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| 1 | A 600-year flood history in the Yangtze River drainage:Comparison between a subaqueous delta and historical records显示文摘Based on grain size analysis and high-resolution elemental scanning of core YD0901,taken from the subaqueous Yangtze River delta,a 600-year flood history was reconstructed for the Yangtze River drainage system.Zr/Rb ratios were chosen as a proxy for Yangtze River floods.Zr resides mainly in the coarse-grained minerals,and Rb is found in the fine-grained minerals.When floods occur,the discharge of the Yangtze River increases,which carries more coarse-grained minerals into the East China Sea.Therefore,deposition of coarse-grained minerals significantly increases relative to fine-grained minerals on the subaqueous delta,and subsequently the Zr/Rb ratios also increase.The higher the Zr/Rb peaks,the greater number of coarse particles deposited by saltation processes.Zr/Rb peaks correlate very well with historical records for Yangtze River floods.Especially at about AD 1870,the Zr/Rb ratio reached a maximum value over the last 600 years,which is consistent with 'the extreme flood event' in the upper and middle reaches of the Yangtze River in AD 1870,as indicated in the historical records.Results show that floods have occurred at a relatively high frequency over the last 600 years,which is consistent with historical records when,during the Ming-Qing Dynasty,floods occurred once every 4 years.In addition,spectral analysis of the Zr/Rb ratio showed that there is close link between the Yangtze River floods and ENSO intensity. | WANG MinJie ZHENG HongBo XIE Xin FAN DaiDu YANG ShouYe ZHAO QuanHong WANG Ke | 2011 | Chinese Science Bulletin2011，56，2： | 9 |
| 2 | Genomic insights into the fast growth of paulownias and the formation of Paulownia witches' broom显示文摘Paulownias are among the fastest growing trees in the world,but they often suffer tremendous loss of wood production due to infection by Paulownia witches'broom(PaWB)phytoplasmas.In this study,we have sequenced and assembled a high-quality nuclear genome of Paulownia fortunei,a commonly cultivated paulownia species.The assembled genome of P.fortunei is 511.6 Mb in size,with 93.2%of its sequences anchored to 20 pseudo-chromosomes,and it contains 31985 protein-coding genes.Phylogenomic analyses show that the family Paulowniaceae is sister to a clade composed of Phrymaceae and Orobanchaceae.Higher photosynthetic efficiency is achieved by integrating C3 photosynthesis and the crassulacean acid metabolism pathway,which may contribute to the extremely fast growth habit of paulownia trees.Comparative transcriptome analyses reveal modules related to cambial growth and development,photosynthesis,and defense responses.Additional genome sequencing of PaWB phytoplasma,combined with functional analyses,indicates that the effector PaWB-SAP54 interacts directly with Paulownia PfSPLa,which in turn causes the degradation of PfSPLa by the ubiquitin-mediated pathway and leads to the formation of witches'broom.Taken together,these results provide significant insights into the biology of paulownias and the regulatory mechanism for the formation of PaWB. | Yabing Cao Guiling Sun Xiaoqiao Zhai Pingluo Xu Liming Ma Minjie Deng Zhenli Zhao Haibo Yang Yanpeng Dong Zhonghai Shang Yujie Lv Lijun Yan Haifang Liu Xibing Cao Bingbing Li Zhe Wang Xiaogai Zhao Haiyan Yu Fan Wang Wen Ma Jinling Huang Guoqiang Fan | 2021 | Molecular Plant2021，14，10： | 7 |
| 3 | Virus-induced gene silencing(VIGS)in Chinese narcissus and its use in functional analysis of NtMYB3显示文摘Virus-induced gene silencing(VIGS)is a natural defense mechanism of plants,which can cause sequence-specific degradation of viral RNA and is often used for studying the functional genome.At present,the VIGS system mediated by Tobacco rattle virus(TRV)has been successfully established in many plant species.However,the VIGS system in Chinese narcissus had not been reported yet.In this paper,the first use of the TRV-VIGS system in Chinese narcissus is described in detail.By injecting pTRV2-GFP into narcissus leaves,we confirmed that TRV could infect narcissus and move in narcissus plants.After the inoculation of pTRV2-Nt PDS by two methods,phenomena such as photo-bleaching appeared in narcissus leaves and qRT-PCR results proved that PDS gene of narcissus was successfully silenced.Besides,pTRV2-NtMYB3 was inoculated into basal plates of narcissus to study the function of NtMYB3;the results showed that NtMYB3 is an inhibitor of flavonoids biosynthesis,which can increase the content of proanthocyanidins in basal plates of narcissus by repressing the expression level of NtFLS.These results indicate that the TRV-VIGS system has been successfully established in Chinese narcissus and successfully applied to the functional study of NtMYB3. | Ping Zhou Jiayu Peng Minjie Zeng Lixuan Wu Yuxin Fan Lihui Zeng | 2021 | Horticultural Plant Journal2021，7，6： | 4 |
| 4 | A male-ABCD algorithm for hepatocellular carcinoma risk prediction in HBs Ag carriers显示文摘Objective: Hepatocellular carcinoma(HCC) development among hepatitis B surface antigen(HBs Ag) carriers shows gender disparity, influenced by underlying liver diseases that display variations in laboratory tests. We aimed to construct a risk-stratified HCC prediction model for HBs Ag-positive male adults.Methods: HBs Ag-positive males of 35-69 years old(N=6,153) were included from a multi-center populationbased liver cancer screening study. Randomly, three centers were set as training, the other three centers as validation. Within 2 years since initiation, we administrated at least two rounds of HCC screening using Bultrasonography and α-fetoprotein(AFP). We used logistic regression models to determine potential risk factors,built and examined the operating characteristics of a point-based algorithm for HCC risk prediction.Results: With 2 years of follow-up, 302 HCC cases were diagnosed. A male-ABCD algorithm was constructed including participant's age, blood levels of GGT(γ-glutamyl-transpeptidase), counts of platelets, white cells,concentration of DCP(des-γ-carboxy-prothrombin) and AFP, with scores ranging from 0 to 18.3. The area under receiver operating characteristic was 0.91(0.90-0.93), larger than existing models. At 1.5 points of risk score,26.10% of the participants in training cohort and 14.94% in validation cohort were recognized at low risk, with sensitivity of identifying HCC remained 100%. At 2.5 points, 46.51% of the participants in training cohort and 33.68% in validation cohort were recognized at low risk with 99.06% and 97.78% of sensitivity, respectively. At 4.5 points, only 20.86% of participants in training cohort and 23.73% in validation cohort were recognized at high risk,with positive prediction value of 22.85% and 12.35%, respectively.Conclusions: Male-ABCD algorithm identified individual's risk for HCC occurrence within short term for their HCC precision surveillance. | Yuting Wang Minjie Wang He Li Kun Chen Hongmei Zeng Xinyu Bi Zheng Zhu Yuchen Jiao Yong Wang Jian Zhu Hui Zhao Xiang Liu Chunyun Dai Chunsun Fan Can Zhao Deyin Guo Hong Zhao Jianguo Zhou Dongmei Wang Zhiyuan Wu Xinming Zhao Wei Cui Xuehong Zhang Jianqiang Cai Wanqing Chen Chunfeng Qu | 2021 | Chinese Journal of Cancer Research2021，33，3： | 3 |
| 5 | Different self-assembly behaviors of mono-modified β-cyclodextrin substituted by benzoic acid derivatives显示文摘The mono-modified β-cyclodextrin derivative,6-O-(4-aminobenzoyl)-β-cyclodextrin(1) ,was synthesized and characterized. We compared its self-assembling behavior with structurally related β-cyclodextrin derivative,6-O-(4-hydroxybenzoyl)-βcyclodextrin(2) ,in aqueous solution and in the solid state using NMR spectroscopy and single crystal X-ray structure analysis. The two complexes displayed different self-assembling behaviors.Complex 1 formed a head-to-tail helical columnar superstructure in which the substituent group penetrated deeply into the hydrophobic cavity of the adjacent β-cyclodextrin from the second side and aligned along the screw axis,whereas 2 exhibited a channel superstructure with a tail-to-tail dimer as the repeating motif.Further NMR studies in aqueous solution supported the result of the solid state.The influence of substituent groups on the self-assembly behavior was examined in mono-modified β-cyclodextrins by means of substituting an amino group for a hydroxyl group,which indicates that the weak intermolecular interaction is a critical factor in determining the self-assembling behavior. | Zhi Fan MinJie Guo Bin Dong ChunHua Diao ZuoLiang Jing Xin Chen | 2010 | Science China Chemistry2010，53，5： | 2 |
| 6 | An Innovative Approach for the Short-term Traffic Flow Prediction显示文摘Traffic flow prediction plays an important role in intelligent transportation applications,such as traffic control,navigation,path planning,etc.,which are closely related to people's daily life.In the last twenty years,many traffic flow prediction approaches have been proposed.However,some of these approaches use the regression based mechanisms,which cannot achieve accurate short-term traffic flow predication.While,other approaches use the neural network based mechanisms,which cannot work well with limited amount of training data.To this end,a light weight tensor-based traffic flow prediction approach is proposed,which can achieve efficient and accurate short-term traffic flow prediction with continuous traffic flow data in a limited period of time.In the proposed approach,first,a tensor-based traffic flow model is proposed to establish the multi-dimensional relationships for traffic flow values in continuous time intervals.Then,a CANDECOMP/PARAFAC decomposition based algorithm is employed to complete the missing values in the constructed tensor.Finally,the completed tensor can be directly used to achieve efficient and accurate traffic flow prediction.The experiments on the real dataset indicate that the proposed approach outperforms many current approaches on traffic flow prediction with limited amount of traffic flow data. | Xing Su Minghui Fan Minjie Zhang Yi Liang Limin Guo | 2021 | Journal of Systems Science and Systems Engineering2021，30，5： | 1 |
| 7 | Advanced Materials Research显示文摘 | Fan Jiangkun Kou Hongchao Lai Minjie | 2012 | 538:9452012，538，： | 1 |
| 8 | Microwave-assisted extraction of effective constituents from a Chinese herbal medicine Radix puerariae显示文摘 | Zhenku Guo Qinhan Jin Guoqiang Fan Yuping Duan Chen Qin Minjie Wen | 2001 | Analytica Chimica Acta2001，，1： | 1 |
| 9 | Advances in friction of aluminium alloy deep drawing显示文摘Broad use of lightweight aluminium alloy parts in automobile manufacturing,aerospace,electronic communication,and rail transit is mainly formed through deep drawing process.Deep drawing friction is a key boundary condition for controlling the forming quality of aluminium alloy parts.However,due to the oxidation and adhesion tendency of aluminium alloys,the tribological situations of aluminium alloy deep drawing(AADD)system is more complicated than those of traditional deep drawing of steel sheets.Therefore,the study of AADD friction is essential for manufacturing high-performance aluminium alloy parts.Herein,aiming to provide a valuable reference for researchers in related fields,a comprehensive review of AADD friction is provided,including friction mechanism,influencing factors,friction measurement,friction model,friction simulation,and lubrication-free friction control.Finally,a brief conclusion and several current challenges were discussed. | Yiren GAO Hongxia LI Danyang ZHAO Minjie WANG Xiaobo FAN | 2024 | Friction2024，12，3： | 0 |
| 10 | Piezoelectric Properties of Three Types of PVDF and ZnO Nanofibrous Composites显示文摘Piezoelectric materials are highly desirable for wearable electronics and energy harvesting.Piezoelectric PVDF/ZnO com-posite nanofibers are particularly desirable for their nontoxicity,breathability,and flexibility.Here,we investigated three methods of fabricating PVDF and ZnO composite nanofibers aimed at optimum piezoelectric responses.It was found,(1)adding ZnO nanorod as fillers within the PVDF nanofiber did not improve piezoelectric response due to the fact that the process made the material more dielectric;(2)ZnO nanorods on the PVDF surface increased the power output due to the combined effects of piezoelectricity of ZnO nanorods as well as the triboelectric response of the increased surface roughness;(3)electrospraying pre-synthesized ZnO nanorods on PVDF nanofibers resulted in the highest piezoelectric response due to the combined effect of the greater piezoelectricity of aligned ZnO nanorods and PVDF nanofibers,and larger triboelectric response from increased surface roughness. | Minji Kim Jintu Fan | 2021 | Advanced Fiber Materials2021，3，3： | 0 |
| 11 | Preparation of HNS microspheres by rapid membrane emulsification显示文摘In order to improve the dispersibility and loading efficiency of 2,2',4,4',6,6'-hexanitrostilbene(HNS),HNS microspheres were prepared by rapid membrane emulsification method with nitrocellulose(NC)as binder.The effects of NC solution concentration,stirring speed and polyvinyl alcohol(PVA)solution concentration on microspheres were investigated.It was characterized by scanning electron microscope(SEM),X-ray diffractometer(XRD),differential thermal analysis(DTA)and angle of repose analyzer.The results show that the HNS microspheres prepared with 5 wt%NC solution concentration,stirring speed of 100 rpm and 2 wt%PVA solution concentration have better regular morphology,higher sphericity,unchanged crystalline shape,increased activation energy and significantly improved dispersibility compared with the refined HNS.Rapid membrane emulsification has a series of advantages such as green,low cost and easy scale up,which provides a better way to prepare microspheres of energy materials. | Hongbiao Huo Baoyun Ye Yuhuai Shi Chenhe Feng Jiechao Wang Minjie Li Jiake Fan Lianqiang Li Jingyu Wang Chongwei An | 2023 | Particuology2023，，8： | 0 |
| 12 | On-off-on fluorescence detection for biomolecules by a fluorescent cage through host-guest complexation in water显示文摘Detection of nucleoside derivatives has paramount importance because they are the essential biomolec-ular units for all life.Herein,we report a host-guest approach by using a fluorescent tetraphenylethene-based octacationic cage as host and 8-hydroxypyrene-1,3,6-trisulfonic acid trisodium salt(HPTS)as guest and fluorescent indicator to form non-fluorescent 1:1:1 host-(endo-exo)guest complex in water.This new host-(endo-exo)guest complex can be successfully used for detecting nucleosides(e.g.,ATP and GTP),DNA(e.g.,sm-DNA),and antibiotics(e.g.,Penicillin G)with off-on fluorescence response via a competitive host-guest exchange with HPTS as exo-guest in water.Furthermore,this on-off-on fluorescent host-guest com-plex is also used for cell imaging based on ATP concentration in HeLa cells.Therefore,this study not only provides insight into the construction of a supramolecular probe with on-off-on fluorescence via host-guest complexation and exchange in solution,but also realizes a universal method for detecting and monitoring biomolecules. | Honghong Duan Fan Cao Minjie Zhang Meng Gao Liping Cao | 2022 | Chinese Chemical Letters2022，33，5： | 0 |
| 13 | Management and operation of extra-large Fangcang hospitals:experience and lessons from containing the highly contagious SARS-CoV-2 Omicron in Shanghai,China显示文摘Introduction Omicron is more contagious and stealthier than the previous strains.The basic reproduction number of Omicron is around 8–12,whereas that of the previous mainstream strain Delta is only 5–8[1].Omicron’s symptoms are relatively mild[2]compared with Delta’s symptoms;however,Omicron’s transmission ability is very strong,and its risk to children and the elderly remains high[3].In addition,the vaccine’s preventive effect on Omicron has weakened.Therefore,Omicron can easily cause a rapid outbreak in a city.The population density of megacities and the limited public health resources further exacerbate the difficulty of Omicron prevention and control. | Yun Xian Chenhao Yu Minjie Chen Lin Zhang Xinyi Zheng Shijian Li Erzhen Chen Zhongwan Chen Weihua Chen Chaoying Wang Qingrong Xu Tao Han Weidong Ye Wenyi Xu Xu Zhuang Yu Zheng Min Chen Jun Qin Yu Feng Shun Wei Yiling Fan Zhiruo Zhang Junhua Zheng | 2023 | Frontiers of Medicine2023，17，1： | 0 |
| 14 | Application of three-dimensional printed navigation templates to correct lower limb deformities in children by the guided growth technique显示文摘Objective Currently,individualized navigation templates are rarely applied in pediatric orthopedic surgery.This study aimed to explore the potential of navigation templates obtained using computer-aided design and three-dimensional(3D)printing to correct lower limb deformities in children by the guided growth technique.Methods We prospectively studied 45 children with leg length discrepancy(LLD)or lower limb angular deformities,who underwent guided growth surgery involving 8-plate.In total,21 and 24 children were included in the navigation template(group A)group and in the traditional surgery(group B)group,respectively.Mimics software was used for designing and printing navigation templates.The operation time,X-ray radiation exposure,damage to cartilage,and postoperative complications were recorded.Results The mean operation time in groups A and B were 20.78 and 28.39 min,respectively,and the difference was statistically significant.Compared with group B,the intraoperative exposure of X-rays in group A was reduced by 25%on average.After 9-24 months of follow-up,the deformities were corrected in both groups.No significant differences in the treatment effect were noted between the groups,and no complications occurred.Conclusions Using the individualized navigation template in the guided growth technique made the surgical procedure convenient and simple to perform.In addition,the operation time and intraoperative exposure to X-rays were reduced.We consider that 3D printed navigation templates can facilitate the accurate completion of corrective surgeries for lower limb deformities in children,which is worthy of promotion and application. | Minjie Fan Yinming Wang Haotian Pang Yiwei Wang Peng Xu Yue Lou Pengfei Zheng Kai Tang | 2022 | World Journal of Pediatric Surgery2022，5，3： | 0 |
| 15 | 人工智能白内障协同管理的通用平台显示文摘目的:建立和验证一个涉及多级临床场景的白内障协作通用的人工智能(artificial intelligence,AI)管理平台,探索基于AI的医疗转诊模式,以提高协作效率和资源覆盖率。方法:训练和验证的数据集来自中国AI医学联盟,涵盖多级医疗机构和采集模式。使用三步策略对数据集进行标记:1)识别采集模式;2)白内障诊断包括正常晶体眼、白内障眼或白内障术后眼;3)从病因和严重程度检测需转诊的白内障患者。此外,将白内障AI系统与真实世界中的居家自我监测、初级医疗保健机构和专科医院等多级转诊模式相结合。结果:通用AI平台和多级协作模式在三步任务中表现出可靠的诊断性能:1)识别采集模式的受试者操作特征(receiver operating characteristic curve,ROC)曲线下面积(area under the curve,AUC)为99.28%~99.71%);2)白内障诊断对正常晶体眼、白内障或术后眼,在散瞳-裂隙灯模式下的AUC分别为99.82%、99.96%和99.93%,其他采集模式的AUC均>99%;3)需转诊白内障的检测(在所有测试中AUC>91%)。在真实世界的三级转诊模式中,该系统建议30.3%的人转诊,与传统模式相比,眼科医生与人群服务比率大幅提高了10.2倍。结论:通用AI平台和多级协作模式显示了准确的白内障诊断性能和有效的白内障转诊服务。建议AI的医疗转诊模式扩展应用到其他常见疾病和资源密集型情景当中。 | WU Xiaohang HUANG Yelin LIU Zhenzhen LAI Weiyi LONG Erping ZHANG Kai JIANG Jiewei LIN Duoru CHEN Kexin YU Tongyong WU Dongxuan LI Cong CHEN Yanyi ZOU Minjie CHEN Chuan ZHU Yi GUO Chong ZHANG Xiayin WANG Ruixin YANG Yahan XIANG Yifan CHEN Lijian LIU Congxin XIONG Jianhao GE Zongyuan WANG Dingding XU Guihua DU Shaolin XIAO Chi WU Jianghao ZHU Ke NIE Danyao XU Fan LV Jian CHEN Weirong LIU Yizhi 林浩添 无 王厚硕(审校) 罗明杰(审校) | 2023 | 眼科学报2023，38，10： | 0 |
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