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| 1 | Integrated assessment of river health based on water quality, aquatic life and physical habitat显示文摘The health conditions of Liao River were assessed using 25 sampling sites in April 2005, with water quality index, biotic index and physical habitat quality index. Based on the method of cluster analysis (CA) for water quality indices, it revealed that heavily polluted sites of Liao River are located at estuary and mainstream. The aquatic species surveyed were attached algae and benthic invertebrates. The result showed that the diversity and biomass of attached algae and benthic index of biotic integrity (B-IBI) were degrading as the chemical and physical quality of water bodies deteriorating. Physiochemical parameters, BOD5, CODCr, TN, TP, NH3-N, DO, petroleum hydrocarbon and conductivity, were statistically analyzed with principal component analysis and correlation analysis. The statistical results were incorporated into the integrated assessing water quality index, combining fecal coliform count, attached algae diversity, B-IBI and physical habitat quality score. A comprehensive integrated assessing system of river ecological health was established. Based on the systimetic assessment, the assessed sites are categorized into 9 'healthy' and 'sub-healthy' sites and 8 'sub-sick' and 'sick' sites. | MENG Wei ZHANG Nan ZHANG Yuan ZHENG Binghui | 2009 | Journal of Environmental Sciences2009，21，8： | 29 |
| 2 | L-3-n-butylphthalide protects against vascular dementia via activation of the Akt kinase pathway显示文摘As a neuroprotective drug for the treatment of ischemic stroke, 3-n-butylphthalide, a celery seed extract, has been approved by the State Food and Drug Administration of China as a clinical therapeutic drug for ischemic stroke patients. L-3-n-butylphthalide possesses significant efficacy in the treatment of acute ischemic stroke. The activated Akt kinase pathway can prevent the death of nerve cells and exhibit neuroprotective effects in the brain after stroke. This study provides the hypothesis that l-3-n-butylphthalide has a certain therapeutic effect on vascular dementia, and its mechanism depends on the activation of the Akt kinase pathway. A vascular dementia mouse model was established by cerebral repetitive ischemia/reperfusion, and intragastrically administered l-3-n-butylphthalide daily for 28 consecutive days after ischemia/reperfusion, or 7 consecutive days before ischemia/reperfusion. The Morris water maze test showed significant impairment of spatial learning and memory at 4 weeks after operation, but intragastric administration of l-3-n-butylphthalide, especially pretreatment with l-3-n-butylphthalide, significantly reversed these changes. Thionine staining and western blot analylsis showed that preventive and therapeutic application of l-3-n-butylphthalide can reduce loss of pyramidal neurons in the hippocampal CA1 region and alleviate nerve damage in mice with vascular demen-tia. In addition, phosphorylated Akt expression in hippocampal tissue increased significantly after l-3-n-butylphthalide treatment. Experimental findings demonstrate that l-3-n-butylphthalide has preventive and therapeutic effects on vascular dementia, and its mechanism may be mediated by upregulation of phosphorylated Akt in the hippocampus. | Yaping Huai Yanhong Dong Jing Xu Nan Meng Chunfeng Song Wenbin Li Peiyuan Lv | 2013 | Neural Regeneration Research2013，8，19： | 17 |
| 3 | COL4A3 mutations cause focal segmenta glomerulosclerosis显示文摘 | Jingyuan Xie Xiaoxi Wu Hong Ren Weiming Wang Zhaohui Wang Xiaoxia Pan Xu Hao Jun Tong Jun Ma Zhibin Ye Guoyu Meng Yufei Zhu Krzysztof Kiryluk Xiangyin Kong Landian Hu Nan Chen | 2014 | Journal of Molecular Cell Biology2014，8，6： | 15 |
| 4 | Dispersion stabilization of antimony-doped tin oxide(ATO)nanoparticles used for energy-efficient glass coating显示文摘Nano-antimony-doped tin oxide(ATO) was synthesized using the sol-gel method.A colloidal dispersion of ATO nanoparticles in distilled water was achieved using a milling process in which different dispersants were studied.In this paper,different factors that affect the stability of ATO nanoparticles were discussed,such as zeta potential,dispersant,and pH value.Sodium polyphosphate was a suitable dispersant for stabilizing ATO nanoparticles in distilled water.A stable dispersion of ATO nanoparticles in distilled water was prepared.The stable dispersion of ATO nanoparticles was used to prepare nano-thermal insulation glass paint to block near-infrared rays of sunlight. | Ning Li Qinglin Meng Nan Zhang | 2014 | Particuology2014，12，6： | 11 |
| 5 | Effect of Pulsed Radiofrequency on Rat Sciatic Nerve Chronic Constriction Injury: A Preliminary Study显示文摘 | Duo-Yi Li Lan Meng Nan Ji Fang Luo | 2015 | Chinese Medical Journal2015，，4： | 9 |
| 6 | Fast removal of heavy metal ions and phytic acids from water using new modified chelating fiber显示文摘到聚乙烯乙二醇 terephthalate (宠物) 上,纤维由 benzoy 过氧化物(BPO ) 开始了的丙烯酸的酸(AA ) 的接枝 copolymerization 在异构的媒介被执行。而且, grafted 宠物纤维(PET-AA ) 的修正被与 dimethylamine 通过反应把 carboxyl 组变成 acylamino 组做。修改 chelating 纤维(NDWJN1 ) 用基本分析, SEM 和英尺红外光谱学被描绘。吸附运动曲线显示 NDWJN1 能快有效地把重金属离子和 phytic 酸从水移开。而且,运动研究显示了的批离子吸附了到 NDWJN1 的那重金属能被伪 first-order 和 pseudo-second-order 吸附方程适合很好,但是 intra 粒子散开在 phytic 酸的吸附起了一个主导的作用。 | Li Xu Jin Nan Wang Ying Meng Ai Min Li | 2012 | Chinese Chemical Letters2012，23，1： | 8 |
| 7 | Successful robotic radical resection of hepatic echinococcosis located in posterosuperior liver segments显示文摘BACKGROUND Radical resection is an important treatment method for hepatic echinococcosis.The posterosuperior segments of the liver remain the most challenging region for laparoscopic or robotic hepatectomy.AIM To demonstrate the safety and preliminary experience of robotic radical resection of cystic and alveolar echinococcosis in posterosuperior liver segments.METHODS A retrospective analysis was conducted on the clinical data of 5 patients with a median age of 37 years(21-56 years)with cystic and alveolar echinococcosis in difficult liver lesions admitted to two centers from September to December 2019.The surgical methods included total pericystectomy,segmental hepatectomy,or hemihepatectomy.RESULTS Among the 5 patients,4 presented with cystic echinococcosis and 1 presented with alveolar echinococcosis,all of whom underwent robotic radical operation successfully without conversion to laparotomy.Total caudate lobectomy was performed in 2 cases,hepatectomy of segment Ⅶ in 1 case,total pericystectomy of segment Ⅷ in 1 case,and right hemihepatectomy in 1 case.Operation time was 225 min(175-300 min);blood loss was 100 mL(50-600 mL);and postoperative hospital stay duration was 10 d(5-19 d).The Clavien-Dindo complication grade was Ⅰ in 4 cases and Ⅱ in 1 case.No recurrence of echinococcosis was found in any patient at the 3 mo of follow-up.CONCLUSION Robotic radical surgery for cystic and selected alveolar echinococcosis in posterosuperior liver segments is safe and feasible. | Zhi-Ming Zhao Zhu-Zeng Yin Yuan Meng Nan Jiang Zhi-Gang Ma Li-Chao Pan Xiang-Long Tan Xiong Chen Rong Liu | 2020 | World Journal of Gastroenterology2020，26，21： | 7 |
| 8 | Effects of long-term tea polyphenols consumption on hepatic microsomal drug-metabolizing enzymes and liver function in Wistar rats显示文摘AIM: To investigate the effects of long-term tea polyphenols (TPs) consumption on hepatic microsomal drug-metabolizing enzymes and liver function in rats.METHODS: TPs were administered intragastrically to rats at the doses of 833 mg.kg-1.d-1 (n=20) and 83.3 mg.kg-1@d-1 (n=20) respectively for six months. Controlled group (n=20)was given same volume of saline solution. Then the contents of cytochrome P450, bS, enzyme activities of aminopyrine N-demethylase (ADM), glutathione S-trasferase (GST) and the biochemical liver function of serum were determined.RESULTS: The contents of cytochrome P450 and b5 in the livers of male rats in high dose groups (respectively 2.66±0.55,10.43±2.78 nmol.mg MS pro-1) were significantly increased compared with the control group (1.08±1.04, 5.51±2.98nmol.mg MS pro-1; P<0.01, respectively). The enzymatic activities of ADM in the livers of female rats in high dose groups (0.91±0.08 mmol@mg MS pro-1min-1) were increased compared with the control group (0.82±0.08 mmol.mg MS pro-1.min-1; P<0.05). The GST activity was unchanged in all treated groups, and the function of liver was not obviously changed.CONCLUSION: The antidotal capability of rats' livers can be significantly improved after long-term consumption of TPs.There are differences in changes of drug-metabolizing enzymes between the sexes induced by TPs and normal condition. | Tao-Tao Liu Department of Pharmacy,First Affiliated Hospital,Guangxi Medical University,Nanning 530021,Guangxi Zhuang Autonomous Region,China Ning-Sheng Liang Yan Li Fan Yang Yi Lu Zi-Qing Meng Li-Sheng Zhang Department of Pharmacology,Guangxi Cancer Institute,Nanning 530021,Guangxi Zhuang Autonomous Region,China | 2003 | World Journal of Gastroenterology2003，9，12： | 7 |
| 9 | Recent Progress and Development in Extrusion of Rare Earth Free Mg Alloys: A Review显示文摘Mg and its alloys are the lightest structural metals available and are extremely attractive for applications as lightweight components, particularly in the automobile, electronic, and aerospace industries. The global market for wrought Mg alloys has steadily expanded over the past decade. And numerous studies have been carried out to meet this increasing demand of high-performance Mg alloys. However, Mg extrusion alloys have had a very limited usage so far. To overcome existing industrial challenges, one desirable approach is the development of low-cost rare earth(RE) free Mg extrusion alloys with superior mechanical properties. This review will introduce the recent research highlights in the extrusion of Mg alloys, specifi cally focusing on low-cost RE-free Mg alloy. The results from both the literature and our previous study are summarized and critically reviewed. Several aspects of RE-free Mg extrusion alloys are described in detail:(1) novel alloying designs including Mg–Al-, Mg–Zn-, Mg–Ca-, Mg–Sn-, and Mg–Bi-based alloys,(2) advanced extrusion techniques, and(3) extrusion-related severe plastic deformation(SPD) processing. Accordingly, considering the large gap in mechanical properties between the current RE-free Mg alloys and high-performance aluminum alloys, new alloy design, processing route control, and recommendations for future research on RE-free Mg extrusion alloys are also proposed. We hope this review will not only off er insightful information regarding the extrusion of RE-free Mg alloys but also inspire the development of new Mg extrusion technologies. | Shuai-Ju Meng Hui Yu Shao-Da Fan Qi-Zhi Li Sung Hyuk Park Joung Sik Suh Young Min Kim Xiao-Long Nan Ming-Zhe Bian Fu-Xing Yin Wei-Min Zhao Bong Sun You Kwang Seon Shin | 2019 | Acta Metallurgica Sinica(English Letters)2019，32，2： | 6 |
| 10 | Fast removal of Pb^(2+) from water using new chelating fiber modified with acylamino and amino groups显示文摘The graft copolymerization of acrylic acid(AA) onto polyethylene glycol terephthalate(PET) fiber initiated by benzoy peroxide (BPO) was carried out in heterogeneous media.Moreover,modification of the grafted PET fiber(PET-AA) was done by changing the carboxyl group into acylamino and amino groups through the reaction with ethylenediamine.The new modified chelating fiber (NDWJN6) was characterized using elementary analysis,SEM and FT-IR spectroscopy.Adsorption kinetic curve indicated that NDWJN6 could fastly remove Pb^(2+) from water,and adsorption isotherm also indicated that NDWJN6 had high equilibrium adsorption capacity for Pb^(2+). | Ying Meng Jin Nan Wang Li Xu Ai Min Li | 2012 | Chinese Chemical Letters2012，23，4： | 6 |
| 11 | The Changes in the Awareness of Cervical Cancer Prevention and the Acceptability of HPV Vaccines among Women after Their Introduction in China显示文摘Cervical cancer is a form of malignant tumor that seriously threatens women’s health. In China,according to the cancer statistics, 98,900 new cervical cancer cases and 30,500 deaths due to cervical cancer were estimated to have occurred in2015, and the incidence and mortality rates still exhibited an upward trend[1]. | MA Quan Fu GUO Yu Lin YAN Bin FAN Chun Li XU Meng DAI Xuan WANG Ying ZOU Miao WANG Chao Nan WU Xu Feng | 2019 | Biomedical and Environmental Sciences2019，32，11： | 5 |
| 12 | Enhancement of Aggression Induced by Isolation Rearing is Associated with a Lack of Central Serotonin显示文摘Isolation rearing(IR) enhances aggressive behavior, and the central serotonin(5-hydroxytryptamine,5-HT) system has been linked to IR-induced aggression.However, whether the alteration of central serotonin is the cause or consequence of enhanced aggression is still unknown. In the present study, using mice deficient in central serotonin Tph2-/-and Lmx1 b-/-, we examined the association between central serotonin and aggression with or without social isolation. We demonstrated that central serotonergic neurons are critical for the enhanced aggression after IR. 5-HT depletion in wild-type mice increased aggression. On the other hand, application of 5-HT in Lmx1 b-/-mice inhibited the enhancement of aggression under social isolation conditions. Dopamine was downregulated in Lmx1 b-/-mice. Similar to 5-HT, L-DOPA decreased aggression in Lmx1 b-/-mice. Our results linkthe serotoninergic system directly to aggression and this may have clinical implications for aggression-related human conditions. | Yiqiong Liu Yunong Sun Xiaoyan Zhao Ji-Young Kim Lu Luo Qian Wang Xiaolu Meng Yonghui Li Nan Sui Zhou-Feng Chen Chuxiong Pan Liang Li Yan Zhang | 2019 | Neuroscience Bulletin2019，35，5： | 5 |
| 13 | Isolation,Purification and Bioactivities of Polysaccharides from Irpex lacteus显示文摘Irpex lacteus has been widely used for treating chronic glomerulonephritis as a traditional Chinese medicine.Seven water-soluble polysaccharide fractions(ILN I,ILN II,ILN III,ILA I,ILA II,ILB I and ILB II) were isolated and purified from Irpex lacteus by hot-water extraction,deproteinization,decolorization,dicthy laminoethyl(DEAE)-cellulose ion exchange and sephadex G100 chromatographies,respectively.The average molecular weights and monosaccharide composition of these polysaccharide fractions greatly differed from each other.The antitumor and antinephritis activities of the seven polysaccharide fractions were evaluated.It was found that ILN III displayed significant inhibition effects on both humar hepatocellular liver carcinoma(HepG2) and hentietta lacks(HeLa) tumor cells with IC 50 values of 60.95 and 99.95 μg/mL,respectively.ILA I exhibited significant inhibition effects on murine mesangial cells(HBZT-1) with an IC 50 value of 185.06 μg/mL.The inhibition effects of other polysaccharide fractions on these three cells were significantly different.These results suggest that the polysaccharide fractions isolated from Irpex lacteus have potential antitumor and antinephritis activities. | ZHANG Na LIU Yan LUJia-hui WANG Juan YANG Shuang ZHANG Nan MENG Qing-fan TENG Li-rong | 2012 | Chemical Research in Chinese Universities2012，28，2： | 5 |
| 14 | Interfacial Engineering of NiFeP/NiFe-LDH Heterojunction for Efficient Overall Water Splitting显示文摘In consideration of application prospect of non-noble metallic materials catalysts,the study of exploring more highly effective electrocatalysts has been focused on by researchers.Herein,a novel strategy is employed to construct a heterojunction consisting of metal phosphide Ni_(x)Fe_(y)P and layered double hydroxide(LDH)with graphene oxide(GO)as conductive support.By adjusting the molar ratio of Ni to Fe,a series of heterojunctions with mixed valence state Fe^(δ+)/Fe^(3+)and Ni^(δ+)/Ni^(2+)(δis likely close to 0)redox couples are achieved and strong synergistic effects towards overall water splitting performance are found.The optimized catalyst with a Ni/Fe molar ratio of 0.72:0.33,namely Ni_(0.7)Fe_(0.3)P/LDH/GO,delivers ultra-low overpotentials for hydrogen evolution reaction(HER)and oxygen evolution reaction(OER)of 79 and 198 mV at the current density of 10 mA·cm^(-2),respectively.Furthermore,for overall water-splitting practical application,it only requires 1.526 V at 10 mA·cm^(-2)with robust stability,which is superior to most reported electrocatalysts.Experimental results demonstrate the im-proved electronic conductivity,enlarged electrochemically active area and accelerated kinetics together account for the enhanced performance.This work supplies new prospects for the promotion and application of such heterojunction electrocatalysts in overall water splitting. | Xuanyu Long Jiazhi Meng Jiabao Gu Lanqing Ling Qianwen Li Nan Liu Kaiwen Wang Zequan Li | 2022 | Chinese Journal of Structural Chemistry2022，41，4： | 4 |
| 15 | Effect of copper precursors on the catalytic performance of Cu-ZSM-5 catalysts in N2O decomposition显示文摘Five Cu-ZSM-5 catalysts were obtained by treating Na-ZSM-5(Si/Al ratio = 15) with aqueous solutions of different Cu precursors(CuCl_2, Cu(NO_3)_2, CuSO_4, Cu(CH_3COO)_2, and ammoniacal copper(II) complex ion). After being pretreated in flowing He at 500 ℃ to form active Cu+, these catalysts exhibited quite different activities in catalytic decomposition of N_2O. CZM-AC(II)(prepared by ammoniacal copper(Ⅱ) complex ion) with 9.4 wt% Cu content was the most active among these Cu-ZSM-5 catalysts, achieving almost complete N_2O conversion at 400 ℃.CZM-CA(prepared using Cu(CH_3COO)_2 as the Cu precursor) with 2.8 wt% Cu content was the second most active catalyst among these Cu-ZSM-5 catalysts, achieving almost complete N_2O conversion at 425 ℃. CZM-CC, CZMCN, and CZM-CS prepared by using Cu Cl_2, Cu(NO_3)_2, or CuSO_4 as the Cu precursor with similar Cu contents(≈ 1.7 wt%) were the least active among these Cu-ZSM-5 catalysts, achieving ca. 90% N_2O conversion at 500 ℃.XRD, ICP, SEM, TEM, EDX-mapping, and CO-IR experiments were conducted to characterize relevant samples.The superior activity of CZM-AC(Ⅱ) can be attributed to the high contents of total Cu+and dimeric Cu+among these samples. The influence of co-fed O_2 or H_2O on the catalytic performance of typical samples was also studied. | Tao Meng Nan Ren Zhen Ma | 2018 | Chinese Journal of Chemical Engineering2018，26，5： | 4 |
| 16 | Substantial transition to clean household energy mix in rural China显示文摘The household energy mix has significant impacts on human health and climate,as it contributes greatly to many health-and climate-relevant air pollutants.Compared to the well-established urban energy statistical system,the rural household energy statistical system is incomplete and is often associated with high biases.Via a nationwide investigation,this study revealed high contributions to energy supply from coal and biomass fuels in the rural household energy sector,while electricity comprised∼20%.Stacking(the use of multiple sources of energy)is significant,and the average number of energy types was 2.8 per household.Compared to 2012,the consumption of biomass and coals in 2017 decreased by 45%and 12%,respectively,while the gas consumption amount increased by 204%.Increased gas and decreased coal consumptions were mainly in cooking,while decreased biomass was in both cooking(41%)and heating(59%).The time-sharing fraction of electricity and gases(E&G)for daily cooking grew,reaching 69%in 2017,but for space heating,traditional solid fuels were still dominant,with the national average shared fraction of E&G being only 20%.The non-uniform spatial distribution and the non-linear increase in the fraction of E&G indicated challenges to achieving universal access to modern cooking energy by 2030,particularly in less-developed rural and mountainous areas.In some non-typical heating zones,the increased share of E&G for heating was significant and largely driven by income growth,but in typical heating zones,the time-sharing fraction was<5%and was not significantly increased,except in areas with policy intervention.The intervention policy not only led to dramatic increases in the clean energy fraction for heating but also accelerated the clean cooking transition.Higher income,higher education,younger age,less energy/stove stacking and smaller family size positively impacted the clean energy transition. | Guofeng Shen Rui Xiong Yanlin Tian Zhihan Luo Bahabaike Jiangtulu Wenjun Meng Wei Du Jing Meng Yuanchen Chen Bing Xue Bin Wang Yonghong Duan Jia Duo Fenggui Fan Lei Huang Tianzhen Ju Fenggui Liu Shunxin Li Xianli Liu Yungui Li Mu Wang Ying Nan Bo Pan Yanfang Pan Lizhi Wang Eddy Zeng Chao Zhan Yilin Chen Huizhong Shen Hefa Cheng Shu Tao | 2022 | National Science Review2022，9，7： | 4 |
| 17 | Effects of Moderate Hyperventilation on Jugular Bulb Gases under Propofol or Isoflurane Anesthesia during Supratentorial Craniotomy显示文摘 | Lan Meng Shu-Qin Li Nan Ji Fang Luo | 2015 | Chinese Medical Journal2015，，10： | 4 |
| 18 | Modified subintimal plaque modification improving future recanalization of chronic total occlusion percutaneous coronary intervention显示文摘Background Subintimal plaque modification(SPM) is often performed to restore antegrade flow and facilitate subsequent lesion recanalization. This study aimed to compare the safety and efficacy of modified SPM with traditional SPM. Methods A total of 1454 consecutive patients who failed a chronic total occlusion percutaneous coronary intervention(CTO PCI) attempt and underwent SPM from January 2015 to December 2019 at our hospital were reviewed retrospectively. Fifty-four patients who underwent SPM finally were included in this study. We analyzed the outcomes of all the patients, and the primary endpoint was recanalization rate, which was defined as Thrombolysis in Myocardial Infarction(TIMI) grades 2-3 flow on angiography 30 to 90 days post-procedure. Results The baseline characteristics were similar between the two groups. In the follow-up, the recanalization rate was noticeably higher in the modified SPM group compared with the traditional SPM group(90.9% vs. 62.5%, P < 0.05). The proposed strategy in the modified group was more aggressive, including a larger balloon size(1.83 ± 0.30 vs. 2.48 ± 0.26 mm, P < 0.05) and longer subintimal angioplasty(0.59 ± 0.16 vs. 0.92 ± 0.12 mm, P < 0.05). Also, the common use of a Stingray balloon and guide catheter extension resulted in improvement of patients in the modified SMP group(12.5% vs. 100%, P < 0.05). Conclusion Modified SPM, which is associated with a high likelihood of successful recanalization, is an effective and safe CTO PCI bail out strategy. | Ruo-Fei JIA Long LI Yong ZHU Cheng-Zhi YANG Shuai MENG Yang RUAN Xiao-Jing CAO Hong-Yu HU Wei CHEN Jing NAN Xiao-Wei XIONG Jing-Jin LI Jia-Yu WANG Ze-Ning JIN | 2020 | Journal of Geriatric Cardiology2020，17，7： | 3 |
| 19 | Screening high-quality fetal bovine serum for porcine oocyte maturation in vitro显示文摘Fetal bovine serum(FBS) is widely used in cell cultures due to its high stability and easy access. It was also used as a substitute for porcine follicular fluid(PFF) in previous studies. However, FBS components are unclear, and the presence of FBS in culture media may introduce a variation from batch to batch. This study aimed to establish an effective method to screen FBS in place of PFF in the culture media for porcine oocytes in vitro. We screened FBS from different sources by using porcine fetal fibroblast cells. The effects of six FBS samples on porcine fetal fibroblast cell growth were tested via frozen cell survival assay, cell clone formation assay, cell growth curve, and cell passage activity assay. The best serum that we called GFBS(heat-inactivated FBS, cat. no. 10500-64;Gibco) showed a similar effect on the maturation and development of porcine oocytes to that of PFF and can be used as a good substitute for PFF. These results suggested that the porcine fetal fibroblast cell culture test can be used as a valuable method to screen FBS for porcine oocyte maturation and embryonic development in vitro. | Xueqing Liu Qiaoli Lang Meng Wu Xiaoyan You Qiling He Ling Luo Zijia Liu Puying Xiao Nan Huang Xi Yang Liangpeng Ge | 2019 | Animal Models and Experimental Medicine2019，2，4： | 3 |
| 20 | Platinum-coordinated graphitic carbon nitride nanosheet used for targeted inhibition of amyloid β-peptide aggregation显示文摘淀粉的肽(A) 聚集是在 Alzheimers 疾病(广告) 的致病的关键步。生产的抑制, A 的存在总数和清理的溶解对广告代表有效治疗学的策略。此处,新奇的铂(II ) 协调了 graphitic 碳氮化物(g-C 3 N 4) nanosheet (g-C 3 N 4@Pt) 被设计了 covalently 绑在 A 并且调制肽聚集和毒性。而且, g-C 3 N 4@Pt nanosheets 拥有高 photocatalytic 活动并且能氧化在可见轻照耀之上的 A,显著地 attenuating 聚集力量和 A 的 neurotoxicity。由于它穿过血大脑障碍(BBB ) 和它的好 biocompatibility 的能力, g-C 3 N 4@Pt nanosheet 是聚集的一个有希望的禁止者。这研究可以为为广告的处理使用的新奇多功能的 nanomaterials 的工程担任一个模型。 | Meng Li Yijia Guan Zhaowei Chen Nan Gao Jinsong Ren Kai Dong Xiaogang Qu | 2016 | Nano Research2016，9，8： | 3 |
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