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| 1 | Value of a comprehensive geriatric assessment for predicting one-year outcomes in patients undergoing transcatheter aortic valve implantation: results from the CGA-TAVI multicentre registry显示文摘Background In a three-month report from the CGA-TAVI registry, we found the Multidimensional Prognostic Index (MPI) and Short Physical Performance Battery (SPPB) to be of value for predicting short-term outcomes in elderly patients undergoing transcatheter aortic valve implantation (TAVI). In the present analysis, we examined the association of these tools with outcomes up to one year post-TAVI. Methods CGA-TAVI is an international, observational registry of geriatric patients undergoing TAVI. Patients were assessed using the MPI and SPPB. Efficacy of baseline values and any postoperative change for predicting outcome were established using logistic regression. Kaplan- Meier analysis was carried out for each comprehensive geriatric assessment tool, with survival stratified by risk category. Results One year after TAVI, 14.1% of patients deceased, while 17.4% met the combined endpoint of death and/or non-fatal stroke, and 37.7% the combined endpoint of death and/or hospitalisation and/or non-fatal stroke. A high-risk MPI score was associated with an increased risk of all-cause mortality (aOR = 36.13, 95% CI: 2.77–470.78, P = 0.006) and death and/or non-fatal stroke (aOR = 10.10, 95% CI: 1.48–68.75, P = 0.018). No significant associations were found between a high-risk SPPB score and mortality or two main combined endpoints. In contrast to a worsening SPPB, an aggravating MPI score at three months post-TAVI was associated with an increased risk of death and/or non-fatal stoke at one year (aOR = 95.16, 95% CI: 3.41–2657.01). Conclusions The MPI showed value for predicting the likelihood of death and a combination of death and/or non-fatal stroke by one year after TAVI in elderly patients. | Martijn S.van Mourik Nathalie van der Velde Giulio Mannarino Marie-Pierre Thibodeau Jean-Bernard Masson Gennaro Santoro Jan Baan Sofie Jansen Jana Kurucova Martin Thoenes Cornelia Deutsch ANDreas W.Schoenenberger ANDrea Ungar Peter Bramlage M Marije Vis | 2019 | Journal of Geriatric Cardiology2019，16，6： | 3 |
| 2 | Interdisciplinary forest ecosystem experiments at Soiling,Germany-from plot scale to landscape level integration显示文摘 | Martin Jansen Michael Bredemeier | 2004 | Forest Snow and Landscape Research2004，78，12： | 1 |
| 3 | Plasma carotenoids and vitamin C concentrations and risk of urothelial cell carcinoma in the European Prospective Investigation into Cancer and Nutrition12345显示文摘 | Martine M Ros H Bas Bueno-de-Mesquita Ellen Kampman Katja KH Aben Frederike L Büchner Eugene HJM Jansen Carla H van Gils Lars Egevad Kim Overvad Anne Tj?nneland Nina Roswall Marie Christine Boutron-Ruault Marina Kvaskoff Florence Perquier Rudolf Kaaks Jen | 2012 | American Journal of Clinical Nutrition2012，，4： | 1 |
| 4 | Interaction energies for the water dimer by supermolecular methods and symmetry-adapted perturbation theory: the role of bond functions and convergence of basis subsets 显示文摘 | Martin Torheyden Georg Jansen | 2000 | Theory Chem Acc2000，104，： | 1 |
| 5 | Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia显示文摘 | Sun HS Jackson MF Martin LJ Jansen K Teves L Cui H | 2009 | Nat Neurosci2009，12，10： | 1 |
| 6 | Opportunistic screening for atrial fibrillation with a single lead device in geriatric patients显示文摘Objective To determine the diagnostic yield of repeated screening for atrial fibrillation(AF)among geriatric patients.Methods A pragmatic prospective cohort study into applying opportunistic screening for AF with a handheld single lead ECG device(SLD)in a geriatric cohort.Consecutive patients of 65 years old and older visiting the geriatric outpatient clinic were eligible for inclusion.A 12 lead ECG was performed,followed by measurements with the SLD during every visit to the geriatric outpatient clinic.A frailty index was based on the accumulation of deficits model.Results 478 patients were eligible.Patients were excluded if they did not give informed consent(17 patients),had a pacemaker or implantable cardioverter defibrillator(20 patients),or had incomplete medical files(two patients).After exclusion,439 patients participated in this study.The mean age was 78 years(range 65 to 100 years),54%were female.AF was known in 89 patients(20%),first detected on the baseline ECG in four patients(1%)and first detected with the SLD in 20 patients(5%)during follow up visits.Sensitivity of the SLD was 90.0%,specificity 99.0%,negative predictive value 99.7%,and positive predictive value 73.5%.Most patients(82%)with AF were frail and 53%were severely frail.Conclusion Repeated screening in geriatric patients has a five times higher diagnostic yield than usual care.It was easily combined with usual care.Because of the positive predictive value of 73.5%,it remains necessary to confirm AF with a 12 lead ECG or 24-h Holter monitoring. | Lennaert AR Zwart Rene WMM Jansen Jacob H Ruiter Tjeerd Germans Suat Simsek Martin EW Hemels | 2020 | Journal of Geriatric Cardiology2020，17，3： | 1 |
| 7 | Synthesis and characteriza- tion of new amorphous Si/B/N/C ceramics with increased carbon content through single-source precursors显示文摘 | Thomas Jaschke Martin Jansen | 2004 | C R Chimie2004，7，： | 1 |
| 8 | Antisense Therapy: Current Status in Prostate Cancer and Other Malignancies显示文摘 | Martin Gleave Hideake Miyake Uwe Zangemeister-Wittke Burkhard Jansen | 2002 | Cancer and Metastasis Reviews2002，，1： | 1 |
| 9 | A new borazine-type single source precursor for Si/B/N/C ceramics 显示文摘 | Thomas Jaschke Martin Jansen | 2006 | J Mater Chem2006，16，： | 1 |
| 10 | Synthesis and characteriza tion of a new silaborazine derivative 显示文摘 | Hasan Cakmak Martin Jansen | 2011 | Z Anorg Allg Chem2011，637，： | 1 |
| 11 | Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML显示文摘 | Anuhar Chaturvedi Michelle Maria Araujo Cruz Nidhi Jyotsana Amit Sharma Haiyang Yun Kerstin G?rlich Martin Wichmann Adrian Schwarzer Matthias Preller Felicitas Thol Johann Meyer Reinhard Haemmerle Eduard A. Struys Erwin E. Jansen Ute Modlich Zhixiong Li L | 2013 | Blood2013，，： | 1 |
| 12 | Protection against papillomavirus with a polyuncleotide vaccine显示文摘 | Donnelly JJ Martine ZD Jansen KU | 1996 | J Infect Dis1996，173，2： | 1 |
| 13 | Soluble CD44splice variants in metastasing human breast cancer显示文摘 | Frank Jansen Johannes Bolelmann | 1997 | Int J Cancer1997，74，： | 1 |
| 14 | Contrast-enhanced Ultrasound versus Computed Tomographic Angiography for Surveillance of Endovascular Abdominal Aortic Aneurysm Repair显示文摘 | Jan A. Ten Bosch Ellen V. Rouwet Cecile T.H. Peters Linda Jansen Hence J.M. Verhagen Martin H. Prins Joep A.W. Teijink | 2010 | Journal of Vascular and Interventional Radiology2010，，： | 1 |
| 15 | Complete plastid genome sequence of the chickpea ( Cicer arietinum ) and the phylogenetic distribution of rps12 and clpP intron losses among legumes (Leguminosae)显示文摘 | Robert K. Jansen Martin F. Wojciechowski Elumalai Sanniyasi Seung-Bum Lee Henry Daniell | 2008 | Molecular Phylogenetics and Evolution2008，，3： | 1 |
| 16 | Duplication of the MECP2 Region Is a Frequent Cause of Severe Mental Retardation and Progressive Neurological Symptoms in Males显示文摘 | Hilde Van Esch Marijke Bauters Jaakko Ignatius Mieke Jansen Martine Raynaud Karen Hollanders Dorien Lugtenberg Thierry Bienvenu Lars Riff Jensen Jozef Gécz Claude Moraine Peter Marynen Jean-Pierre Fryns Guy Froyen | 2005 | The American Journal of Human Genetics2005，，3： | 1 |
| 17 | Characterization of aflatoxigenic and non-aflatoxigenic strains of Aspergillus section Flavi isolated from corn grains of different geographic origins in Brazil显示文摘 | Liliana Oliveira Rocha Gabriela Martins Reis Raquel Braghini Estela Kobashigawa Jansen Araújo Benedito Corrêa | 2012 | European Journal of Plant Pathology2012，，3： | 1 |
| 18 | Ceramic Fibers for Matrix Composites in High-Temperature Applications 显示文摘 | Baldus Peter Jansen Martin Sporn Dieter | 1999 | Science1999，285，： | 1 |
| 19 | Stochastic equations for a self-regulating gene显示文摘 | Martin Jansen | 2017 | International Journal of Biomathematics2017，10，4： | 0 |
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