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| 1 | Coding metamaterials, digital metamaterials and programmable metamaterials显示文摘Metamaterials are artificial structures that are usually described by effective medium parameters on the macroscopic scale,and these metamaterials are referred to as‘analog metamaterials’.Here,we propose‘digital metamaterials’through two steps.First,we present‘coding metamaterials’that are composed of only two types of unit cells,with 0 and p phase responses,which we name‘0’and‘1’elements,respectively.By coding‘0’and‘1’elements with controlled sequences(i.e.,1-bit coding),we can manipulate electromagnetic(EM)waves and realize different functionalities.The concept of coding metamaterials can be extended from 1-bit coding to 2-bit coding or higher.In 2-bit coding,four types of unit cells,with phase responses of 0,p/2,p,and 3p/2,are required to mimic the‘00’,‘01’,‘10’and‘11’elements,respectively.The 2-bit coding has greater freedom than 1-bit coding for controlling EM waves.Second,we propose a unique metamaterial particle that has either a‘0’or‘1’response controlled by a biased diode.Based on this particle,we present‘digital metamaterials’with unit cells that possess either a‘0’or‘1’state.Using a field-programmable gate array,we realize digital control over the digital metamaterial.By programming different coding sequences,a single digital metamaterial has the ability to manipulate EM waves in different manners,thereby realizing‘programmable metamaterials’.The above concepts and physical phenomena are confirmed through numerical simulations and experiments using metasurfaces. | Tie Jun Cui Mei Qing Qi Xiang Wan Jie Zhao Qiang Cheng | 2014 | Light(Science & Applications)2014，3，1： | 130 |
| 2 | Differentiation profile of brain tumor stem cells:a comparative study with neural stem cells显示文摘大脑肿瘤干细胞(BTSC ) 的区别侧面的理解,在肿瘤房间人口之中的关键的,将通过有神经干细胞(NSC ) 的比较借卓见进 glioma 的起源并且最终产出新途径与这难处理的疾病作斗争。这里,我们从外科的 glioma 标本的有教养、净化的 BTSC 和 NSCsfrom 人的胎儿的大脑织物,并且进一步分析了他们的细胞的生物行为,他们的特别区别性质。是期望,区分进成熟神经显型的 NSC。然而, BTSC 展出了的 Inthe 一样的区别状况区分了差别。词法上,房间变得变平并且属于第一个星期,但是逐渐地此后聚集了并且改过漂浮的肿瘤范围。在相应时期期间,无差别的房间标记 CD133 和巢在的表示率在 BTSC 不停地减少,但是 1 个星期以后,他们重获上升趋势。有趣地,区分的房间标记 GFAP 和 beta-tubulinIIIshowed 表示变化逆到无差别的房间标记的。总起来说, BTSCswere 揭示了拥有一个能力抵抗区别,它实际上代表 glioma 的恶意的行为。 | Quan Bin Zhang Xiao Yan Ji Qiang Huang Jun Dong Yu De Zhu Qing Lan | 2006 | Cell Research2006，16，12： | 34 |
| 3 | Preliminary characterization of acute aortic dissection in the mainland of China显示文摘经济地在更少和更多之中在尖锐大动脉的解剖( AAD )的特征探索差别的目的从尖锐大动脉的解剖( IRAD )的国际注册表与各种各样的文化和赛跑数据来源报告开发了国家,中国( MC )的大陆由寻找 PubMed 数据库是镇定的并且从2000年1月的中国杂志全文的数据库到2009年3月 .Study 选择从包含大量案例和 comple 的 IRAD 和 MC 的那些报告并且从包含病人们在 MC 由一样的医学中心报导了的最大的数字的文章的数据从 MC 被拿进 statistics.Results AAD 病人是比 IRAD 国家和在中国组的男病人的百分比显著地年轻的比 IRAD 国家高(80.7%对68.6%, P 0.001 )。在 MC 的病人多半是更少除了任何焦点的神经病学的赤字与典型症状和符号介绍。与 IRAD 组,不同中国病人是容易的经历磁性的回声成像(MRI ) 做 AAD 的诊断(45.5%vs.11.6% , P 0.001 ) 。在里面医院死亡在 2 个组之间是类似的,但是在 MC 的 AAD 病人的仅仅更小的比例经历了外科或在 MC 的病人被给看的 AAD 和在在 MC 和 IRAD 之间的一些临床的变量的差别的一般特征组织的 medicaltreatment.Conclusions 仍然存在。 | WANG Dong-jin FAN Fu-dong WANG Qiang LI Qing-guo ZHOU Qing WU Zhong SHI Guang-fei | 2011 | Chinese Medical Journal2011，，11： | 23 |
| 4 | BMAL1 knockout macaque monkeys display reduced sleep and psychiatric disorders显示文摘Circadian disruption is a risk factor for metabolic, psychiatric and age-related disorders, and non-human primate models could help to develop therapeutic treatments. Here, we report the generation of BMAL1 knockout cynomolgus monkeys for circadian-related disorders by CRISPR/Cas9 editing of monkey embryos. These monkeys showed higher nocturnal locomotion and reduced sleep, which was further exacerbated by a constant light regimen. Physiological circadian disruption was reflected by the markedly dampened and arrhythmic blood hormonal levels. Furthermore, BMAL1-deficient monkeys exhibited anxiety and depression, consistent with their stably elevated blood cortisol, and defective sensory processing in auditory oddball tests found in schizophrenia patients. Ablation of BMAL1 up-regulated transcriptional programs toward inflammatory and stress responses, with transcription networks associated with human sleep deprivation, major depressive disorders, and aging. Thus, BMAL1 knockout monkeys are potentially useful for studying the physiological consequences of circadian disturbance, and for developing therapies for circadian and psychiatric disorders. | Peiyuan Qiu Jian Jiang Zhen Liu Yijun Cai Tao Huang Yan Wang Qiming Liu Yanhong Nie Fang Liu Jiumu Cheng Qing Li Yun-Chi Tang Mu-ming Poo Qiang Sun Hung-Chun Chang | 2019 | National Science Review2019，6，1： | 21 |
| 5 | From concept to reality-A review to the primary test stand and its preliminary application in high energy density physics显示文摘Pulsed power technology,whereas the electrical energy stored in a relative long period is released in much shorter timescale,is an efficient method to create high energy density physics(HEDP)conditions in laboratory.Around the beginning of this century,China Academy of Engineering Physics(CAEP)began to build some experimental facilities for HEDP investigations,among which the Primary Test Stand(PTS),a multi-module pulsed power facility with a nominal current of 10 MA and a current rising time~90 ns,is an important achievement on the roadmap of the electro-magnetically driven inertial confinement fusion(ICF)researches.PTS is the first pulsed power facility beyond 10 TW in China.Therefore,all the technologies have to be demonstrated,and all the engineering issues have to be overcome.In this article,the research outline,key technologies and the preliminary HEDP experiments are reviewed.Prospects on HEDP research on PTS and pulsed power development for the next step are also discussed. | Jianjun Deng Weiping Xie Shuping Feng Meng Wang Hongtao Li Shengyi Song Minghe Xia Ji Ce An He Qing Tian Yuanchao Gu Yongchao Guan Bin Wei Xianbin Huang Xiaodong Ren Jiakun Dan Jing Li Shaotong Zhou Hongchun Cai Siqun Zhang Kunlun Wang Qiang Xu Yujuan Wang Zhaohui Zhang Guilin Wang Shuai Guo Yi He Yiwei Zhou Zhanji Zhang Libing Yang Wenkang Zou | 2016 | Matter and Radiation at Extremes2016，1，1： | 19 |
| 6 | Comprehensive metabolomics expands precision medicine for triple-negative breast cancer显示文摘Metabolic reprogramming is a hallmark of cancer.However,systematic characterizations of metabolites in triple-negative breast cancer(TNBC)are still lacking.Our study profiled the polar metabolome and lipidome in 330 TNBC samples and 149 paired normal breast tissues to construct a large metabolomic atlas of TNBC.Combining with previously established transcriptomic and genomic data of the same cohort,we conducted a comprehensive analysis linking TNBC metabolome to genomics.Our study classified TNBCs into three distinct metabolomic subgroups:C1,characterized by the enrichment of ceramides and fatty acids;C2,featured with the upregulation of metabolites related to oxidation reaction and glycosyl transfer;and C3,having the lowest level of metabolic dysregulation.Based on this newly developed metabolomic dataset,we refined previous TNBC transcriptomic subtypes and identified some crucial subtype-specific metabolites as potential therapeutic targets.The transcriptomic luminal androgen receptor(LAR)subtype overlapped with metabolomic C1 subtype.Experiments on patient-derived organoid and xenograft models indicate that targeting sphingosine-1-phosphate(S1P),an intermediate of the ceramide pathway,is a promising therapy for LAR tumors.Moreover,the transcriptomic basal-like immune-suppressed(BLIS)subtype contained two prognostic metabolomic subgroups(C2 and C3),which could be distinguished through machine-learning methods.We show that N-acetyl-aspartyl-glutamate is a crucial tumor-promoting metabolite and potential therapeutic target for high-risk BLIS tumors.Together,our study reveals the clinical significance of TNBC metabolomics,which can not only optimize the transcriptomic subtyping system,but also suggest novel therapeutic targets.This metabolomic dataset can serve as a useful public resource to promote precision treatment of TNBC. | Yi Xiao Ding Ma Yun-Song Yang Fan Yang Jia-Han Ding Yue Gong Lin Jiang Li-Ping Ge Song-Yang Wu Qiang Yu Qing Zhang François Bertucci Qiuzhuang Sun Xin Hu Da-Qiang Li Zhi-Ming Shao Yi-Zhou Jiang | 2022 | Cell Research2022，32，5： | 18 |
| 7 | Incubation and application of transgenic green fluorescent nude mice in visualization studies on glioma tissue remodeling显示文摘 | DONG Jun, DAI Xing-liang LU Zhao-hui FEI Xi-feng CHEN Hua ZHANG Quan-bin ZHAO Yao-dong WANG Zhi-min WANG Ai-dong LAN Qing HUANG Qiang | 2012 | Chinese Medical Journal2012，，24： | 17 |
| 8 | A highly alkaline-stable metal oxide@metal-organic framework composite for high-performance electrochemical energy storage显示文摘Most metal-organic frameworks(MOFs) hardly maintain their physical and chemical properties after exposure to alkaline aqueous solutions,thus precluding their use as potential electrode materials for electrochemical energy storage devices.Here,we present the design and synthesis of a highly alkaline-stable metal oxide@MOF composite,Co3O4 nanocube@Co-MOF(Co3O4@Co-MOF),via a controllable and facile one-pot hydrothermal method under highly alkaline conditions.The obtained composite possesses exceptional alkaline stability,retaining its original structure in 3.0 M KOH for at least 15 days.Benefitting from the exceptional alkaline stability,unique structure,and larger surface area,the Co3O4@Co-MOF composite shows a specific capacitance as high as 1020 F g-1 at 0.5 A g-1 and a high cycling stability with only 3.3% decay after 5000 cycles at 5 A g-1.The as-constructed solid-state flexible device exhibits a maximum energy density of 21.6 mWh cm-3. | Shasha Zheng Qing Li Huaiguo Xue Huan Pang Qiang Xu | 2020 | National Science Review2020，7，2： | 16 |
| 9 | Minimally invasive keyhole approaches for removal of tumors of the third ventricle显示文摘最近的年里的背景,锁眼微外科成为了现代最低限度地侵略的神经外科的一个重要题目。在这研究,避免不必要的织物损害的最低限度地侵略的技术被使用为在内的第三个室的肿瘤的移动精制传统的途径一有限起作用走。个性化的锁眼途径根据第三个室的肿瘤和他们的生长模式的特征被设计的方法。一系列锁眼接近正面的途径例如眼窝上的潜水艇, infratentorial 在上小脑的途径,内部半球的 transcallosal 途径, pterional 途径被采取其次地,分别地卓越地或旁边地先前地进入第三个室。34 的一个总数移开肿瘤在或把包括的 11craniopharyngiomas, 10 个垂体腺瘤, 2 pinealomas, 1 cholesteatoma, 3 germinomas,和 7gliomas 扩大了到第三个室。病人的全部的肿瘤切除术在 27 被做的结果(79.4%) ,和在 7 个病人(20.6%) 的小计切除术。剩余肿瘤由于到静脉的 germinoma 的紧密的坚持盖伦(1 个病人) ,到垂体梗(3 ) 的颅咽管瘤,松果状的区域 gliomas (1 ) 的 supratentorial 延期, gliomas (1 ) 的 suprasellar 延期和巨人垂体腺瘤(1 ) 。象大脑殴打,手术后的出血和感染那样的复杂并发症没与锁眼途径被联系。因为事件,扩大切口或扩大骨头拍动没在操作或不适当的暴露期间被做。结论锁眼途径在在第三个室深深地就坐的肿瘤的外科的治疗安全、有效、最低限度地侵略。个性化的锁眼途径保证成功的治疗。在第三个室的上面的中间的部分的肿瘤能被暴露由内部半球的 transcallosal 锁眼途径。肿瘤以后第三个室可以被 infratentorial 在上很好暴露小脑的锁眼途径。肿瘤前面第三个室能被一条眼窝上的 subfrontalkeyhole 途径或一条 pterional 锁眼途径进入。 | LAN Qing DONG Jun HUANG Qiang | 2006 | Chinese Medical Journal2006，，17： | 13 |
| 10 | Epidemiological Data of Work-Related Musculoskeletal Disorders—China,2018–2020显示文摘Summary What is already known about this topic?In recent decades,work-related musculoskeletal disorders(WMSDs)have become increasingly prominent and have become an important issue that is of universal concern and an urgent need to be solved in all countries of the world.What is added by this report?The top three industries or occupational groups with the highest standardized prevalence rate of WMSDs were flight attendants,medical staff,and vegetable greenhouses in that order.Women workers were 1.5 times more likely to suffer from WMSDs than men workers. | Ning Jia Huadong Zhang Ruijie Ling Yimin Liu Gang Li Zaoliang Ren Yan Yin Hua Shao Hengdong Zhang Bing Qiu Meibian Zhang Dayu Wang Qiang Zeng Rugang Wang Jianchao Chen Danying Zhang Liangying Mei Yongquan Liu Jixiang Liu Chengyun Zhang Tianlai Li Qing Xu Ying Qu Xueyan Zhang Xin Sun Zhongxu Wang | 2021 | China CDC weekly2021，3，18： | 13 |
| 11 | The roles of surfactant protein D during Aspergillus fumigatus infection in human corneal epithelial cells显示文摘AIM: To investigate roles of surfactant protein D (SP-D) and relative cytokines in human corneal epithelial(HCE) cells exposed to aspergillus fumigatus (AF) antigens.METHODS: HCE cells cultured in vitro with AF antigens and sampled at 0, 0.5, 1 hour, 2, 4, 6 and 8 hours. The expression of SP-D mRNA was evaluated by semiquantitative reverse transcription-polymerase chain reaction (RT-PCR).The expression of SP-D protein was shown by ELISA and immunocytochemistry SP methods. The expression of NF-κB and relative downstream cytokines such as TNF-α, IL-1β, IL-8 and IL-10 in supernatant fluid were measured by ELISA.RESULTS: SP-D mRNA and protein were detected in untreated HCE cells. The expression of SP-D and the relative downstream cytokines rose after being stimulated with AF antigens. SP-D mRNA began to rise at 0.5 hour and the most significantly peak was in 2 hours. The protein of SP-D in supernatant fluid had the same trend with mRNA. Immunocytochemistry of SP-D showed positive expression and gradually increased to 6 hours, and then the expression began to decline. NF-κB was activated after treated by AF antigens and the changes had correlation with SP-D. TNF-α, IL-1β, IL-8 and IL-10 began to rise after given AF antigens 1 hour and were 1.82, 1.43, 1.12 and 1.28 times higher than the untreated HCE cells separately. The expression of TNF-α and IL-1β reached the peak at 2 hours, separately 2.80 and 2.86 times than the untreated. The expression of IL-8 and IL-10 gradually increased with a time-dependent manner.CONCLUSION: HCE cells exists SP-D and it may play a significant role in pathogenesis of keratomycosis. AF may induce human corneal epithelial cells to express inflammatory cytokines via SP-D and NF-κB pathway. SP-D possibly mediates the recognition to AF mycelium. | Cheng-Ye Che Wen-Yan Jia Qiang Xu Na Li Li-Ting Hu Nan Jiang Jing Lin Qing Wang and Gui-Qiu Zhao | 2012 | International Journal of Ophthalmology(English edition)2012，5，1： | 12 |
| 12 | Correlation between expression and differentiation of endocan in colorectal cancer显示文摘AIM: To investigate the expression frequency of endocan in colorectal cancer and analyze the relationship between endocan expression and clinical parameters and to study the role of endocan in colorectal carcinogenesis. METHODS: Expression of endocan in 72 tumor tissue samples of colorectal cancer as well as in 27 normal mucous membrane tissue samples was analyzed using in situ hybridization, immunohistochemistry on tissue microarray, Western blot and reverse-transcript polymerase chain reaction (RT-PCR). RESULTS: The expression of endocan was higher in normal colon and rectum tissue samples than in cancerous tissue samples (mRNA = 92.6%, protein = 36%), and was lower in colorectal cancer tissue samples (mRNA = 70.4%, protein = 36.1%). No correlation was found between staining intensity and clinical parameters such as sex, age, tumor size andTNM stage. However, the expression of endocan was positively correlated with the tissue differentiation in colorectal cancer. CONCLUSION: The expression of endocan is down- regulated in colorectal cancer and is positively correlated with the tissue differentiation in colorectal cancer, suggesting that the expression of endocan is associated with development and differentiation of colorectal cancer. | Li Zuo Su-Mei Zhang Ruo-Lei Hu Hua-Qing Zhu Qing Zhou Shu-Yu Gui Qiang Wu Yuan Wang | 2008 | World Journal of Gastroenterology2008，14，28： | 11 |
| 13 | Modeling the land surface reflectance for optical remote sensing data in rugged terrain显示文摘A model for topographic correction and land surface reflectance estimation for optical remote sensing data in rugged terrian is presented.Considering a directional-directional reflectance that is used for direct solar irradiance correction and a hemispheric-directional reflectance that is used for atmospheric diffuse irradiance and terrain background reflected irradiance correction respectively,the directional reflectance-based model for topographic effects removing and land surface reflectance calculation is developed by deducing the directional reflectance with topographic effects and using a radiative transfer model.A canopy reflectance simulated by GOMS model and Landsat/TM raw data covering Jiangxi rugged area were taken to validate the performance of the model presented in the paper.The validation results show that the model presented here has a remarkable ability to correct topography and estimate land surface reflectance and also provides a technique method for sequently quantitative remote sensing application in terrain area. | WEN JianGuang LIU QinHuo XIAO Qing LIU Qiang LI XiaoWen | 2008 | Science China Earth Sciences2008，51，8： | 11 |
| 14 | Investigation on Work-Related Musculoskeletal Disorders--China, 2018−2019显示文摘What is already known about this topic?Work-related musculoskeletal disorders(WMSDs)have a high prevalence and seriously harmful,which has attracted extensive attention in various countries in the world.Currently,the occurrence and rules of WMSDs in key industries are not known in China.What is added by this report?The prevalence of WMSDs is relatively high among professional populations in key industries in China,with the most commonly affected body parts concentrated in neck,shoulders,and low back and increasing with age and working years.What are the implications for public health practice?This study determined the prevalence and distribution characteristics of WMSDs in key industries in China and provided scientific evidence to recommend for inclusion of WMSDs in the new revision of the list of occupational diseases in China. | Ning Jia Huadong Zhang Ruijie Ling Yimin Liu Gang Li Zaoliang Ren Yan Yin Hua Shao Hengdong Zhang Bing Qiu Meibian Zhang Dayu Wang Qiang Zeng Rugang Wang Jianchao Chen Danying Zhang Liangying Mei Yongquan Liu Jixiang Liu Chengyun Zhang Tianlai Li Qing Xu Ying Qu Xueyan Zhang Xin Sun Zhongxu Wang | 2020 | China CDC weekly2020，2，18： | 11 |
| 15 | Effect of Morinda officinalis capsule on osteoporosis in ovariectomized rats显示文摘AIM:To explore the therapeutic effects of Morinda officinalis capsules(MOP) on osteoporosis in ovariectomized rats.METHOD:Six-month-old female Sprague–Dawley rats were induced for postmenopausal osteoporosis(PMOP) by bilateral ovariectomy and divided into seven groups as follows:sham-operated group,ovariectomized(OVX) control group,OVX treated with xianlinggubao(XLGB)(270 mg·kg-1·d-1),OVX treated with alendronate sodium(ALN)(3 mg·kg-1·d-1),and OVX treated with Morinda officinalis capsule(MOP) of graded doses(90,270 and 810 mg·kg-1·d-1) groups.Oral treatments were administered daily on the 4th week after ovariectomy and lasted for 12 weeks.The bone mineral density was evaluated by dual-energy X-ray absorptiometry.The tartrate-resistant acid phosphatase(TRAP),alkaline phosphatase(AKP),and osteocalcin(OC) levels in the serum and plasma were determined by standard colorimetric and enzyme immunoassays methods.Bone biomechanical properties and morphological parameters were analyzed by three-point bending test and histomorphometry respectively.RESULTS:Morinda officinalis capsules at all doses were able to significantly prevent the OVX-induced loss of bone mass due to diminishing serum AKP and TRAP levels while elevating OC level in the plasma.Morinda officinalis capsules also enhanced the bone strength and prevented the deterioration of trabecular microarchitecture.CONCLUSION:Morinda officinalis capsules possess potent anti-osteoporotic activity in OVX rats which could be an effective treatment for postmenopausal osteoporosis. | LI Ye Lü Shan-Shan TANG Gui-Ying HOU Min TANG Qing ZHANG Xiao-Na CHEN Wei-Hai CHEN Gang XUE Qiang ZHANG Cong-Cong ZHANG Ji-Fen CHEN Yi XU Xiao-Yu | 2014 | Chinese Journal of Natural Medicines2014，12，3： | 10 |
| 16 | Impacts of PLL on the DFIG-based WTG’s Electromechanical Response Under Transient Conditions:Analysis and Modeling显示文摘Increased penetration of wind energy in the electric grid has necessitated studying the impact of wind integration on the transient stability of the power system,with urgency to develop appropriate electromechanical models of the wind turbine generator(WTG).The representation and control of the WTG’s electric signals are typically in a rotational dq coordinate system whose reference angle is provided by a phase-lockedloop(PLL).The PLL is commonly considered as a measurement device and is often absent in existing WTG electromechanical models.This paper studies the impact of PLL on the DFIG-based WTG electromechanical response by theoretical and simulation analyses.The dynamics of the PLL are found to greatly influence the WTG electromechanical response,suggesting that PLL should be regarded as an indispensable control loop rather than a measurement device,and its impact should be modeled when establishing the WTG electromechanical model. | Dongliang Zhang Yajing Wang Jiabing Hu Shicong Ma Qing He Qiang Guo | 2016 | CSEE Journal of Power and Energy Systems2016，2，2： | 10 |
| 17 | Correlation of Seven Biological Factors(Hsp90α,p53,MDM2,Bcl-2,Bax,Cytochrome C,and Cleaved caspase3)with Clinical Outcomes of ALK+ Anaplastic Large-cell Lymphoma显示文摘Objective To explore correlation of seven apoptosis‐related proteins (Hsp90α,p53,MDM2,Bcl‐2,Bax,Cytochrome C,and Cleaved caspase3) with clinical outcomes of ALK+ anaplastic large‐cell lymphoma (ALCL).Methods Using immunohistochemistry and immunofluorescence double staining methods,the expressions of these seven apoptosis‐associated proteins were studied to clarify their relationship with clinical outcomes of 36 ALK+ and 25 ALK‐ systemic ALCL patients enrolled between 1996 and 2006.The relationship of these apoptosis‐regulating proteins with NPM‐ALK status was also evaluated with the tyrosine inhibitor herbimycin A (HA) in vitro by immunocytochemistry,Western blotting and flow cytometric assays.Results The presence of Hsp90α‐,MDM2‐,Bax‐,Cytochrome C,and Cleaved caspase3‐positive tumor cells was found significantly different in ALK+ and ALK‐ ALCLs ,which was correlated with highly favorable clinical outcome.The Bcl‐2‐ and p53‐positive tumor cells were found in groups of patients with unfavorable prognosis.Inhibition of NPM‐ALK by HA could reactivate the p53 protein and subsequent apoptosis‐related proteins and therefore induced apoptosis in ALK+ ALCL cells.Conclusion Our results suggest that these seven proteins might be involved in apoptosis regulation and associated with clinical outcome of ALK+ systemic ALCLs.We also reveal a dynamic chain relation that NPM‐ALK regulates p53 expression and subsequent apoptosis cascade in ALK+ ALCLs. | LI Hui Ling HUANG Xue Ping ZHOU Xin Hua JI Tian Hai WU Zi Qing WANG Zhi Qiang JIANG Hui Yong LIU Fan Rong ZHAO Tong | 2011 | Biomedical and Environmental Sciences2011，24，6： | 9 |
| 18 | Malnutrition and Quality of Life in Chinese Cancer Patients: a Clinical Study of 23,994 Subjects显示文摘Background Malnutrition is common in patients with cancer,and can negatively impact their quality of life(QoL)and even survival.However,there is currently no large data available on the prevalence of malnutrition in Chinese cancer patients.This study evaluated the prevalence of malnutrition and the QoL of Chinese patients with locoregional,recurrent or metastatic cancer.Methods We conducted a nationwide observational,multi-center,hospital-based cross-sectional study within the Chinese Society of Nutritional Oncology(CSNO)Network.All of the patients were diagnosed with one of the following 18 different types of malignant tumors:lung cancer,gastric cancer,liver cancer,colorectal cancer,breast cancer,esophageal cancer,cervical cancer,endometrial cancer,nasopharyngeal carcinoma,malignant lymphoma,leukemia,pancreatic cancer,ovarian cancer,prostate cancer,bladder cancer,brain cancer,biliary tract malignant tumors or gastrointestinal stromal tumors.These patients were enrolled from 72 hospitals located in different regions of China.The patients’nutritional status was evaluated based on the body mass index(BMI),loss of bodyweight,laboratory measurements and patient generated-subjective global assessment(PG-SGA)scores.The cancer patients’physical status and QoL were assessed by the Karnofsky Performance Status(KPS)questionnaire and the European Organization for Research and Treatment of Cancer(EORTC)QLQ-C30 questionnaire,respectively.Results From December 2013 to April 2016,23,994 patients hospitalized for cancer treatment(such as surgery,chemotherapy or radiotherapy)were enrolled in the study.The patients included 12,494(52.9%)males and 11,124(47.1%)females.The mean age was 55.8±13.7 years.The proportions of patients in cancer stagesⅠ,Ⅱ,Ⅲ,Ⅳand uncertain were 11.5%,20.3%,27.5%,30.2%and 10.5%,respectively.Among the 23,994 inpatients,the proportions of patients who were underweight(BMI<18.5 kg/m2),normal(18.5 kg/m2 | Hong Xia Xu Chun Hua Song Zhen Ming Fu Chang Wang Zeng Qing Guo Yuan Lin Ying Ying Shi Wen Hu Yi Ba Su Yi Li Zeng Ning Li Kun Hua Wang Jing Wu Ying He Jia Jun Yang Cong Hua Xie Fu Xiang Zhou Xin Xia Song Gong Yan Chen Wen Jun Ma Su Xia Luo Zi Hua Chen Ming Hua Cong Hu Ma Chun Ling Zhou Wei Wang Qi Luo Yong Mei Shi Yu Mei Qi Hai Ping Jiang Wen Xian Guan Jun Qiang Chen Jia Xin Chen Yu Fang Lan Zhou Yong Dong Feng Rong Shao Tan Tao Li Jun Wen Ou Qing Chuan Zhao Jian Xiong Wu Min Weng Qing Hua Yao Jiu Wei Cui Wei Li Han Ping Shi the Investigation on Nutrition Status and Clinical Outcome of Common Cancers(INSCOC)Group | 2021 | Journal of Nutritional Oncology2021，6，1： | 8 |
| 19 | Different dissecting orders of the pulmonary bronchus and vessels during right upper lobectomy are associated with surgical feasibility and postoperative recovery for lung cancer patients显示文摘Background: Right upper lobectomy(RUL) for lung cancer with di erent dissecting orders involves the most vari?able anatomical structures, but no studies have analyzed its e ects on postoperative recovery. This study compared the conventional surgical approach, VAB(dissecting pulmonary vessels first, followed by the bronchus), and the alter?native surgical approach, a BVA(dissecting the posterior ascending arterial branch first, followed by the bronchus and vessels) on improving surgical feasibility and postoperative recovery for lung cancer patients.Methods: According to the surgical approach, consecutive lung cancer patients undergoing RUL were grouped into a BVA and VAB cohorts. Their clinical, pathologic, and perioperative characteristics were collected to compare periop?erative outcomes.Results: Three hundred one patients were selected(109 in the a BVA cohort and 192 in the VAB cohort). The mean operation time was shorter in the a BVA cohort than in the VAB cohort(164 vs. 221 min, P < 0.001), and less blood loss occurred in the a BVA cohort(92 vs. 141 m L, P < 0.001). The rate of conversion to thoracotomy was lower in the a BVA cohort than in the VAB cohort(0% vs. 11.5%, P < 0.001). The mean duration of postoperative chest drainage was shorter in the a BVA cohort than in the VAB cohort(3.6 vs. 4.5 days, P rvival was n= 0.001). The rates of postoperative complica?tions were comparable(P = 0.629). The median overall suot arrived in both cohorts(P > 0.05). The median disease?free survival was comparable for all patients in the two cohorts(not arrived vs. 41.97 months) and for patients with disease recurrences(13.25 vs. 9.44 months)(both P > 0.05). The recurrence models in two cohorts were also comparable for patients with local recurrences(6.4% vs. 7.8%), distant metastases(10.1% vs. 8.3%), and both(1.8% vs. 1.6%)(all P > 0.05).Conclusions: Dissecting the right upper bronchus before turning over the lobe repeatedly and dissecting veins via the a BVA approach during RUL would promote surgical feasibility and achieve comparable postoperative recovery for lung cancer patients. | Hao-Ran Zhai Xue-Ning Yang Qiang Nie Ri-Qiang Liao Song Dong Wei Li Ben-Yuan Jiang Jin-Ji Yang Qing Zhou Hai-Yan Tu Xu-Chao Zhang Yi-Long Wu Wen-Zhao Zhong | 2017 | Chinese Journal of Cancer2017，36，10： | 8 |
| 20 | Influence of resonator diameter on a miniature thermoacoustic Stirling heat engine显示文摘A small scale thermoacoustic Stirling engine (TASHE) is simulated according to the linear ther-moacoustic theory. The computed results show that in a small scale thermoacoustic Stirling heat en-gine, the diameter of the resonance tube might have important influences on the working frequency and the performance of the engine, which are always neglected in a large scale system. Likewise, the analysis and experimental results show that in order to obtain better engine performance, the diameter of the resonance tube must be chosen appropriately according to the looped tube dimension and the input heating power. This provides an effective way to miniaturize the thermoacoustic Stirling heat en-gine. According to the computation and analysis, a small scale engine was built, the resonance tube length and diameter of which were about 350 mm and 20 mm, respectively, and the working frequency was about 282 Hz. When the input heating power was about 637 W, the maximal peak to peak pressure amplitude and pressure ratio reached 0.22 MPa and 1.116, respectively, which were able to drive a thermoacoustic refrigerator or an electrical generator. | ZHOU Gang LI Qing LI ZhengYu LI Qiang | 2008 | Chinese Science Bulletin2008，53，1： | 8 |
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