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| 1 | Mobilization of hematopoietic progenitor cells in patients with liver cirrhosis显示文摘AIM:To test the hypothesis that liver cirrhosis is associated with mobilization of hematopoietic progenitor cells. METHODS:Peripheral blood samples from 72 patients with liver cirrhosis of varying etiology were analyzed by flow cytometry.Identified progenitor cell subsets were immunoselected and used for functional assays in vitro. Plasma levels of stromal cell-derived factor-1(SDF-1) were measured using an enzyme linked immunosorbent assay.RESULTS:Progenitor cells with a CD133 + /CD45 + CD14 + phenotype were observed in 61%of th patients.Between 1%and 26%of the peripheral bloo mononuclear cells(MNCs)displayed this phenotype Furthermore,a distinct population of c-kit + progenito cells(between 1%and 38%of the MNCs)could b detected in 91%of the patients.Additionally,18% of the patients showed a population of progenito cells(between 1%and 68%of the MNCs)that wa characterized by expression of breast cancer resistanc protein-1.Further phenotypic analysis disclosed tha the circulating precursors expressed CXC chemokin receptor 4,the receptor for SDF-1.In line with thi finding,elevated plasma levels of SDF-1 were presen in all patients and were found to correlate with th number of mobilized CD133 + progenitor cells. | Ursula M Gehling Marc Willems Kathleen Schlagner Ralf A Benndorf Maura Dandri Jrg Petersen Martina Sterneck Joerg-Matthias Pollok Dieter K Hossfeld Xavier Rogiers | 2010 | World Journal of Gastroenterology2010，16，2： | 4 |
| 2 | Peptidomies of identified neurons demonstrates a highly differentiated expression pattern of FXPRLamides in the neureendoerine system of an insect显示文摘 | Predel R Eckert M Pollok E | 2007 | J Comp Neurol2007，500，3： | 1 |
| 3 | The cerebral oscillatory network ofvoluntary tremor 显示文摘 | Pollok B Gross J Dirks M | 2004 | Physiol2004，554，3： | 1 |
| 4 | Identification of diagnostic markers for tuberculosis by proteomic fingerprinting of serum 显示文摘 | Agranoff D Fernandez-Reyes D Papadopoulos MC Rojas SA Herbster M Loosemore A Tarelli E Sheldon J Schwenk A Pollok R Rayner CF Krishna S | 2006 | Lancet2006，368，： | 1 |
| 5 | Comparison of three retroviral vector systems for transduction of nonobese diabetic/severe combined immunodeficiency mice repopulating human CD34+ cord blood cells显示文摘 | Leurs C Jansen M Pollok KE | 2003 | Hum Gene Ther2003，14，6： | 1 |
| 6 | Interferon gamma induces enterocyte resistance against infection by the intracellular pathogen Cryptosporidium parvum显示文摘 | Pollok RC Farthing MJ Bajaj-Elliott M | 2001 | Gastroenterology2001，120，1： | 1 |
| 7 | Role of colectomy in preventing recurrent primary sclerosing cholangitis in liver transplant recipients显示文摘AIM To study the published evidence on the impact of colectomy in preventing recurrent primary sclerosing cholangitis(r PSC). METHODS An unrestricted systematic literature search in Pub Med, EMBASE, Medline Ovid SP, ISI Web of Science, Lista(EBSCO) and the Cochrane library was performed on clinical studies investigating colectomy in liver transplantation(LT) recipients with and without r PSC in the liver allograft. Study quality was evaluated according to a modification of the methodological index for non-randomized studies(MINORS) criteria. Primary endpoints were the impact of presence, timing and type of colectomy on r PSC. Overall presence of inflammatory bowel disease(IBD), time of IBD diagnosis, posttransplant IBD and immunosuppressive regimen were investigated as secondary outcome.RESULTS The literature search yielded a total of 180 publications. No randomized controlled trial was identified. Six retrospective studies met the inclusion criteria of which 5 studies were graded as high quality articles. Reporting of IBD was heterogenous but in four publications, either inflammatory bowel disease, ulcerative colitis or in particular active colitis post-LT significantly increased the risk of r PSC. The presence of an intact(i.e., retained) colon at LT was identified as risk factor for r PSC in two of the high quality studies while four studies found no effect. Type of colectomy was not associated with r PSC but this endpoint was underreported(only in 33% of included studies).Neither tacrolimus nor cyclosporine A yielded a significant benefit in disease recurrence of primary sclerosing cholangitis(PSC).CONCLUSION The data favours a protective role of pre-/peri-LT colectomy in r PSC but the current evidence is not strong enough to recommend routine colectomy for r PSC prevention. | Bettina M Buchholz Panagis M Lykoudis Reena Ravikumar Joerg M Pollok Giuseppe K Fusai | 2018 | World Journal of Gastroenterology2018，24，28： | 1 |
| 8 | Persistence of extracellular baculoviral DNA in aquatic microcosms:extraction,purification,and amplification by the polymerase chain reaction (PCR)显示文摘 | England LS Pollok J Vincent M | 2005 | Mol Cell Probes2005，19，： | 1 |
| 9 | Host cell factor requirement for hepatitis C virus enzyme maturation 显示文摘 | Waxman L Whitney M Pollok B A | 2001 | Proc Natl Acad Sci USA2001，98，13： | 1 |
| 10 | Multivisceral resection for locally advanced primary colon and rectal cancer: an analysis of prognostic factors in 201 patients显示文摘 | Lehnert T Methner M Pollok A | 2002 | Ann Surg2002，235，2： | 1 |
| 11 | ALG versus OKT3 for treatment of steroid-resistant rejection in renal transplantation: ten-year follow-up results of a randomized trial显示文摘 | Stippel D L Arns W Pollok M | 2002 | Transplant Proc2002，34，6： | 1 |
| 12 | Postural tremor in Wilson's disease:a magnetoencephalographic study显示文摘 | Sudmeyer M Pollok B Hefter H | 2004 | Mov Disord2004，19，： | 1 |
| 13 | Nickel-based superalloys for advanced turbine engines:chemistry,microstructure,and properties显示文摘 | Pollok T M Tin S | | 0，，2： | 1 |
| 14 | Persistence of extracellular baculoviral DNA in aquatic microcosms:extraction,purification,and amplification by the polymerase chain reaction (PCR)显示文摘 | ENGLAND L S POLLOK J VINCENT M | 2005 | Mol Cell Probes2005，19，2： | 1 |
| 15 | Comparison of three retroviral vector systems for transduction of nonobese diabetic/severe combined immunodeficiency mice repopulating human CD34+ cord blood cells显示文摘 | Leurs C Jansen M Pollok KE | 2003 | Hum Gene Ther2003，14，： | 1 |
| 16 | Inhibition of stomatal opening in sunflower leaves by carbon monoxide, and reversal of inhibition by light显示文摘 | Pollok M Heber U Naik M S | 1989 | Planta1989，178，： | 1 |
| 17 | Tissue engineering显示文摘 | POLLOK J M VACANTI J P | 1996 | Semin Pediatr Surg1996，5，3： | 1 |
| 18 | The entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with Hepatitis B Virus显示文摘 | Tassilo Volz Lena Allweiss Mounira Ben M′Barek Michael Warlich Ansgar W. Lohse J?rg M. Pollok Alexander Alexandrov Stephan Urban J?rg Petersen Marc Lütgehetmann Maura Dandri | 2012 | Journal of Hepatology2012，，： | 1 |
| 19 | Interferon gamma induces enterocyte resistance against infection by the intracellular pathogen Cryptosporidium parvum 显示文摘 | Pollok RC Farthing MJ Bajaj-Elliott M | 2001 | Gastroenterology2001，120，1： | 1 |
| 20 | The role of everolimus in liver transplantation显示文摘 | GANSCHOW R POLLOK JM JANKOFSKY M | 2014 | Clin Exp Gastroenterol2014，7，： | 1 |
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