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    题名 作者 年代 出处 被引量
1Alisol B 23-acetate protects against non-alcoholic steatohepatitis in mice via farnesoid X receptor activation显示文摘Alisol B 23 醋酸盐(AB23A ) 是从繁体中文药根茎 alismatis 孤立的自然 triterpenoid,它展出很多项药理学活动,包括反肝炎病毒,反癌症和抗菌剂效果。在这研究,我们检验了 AB23A 是否在位于保护的效果下面的老鼠,和机制免于非酒精的 steatohepatitis (NASH ) 。NASH 在喂的老鼠被导致蛋氨酸并且胆碱缺乏(MCD ) 节食 4 个星期。老鼠同时与 AB23A 被对待(15, 30,和 60 mg ? 潦吗?Qiang MENG Xing-ping DUAN Chang-yuan WANG Zhi-hao LIU Peng-yuan SUN Xiao-kui HUO Hui-jun SUN Jin-yong PENG Ke-xin LIU 2017Acta Pharmacologica Sinica2017,38,1:24
2Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event.TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou 2018Science China(Physics,Mechanics & Astronomy)2018,61,3:12
3Combined effect of atorvastatin and probucol on plasma cystatin C levels and severity of coronary lesion in patients with borderline coronary lesion显示文摘GE Chang-jiang LU Shu-zheng FENG Li-xia HUO Yong SONG Xian-tao CHEN Xin MENG Kang YUAN Fei 2012Chinese Medical Journal2012,,14:10
4Evaluation of surgical procedure selection based on intraoperative free portal pressure measurement in patients with portal hypertension显示文摘BACKGROUND:Various surgical procedures can be used to treat liver cirrhosis and portal hypertension.How to select the most appropriate procedure for patients with portal hypertension has become a difficult problem.This study aimed to analyze the relationship between the value of intraoperative free portal pressure(FPP)and postoperative complications,and to explore the significance of intraoperative FPP measurement with respect to surgical procedure selection.METHODS:The clinical data of 187 patients with portal hypertension who received pericardial devascularization and proximal splenorenal shunt combined with devascularization(combined operation)at the Department of General Surgery in our hospital from January 2001 to September 2008 were retrospectively analyzed.Among the patients who received pericardial devascularization,those with a postoperative FPP ≥22 mmHg were included in a high-pressure group(n=68), and those with FPP<22 mmHg were in a low-pressure group(n=49).Seventy patients who received the combined operation comprised a combined group.The intraoperative FPP measurement changes at different times,and the incidence of postoperative complications in the three groups of patients were compared.RESULTS:The postoperative FPP value in the high-pressure group was 27.5±2.3 mmHg,which was significantly higher than that of the low-pressure(20.9±1.8 mmHg)or combined groups(21.7±2.5 mmHg).The rebleeding rate in the high-pressure group was significantly higher than that in the low-pressure and combined groups.The incidence rates of postoperative hepatic encephalopathy and liver failure were not statistically different among the three groups.The mortality due to rebleeding in the low-pressure and combined groups(0.84%) was significantly lower than that of the high-pressure group.CONCLUSIONS:The study demonstrates that FPP is a critical measurement for surgical procedure selection in patients with portal hypertension.A FPP value≥22 mmHg after splenectomy and devascularization alone is an important indicator that an additional proximal splenorenal shunt needs to be performed.Sun, Yong-Wei Chen, Wei Luo, Meng Hua, Rong Liu, Wei Huo, Yan-Miao Wu, Zhi-Yong Cao, Hui 2010Hepatobiliary & Pancreatic Diseases International2010,9,3:9
5Diagnostic ability of ganglion cell complex thickness to detect glaucoma in high myopia eyes by Fourier domain optical coherence tomography显示文摘AIM:To evaluate the ability of macular ganglion cell complex(GCC) thickness using Fourier domain optical coherence tomography(FD-OCT) to detect glaucoma in highly myopic eyes.METHODS:Cross-sectional study.A total of 114 participants,consecutively were enrolled.Macular GCC thickness and peripapillary retinal nerve fiber layer(RNFL) thickness were obtained with RTVue FD-OCT.Receiver operating characteristics curves were constructed for each measurement parameter,and areas under the curves(AUCs) were compared.RESULTS:Both the average GCC and average RNFL thickness showed negative correlations with axial length(r_(GCC)=-0.404,P=0.001;r_(RNFL)=-0.561,P<0.001).The largest AUCs from GCC,and RNFL parameters were 0.968 [global loss volume(GLV)],and 0.855(average RNFL),respectively.GLV was significantly better for detecting high myopic glaucoma than average RNFL(P<0.001).CONCLUSION:Macular GCC thickness has higher diagnostic power than peripapillary RNFL thickness to discriminate glaucoma patients from non-glaucoma subjects in high myopia.Wei-Wei Wang Huai-Zhou Wang Jian-Rong Liu Xi-Fang Zhang Meng Li Yan-Jiao Huo Xin-Guang Yang 2018International Journal of Ophthalmology(English edition)2018,11,5:9
6Endovascular therapy for Acute ischemic Stroke Trial (EAST): study protocol for a prospective, multicentre control trial in China显示文摘Background and purpose:5 recent trials have shown the benefit of endovascular treatment for acute ischaemic stroke(AIS)due to large vessel occlusion of the anterior circulation.This study aims to evaluate the safety and efficacy of Solitaire thrombectomy in patients with moderate-to-severe stroke in the Chinese population,which has a high prevalence of intracranial atherosclerosis.Methods and analysis:This multicentre prospective control study will involve 17 stroke centres in China,and plans to recruit 150 patients in the intervention group,and 150 patients in the medical group,in which patients meet enrolment criteria but refuse intervention.Patients with AIS due to large vessel occlusion indicated for treatment with Solitaire stent retriever within 12 hours of symptom onset,and who meet the inclusion and exclusion criteria,will be enrolled in this study.The primary efficacy endpoint is functional independence as defined by a modified Rankin Scale(mRS)score≤2 at 90 days or by functional improvement as defined by mRS,using shift analysis.The procedural efficacy endpoint is arterial recanalisation of the occluded target vessel measured by a modified Thrombolysis in Cerebral Infarction(mTICI)score equal or superior to 2b right following the use of the study device.The primary safety endpoint is symptomatic intracranial haemorrhage(sICH)within 24±3 hours postprocedure.Ethics and dissemination:The protocol was approved by the Ethics Committee at the coordinating centre and by the local Institutional Review Board of each participating centre.Trial registration number:NCT02350283.Zhongrong Miao Xiaochuan Huo Feng Gao Xiaoling Liao Chunjuan Wang Ya Peng Yibin Cao Shengli Chen Meng Zhang Changchun Jiang Xiaoxiang Peng Cunfeng Song Liping Wei Qiyi Zhu Zaiyu Guo Li Liu Hang Lin Hua Yang Wei Wu Hui Liang Anding Xu Kangning Chen Xingquan Zhao Yuesong Pan Hao Li Liping Liu Yilong Wang Yongjun Wang EAST investigators 2016Stroke & Vascular Neurology2016,1,2:8
7Optical properties of NaY(MoO4)2:Eu3+ nanophosphors prepared by molten salt method显示文摘We synthesized NaY(MoO4)2:Eu3+phosphors of different doping concentrations by a molten salt method.This facile way possesses advantages such as simple process,lower calcination temperature(350℃)and small particle size(70 nm).The crystal system is tetragonal phase and crystal lattice is body centered.The photo luminescence measurements including emission spectra,excitation spectra and fluorescence decay curves were carried out,elucidating that NaY(MoO4)2:Eu3+can be effectively excited by near UV and blue light.Moreover,it can be concluded that Eu3+energy transfer type is exchange interaction.Huang-Rhys factor and the critical energy transfer distance(Rc)were calculated to be 0.043 and 0.995 nm,respectively.Auzel’s model was used to obtain the intrinsic radiative transition lifetime of5 D0 level(τ0=0.923 ms).Furthermore,a calculation method was used to calculate refractive index n of nontransparent NaY(MoO4)2:1 mol%Eu3+phosphor,and n was obtained to be 1.86.Lin Bai Qingyu Meng Mingxue Huo Yu Sui 2019Journal of Rare Earths2019,37,12:8
8Multiple-Element Matching Reservoir Formation and Quantitative Prediction of Favorable Areas in Superimposed Basins显示文摘在韦斯特中国的附加的盆经历了多级式的构造事件和 multicycle 烃水库形成,并且复杂的烃水库在这种类型的盆广泛地被发现了。大多数复杂的烃水库被重定位,规模重建,部件变化和阶段国家转变描绘,并且他们的分布是很困难的预言。研究显示出那地区性的 caprock (C) ,高质量的沉积外形(存款, D ) , paleohighs (山, M ) 并且来源岩石(S) 是贡献复杂的烃水库形成和西方的附加的盆的分发的四个地质的元素。四个元素的纵的顺序的联合控制烃水库形成的阶层,并且平面重迭和联合控制烃水库的范围,他们在 geohistory 的同时的联合效果决定烃水库形成的时间。多重元素的匹配水库形成介绍水库形成的一个基本模式在里面附加的盆,和我们建议它被表示为 T-CDMS。基于多重元素的匹配水库形成模式,一个全面水库形成索引(Tcdms ) 在这篇论文被开发描绘水库形成条件,和一个方法被介绍在附加的盆预言水库形成范围和出现的概率。通过新理论,方法和技术的申请,在奥陶纪的出现的有利水库形成范围和概率在四个不同水库形成时期在 Tarim 盆指向地区被预言。结果证明中央 Tarim, Yinmaili 和 Lunnan 是奥陶纪油和煤气的地可能形成了的三个很有利的区域。有当前发现的烃水库的预言结果的巧合到达 97% 。这反映新理论,方法和技术的有效性和可靠性。WANG Huaijie PANG Xiongqi WANG Zhaoming YU Qiuhua HUO Zhipeng MENG Qingyang 2010Acta Geologica Sinica(English Edition)2010,84,5:8
9Morphological and physiological traits of large-panicle rice varieties with high filled-grain percentage显示文摘Understanding the morphological and physiological traits associated with improved filling efficiency in large-panicle rice varieties is critical to devise strategies for breeding programs and cultivation management practices.Information on such traits,however,remains limited.Two large-panicle varieties with high filled-grain percentage(HF) and two check large-panicle varieties with low filled-grain percentage(LF) were field-grown in 2012 and 2013.The number of spikelets per panicle of HF and LF both exceeded 300,and the filled-grain percentage(%) of HF was approximately 90,while that of LF was approximately 75 over the two years.The results showed that when the values were averaged across two years,HF yielded 12.91 ha^(-1),while LF yielded 11.01 ha^(-1).HF had a greater leaf area duration,biomass accumulation and transport of carbohydrates stored in the culm to the grains from heading to maturity compared with LF.HF exhibited a higher leaf photosynthetic rate,more green leaves on the culm,and higher root activity during filling phase,especially during the middle and late filling phases,in relative to LF.The length of HF for upper three leaves was significantly higher than that of LF,while the angle of upper three leaves on the main culm was less in both years.Meanwhile,specific leaf weight of HF was significantly higher when compared with LF.In addition,the grain filling characteristics of HF and LF were investigated in our study.Our results suggested that a higher leaf photosynthetic rate and root activity during filling phase,greater biomass accumulation and assimilate transport after heading,and longer,thicker and more erect upper three leaves were important morphological and physiological traits of HF,and these traits could be considered as selection criterion to develop large-panicle varieties with high filled-grain percentage.MENG Tian-yao WEI Huan-he LI Chao DAI Qi-gen XU Ke HUO Zhong-yang WEI Hai-yan GUO Bao-wei ZHNAG Hong-cheng 2016Journal of Integrative Agriculture2016,15,8:6
10Novel miniature mobile cardiac catheterization laboratory for critical cardiovascular disease following natural disasters: a feasibility study显示文摘HAN Ya-ling LIANG Zhuo YAO Tian-ming SUN Jing-yang LIANG Ming HUO Yu WANG Geng, WANG Xiao-zeng LIANG Yan-chun MENG Wei-hong 2012Chinese Medical Journal2012,,6:5
11Cilastatin protects against imipenem-induced nephrotoxicity via inhibition of renal organic anion transporters(OATs)显示文摘Imipenem is a carbapenem antibiotic. However, Imipenem could not be marketed owing to its instability and nephrotoxicity until cilastatin, an inhibitor of renal dehydropeptidase-I(DHP-I),was developed. In present study, the potential roles of renal organic anion transporters(OATs) in alleviating the nephrotoxicity of imipenem by cilastatin were investigated in vitro and in rabbits. Our results indicated that imipenem and cilastatin were substrates of h OAT1 and h OAT3. Cilastatin inhibited h OAT1/3-mediated transport of imipenem with IC50 values comparable to the clinical concentration, suggesting the potential to cause a clinical drug–drug interaction(DDI). Moreover,imipenem exhibited h OAT1/3-dependent cytotoxicity, which was alleviated by cilastatin and probenecid. Furthermore, cilastatin and probenecid ameliorated imipenem-induced rabbit acute kidney injury, and reduced the renal secretion of imipenem. Cilastatin and probenecid inhibited intracellular accumulation of imipenem and sequentially decreased the nephrocyte toxicity in rabbit primary proximal tubule cells. Renal OATs, besides DHP-I, was also the target of interaction between imipenem and cilastatin, and contributed to the nephrotoxicity of imipenem. This therefore gives in part the explanation about the mechanism by which cilastatin protected against imipenem-induced nephrotoxicity. Thus, OATs can potentially be used as a therapeutic target to avoid the renal adverse reaction of imipenem in clinic.Xiaokui Huo Qiang Meng Changyuan Wang Yanna Zhu Zhihao Liu Xiaodong Ma Xiaochi Ma Jinyong Peng Huijun Sun Kexin Liu 2019Acta Pharmaceutica Sinica B2019,9,5:5
12Ionic liquid crystal-based electrolyte with enhanced charge transport for dye-sensitized solar cells显示文摘A room temperature ionic liquid crystal,1-dodecyl-3-ethylimidazolium iodide(C12EImI),and an ionic liquid,1-decyl-3-ethylimidazolium iodide(C10EImI),have been synthesized,characterized and employed as the electrolyte for dye-sensitized solar cells(DSSC).The physicochemical properties show that a smectic A(SmA)phase with a lamellar structure is formed in C12EImI.Both C12EImI and C10EImI have good electrochemical and thermal stability facilitating their use in DSSC.The steady-state voltammograms reveal that the diffusion coefficient of I3–in C12EImI is larger than that in C10EImI,which is attributed to the existence of the SmA phase in C12EImI.Because the iodide species are located between the layers of imidazolium cations in C12EImI,exchange reaction-based diffusion is increased with a consequent increase in,the overall diffusion.The electrochemical impedance spectrum reveals that charge recombination at the dyed TiO2/electrolyte interface of a C12EImI-based DSSC is reduced due to the increase in I3–diffusion,resulting in higher open-circuit voltage.Moreover,both short-circuit current density and fill factor of the C12EImI based DSSC increase,as a result of the increasing transport of I3–in C12EImI.Consequently,the photoelectric conversion efficiency of C12EImI-based DSSC is higher than that of the C10EImI–based DSSC.PAN Xu WANG Meng FANG XiaQing ZHANG ChangNeng HUO ZhiPeng DAI SongYuan 2013Science China Chemistry2013,56,10:4
13Plasmon-tunable Au@Ag core-shell spiky nanoparticles for surfaceenhanced Raman scattering显示文摘A facile synthetic approach has been developed to prepare uniform and size-tunable spiky Au@Ag core-shell nan oparticles (NPs) to tailor the localized surface plasm on res onance (LSPR) properties. The gradual assembly of small Au nano crystals allows the size of spiky Au NPs to be modulated from tens to several hundreds of nano meters by tuning the concentration of initial Au seeds and Au source;and the thick ness of the Ag shell can be adjusted with stepwise reduction of Ag(l)ions. The LSPR bands of such spiky Au@Ag core-shell NPs resemble those of pure spiky Au NP cores of similar sizes in near-infrared region, and increasing the Ag shell thickness results in a blue shift and broadening of the LSPR band in the n ear-i nfrared regi on. Additi on ally, the spiky Au@Ag core-shell NPs exhibit improved surface-e nhan ced Rama n scattering (SERS) activity as compared to the bare spiky Au NPs and spherical Ag@Au NPs. This work has offered a facile route to synthesize plasmonic metal NPs with LSPR band in 650 to 800 nm that show strong enhancement of localized electromagnetic field, which provides an effective SERS substrate for SERS imaging and detection in biological fluids and tissues.Zhulin Huang Guowen Meng Xiaoye Hu Qijun Pan Dexian Huo Hongjian Zhou Yan Ke Nianqiang Wu 2019Nano Research2019,12,2:4
14Design and fabrication of a low modulus β-type Ti-Nb-Zr alloy by controlling martensitic transformation显示文摘In this paper, high density of dislocations, grain boundaries and nanometer-scale a precipitates were introduced to a metastable Ti-36Nb-5Zr alloy (wt%) through a thermo-mechanical approach including severe cold rolling and short-time annealing treatment. The martensitic transformation was retarded, and theβphase with low content ofβstabilizers was retained at room temperature after the thermo-mechanical treatment. As a result, both low modulus (57 GPa) and high strength (950 MPa) are obtained.The results indicate that it is a feasible strategy to control martensitic transformation start temperature through micros true ture optimization instead of composition design,with the aim of fabricating low modulusβ-type Ti alloy.Qing-Kun Meng Yu-Fei Huo Wen Ma Yan-Wei Sui Jin-Yong Zhang Shun Guo Xin-Qing Zhao 2018Rare Metals2018,37,9:4
15An in situ ATR-FTIR study of mixed collectors BHA/DDA adsorption in ilmenite-titanaugite flotation system显示文摘This paper researched the enhanced flotation separation performance of ilmenite and titanaugite using the mixed collector benzhydroxamic acid/dodecylamine(BHA/DDA).The interface assembly mechanism was mainly investigated through in situ attenuated total reflectance Fourier transform infrared(ATRFTIR)spectroscopy combined with the two-dimensional correlation spectroscopy(2D-COS)and X-ray photoelectron spectroscopy(XPS).It has been found that BHA/DDA mixed collectors successfully separate ilmenite from titanaugite at a molar ratio of 8:1.Zeta potential experiments suggested that,in the presence of mixed collector system,the BHA-DDA complex adsorbed on the ilmenite surface via the chemically adsorbed BHA and the electrostatically adsorbed DDA,however,the complex adsorbed on the surface of titanaugite unstably.According to in situ ATR-FTIR combined with 2D-COS and XPS results,the interface assembly mechanism of BHA/DDA is summarized as:the function group of BHA molecules first binds to the metal sites on minerals to form bidentate ligand,then DDA co-adsorbed with BHA on the surface of minerals through hydrogen bonding.DDA may change the adsorption modes of some BHA on the ilmenite surface from four-membered ring to five-membered ring,while the modes on the titanaugite surface is true opposite.Finally,recommended adsorption configurations of the BHA/DDA complex on the two mineral surfaces are proposed.Liping Luo Houqin Wu Longhua Xu Jinping Meng Jiahui Lu Huan Zhou Xiaomei Huo Lingyun Huang 2021International Journal of Mining Science and Technology2021,31,4:4
16Organic anion transporters also mediate the drug–drug interaction between imipenem and cilastatin显示文摘This study aimed to clarify that organic anion transporters(OATs)mediate the drug–drug interaction(DDI)between imipenem and cilastatin.After co-administration with imipenem,the plasma concentrations and the plasma concentration-time curve(AUC)of cilastatin were significantly increased,while renal clearance and cumulative urinary excretion of cilastatin were decreased.At the same time,imipenem significantly inhibited the uptake of cilastatin in rat kidney slices and in human OAT1(hOAT1)-HEK293 and human OAT3(hOAT3)-HEK293 cells.Probenecid,p-aminohippurate,and benzylpenicillin inhibited the uptake of imipenem and cilastatin in rat kidney slices and in hOAT1-and hOAT3-HEK 293 cells,respectively.The uptakes of imipenem and cilastatin in hOAT1-and hOAT3-HEK 293 cells were significantly higher than that in mock-HEK-293 cells.Moreover,the K m values of cilastatin were increased in the presence of imipenem with unchanged V max,indicating that imipenem inhibited the uptake of cilastatin in a competitive manner.When imipenem and cilastatin were co-administered,the level of imipenem was higher compared with imipenem alone both in vivo and in vitro.But,cilastatin significantly inhibited the uptake of imipenem when dehydropeptidase-1(DPEP1)was silenced by RNAi technology in hOAT1-and hOAT3-HEK 293 cells.In conclusion,imipenem and cilastatin are the substrates of OAT1 and OAT3.OAT1 and OAT3 mediate the DDI between imipenem and cilastatin.Meanwhile,cilastatin also reduces the hydrolysis of imipenem by inhibiting the uptake of imipenem mediated by OAT1 and OAT3 in the kidney as a complement.Yanna Zhu Xiaokui Huo Changyuan Wang Qiang Meng Zhihao Liu Huijun Sun Aiping Tan Xiaodong Ma Jinyong Peng Kexin Liu 2020Asian Journal of Pharmaceutical Sciences2020,15,2:3
17Synthesis of ITQ-2 zeolite under static conditions and its properties显示文摘Using silica gel as the precursor, MCM-22(p) was synthesized under the static conditions. Then ITQ-2 zeolite was obtained by using n-cetyltrimethylammonium bromide (CTAB) and tetrapro- pylammonium hydroxide (TPAOH) as the swelling agents to swell the pores of MCM-22(p). The ob- tained zeolite was characterized by XRD, SEM, BET, NH3-TPD. The results show that the zeolite had the best swelling when MCM-22(p):CTAB:TPAOH=1:4:1. The synthesis duration and temperature did not influence significantly the pore swelling. Except TPAOH, CTAB can also be used together with tetrabuthylammonium hydroxide (TBAOH) as the pore swelling agent. There was contribution of sur- face area and pore volume from the mesoporous pores in the ITQ-2 zeolite and it also showed weaker acidity than MCM-22. However, the ITQ-2 supported NiW catalyst showed higher activity and selec- tivity to the middle distillates in the hydrocracking of vacuum gasoil (VGO) than MCM-22 supported catalyst. This implied that the diffusion of large molecules of heavy oil in the catalyst was facilitated due to the presence of the mesoporous pores and hence higher activity and selectivity to middle dis- tillates.LIU Baijun HUO Huijuan MENG Qingmin GAO Shansong 2006Science China Chemistry2006,49,2:3
18Polydopamine/poly(sulfobetaine methacrylate)Co-deposition coatings triggered by CuSO_(4)/H_(2)O_(2)on implants for improved surface hemocompatibility and antibacterial activity显示文摘Implanted biomaterials such as medical catheters are prone to be adhered by proteins,platelets and bacteria due to their surface hydrophobicity characteristics,and then induce related infections and thrombosis.Hence,the development of a versatile strategy to endow surfaces with antibacterial and antifouling functions is particularly significant for blood-contacting materials.In this work,CuSO_(4)/H_(2)O_(2)was used to trigger polydopamine(PDA)and poly-(sulfobetaine methacrylate)(PSBMA)co-deposition process to endow polyurethane(PU)antibacterial and antifouling surface(PU/PDA(Cu)/PSBMA).The zwitterions contained in the PU/PDA(Cu)/PSBMA coating can significantly improve surface wettability to reduce protein adsorption,thereby improving its blood compatibility.In addition,the copper ions released from the metal-phenolic networks(MPNs)imparted them more than 90%antibacterial activity against E.coli and S.aureus.Notably,PU/PDA(Cu)/PSBMA also exhibits excellent performance in vivo mouse catheter-related infections models.Thus,the PU/PDA(Cu)/PSBMA has great application potential for developing multifunctional surface coatings for blood-contacting materials so as to improve antibacterial and anticoagulant properties.Zhongqiang Zhu Qiang Gao Ziyue Long Qiuyi Huo Yifan Ge Ntakirutimana Vianney Nishimwe Anodine Daliko Yongchun Meng Jia Qu Hao Chen Bailiang Wang 2021Bioactive Materials2021,6,8:3
19Estimation of the Land Surface Emissivity in the Hinterland of Taklimakan Desert显示文摘An accurate accounting of land surface emissivity(ε) is important both for the retrieval of surface temperatures and the calculation of the longwave surface energy budgets.Since ε is one of the important parameterizations in land surface models(LSMs),accurate accounting also improves the accuracy of surface temperatures and sensible heat fluxes simulated by LSMs.In order to obtain an accurate emissivity,this paper focuses on estimating ε from data collected in the hinterland of Taklimakan Desert by two different methods.In the first method,ε was derived from the surface broadband emissivity in the 8–14 μm thermal infrared atmospheric window,which was determined from spectral radiances observed by field measurements using a portable Fourier transform infrared spectrometer,the mean ε being 0.9051.The second method compared the observed and calculated heat fluxes under nearneutral atmospheric stability and estimated ε indirectly by minimizing the root-mean-square difference between them.The result of the second method found a mean value of 0.9042,which is consistent with the result by the first method.Although the two methods recover ε from different field experiments and data,the difference of meanvalues is 0.0009.The first method is superior to the indirect method,and is also more convenient.LIU Yong-qiang Ali MAMTIMIN HUO Wen YANG Xing-hua LIU Xin-chun MENG Xian-yong HE Qing 2014Journal of Mountain Science2014,11,6:3
20Overexpression of Hdac6 enhances resistance to virus infection in embryonic stem cells and in mice显示文摘亲爱的编辑,Dekun Wang Qingwen Meng Lihong Huo Meng Yang Lingling Wang Xinyu Chen JianchaoWang Zhiguo Li Xiaoying Ye Na Liu Qiuyan Li Zhen Dai Hongsheng Ouyang Ning Li Jun Zhou Lingyi Chen Lin Liu 2015Protein & Cell2015,6,2:3
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