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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | The in vivo and in vitro effects of chicken interferon on infectious bursal disease virus and New castle disease virus infection 显示文摘 | Mo C W Cao Y C Lim B L | 2001 | Avian Diseases2001，5，： | 1 |
| 3 | Unbiased conver- ted measurements for tracking 显示文摘 | MO L B SONG X Q ZHOU Y Y | 1998 | IEEE Transactions on AES1998，34，3： | 1 |
| 4 | The in vivo and in vitro effects of chicken interferon a on infectious bursal disease virus and Newcastle disease virus infection显示文摘 | Mo C W Cao Y C Lim B L | 2001 | Avian Diseases2001，45，2： | 1 |
| 5 | The in vivo and in vitro effects of chicken interferon α on infectious bursal disease virus and Newcastle disease virus infection显示文摘 | Mo C W Cao Y C Lim B L | 2001 | Avian Diseases2001，45，： | 1 |
| 6 | EseD, a putative T3SS translocon component of Edwardsiella tarda, contributes to virulence in fish and is a candidate for vaccine development 显示文摘 | Wang B Mo Z L Xiao P | 2010 | Mar Biotechnol (NY)2010，12，6： | 1 |
| 7 | Facile Synthesis of Ternary Boron Carbonitride Nanotubes显示文摘 | Luo L J Mo L B Tong Z F | 2009 | Nanoscale Res Lett2009，4，： | 1 |
| 8 | Complete genomesequence of two Chinese virulent avian coronavirus in-fectious bronchitis virus variants 显示文摘 | Mo M L Huang B C Wei P | 2012 | Journal of Virol-ogy2012，86，10： | 1 |
| 9 | The in vivo and in vitro effects of chicken interferon α on infectious bursal disease virus and Newcastle disease virus infection显示文摘 | Mo C W Can Y C Lim B L | 2001 | Avian Diseases2001，45，： | 1 |
| 10 | F l u i d –solid interaction simulation of flow and stress pattern inthoracoabdominal aneurysms:a patient-specific study显示文摘 | B o r g h i A Wo o d NB Mo h i a d d i n RH e t a l | 2008 | JFluids Struct2008，24，2： | 1 |
| 11 | Facile synthesis of ternary boron carbonitride nanotubes显示文摘 | Luo L J Mo L B Tong Z F | 2009 | Nanoscale Res Lett2009，4，8： | 1 |
| 12 | Finding the most vital arcs in a network显示文摘 | Ball Mo Golden B L Vohra R V | 1989 | Operation Research Letters1989，8，2： | 1 |
| 13 | Systemic antibiotic prophylaxis after gastro intestinal hemorrhage in cirrhotic patients with high risk of infection 显示文摘 | PAUWELS A MO STEFA KARA N DEBENES B et a l | 1996 | Hepatology1996，24，4： | 1 |
| 14 | Linking immune-mediated arterial inflammation and cholesterol-induced atherosclerosis in a transgenic mouse model显示文摘 | Ludewig B Freigang S Jaggi M Kurrer MO Pei YC Vik L | 2000 | Proc Natl Acad Sci USA2000，97，12： | 1 |
| 15 | ANP/NPRA signaling preferen tially mediates Th2 responses in favor of pathological processes during the course of acute allergic asthma显示文摘 | Ma L Zeng J Mo B | 2015 | Int J Clin Exp Med2015，8，4： | 1 |
| 16 | Photocatalytic oxidation of heptane in the gas - phase over TiO2显示文摘 | Mo S D Lin L B Lin D L | 1994 | J Phys Chem Solids1994，55，： | 1 |
| 17 | Two-sided micro- matching with technical progress 显示文摘 | Chen B L Mo J P Wang P | 2012 | Economic Theory2012，50，2： | 1 |
| 18 | Fresh and hardened properties of seE-consolidating fiber reinforced concrete 显示文摘 | Dhonde H B Mo Y L Hsu T T C | 2007 | ACI Materials Journal2007，104，5： | 1 |
| 19 | Self - sensing of carbon nanofiber concrete columns subjected to reversed cyclic loading 显示文摘 | R N Howser H B Dhonde Y L Mo | 2011 | Smart Materials and Strncturtes2011，20，08： | 1 |
| 20 | Biocompatibility of bioresorable poly(L-lactic acid)composite scaffolds obtained by supercritical gas foaming with human fetal bone cells显示文摘 | Montjovent MO Mathieu L Hinz B | 2005 | Tissue Eng2005，11，1112： | 1 |
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