | 0，，03： | 1 |
| 7 | miRNAs in colon and rectal cancer: A consensus for their true clinical value显示文摘 | Marco Agostini Salvatore Pucciarelli Federica Calore Chiara Bedin MariaVittoria Enzo Donato Nitti | 2010 | Clinica Chimica Acta2010，，17： | 1 |
| 8 | Telomere-Specific Reverse Transcriptase (hTERT) and Cell-free RNA in Plasma as Predictors of Pathologic Tumor Response in Rectal Cancer Patients Receiving Neoadjuvant Chemoradiotherapy显示文摘 | Salvatore Pucciarelli Enrica Rampazzo Marta Briarava Isacco Maretto Marco Agostini Maura Digito Sonia Keppel Maria Friso Sara Lonardi Antonino Paoli Claudia Mescoli Donato Nitti Anita Rossi | 2012 | Annals of Surgical Oncology2012，，9： | 1 |
| 9 | A lithium-sulfur battery using a solid,glass-type P2S5-Li2S electrolyte显示文摘 | Marco Agostini Yuichi Aihara Takanobu Yamada | 2013 | Solid State Ionics2013，244，： | 1 |
| 10 | A prognostic role for Nm23-H1 in laryngeal carcinoma treated with postoperative radiotherapy: an introductory investigation显示文摘 | Marco Lionello Stella Blandamura Marco Agostini Claudia Staffieri Andrea Lovato Giulia Tealdo Niccolò Favaretto Luciano Giacomelli Lucio Loreggian Alberto Staffieri Gino Marioni | 2013 | European Archives of Oto-Rhino-Laryngology2013，，1： | 1 |
| 11 | 肠原性睾丸囊肿(英文)显示文摘肠原性囊肿是一种罕见的位于纵隔或腹腔中的先天性损伤。本文报道了首例肠原性睾丸囊肿。患者为一名55岁白种子人,临床表现为睾丸疼痛,左侧阴囊肿块逐渐扩大,持续2周。 | NicolaMondaini GianlucaGiubilei Simone Agostini GabriellaNesi AlessandroFranchi Marco Carini | 2006 | Asian Journal of Andrology2006，8，2： | 1 |
| 12 | New sepsis biomarkers显示文摘Sepsis remains a leading cause of death in the intensive care units and in all age groups worldwide. Early recognition and diagnosis are key to achieving improved outcomes.Therefore, novel biomarkers that might better inform clinicians treating such patients are surely needed. The main attributes of successful biomarkers would be high sensitivity,specificity, possibility of bedside monitoring and financial accessibility. A panel of sepsis biomarkers along with currently used laboratory tests will facilitate earlier diagnosis,timely treatment and improved outcome may be more effective than single biomarkers. In this review, we summarize the most recent advances on sepsis biomarkers evaluated in clinical and experimental studies. | Dolores Limongi Cartesio D'Agostini Marco Ciotti | 2016 | Asian Pacific Journal of Tropical Biomedicine2016，6，6： | 0 |
| 13 | Are liver nested stromal epithelial tumors always low aggressive?显示文摘Nested stromal-epithelial tumor(NSET) is a nonhepatocytic and non-biliary tumor of the liver consisting of nests of epithelial and spindled cells with associated myofibroblastic stroma and variable intra-lesional calcification and ossification, which represents a very rare and challenging disease. Most of the reported cases have been treated with surgery, obtaining a long survival outcome. Here, we report the case of a 31-year-old Caucasian man who underwent surgery at our institution for a large, lobulated, multinodular mass of the right hemi-liver. The histological exam confirmed the diagnosis of NSET. After 6 mo from surgery, a liver recurrence was described and a chemoembolization was performed. After a further disease progression, based on the correlation between the histological features of the disease and those of the hepatoblastoma, a similar chemotherapy regimen(with cisplatin and ifosfamide/mesna chemotherapy, omitting doxorubicin due to liver impairment) was administered. However, infection of the biliary catheter required a dose modification of the treatment. No benefit was noted and a progression of disease was radiologically assessed after only four cycles. The worsening of the clinical status prevented further treatments, and the patient died a few months later. This case report documents how the NSET might have an aggressive and non-preventable behavior. No chemotherapy schedules with a proved efficacy are available, and new data are needed to shed light on this rare neoplasm. | Tania Meletani Luca Cantini Andrea Lanese Daniele Nicolini Alessia Cimadamore Andrea Agostini Giulia Ricci Stefania Antognoli Alessandra Mandolesi Maria Guido Rita Alaggio Gian Marco Giuseppetti Marina Scarpelli Marco Vivarelli Rossana Berardi | 2017 | World Journal of Gastroenterology2017，23，46： | 0 |
| 14 | Additive Manufacturing of Ceramics from Liquid Feedstocks显示文摘In this review,we summarize the research activities carried out by our research group at the University of Padova on the additive manufacturing of ceramics from liquid feedstocks.Particularly,we evaluate the use of preceramic polymers,geopolymers,and sol-gel solutions.We mainly focus on processing with liquid feedstocks because they have some advantages with respect to slurry-based feedstocks in which powders are present.Particularly,lower viscosity,enhanced transparency,and lack of scattering and sedimentation are advantageous features for vat photopolymerization processes,whereas the absence of particulates reduces clogging problems at the nozzle for extrusion-based processes.Simultaneously,preceramic polymers and geopolymers have some limitations in terms of the range of ceramic compositions that can be obtained;sol-gel solutions are intrinsically unstable,whereas printed objects suffer from drying issues.Nevertheless,we successfully produced high-quality parts using a variety of additive manufacturing techniques,some of which(e.g.,volumetric additive manufacturing)have been proposed for the fabrication of ceramic components for the first time. | Giorgia Franchin Hamada Elsayed Renata Botti Kai Huang Johanna Schmidt Giulio Giometti Alice Zanini Anna De Marzi Marco D’Agostini Paolo Scanferla Yurun Feng Paolo Colombo | 2022 | Chinese Journal of Mechanical Engineering(Additive Manufacturing Frontiers)2022，1，1： | 0 |
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