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| 1 | Surgical Management of Macular Epiretinal Membranes显示文摘Purpose: To evaluate the effects of surgical treatment on macular epiretinal membranes.Methods: Vitrectomy and membrane removal were undergone for idopathic or secondary macular epiretinal membrane.Results: Fourteen eyes of 15 patients (93%) had vision improvement after operation in which 8 eyes (57%) increased 3 or more Senellen lines. Only one case suffered from paracentral scotoma. No other complications were noted. Conclusion: Surgical management of macular epiretinal membrane is safe and effective with good visual outcome and few complications. Eye Science 1996; 12:140 -144. | Fangtian Dong, Ruifang SuiChinese Acadamy of Medical Science, Peking Union Medical College Hospital, Beijing 100730, China | 1996 | Eye Science1996，16，3： | 6 |
| 2 | Viewpoint Optimization Using Genetic Algorithm for Flying Robot Inspection of Electricity Transmission Tower Equipment显示文摘To fully exploit the limited flight-time of the flying robot, and ensure the successful visibility of target, viewpoint optimization is proposed in this paper for the inspection of electricity transmission tower equipment with an optimization function to determine the best viewpoints in a local viewpoint region. The local viewpoint regions are generated from the local objective regions which are determined by the geometrical structure of a priori3 D model for the electricity transmission tower equipment.The optimization function is structured based on three factors including visibility, viewing quality and observation distance. In addition, the fitness function of genetic algorithm is used to find the optimal viewpoint. The experimental results demonstrate the effectiveness and efficiency of the proposed viewpoint selection algorithm. | YANG Guotian DONG Ruifang WU Hua LIU Chang'an | 2014 | Chinese Journal of Electronics2014，23，2： | 6 |
| 3 | New research trends on high-precision time transfer technology显示文摘High-precision time transfer plays an important role in the areas of fundamental research and applications. Accompanying w ith the remarkable improvements in the ability of generating and measuring high-accuracy time-frequency signal,seeking for new time-transfer techniques betw een distant clocks w ith much further improved accuracy attracts attentions w orld-w idely. The time-transfer technique based on optical pulses has the highest precision presently,and the further improvement in the accuracy is heavily dependent on the time-domain properties of the pulse as w ell as the sensitivity of the applied measurement on the exchanged pulse. The application of optical frequency comb in time transfer for a precision up to femtosecond level are currently the focus of much interest,and has recently achieved many breakthroughs. Further investigations show that,utilizing quantum techniques,i.e. quantum measurement technique and quantum optical pulse source,can lead to a new limit on the measured timing information. Furthermore,it can be immune from atmospheric parameters,such as pressure,temperature,humidity and so on.Such quantum improvements on time-transfer have a bright prospect in the future applications requiring extremely high-accuracy timing and ranging. The potential achievements w ill form a technical basis for the future realization of sub-femtosecond time transfer system. | DONG Ruifang QUAN Run'ai HOU Feiyan WANG Shaofeng XIANG Xiao ZHOU Conghua WANG Mengmeng LIU Tao ZHANG Shou'gang | 2015 | Instrumentation2015，2，4： | 5 |
| 4 | The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients显示文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus. | Jin Liu Lingling Bian Li Ji Yang Chen Heng Chen Yong Gu Bingqin Ma Wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua Ma Hui Jin Xing Shi Heng Miao Bing Xin Yan Zhu Zhenwen Zhang Ruifang Bu Lan Xu Guangde Shi Wei Tang Wei Li Dongmei Zhou Jun Liang Xingbo Cheng Bimin Shi Jixiang Dong Ji Hu Chen Fang Shao Zhong Weinan Yu Weiping Lu Chenguang Wu Li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing Zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun Xie Minmin An Wei Zhang Zhixiao Wang Yun Cai Qi Fu Yu Fu Shuai Zheng Fan Yang Qingfang Hu Hao Dai Yu Jin Zheng Zhang Kuanfeng Xu Yifan Li Jie Shen Hongwen Zhou Wei He Xuqin Zheng Xiao Han Liping Yu Jinxiong She Mei Zhang Tao Yang | 2016 | Science China(Life Sciences)2016，59，9： | 5 |
| 5 | Adjunctive sepsis therapy with aminophylline(STAP):a randomized controlled trial显示文摘Background:Sepsis is a serious disease caused by infection.Aminophylline has anti-asthma and anti-inflammatory effects.We aimed to explore the safety and effect of aminophylline in sepsis.Methods:We conducted a clinical randomized controlled trial involving 100 patients diagnosed with sepsis within 48 h after intensive care unit(ICU)admission in two sites.All patients were randomized in a 1:1 ratio to receive standard therapy with or without aminophylline.The primary clinical outcome was all-cause mortality at 28 days.Results:From September 27,2018 to February 12,2020,we screened 277 septic patients and eventually enrolled 100 patients,with 50 assigned to the aminophylline group and 50 to the usual-care group.At 28 days,7 of 50 patients(14.0%)in the aminophylline group had died,compared with 16 of 50(32.0%)in the usual-care group(P=0.032).Cox regression showed that the aminophylline group had a lower hazard of death(hazard ratio=0.312,95%confidence interval:0.129–0.753).Compared with the usual-care group,patients in the aminophylline group had a longer survival time(P=0.039 by the log-rank test).The effects of aminophylline on vasopressor dose,oxygenation index,and sequential organ failure assessment score were timedependent with treatment.There were no significant differences in total hospitalization days,ICU hospitalization days,and rates of serious adverse events(all P>0.05).No adverse events were observed in the trial.Conclusions:Aminophylline as an adjunct therapy could significantly reduce the risk of death and prolong the survival time of patients with sepsis.Trial registration:ChiCTR.org.cn,ChiCTR1800019173. | Ruifang Zhang Huan Liu Dongmei Dai Xianfei Ding Dong Wang Yan Wang Xuexiu Shi Shuguang Zhang Xiaoguang Duan Haixu Wang Yonggang Luo Shaohua Liu Bing Han Xiaojuan Zhang Yu Fang Jing Yang Wangbin Xu Tongwen Sun | 2022 | Chinese Medical Journal2022，135，23： | 2 |
| 6 | QTL mapping of quality traits in peanut using whole-genome resequencing显示文摘Oil and protein content and fatty acid composition are quality traits in peanut.Elucidating the genetic mechanisms underlying these traits may help researchers to obtain improved cultivars by molecular breeding.Whole-genome resequencing of a recombinant inbred population of 318 lines was performed to construct a high-density linkage map and identify QTL for peanut quality.The map,containing 4561 bin markers,covered 2032 c M with a mean marker density of 0.45 c M.A total of 110 QTL for oil and protein content,and fatty acid composition were mapped on the 18 peanut chromosomes.The QTL q A05.1 was detected in four environments and showed a major phenotypic effect on the contents of oil,protein,and six fatty acids.The genomic region spanned by q A05.1,corresponding to a physical interval of approximately 1.5 Mb,contains two SNPs polymorphic between the parents that could cause missense mutations.The two SNP sites were employed as KASP markers and validated using lines with extremely high and low oil contents.These sites may be useful in the marker-assisted breeding of peanut cultivars with high oil contents. | Ziqi Sun Feiyan Qi Hua Liu Li Qin Jing Xu Lei Shi Zhongxin Zhang Lijuan Miao Bingyan Huang Wenzhao Dong Xiao Wang Mengdi Tian Jingjing Feng Ruifang Zhao Xinyou Zhang Zheng Zheng | 2022 | The Crop Journal2022，10，1： | 2 |
| 7 | Experimental Entanglement Distillation of Macroscopic Quantum States 显示文摘 | DONG RUIFANG LASSEN MIKAEL HEERSINK JOEL | 2008 | Nature Physics2008，4，： | 1 |
| 8 | Viewpoint Optimization Method for Flying Robot Inspecting Transmission Towers Based on Point Cloud Model显示文摘This paper presents a method to derive optimal viewpoints for flying robot based transmission tower inspection, which applies point cloud model. A safe envelope is established according to safe transmission tower inspection rules. Essential inspection factors are proposed to evaluate the quality of candidate viewpoints, which includes visibility, dimensionality feature of point cloud as well as the distance between viewpoint and transmission power. A score function is constructed to quantify candidate viewpoints, while multiple attribute decision theory is applied to calculate the weight of each factor. Particle swarm optimization(PSO) is used to find the optimal viewpoints set. Both simulation experiment and practical observations are carried out. The results prove that optimal viewpoints have a great contribution for accurate transmission tower inspection. Final results are compared to patch-based method and proved to be feasible. | LIU Chang'an DONG Ruifang JIN Lu WU Hua | 2018 | Chinese Journal of Electronics2018，27，5： | 1 |
| 9 | Detection of survivin expression in cervical cancer cells using molecular beacon imaging: new strategy for the diagnosis of cervical cancer显示文摘 | Yan Xue Ruifang An Dong Zhang Jun Zhao Xinyang Wang Lili Yang Dalin He | 2011 | European Journal of Obstetrics and Gynecology2011，，1： | 1 |
| 10 | Experimental study on the vitrification and xenotransplantation of human ovarian tissue显示文摘Background:Cryopreservation of ovarian tissue is a promising method for preserving fertility.Transmission electron microscopy(TEM)is an evaluation system for cryo-injury during the cooling and warming process which is very laborious and needs to be optimized.Objective:In this study,we evaluated that serum 17β-oestradiol(E2)may be used as an indicator of vitrified ovarian tissue.Methods:Immunodeficient nude mice were used as hosts for xenografting of vitrified-warmed human ovarian tissues.A total of 54 mice were divided into two group:vitrified ovarian xenotransplant(VOX)group(n?45)and non-transplant control group(n?9).The transplanted mice were grouped into vitrified/warmed grafted-4 weeks(VOX-4w,n?15),vitrified/warmed grafted-6weeks(VOX-6w n?15)and vitrified/warmed grafted-12 weeks(VOX-12w n?15)according to the time after transplantation.The viable and functional recovery of grafted ovarian tissue was assessed by light microscopy,transmission electron microscopy,and hormone(E2)assays.Results:Serum E2 concentration was significantly higher in VOX-6w(group(21.07 pg/ml)than that of VOX-12w group(15.59 pg/ml).VOX-12w group showed a lower value(12.61 pg/ml)for E2 concentration.The trend for E2 concentration was consistent with the morphological identification of the grafts.Conclusion:In vivo serum hormone E2 released by cortical biopsies can be used as a functional marker for xenotransplanted vitrified-warmed human ovarian tissue reserve. | Jinghui Zhao Yuping Ge Jingyi Li Yucui Zeng Guoyi Dong Liping Zeng Juanjuan Dai Hui Du Mumin Shao Xuewen Yu Huan Li Fang He Zhouchun Shang Chun Wang Gabor Vajt Huiru Tang Ruifang Wu Yutao Du | 2022 | Gynecology and Obstetrics Clinical Medicine2022，2，1： | 1 |
| 11 | Complex mode superposition algorithm for seismic responses of nonclassically damped linear MDOF system显示文摘 | ZHOU Xiyuan YU Ruifang DONG Di | 2004 | Journal of Earthquake Engineering2004，8，4： | 1 |
| 12 | Complex mode superposition algorithm for seismic response of non- classically damped linear MDOF system显示文摘 | Zhou Xiyuan Yu Ruifang Dong di | 2004 | Journal of Earthquake Engineering2004，8，4： | 1 |
| 13 | Complex mode superpostion algorithm for seismic response of non-classically damped linear MDOF system 显示文摘 | Xiyuan Yu Ruifang Dong Di | 2004 | Journal of Earthquake Engineering2004，8，4： | 1 |
| 14 | Complex mode superposition algorithm for seismic responses of nonclassically damped linear MDOF system显示文摘 | Zhou Xiyuan Yu Ruifang Dong Di | 2004 | Journal of Earthquake Engineering2004，8，4： | 1 |
| 15 | Quantum microwave photonics in radio-over-fiber systems显示文摘As the main branch of microwave photonics,radio-over-fiber technology provides high bandwidth,low-loss,and long-distance propagation capability,facilitating wide applications ranging from telecommunication to wireless networks.With ultrashort pulses as the optical carrier,a large capacity is further endowed.However,the wide bandwidth of ultrashort pulses results in the severe vulnerability of high-frequency radio frequency(RF)signals to fiber dispersion.With a time-energy entangled biphoton source as the optical carrier combined with the singlephoton detection technique,a quantum microwave photonics method in radio-over-fiber systems is proposed and demonstrated experimentally.The results show that it not only realizes unprecedented nonlocal RF signal modulation with strong resistance to the dispersion but also provides an alternative mechanism to distill the RF signal out from the dispersion effectively.Furthermore,the spurious-free dynamic ranges of the nonlocally modulated and distilled RF signals have been significantly improved.With the ultra-weak detection and the high-speed processing advantages endowed by the low-timing-jitter single-photon detection,the quantum microwave photonics method opens new possibilities in modern communication and networks. | YAQING JIN YE YANG HUIBO HONG XIAO XIANG RUNAI QUAN TAO LIU SHOUGANG ZHANG NINGHUA ZHU MING LI RUIFANG DONG | 2022 | Photonics Research2022，10，7： | 0 |
| 16 | Surpassing the classical limit of the microwave photonic frequency fading effect by quantum microwave photonics显示文摘With energy-time entangled biphoton sources as the optical carrier and time-correlated single-photon detection for high-speed radio frequency(RF)signal recovery,the method of quantum microwave photonics(QMWP)has presented the unprecedented potential of nonlocal RF signal encoding and efficient RF signal distilling from the dispersion interference associated with ultrashort pulse carriers.In this paper,its capability in microwave signal processing and prospective superiority are further demonstrated.Both QMWP RF phase shifting and transversal filtering functionality,which are the fundamental building blocks of microwave signal processing,are realized.Besides good immunity to the dispersion-induced frequency fading effect associated with the broadband carrier in classical MWP,a native two-dimensional parallel microwave signal processor is provided.These results well demonstrate the superiority of QMWP over classical MWP and open the door to new application fields of MWP involving encrypted processing. | YAQING JIN YE YANG HUIBO HONG XIAO XIANG RUN'AI QUAN TAO LIU NINGHUA ZHU MING LI SHOUGANG ZHANG RUIFANG DONG | 2023 | Photonics Research2023，11，6： | 0 |
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