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| 1 | The cytotoxicity and protective effects of Astragalus membranaceus extracts and butylated hydroxyanisole on hydroxyl radical-induced apoptosis in fish erythrocytes显示文摘Erythrocytes play an essential role in transporting O_2 and CO_2 for respiration in fish. However,erythrocytes continuously suffer from reactive oxygen species(ROS)-induced oxidative stress and apoptosis. Thus, it is essential to expand our knowledge of how to protect erythrocytes against ROS-induced oxidative stress and apoptosis in fish. In this study, we explored the cytotoxicity and the effects of butylated hydroxyanisole(BHA), ethyl ether extracts, ethyl acetate extracts, acetone extracts(AE), ethanol extracts, and aqueous extracts of Astragalus membranaceus(EAm) on hydroxyl radical(·OH)-induced apoptosis in carp erythrocytes. The rat hepatocytes and carp erythrocytes were incubated with different concentrations of BHA or EAm(0.125 to 1 mg/mL). The toxicity in rat hepatocytes and carp erythrocytes was then measured using a 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide(MTT) assay and a haemolysis assay,respectively. The carp erythrocytes were treated with BHA or EAm in the presence of 40 μmol/L FeSO4 and20 μmol/L H_2 O_2 at 37℃, except for the control group. Oxidative stress and apoptosis parameters in the carp erythrocytes were then evaluated using the commercial kit. The results indicated that at high concentrations, BHA and EAm could induce toxicity in rat hepatocytes and fish erythrocytes. However, BHA was more toxic than EAm at the same concentrations. Moreover, the toxicity order of BHA and EAm in the fish erythrocytes approximately agreed with that for the rat hepatocytes. Butylated hydroxyanisole and EAm suppressed the ·OH-induced phosphatidylserine exposure and DNA fragmentation(the biomarkers of apoptosis) by decreasing the generation of ROS, inhibiting the oxidation of cellular components, and restoring the activities of antioxidants in carp erythrocytes. Of all of the examined EAm, the AE showed the strongest effects. The effects of AE on superoxide anion, H_2 O_2, met-haemoglobin and reduced glutathione levels, as well as glutathione reductase activity and apoptosis were equivalent to or stronger than those of BHA. These results revealed that the AE of Astragalus membranaceus could be used as a potential natural antioxidant or apoptosis inhibitor in fish erythrocytes. | Huatao Li Xiaoqiu Zhou Min Wu Mengling Deng Chao Wang Jingjing Hou Pengju Mou | 2016 | Animal Nutrition2016，，4： | 5 |
| 2 | A continuous and high-efficiency process to separate coal bed methane with porous ZIF-8 slurry:Experimental study and mathematical modelling显示文摘Coal bed methane has been considered as an important energy resource.One major difficulty of purifying coal bed methane comes from the similar physical properties of CH_4 and N_2.The ZIF-8/water-glycol slurry was used as a medium to separate coal bed methane by fluidifying the solid adsorbent material.The sorption equilibrium experiment of binary mixture(CH_4/N_2)and slurry was conducted.The selectivity of CH_4 to N_2 is within the range of 2-6,which proved the feasibility of the slurry separation method.The modified Langmuir equation was used to describe the gas-slurry phase equilibrium behavior,and the calculated results were in good agreement with the experimental data.A continuous absorption-adsorption and desorption process on the separation of CH_4/N_2 in slurry is proposed and its mathematical model is also developed.Sensitivity analysis is conducted to determine the operation conditions and the energy performance of the proposed process was also evaluated.Feed gas contains 30 mol%of methane and the methane concentration in product gas is 95.46 mol%with the methane recovery ratio of 90.74%.The total energy consumption for per unit volume of product gas is determined as 1.846 kWh Nm^(-3).Experimental results and process simulation provide basic data for the design and operation of pilot and industrial plant. | Wan Chen Xiaonan Guo Enbao Zou Mengling Luo Mengzijing Chen Mingke Yang Hai Li Chongzhi Jia Chun Deng Changyu Sun Bei Liu Lanying Yang Guangjin Chen | 2020 | Green Energy & Environment2020，5，3： | 5 |
| 3 | Anisotropic NdFeB/SmCoCuFeZr composite bonded magnet prepared by warm compaction process显示文摘Anisotropic NdFeB/SmCoCuFeZr composite bonded magnets were prepared by warm compaction process. The effects of adding SmCoCuFeZr magnetic powder on the properties of anisotropic bonded NdFeB magnet were investigated in this work. The results show that, both magnetic properties and temperature stability of the bonded magnet can be improved by adding fine SmCoCuFeZr magnetic powder. In the present study, the optimal content of SmCoCuFeZr magnetic powder was about 20 wt.%, in this case, the Br, Hcj, and(BH)maxof the NdFeB/SmCoCuFeZr composite magnet achieved 0.943 T, 1250 kA/m, and168 kJ/m^3, respectively. | Mengling Wu Yuping Li Xin Wang Lizhao Chen Yaozhao Mu | 2017 | Journal of Rare Earths2017，35，12： | 4 |
| 4 | Advances in Studies on Interaction between Selenium and Heavy Metal Cadmium显示文摘Selenium is an essential functional element of the human body,and the issue of selenium accompanying heavy metals is receiving much concern.This paper expounded the form of existence of selenium and cadmium in soil and influencing factors of their bioavailability,and further elaborated the interaction between selenium and cadmium.On the basis,it provided references for further studies on the interaction between selenium and cadmium,and provided basis for establishing selenium-enriched barrier technology for crops. | Liping PAN Yongxian LIU Yanfei HUANG Mengling NONG Shiyang LU Jinping CHEN Yuying ZHAO Liumei XIONG Xiu LAN Kebing LI | 2017 | Asian Agricultural Research2017，9，8： | 3 |
| 5 | Rail temperature rise characteristics caused by linear eddy current brake of high-speed train显示文摘The rail temperature rises when the linear eddy current brake of high-speed train is working,which may lead to a change of rail physical characteristics or an effect on train operations.Therefore,a study concerning the characteristics of rail temperature rise caused by eddy current has its practical necessity.In the research,the working principle of a linear eddy current brake is introduced and its FEA model is established.According to the generation mechanism of eddy current,the theoretical formula of the internal energy which is produced by the eddy current is deduced and the thermal load on the rail is obtained.ANSYS is used to simulate the rail temperature changes under different conditions of thermal loads.The research result shows the main factors which contribute to the rising of rail temperature are the train speed,brake gap and exciting current.The rail temperature rises non-linearly with the increase of train speed.The rail temperature rise curve is more sensitive to the exciting current than the air gap.Moreover,the difference stimulated by temperature rising between rails of 60 kg/m and 75 kg/m is presented as well. | Xiaoshan Lu Yunfeng Li Mengling Wu Jianyong Zuo Wei Hu | 2014 | Journal of Traffic and Transportation Engineering(English Edition)2014，1，6： | 3 |
| 6 | The Pumilio RNA-binding protein APUM24 regulates seed maturation by fine-tuning the BPM-WRI1 module in Arabidopsis显示文摘Pumilio RNAbindingproteinsparticipateinmes-senger RNA(mRNA)degradation and t ranslational repression,but their roles in plant development are largely unclear.Here,we show that Arabidopsis PUMILIO PROTEIN24(APUM24),an atypical Pumiliohomology domaincontaining protein,plays an im-portant part in regulating seed maturation,a major stage of plant development.APUM24 is strongly expressed in maturing seeds.Reducing APUM24 expression resulted in abnormal seed maturation,wrinkled seeds,and lower seed oil contents,and APUM24 knockdown resulted in lower levels of WRINKLED 1(WRI1),a key transcription factor con-trolling seed oil accumulation,and lower expression of WRI1 target genes.APUM24 reduces the mRNA stability of BTB/POZMATH(BPM)family genes,thus decreasing BPM protein levels.BPM is responsible for the 26S proteasomemediated degradation of WRI1 and has important functions in plant growth and development.The 3′untranslated regions of BPM family genes contain putative Pumilio response elements(PREs),which are bound by APUM24.Re-duced BPM or increased WRI1 expression rescued the decient seed maturation of apum242 knock-down mutants,and APUM24 overexpression re-sulted in increased seed size and weight.Therefore,APUM24 is crucial to seed maturation through its action as a positive regulatornetuning the BPMWRI1 module,making APUM24 apromising target for breeding strategies to increase crop yields. | Ruihua Huang Mengling Liu Guanping Gong Pingzhi Wu Barunava Patra Ling Yuan Hongting Qin Xiaoxu Wang Guohe Wang Huimei Liao Lu Gao Chengwei Yang Hongqing Li Shengchun Zhang | 2021 | Journal of Integrative Plant Biology2021，63，7： | 2 |
| 7 | Partial root-zone irrigation enhanced soil enzyme activities and water use of maize under different ratios of inorganic to organic nitrogen fertilizers显示文摘 | Fusheng Li Jiangmin Yu Mengling Nong Shaozhong Kang Jianhua Zhang | 2009 | Agricultural Water Management2009，，2： | 2 |
| 8 | Exponential stability of the Euler-Maruyama method for neutral stochastic functional differential equations with jumps显示文摘The exponential stability of trivial solution and numerical solution for neutral stochastic functional differential equations(NSFDEs) with jumps is considered. The stability includes the almost sure exponential stability and the mean-square exponential stability. New conditions for jumps are proposed by means of the Borel measurable function to ensure stability. It is shown that if the drift coefficient satisfies the linear growth condition, the Euler-Maruyama method can reproduce the corresponding exponential stability of the trivial solution. A numerical example is constructed to illustrate our theory. | Haoyi MO Mengling LI Feiqi DENG Xuerong MAO | 2018 | Science China(Information Sciences)2018，61，7： | 2 |
| 9 | Basic theory and stability analysis for neutral stochastic functional differential equations with pure jumps显示文摘This paper investigates the existence and uniqueness of solutions to neutral stochastic functional differential equations with pure jumps(NSFDEwPJs). The boundedness and almost sure exponential stability are also considered. In general, the classical existence and uniqueness theorem of solutions can be obtained under a local Lipschitz condition and linear growth condition. However, there are many equations that do not obey the linear growth condition. Therefore, our first aim is to establish new theorems where the linear growth condition is no longer required whereas the upper bound for the diffusion operator will play a leading role. Moreover, the pth moment boundedness and almost sure exponential stability are also obtained under some loose conditions. Finally, we present two examples to illustrate the effectiveness of our results. | Mengling LI Feiqi DENG Xuerong MAO | 2019 | Science China(Information Sciences)2019，62，1： | 2 |
| 10 | Effects of alternate partial root-zone irrigation on yield and water use of sticky maize with fertigation显示文摘 | Hailing Liang Fusheng Li Mengling Nong | 2013 | Agricultural Water Management2013，，： | 1 |
| 11 | Partial root-zone irrigation enhanced soil enzyme activities and water use of maize under different ratios of inorganic to organic nitrogen fertilizers显示文摘 | Fusheng Li Jiangmin Yu Mengling Nong Shaozhong Kang Jianhua Zhang | 2009 | Agricultural Water Management2009，，2： | 1 |
| 12 | Elevated expression of CAPON and neuronal nitric oxide synthase in the sciatic nerve of rats following constriction injury显示文摘 | Zhiming Cui Qingshan Lv Meijuan Yan Chun Cheng Zhiqin Guo Junling Yang Mengling Chen Yinyin Xia Li Zhang Aiguo Shen | 2010 | The Veterinary Journal2010，，3： | 1 |
| 13 | Development of a new fluorescent probe : 1,3,5,7-tetramethyl-8-(4 -aminophenyl)-4,4-difluoro-4-bora-3a,4a-diaza-s-indacence for the determination of trace nitrite显示文摘 | Mengling Li Hong Wang Xian Zhang Hua-shan Zhang | 2004 | Spectrochimica Acta Part A2004，，60： | 1 |
| 14 | β-Cyclodextrin carbon-based nanoparticles with a core-shell-shell structure for efficient adsorption of crystal violet and bisphenol A显示文摘Textile wastewater contains highly toxic,nondegradable,carcinogenic organic pollutants,causing severe damage to the ecological environment.In this work,β-cyclodextrin carbon-sphere-based nanocomposite(CS/SiO_(2)@β-CD)with a core-shell-shell configuration was prepared by hydrothermal synthesis and subsequent sedimentation-azeotropic distillation with SiO_(2)as intermediate layer for the removal of crystal violet(CV)and bisphenol A(BPA).The chemical structure and morphology of the CS/SiO_(2)@β-CD were characterized by FT-IR,SEM and TEM.The effects of contact time,pH,temperature and initial concentration of the absorbates on the adsorption property were explored.The CS/SiO_(2)@β-CD showed excellent adsorption capacity on CV and BPA,and the maximum adsorption capacity was 87.873 mg g^(-1)and 165.095 mg g^(-1),respectively.Their adsorption process was in line with the pseudo-second-order and pseudo-first-order kinetic models,respectively.The adsorption thermodynamics could be better fitted by Langmuir model than by Freundlich model.The calculated thermodynamic parameters(-ΔG0,ΔS0 andΔH0)illustrated the adsorption of CV was endothermic,in contrast,the adsorption of BPA was exothermic process.Furthermore,the CS/SiO_(2)@β-CD showed excellent recovery performance,making it a potential adsorbent for the practical treatment of textile wastewater. | Tian Tian Mengling Liu Yinhui Li Jian Han Liang Ren Heike Lorenz Qing Wu Jianxin Chen | 2022 | Particuology2022，20，3： | 1 |
| 15 | Local modeling approach for spatially distributed system based on interval type-2 T-S fuzzy sets显示文摘 | WANG Mengling LINing LI Shaoyuan | | 0，，09： | 1 |
| 16 | Genetic diversity and molecular phylogeny of Planktothrix (Oscillatoriales, cyanobacteria) strains from China显示文摘 | Shen Lin Zhongxing Wu Gongliang Yu Mengling Zhu Boshi Yu Renhui Li | 2009 | Harmful Algae2009，，1： | 1 |
| 17 | AHA1 upregulates IDH1 and metabolic activity to promote growth and metastasis and predicts prognosis in osteosarcoma显示文摘Osteosarcoma(OS)is the most common primary malignant bone tumor in children and adolescents.Although activator of HSP90 ATPase activity 1(AHA1)is reported to be a potential oncogene,its role in osteosarcoma progression remains largely unclear.Since metabolism reprogramming is involved in tumorigenesis and cancer metastasis,the relationship between AHA1 and cancer metabolism is unknown.In this study,we found that AHA1 is significantly overexpressed in osteosarcoma and related to the prognosis of osteosarcoma patients.AHA1 promotes the growth and metastasis of osteosarcoma both in vitro and in vivo.Mechanistically,AHA1 upregulates the metabolic activity to meet cellular bioenergetic needs in osteosarcoma.Notably,we identifed that isocitrate dehydrogenase 1(IDH1)is a novel client protein of Hsp90 AHA1.Furthermore,the IDH1 protein level was positively correlated with AHA1 in osteosarcoma.And IDH1 overexpression could partially reverse the effect of AHA1 knockdown on cell growth and migration of osteosarcoma.Moreover,high IDH1 level was also associated with poor prognosis of osteosarcoma patients.This study demonstrates that AHA1 positively regulates IDH1 and metabolic activity to promote osteosarcoma growth and metastasis,which provides novel prognostic biomarkers and promising therapeutic targets for osteosarcoma patients. | Diwei Zheng Weihai Liu Wenlin Xie Guanyu Huang Qiwei Jiang Yang Yang Jiarong Huang Zihao Xing Mengling Yuan Mengning Wei Yao Li Junqiang Yin Jingnan Shen Zhi Shi | 2021 | Signal Transduction and Targeted Therapy2021，6，2： | 1 |
| 18 | Molecular phylogenomic analysis reveals a single origin of monkeypox virus transmission in Guangzhou,China in June 2023显示文摘The monkeypox(mpox)virus has caused worldwide transmission since its initial report in England in early May 2022.Available data from the World Health Organization(WHO)show that Europe and the Americas experienced a huge wave of mpox virus infection.Now the number of infected cases is on the rise in Asia.Several sporadic infections have been reported in China.In this study,we obtained high‐quality whole viral genomic sequences using a mpox virus‐specific amplicon‐based sequencing strategy.Our analysis of the phylogenomic characteristics indicated that all eight mpox virus sequences from Guangzhou belonged to the clade IIb lineage B.1.3 cluster.However,we could not locate the exact origins where the virus was imported,based on all the available mpox virus sequences from the Global Initiative on Sharing Avian Influenza Data(GISAID)database(http://gffzz25fa773688d24fb7sv0fko50b5wbx6ouo.ffgz.tsg.suse.edu.cn/),except for their closest sequence similarity to that was reported from Japan.Novel amino acid mutations were found among the eight cases,suggesting that a local transmission may have occurred in Guangzhou,China. | Mengling Jiang Xizi Deng Qinghong Fan Fei Gu Huiqin Yang Jian Wang Xiaoping Tang Fengyu Hu Yun Lan Feng Li | 2023 | Biosafety and Health2023，5，5： | 0 |
| 19 | A model for aircraft cabin evacuation considering passenger type显示文摘Pedestrian safety evacuation in aircraft cabins has been a challenging problem because of the aircraft’s unique characteristics,such as the diversity of passengers and the restricted evacuation environment.It is difficult to reproduce evacuation activities in aircraft cabin due to safety concerns and cost constraints.To fill this gap,an improved cellular automaton model of crowd evacuation for aircraft cabin is established by incorporating the characteristics of cabin space structures and passenger attributes.Passengers are divided into healthy individual passengers and disabled-healthy group passengers,whose movement mechanisms are quantified.Based on the constructed model,simulation experiments are conducted using the configuration cabin layout of B737-800 as an example.The results show that the evacuation time is prolonged with increased passenger density and the number of disabled passengers.Moreover,the overall evacuation time is insignificantly affected by whether disabled-healthy group passengers’seats are close to the aisle or window,and the evacuation efficiency is best when their seats are evenly distributed in the cabin.The evacuation time is the shortest when all cabin doors are open,and pedestrians are evacuated the slowest when the central emergency doors are closed.This study pro-vides valuable insights into effective strategies for pedestrian evacuation and crowd emergency management of civil aircraft. | Yaping Ma Jinfeng Yuan Lingling Tan Quanyi Liu Mengling Li | 2024 | Journal of Safety Science and Resilience2024，5，1： | 0 |
| 20 | Research on the Revitalization of Rural Talents under the Strategy of Rural Revitalization显示文摘Since the implementation of the rural revitalization strategy,it has provided multiple assistance for the development of the vast number of villages in China.Talents are the key to the revitalization and development of the countryside.Only when a large number of high-quality talents take root in the countryside and help the rural construction in different fields can we give full play to the role of talents in promoting rural development.This paper takes the rural areas of China as the research object,analyzes the current situation of the development of rural talents,discusses the problems existing in the development of rural human resources,and puts forward effective measures for the revitalization of rural talents,to provide a solid theoretical basis for the better development of the countryside. | Xinsheng LI Minghua GU Neng CHEN Yongxian LIU Mengling NONG Yimiao LI Ya ZHANG Qijun WEN Yilin WANG Wei LIU Lishan HE | 2021 | Asian Agricultural Research2021，13，6： | 0 |
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