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| 1 | Forced Convection Heat Transfer in Porous Structure: Effect of Morphology on Pressure Drop and Heat Transfer Coefficient显示文摘A light-weight structure with sufficient mechanical strength and heat transfer performance is increasingly required for some thermal management issues.The porous structure with the skeleton supporting the ambient stress and the pores holding the flowing fluid is considered very promising,attracting significant scientific and industrial interest over the past few decades.However,due to complicated morphology of the porous matrices and thereby various performance of the pressure drop and heat transfer coefficients (HTC),the comprehensive comparison and evaluation between different structures are largely unclear.In this work,recent researches on the efforts of forced convection heat transfer in light-weight porous structure are reviewed;special interest is placed in the open-cell foam,lattice-frame,structured packed bed,and wire-woven structures.Their experimental apparatus,morphological of the porous structures,effect of morphology on pressure drop and HTC,and further applications are discussed.The new method which measure morphology accurately should be paid more attention to develop more accuracy correlation.Also,the most research focused on low Reynolds number and existing structure,while very few researchers investigated the property of forced convection heat transfer in high velocity region and developed new porous structure. | ZHAO Jiafei SUN Mingrui ZHANG Lunxiang HU Chengzhi TANG Dawei YANG Lei SONG Yongchen | 2021 | Journal of Thermal Science2021,30,2: | 4 |
| 2 | Controlling the lateral and vertical dimensions of Bi2Se3 nanoplates via seeded growth显示文摘nanostructures 的形态学的调整经常是一项令人满意却挑战性的任务。我们采用了播种生长方法并且导致了运动控制综合双性人 < 潜水艇 class= “ a-plus-plus ” > 2 Se < 潜水艇 class= “ a-plus-plus ” > 有可修改的形态学的 3 nanoplates。由操作先锋答案与注射泵在被注入种子答案的率,二个特殊生长模式能被认识到。与快注射,双性人的厚度<潜水艇class=“ a-plus-plus ”> 2 Se <潜水艇class=“ a-plus-plus ”>当边长度从 160 nm (种子)长大了到 12 m 时, 3 nanoplates 稍微从 7.5 nm (种子)增加了到 9.5 nm ,在播种生长的 6 个连续回合以后。与慢注射,厚度和边长度分别地在 6 轮生长以后同时增加了到 35 nm 和 6 m。这二个模式能被看作在原子免职和表面移植之间的一场比赛。产品出现了有趣,厚度依赖者拉曼性质。另外, NIR 透明,高度传导性、灵活的双性人<潜水艇class=“ a-plus-plus ”> 2 Se <潜水艇class=“ a-plus-plus ”> 3 有不同厚度的薄电影被同样综合的双性人的集会构造<潜水艇class=“ a-plus-plus ”> 2 Se <潜水艇class=“ a-plus-plus ”> 3 nanoplates 。这条途径能显著地与多样的形态学基于播种生长和运动控制支持万用的 nanostructures 的发展。 | Awei Zhuang Yuzhou Zhao Xianli Liu Mingrui Xu Youcheng Wang Unyong Jeong Xiaoping Wang Jie Zeng | 2015 | Nano Research2015,8,1: | 1 |
| 3 | SHED: Stem cells from human exfoliated deciduous teeth显示文摘 | Miura M Gronthos S Mingrui Zhao | 2003 | PNAS2003,100,10: | 1 |
| 4 | Author Correction:Evolutionarily conservative and non-conservative regulatory networks during primate interneuron development revealed by single-cell RNA and ATAC sequencing显示文摘Correction to:Cell Research http://gffzzd3cc09b8251d45dfsbc9q65nfc00b6pvq.ffgz.tsg.suse.edu.cn/10.1038/s41422-022-00635-9,published online 10 March 2022 We found that the information in the original Supplementary Figs.S2–S4 was not fully displayed due to an error in the image upload.The correct images are shown below for better display.These corrections do not affect the description of the results or the conclusion of this work.No change of the original figure legends is needed.We apologize for the mistake.The original article has been corrected. | Ziqi Zhao Dan Zhang Fuqiang Yang Mingrui Xu Shaoli Zhao Taotao Pan Chuanyu Liu Yongjie Liu Qingfeng Wu Qiang Tu Ping Zhou Rong Li Jia Kang Lan Zhu Fei Gao Yaqing Wang Zhiheng Xu | 2023 | Cell Research2023,33,7: | 1 |
| 5 | SHED:Stem cells from human exfoliated deciduous teeth显示文摘 | Miura M Gronthos S Mingrui Zhao | 2003 | PNAS2003,100,10: | 1 |
| 6 | Oral administration of the herbal oligonucleotide XKC-sRNA-h3 prevents angiotensinⅡ-induced hypertension in mice显示文摘Hypertension has become a growing public health concern worldwide.In fact,hypertension is commonly associated with increased morbidity and mortality.Currently,oligonucleotide drugs have proven to be promising therapeutic agents for various diseases.In the present study,we aimed to demonstrate that a herbal small RNA(s RNA),XKC-sRNA-h3(B55710460,F221.I000082.B11),exhibits potent antihypertensive effects by targeting angiotensin-converting enzyme(ACE)in mice.When compared with captopril,oral administration of the sphingosine(d18:1)-XKC-s RNA-h3 bencaosome more effectively prevented angiotensin II-induced hypertensive cardiac damage and alleviated kidney injury in mice.Such findings indicated that XKC-sRNA-h3 may be a novel orally available ACE inhibitor type oligonucleotide drug for hypertension. | Kegong Tang Xiaona Wang Yu Zhao Xiaobei Li Zhenyu Jiang Song Mei Mingrui Chen Yiming Ma Xinyi Du Xiangyu Qiao Na Sun Jiaqi Liu Chengyu Jiang | 2023 | Science China(Life Sciences)2023,66,10: | 1 |
| 7 | Acetylation of ezrin regulates membrane–cytoskeleton interaction underlying CCL18-elicited cell migration显示文摘Ezrin,a membrane–cytoskeleton linker protein,plays an essential role in cell polarity establishment,cell migration,and division.Recent studies show that ezrin phosphorylation regulates breast cancer metastasis by promoting cancer cell survivor and promotes intrahepatic metastasis via cell migration.However,it was less characterized whether there are additional post-translational modifications and/or post-translational crosstalks on ezrin underlying context-dependent breast cancer cell migration and invasion.Here we show that ezrin is acetylated by p300/CBP-associated factor(PCAF)in breast cancer cells in response to CCL18 stimulation.Ezrin physically interacts with PCAF and is a cognate substrate of PCAF.The acetylation site of ezrin was mapped by mass spectrometric analyses,and dynamic acetylation of ezrin is essential for CCL18-induced breast cancer cell migration and invasion.Mechanistically,the acetylation reduced the lipid-binding activity of ezrin to ensure a robust and dynamic cycling between the plasma membrane and cytosol in response to CCL18 stimulation.Biochemical analyses show that ezrin acetylation prevents the phosphorylation of Thr567.Using atomic force microscopic measurements,our study revealed that acetylation of ezrin induced its unfolding into a dominant structure,which prevents ezrin phosphorylation at Thr567.Thus,these results present a previously undefined mechanism by which CCL18-elicited crosstalks between the acetylation and phosphorylation on ezrin control breast cancer cell migration and invasion.This suggests that targeting PCAF signaling could be a potential therapeutic strategy for combating hyperactive ezrin-driven cancer progression. | Xiaoyu Song Wanjuan Wang Haowei Wang Xiao Yuan Fengrui Yang Lingli Zhao McKay Mullen Shihao Du Najdat Zohbi Saravanakumar Muthusamy Yalei Cao Jiying Jiang Peng Xia Ping He Mingrui Ding Nerimah Emmett Mingming Ma Quan Wu Hadiyah-Nicole Green Xia Ding Dongmei Wang Fengsong Wang Xing Liu | 2020 | Journal of Molecular Cell Biology2020,12,6: | 1 |
| 8 | SHED: Stem cells from human exfoliated deciduous teeth显示文摘 | Miura M Gronthos S Mingrui Zhao | 2003 | PNAS2003,100,10: | 1 |
| 9 | Myosin 1D and the branched actin network control the condensation of p62 bodies显示文摘Biomolecular condensation driven by liquid-liquid phase separation(LLPS)is key to assembly of membraneless organelles in numerous crucial pathways.It is largely unknown how cellular structures or components spatiotemporally regulate LLPS and condensate formation.Here we reveal that cytoskeletal dynamics can control the condensation of p62 bodies comprising the autophagic adaptor p62/SQSTM1 and poly-ubiquitinated cargos.Branched actin networks are associated with p62 bodies and are required for their conden satio n.Myosi n 1D,a bran ched acti n-associated motor protein,drives coalesce nee of small nano scale p62 bodies into large micron-scale condensates along the branched actin network.Impairment of actin cytoskeletal networks compromises the condensation of p62 bodies and retards substrate degradation by autophagy in both cellular models and Myosin ID knockout mice.Coupling of LLPS scaffold to cytoskeleton systems may represent a general mechanism by which cells exert spatiotemporal control over phase condensation processes. | Xuezhao Feng Wanqing Du Mingrui Ding Wenkang Zhao Xirenayi Xirefu Meisheng Ma Yuhui Zhuang Xiaoyu Fu Jiangfeng Shen Jinpei Zhang Xiuying Lei Daxiao Sun Qing Xi Yiliyasi Aisa Qian Chenr Ying Li Wenjuan Wang Shanjin Huang Li Yu Pilong Li Na Mi | 2022 | Cell Research2022,32,7: | 1 |
| 10 | Holocene monsoon climate documented by oxygen and carbon isotopes from lake sediments and peat bogs in China: a review and synthesis显示文摘 | Jiawu Zhang Fahu Chen Jonathan A. Holmes Hui Li Xiaoyan Guo Junlan Wang Shuang Li Yanbin Lü Yan Zhao Mingrui Qiang | 2011 | Quaternary Science Reviews2011,,15: | 1 |
| 11 | Evolutionarily conservative and non-conservative regulatory networks during primate interneuron development revealed by single-cell RNA and ATAC sequencing显示文摘The differences in size and function between primate and rodent brains,and the association of disturbed excitatory/inhibitory balance with many neurodevelopmental disorders highlight the importance to study primate ganglionic eminences(GEs)development.Here we used single-cell RNA and ATAC sequencing to characterize the emergence of cell diversity in monkey and human GEs where most striatal and cortical interneurons are generated.We identified regional and temporal diversity among progenitor cells which give rise to a variety of interneurons.These cells are specified within the primate GEs by well conserved gene regulatory networks,similar to those identified in mice.However,we detected,in human,several novel regulatory pathways or factors involved in the specification and migration of interneurons.Importantly,comparison of progenitors between our human and published mouse GE datasets led to the discovery and confirmation of outer radial glial cells in GEs in human cortex.Our findings reveal both evolutionarily conservative and nonconservative regulatory networks in primate GEs,which may contribute to their larger brain sizes and more complex neural networks compared with mouse. | Ziqi Zhao Dan Zhang Fuqiang Yang Mingrui Xu Shaoli Zhao Taotao Pan Chuanyu Liu Yongjie Liu Qingfeng Wu Qiang Tu Ping Zhou Rong Li Jia Kang Lan Zhu Fei Gao Yaqing Wang Zhiheng Xu | 2022 | Cell Research2022,32,5: | 1 |
| 12 | The exceedingly strong two-dimensional ferromagnetism in biatomic layer SrRuO_(3)with a critical conduction transition显示文摘In recent years,few-layer or even monolayer ferromagnetic materials have drawn a great deal of attention due to the promising integration of two-dimensional(2D)magnets into next-generation spintronic devices.The SrRuO_(3)monolayer is a rare example of stable 2D magnetism under ambient conditions,but only weak ferromagnetism or antiferromagnetism has been found.The biatomic layer SrRuO_(3)as another environmentally inert 2D magnetic system has been paid less attention heretofore.Here we study both the bi-atomic layer and monolayer SrRuO_(3)in(SrRuO_(3))n/(SrTiO_(3))m(n=1,2)superlattices in which the SrTiO3 serves as a non-magnetic and insulating space layer.Although the monolayer exhibits arguably weak ferromagnetism,we find that the bi-atomic layer exhibits exceedingly strong ferromagnetism with a Tc of 125 K and a saturation magnetization of 1.2μB/Ru,demonstrated by both superconducting quantum interference device(SQUID)magnetometry and element-specific X-ray circular dichroism.Moreover,in the bi-atomic layer SrRuO_(3),we demonstrate that random fluctuations and orbital reconstructions inevitably occurring in the 2D limit are critical to the electrical transport,but are much less critical to the ferromagnetism.Our study demonstrates that the bi-atomic layer SrRuO_(3)is an exceedingly strong 2D ferromagnetic oxide which has great potentials for applications of ultracompact spintronic devices. | Jingxian Zhang Long Cheng Hui Cao Mingrui Bao Jiyin Zhao Xuguang Liu Aidi Zhao Yongseong Choi Hua Zhou Padraic Shafer Xiaofang Zhai | 2022 | Nano Research2022,15,8: | 0 |
| 13 | Influence of Assembly Parameters on Tensile Behavior of Hybrid CMC and Superalloy Bolted Joints by Progressive Damage Analysis显示文摘With the considerable applications of ceramic matrix composites(CMC) in aircraft engineering, the design of CMC bolted joint gains paramount attention because of its capacity to to improve load-bearing efficiency of aircraft key structure. In this work, a 3 D finite element model was established to predict tensile performance and failure modes of single-lap, single-bolt 2 D C/SiC composite, and superalloy joint, which considers the progressive damage behavior of 2 D woven C/SiC composites. On the basis of the developed progressive damage model, a parametric study was carried out to illustrate the effects of bolt preload and bolt-hole clearance on mechanical behaviors of the hybrid bolted joint. It was found that the increase in the value of bolt preload made the failure load grow first and then drop, and the optimum value of bolt preload 5.00 kN generated 56.47% rise in the initial failure load and 22.83% rise in the final failure load for the bolted joint in comparison with zero preload case. As the clearance increased from 0 to 2.00%, the initial and final failure loads respectively declined by 45.88% and 24.02% for 2.00% bolt-hole clearance relative to the neat-fit case. The loss in failure loads can be reduced to compressive stress concentration around the fastening hole-edge area, leading to the appearance of earlier damages by the introduction of increasing bolt hole clearance. | Chao Lv Feng Li Shuyuan Zhao Qian Sun Mingrui Li Xinyang Sun | 2021 | Journal of Harbin Institute of Technology(New Series)2021,28,3: | 0 |
| 14 | Highly sensitive,scalable,and rapid SARS-CoV-2 biosensor based on In_(2)O_(3)nanoribbon transistors and phosphatase显示文摘Developing convenient and accurate SARS-CoV-2 antigen test and serology test is crucial in curbing the global COVID-19 pandemic.In this work,we report an improved indium oxide(In2O3)nanoribbon field-effect transistor(FET)biosensor platform detecting both SARS-CoV-2 antigen and antibody.Our FET biosensors,which were fabricated using a scalable and cost-efficient lithography-free process utilizing shadow masks,consist of an In_(2)O_(3)channel and a newly developed stable enzyme reporter.During the biosensing process,the phosphatase enzymatic reaction generated pH change of the solution,which was then detected and converted to electrical signal by our In_(2)O_(3)FETs.The biosensors applied phosphatase as enzyme reporter,which has a much better stability than the widely used urease in FET based biosensors.As proof-of-principle studies,we demonstrate the detection of SARS-CoV-2 spike protein in both phosphate-buffered saline(PBS)buffer and universal transport medium(UTM)(limit of detection[LoD]:100 fg/mL).Following the SARS-CoV-2 antigen tests,we developed and characterized additional sensors aimed at SARS-CoV-2 IgG antibodies,which is important to trace past infection and vaccination.Our spike protein IgG antibody tests exhibit excellent detection limits in both PBS and human whole blood((LoD):1 pg/mL).Our biosensors display similar detection performance in different mediums,demonstrating that our biosensor approach is not limited by Debye screening from salts and can selectively detect biomarkers in physiological fluids.The newly selected enzyme for our platform performs much better performance and longer shelf life which will lead our biosensor platform to be capable for real clinical diagnosis usage. | Mingrui Chen Dingzhou Cui Zhiyuan Zhao Di Kang Zhen Li Shahad Albawardi Shahla Alsageer Faisal Alamri Abrar Alhazmi Moh.R.Amer Chongwu Zhou | 2022 | Nano Research2022,15,6: | 0 |
| 15 | An In-Situ MRI Method for Quantifying Temperature Changes during Crystal Hydrate Growths in Porous Medium显示文摘Given the complexity of the thermo-hydro-chemically coupled phase transition process of hydrates,real-time in-situ observations are required.Thermometry maps are particularly essential in analyzing the heat transfer process during the growth and dissociation of crystal hydrates.In this study,we present the temporally and spatially resolved thermometry of the formation of tetrahydrofuran hydrates based on the temperature dependence of the chemical shift of the water proton.Images of temperature changes were synchronously obtained using a 9.4 T^(1)H magnetic resonance imaging(MRI)system to predict the saturation level of the aqueous solution,phases of the solid hydrates,and the positive temperature anomaly of the exothermic reaction.It was observed that variations in the MRI signal decreased while the temperature rise differed significantly in space and time.The results predicted in this study could have significant implications in optimizing the phase transition process of gas hydrates. | ZHANG Lunxiang SUN Mingrui WANG Tian YANG Lei ZHANG Xiaotong ZHAO Jiafei SONG Yongchen | 2022 | Journal of Thermal Science2022,31,5: | 0 |
| 16 | Study of thermoelectric enhanced SERS and photocatalysis with ZnO-metal nanorod arrays显示文摘Herein,a thermoelectric induced surface-enhanced Raman scattering(SERS)substrate consisting of ZnO nanorod arrays and metal nanoparticles is proposed.The intensities of SERS signals are further enhanced by an order of magnitude and the limit of detection(LOD)for the molecules is reduced by at least one order of magnitude after the application of a thermoelectric potential.The enhancement mechanism is analyzed carefully and thoroughly based on the experimental and theoretical results,thus proving that the thermoelectric-induced enhancement of the SERS signals should be classified as a chemical contribution.Furthermore,it is proved that the electric regulation mechanism is universally applicable,and the fabricated substrate realizes enormous enhancements for various types of molecules,such as rhodamine 6G,methyl orange,crystal violet,amaranth,and biological molecules.Additionally,the proposed electric-induced SERS(E-SERS)substrate is also realized to monitor and manipulate the plasmon-activated redox reactions.We believe that this study can promote the course of the research on ESERS and plasmon-enhanced photocatalysts. | Baoqiang Du Jibing Tan Chang Ji Mingrui Shao Xiaofei Zhao Jing Yu Chao Zhang Chuansong Chen Hui Pan Baoyuan Man Zhen Li | 2023 | Nano Research2023,16,4: | 0 |
| 17 | Tracking Study at Circular Electron-positron Collider显示文摘The circular electron-positron collider(CEPC)is designed to study the property of Higgs bosonin depth.The baseline detector on CEPC uses time projection chamber(TPC)as main tracker.The raw data collected by detector should be reconstructed before studied by physicists.The reconstruction processes include the process from electronic signal to hit,the process from hit to track,and the process from track and calorimeter signal to particles.Reconstructing the tracks from the hits is an important and critical procedure in the reconstruction chain,which is called tracking. | ZHAO Mingrui RUAN Manqi HU Shouyang ZHOU Jing CHEN Lei LIU Wendi ZHI Yu LI Peiyu LI Xiaomei | 2018 | 中国原子能科学研究院年报2018,,1: | 0 |
| 18 | Development of PandaⅩⅢ Readout Module Test Platform显示文摘The goal of the PandaⅩⅢexperiment is to build the first Time Projection Chamber(TPC)of the 100kg class,high sensitivity and low-radio background gas in the world,which is capable to reconstruct the tracking of events by using TPC’s unique three-dimensional imaging principle and thereby study the non-neutrino double beta decay.China Institute of Atomic Energy is responsi- | HU Shouyang LI Xiaomei ZHOU Jing LI Xinglong CHEN Lei ZHI Yu LIU Wendi ZHAO Mingrui LI Peiyu | 2017 | Annual Report of China Institute of Atomic Energy2017,,1: | 0 |
| 19 | Study on Large Area GEM Foil显示文摘Recently,the gas electron multiplier(GEM)has become the main development direction of the new micro-pattern gas detectors,and has been developing rapidly in the world.The development of large area GEM foil,the core of the whole GEM detector,is highly demanded in the research field of micro-pattern detector in our country.At present,both the constructions | LI Xiaomei HU Shouyang ZHOU Jing LI Xinglong CHEN Lei ZHI Yu LIU Wendi ZHAO Mingrui LI Peiyu | 2017 | Annual Report of China Institute of Atomic Energy2017,,1: | 0 |
| 20 | Multi-Criteria Decision-Making for Power Grid Construction Project Investment Ranking Based on the Prospect Theory Improved by Rewarding Good and Punishing Bad Linear Transformation显示文摘Using the improved prospect theory with the linear transformations of rewarding good and punishing bad(RGPBIT),a new investment ranking model for power grid construction projects(PGCPs)is proposed.Given the uncertainty of each index value under the market environment,fuzzy numbers are used to describe qualitative indicators and interval numbers are used to describe quantitative ones.Taking into account decision-maker’s subjective risk attitudes,a multi-criteria decision-making(MCDM)method based on improved prospect theory is proposed.First,the[−1,1]RGPBIT operator is proposed to normalize the original data,to obtain the best andworst schemes of PGCPs.Furthermore,the correlation coefficients between interval/fuzzy numbers and the best/worst schemes are defined and introduced to the prospect theory to improve its value function and loss function,and the positive and negative prospect value matrices of the project are obtained.Then,the optimization model with the maximum comprehensive prospect value is constructed,the optimal attribute weight is determined,and the PGCPs are ranked accordingly.Taking four PGCPs of the IEEERTS-79 node system as examples,an illustration of the feasibility and effectiveness of the proposed method is provided. | Shun Ma Na Yu Xiuna Wang Shiyan Mei Mingrui Zhao Xiaoyu Han | 2023 | Energy Engineering2023,120,10: | 0 |