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| 1 | Proteomic characteristics of the liver and skeletal muscle in the Chinese tree shrew(Tupaia belangeri chinensis)显示文摘Valid animal models are useful for studying the pathophysiology of specific disorders,such as neural disease,diabetes and cancer.Previous molecular phylogeny studies indicate that the tree shrew is in the same order as(or a close sister to)primates,and thus may be an ideal model in which to study human disease.In this study,the proteome of liver and muscle tissue in tree the shrew was identified by combining peptide fractionation and LC-MS/MS identification.In total,2146 proteins were detected,including 1759 proteins in liver samples and 885 proteins in skeletal muscle samples from the tree shrew.Further sub-source analysis revealed that nearly half of the identified proteins(846 proteins and 418 proteins)were derived from human database.In this study,we are the first to describe the characteristics of the proteome from the liver and skeletal muscle of the tree shrew.Phylogenetic tree analysis based on these proteomic data showed that the tree shrew is closer to primates(human)than to glires(the mouse and rat). | Rongxia Li Wei Xu Zhen Wang Bin Liang Jia-Rui Wu Rong Zeng | 2012 | Protein & Cell2012，3，9： | 18 |
| 2 | Review on supermolecules as chemical drugs显示文摘Supramolecular medicinal chemistry field has been a quite rapidly developing,increasingly active and newly rising interdiscipline which is the new expansion of supramolecular chemistry in pharmaceu-tical sciences,and is gradually becoming a relatively independent scientific area. Supramolecular drugs could be defined as medicinal supermolecules formed by two or more molecules through non-covalent bonds. So far a lot of supermolecules as chemical drugs have been widely used in clinics. Supermolecules as chemical drugs,i.e. supramolecular chemical drugs or supramolecular drugs,which might have the excellences of lower cost,shorter period,higher potential as clinical drugs for their successful research and development,may possess higher bioavailability,better biocompatibility and drug-targeting,fewer multidrug-resistances,lower toxicity,less adverse effect,and better curative effects as well as safety,and therefore exhibit wide potential application. These overwhelming advan-tages have drawn enormous special attention. This paper gives the definition of supramolecular drugs,proposes the concept of supramolecular chemical drugs,and systematically reviews the recent ad-vances in the research and development of supermolecules,including organic and inorganic complex ones as chemical drugs in the area of antitumor,anti-inflammatory,analgesic,antimalarial,antibacterial,antifungal,antivirus,anti-epileptic,cardiovascular agents and magnetic resonance imaging agents and so on. The perspectives of the foreseeable future and potential application of supramolecules as chemical drugs are also presented. | ZHOU ChengHe GAN LinLing ZHANG YiYi ZHANG FeiFei WANG GuangZhou JIN Lei GENG RongXia | 2009 | Science China Chemistry2009，52，4： | 17 |
| 3 | Assessing the numbers of SNPs needed to establish molecular IDs and characterize the genetic diversityof soybean cultivars derived from Tokachi nagaha显示文摘The development of a core set of SNP molecular markers that could be widely used in soybean genetic research would greatly facilitate research into the genetic diversity of soybean.We conducted an analysis of Tokachi nagaha and 137 of its descendant soybean cultivars using 4044 SNP markers with the goal of determining the appropriate number of single-nucleotide polymorphisms(SNPs)needed to construct unambiguous molecular IDs and characterize genetic diversity based on a genetic distance matrix correlation method.When the number of SNPs was held constant,the number of accession pairs that could be distinguished increased as the polymorphism informative content(PIC)value of the SNPs increased.A core panel of 20 selected SNPs from 11 linkage groups with a mean PIC value of 0.3703 and a range of 0.3640–0.3749 was able to identify almost all of the accession pairs in our study[9445 pairs(99.92%)].The eight accession pairs that could not be identified with this core SNP set all originated from the same province and some of them had the same parental cultivars.The molecular IDs of the 138 accessions were constructed using the core 20 SNPs.It is known that both the number of SNPs and PIC values should be considered when SNPs are selected for use in the analysis of genetic diversity.In this study,when the PIC value was 0.3460,the correlation coefficient between the genetic distance matrices associated with a panel of 200 SNPs and the total population was>0.800,indicating satisfactory correlation.Our high-accuracy,high-resolution core SNP panel for germplasm fingerprinting and our findings about assessing genetic diversity will likely markedly improve the management and utilization efficiency of soybean germplasm resources. | Zhangxiong Liu Jun Li Xuhong Fan Nang Myint Phyu Sin Htwe Shuming Wang Wen Huang Jiyu Yang Lili Xing Lijun Chen Yinghui Li Rongxia Guan Ruzhen Chang Dechun Wang Lijuan Qiu | 2017 | The Crop Journal2017，5，4： | 10 |
| 4 | Development and utilization of a new chemically-induced soybean library with a high mutation density显示文摘Mutagenized populations have provided important materials for introducing variation and identifying gene function in plants. In this study, an ethyl methanesulfonate(EMS)-induced soybean(Glycine max) population,consisting of 21,600 independent M_2 lines, was developed.Over 1,000 M_(4(5))families, with diverse abnormal phenotypes for seed composition, seed shape, plant morphology and maturity that are stably expressed across different environments and generations were identified. Phenotypic analysis of the population led to the identification of a yellow pigmentation mutant, gyl, that displayed significantly decreased chlorophyll(Chl) content and abnormal chloroplast development. Sequence analysis showed that gyl is allelic to Minn Gold, where a different single nucleotide polymorphism variation in the Mg-chelatase subunit gene(ChlI1a) results in golden yellow leaves. A cleaved amplified polymorphic sequence marker was developed and may be applied to marker-assisted selection for the golden yellow phenotype in soybean breeding. We show that the newly developed soybean EMS mutant population has potential for functional genomics research and genetic improvement in soybean. | Zhongfeng Li Lingxue Jiang Yansong Ma Zhongyan Wei Huilong Hong Zhangxiong Liu Jinhui Lei Ying Liu Rongxia Guan Yong Guo Longguo Jin Lijuan Zhang Yinghui Li Yulong Ren Wei He Ming Liu Nang Myint Phyu Sin Htwe Lin Liu Bingfu Guo Jian Song Bing Tan Guifeng Liu Maiquan Li Xianli Zhang Bo Liu Xuehui Shi Sining Han Sunan Hua Fulai Zhou Lili Yu Yanfei Li Shuang Wang Jun Wang Ruzhen Chang Lijuan Qiu | 2017 | Journal of Integrative Plant Biology2017，59，1： | 6 |
| 5 | Co-regulation of indole glucosinolates and camalexin biosynthesis by CPK5/CPK6 and MPK3/MPK6 signaling pathways^°°显示文摘Secondary plant metabolites,represented by indole glucosinolates(IGS)and camalexin,play important roles in Arabidopsis immunity.Previously,we demonstrated the importance of MPK3 and MPK6,two closely related MAPKs,in regulating Botrytis cinerea(Bc)-induced IGS and camalexin biosynthesis.Here we report that CPK5 and CPK6,two redundant calcium-dependent protein kinases(CPKs),are also involved in regulating the biosynthesis of these secondary metabolites.The loss-of-function of both CPK5 and CPK6 compromises plant resistance to Be.Expression profiling of CPK5-VK transgenic plants,in which a truncated constitutively active CPK5 is driven by a steroidinducible promoter,revealed that biosynthetic genes of both IGS and camalexin pathways are coordinately upregulated after the induction of CPK5-VK,leading to high-level accumulation of camalexin and 4-methoxyindole-3-ylmethylglucosinolate(4MI3G).Induction of camalexin and 4MI3G,as well as the genes in their biosynthesis pathways,is greatly compromised in cpks cpk6 mutant in response to Be.In a conditional cpk5 cpk6 mpk3 mpk6 quadruple mutant,Be resistance and induction of IGS and camalexin are further reduced in comparison to either cpks cpk6 or conditional mpk3 mpk6 double mutant,suggesting that both CPK5/CPK6 and MPK3/MPK6 signaling pathways contribute to promote the biosynthesis of 4MI3G and camalexin in defense against Be. | Liuyi Vang Yan Zhang Rongxia Guan Sen Li Xuwen Xu Shuqun Zhang Juan Xu | 2020 | Journal of Integrative Plant Biology2020，62，11： | 6 |
| 6 | Mapping and validation of a dominant salt tolerance gene in the cultivated soybean(Glycine max) variety Tiefeng 8显示文摘Salt is an abiotic stress factor that strongly affects soybean growth and production. A single dominant gene has been shown to confer salt tolerance in the soybean cultivar Tiefeng 8.The objective of the present study was to genetically map the salt-tolerance gene in an F2:3population and a recombinant inbred line(RIL) population derived from a cross between two cultivated soybeans, Tiefeng 8(tolerant) and 85-140(sensitive). The F2:3families and RILs were treated with 200 mmol L-1Na Cl to evaluate salt tolerance. The F2:3population showed 1(42 tolerant): 2(132 segregating): 1(65 sensitive) segregation, indicating a single dominant gene for salt tolerance in Tiefeng 8. A sequence-characterized amplified region(SCAR) marker from a previously identified random amplified polymorphic DNA(RAPD)marker and four insertion/deletion polymorphism(In Del) markers were developed within the mapping region. Using these markers along with SSR markers, the salt-tolerance gene was mapped within 209 kb flanked by SCAR marker QS08064 and SSR marker Barcsoyssr_3_1301 on chromosome 3. Three markers that cosegregated with the salt tolerance gene and SCAR marker QS08064 were used to genotype 35 tolerant and 23 sensitive soybean accessions. These markers showed selection efficiencies of 76.2% to94.2%. The results indicate that these markers will be useful for marker-assisted breeding and facilitating map-based cloning of the salt tolerance gene in soybean. | Rongxia Guan Jiangang Chen Jinghan Jiang Guangyu Liu Ying Liu Lei Tian Lili Yu Ruzhen Chang Li-juan Qiu | 2014 | The Crop Journal2014，2，6： | 5 |
| 7 | Molecular characterization of GmNHX2,a Na^+/H^+ antiporter gene homolog from soybean,and its heterologous expression to improve salt tolerance in Arabidopsis显示文摘Na+/H+ antiporters have been well documented to enhance plant salt tolerance by regulating cellular ion homeostasis. Here, a putative Na+/H+ antiporter gene homolog GmNHX2 from soybean was cloned and predicted to encode a protein of 534 amino acids with 10 putative transmembrane domains. GmNHX2 was expressed in all soybean plant tissues but enriched in roots and its expression was induced by NaCl and polyethylene glycol (PEG) treatments. GmNHX2 exhibits greater sequence similarity with LeNHX2 and AtNHX6 than that of AtNHX1 and AtSOS1. Although phylogenetic analysis clustered GmNHX2 with organellar (tonoplast and vesicles) antiporters, the GmNHX2-EGFP (enhanced green fluorescent protein) fusion protein was possibly localized in the plasma membrane or organelle membrane of transgenic plant cells. Furthermore, transgenic Arabidopsis plants expressing GmNHX2 were more tolerant to high NaCl concentrations during germination and seedling stages when compared with wild-type plants. These results suggest that GmNHX2 is a membrane Na+/H+ antiporter and may function to regulate ion homeostasis under salt stress. | ZHOU GuoAn GUAN RongXia LI YingHui CHANG RuZhen QIU LiJuan | 2009 | Chinese Science Bulletin2009，54，19： | 4 |
| 8 | Genetic contribution of foreign germplasm to elite Chinese soybean (Glycine max) cultivars revealed by SSR markers显示文摘Simple sequence repeats (SSR) marker analysis, combined with pedigree analysis, was car- ried out to trace the genetic constitutes of Suinong 14 and Hefeng 25 in assessing the contribution of for- eign germplasm to those elite cultivars. The overall goal is to accumulate information for further effective utilization of foreign germplasm in Chinese soybean breeding programs. SSR clustering results indicated that the genetic base of elite Chinese soybean culti- vars, including Suinong 14 and Hefeng 25, were broadened and enhanced via introduction of Amsoy from the U.S. and Shishengchangye from Japan. The pedigree analysis showed a very high coefficient of parentage between Shishengchangye and Hefeng 25, between Shishengchangye and Suinong 14, and between Amsoy and Suinong 14. The genetic simi- larity between Suinong 14 and Hefeng 25 was 60.58%. Among 20 linkage groups, more genomic regions were transferred from Hefeng 25 to Suinong 14 in linkage group (LG) I, L and C2 than other LGs. Among the unique alleles of foreign parents, five specific loci in Amsoy were transferred to Suinong 14, and three loci from Shishengchangye to Suinong 14. Some SSR loci were proved to be correlated with phenotypes: two loci for seed size introgressed from Shishengchangye to Suinong 14, and one locus forprotein content from Amsoy to Suinong 14. These results indicate that the two foreign parents might have important contributions in the development of Suinong 14 and Hefeng 25. | QIN Jun CHEN Weiyuan GUAN Rongxia JIANG Chengxi LI Yinghui FU Yashu LIU Zhangxiong ZHANG Mengchen CHANG Ruzhen QIU Lijuan | 2006 | Chinese Science Bulletin2006，51，9： | 4 |
| 9 | The genus polynomials of cross-ladder digraphs in orientable surfaces显示文摘Some results about the genus distributions of graphs are known,but little is known about those of digraphs.In this paper,the method of joint trees initiated by Liu is generalized to compute the embedding genus distributions of digraphs in orientable surfaces.The genus polynomials for a new kind of 4-regular digraphs called the cross-ladders in orientable surfaces are obtained.These results are close to solving the third problem given by Bonnington et al. | HAO RongXia LIU YanPei | 2008 | Science China Mathematics2008，51，5： | 3 |
| 10 | Molten Salt Electrolytic Fabrication of TiC-CDC and Its Applications for Supercapacitor显示文摘Titanium carbide derived carbon(TiC-CDC) was prepared by the molten salt electrolytic method in molten salt NaCl–KCl at the potential of 1.3 V using TiC pellets as the anode. X-ray diffraction, scanning electron microscopy and Raman spectrum were used to characterize the composition, morphology and microstructure of TiC-CDC. The electrochemical performance of TiC-CDC for supercapacitor was investigated in 0.5 mol L^(-1)Na_2SO_4 by cycle voltammograms, ac impedance spectrum and galvanostatic charge/discharge. TiC-CDC showed excellent electrochemical and capacitive performances and maintained a capacity value of 126.1 F g^(-1)after 1000 cycles with a capacity retention rate of 97% at the current density of 3 Ag^(-1). The current work demonstrated the feasibility of molten salt electrolytic method for preparation of TiC-CDC and provided a non-polluting and environmentally friendly strategy for high performance supercapacitor fabrication. | Chaopin Wan Rongxia Zhang Shulan Wang Xuan Liu | 2017 | Journal of Materials Science & Technology2017，33，8： | 2 |
| 11 | Baf60b-mediated ATM-p53 activation blocks cell identity conversion by sensing chromatin opening显示文摘由系特定的抄写因素的表示的系变换是改变那的 epigenetic 的进程有低效率。一个房间由抵抗系变换的机制大部分是未知的。使用肝特定的抄写因素 Foxa3, Hnf1 和 Gata4 (3TF ) 在老鼠成纤维细胞导致肝的变换,我们证明 3TF 导致了 ATM-p53 小径的强壮的激活,它导致了增长拘捕和房间死亡,和它进一步阻止了肝的变换。尤其是, ATM 激活,独立于 DNA 损坏,对染色质在肝的变换期间开作出回应。由在肝的变换期间描绘早分子的事件,我们发现了那 Baf60b,改变建筑群的 SWI/SNF 染色质的一个成员,连接染色质洞到由便于 ATM 招募到肝的基因 loci 的一块面板的开的染色质区域的 ATM 激活。这些调查结果由在察觉到揭示 ATM-p53 小径的功能使细胞的回答清楚些到系变换染色质洞。 | Shuyi Ji Linying Zhu Yimeng Gao Xiaoran Zhang Yupeng Yan Jin Cen Rongxia Li Rong Zeng Lujian Liao Chunhui Hou Yawei Gao Shaorong Gao Gang Wei Lijian Hui | 2017 | Cell Research2017，27，5： | 2 |
| 12 | Quantitative analysis of secretome from adipocytes regulated by insulin显示文摘Adipocyte 是经由肽和蛋白质的分泌物在另外的机关涉及精力的存储和版本,而且在精力新陈代谢的规定的不仅一个中央播放器。在胰岛素抵抗和类型的致病期间 2 糖尿病, adipocytes 受到胰岛素的增加的层次,它可以在 adipokines 的分泌物上有主要影响。我们承担了劈得开的编码同位素的亲密关系标签(cICAT ) ,没有标签的 quantitation 来临鉴别是差别的能分泌的因素由 3T3-L1 adipocytes 藏匿了与或没有胰岛素处理并且确定。cICAT 和没有标签的结果的联合,有 317 蛋白质,预言或注解同样能分泌的蛋白质。在这些能分泌的蛋白质之中, 179 蛋白质和 53 蛋白质分别地显著地起来调整、下面调整。77 的一个总数报导 adipokines 在我们的学习被确定,例如 adiponectin,组织蛋白酶 D, cystatin C, resistin,和 transferrin。这些 adipokines 的西方的污点分析从集体 spectrometry 证实了量的结果,并且由增加胰岛素剂量揭示了这些蛋白质的个性化的 secreting 模式。另外, 240 蛋白质是在我们的学习,其大多数在胰岛素处理之上起来调整从 3T3-L1 adipocytes 分泌了蛋白质最新被识别并且确定。进一步全面的生物信息学分析表明在细胞外的矩阵受体相互作用小径和 glycan 结构降级小径的能分泌的蛋白质由胰岛素刺激是显著地起来调整的。 | Hu Zhou Yuanyuan Xiao Rongxia Li Shangyu Hong Sujun Li Lianshui Wang Rong Zeng Kan Liao | 2009 | Acta Biochimica et Biophysica Sinica2009，41，11： | 2 |
| 13 | Deep genotyping of the gene GmSNAP facilitates pyramiding resistance to cyst nematode in soybean显示文摘Soybean cyst nematode(SCN)is a highly destructive pathogen.The soybean host genome harbors at least two major genes for resistance(rhg1 and Rhg4),as well as a minor locus(SCN3-11).In the present study,a splicing site in GmSNAP11,the potential causal gene of SCN3-11,was identified by comparison of the GmSNAP11 cDNA sequences generated from resistant and susceptible soybean accessions.The sequence information was used to design a codominant CAPS marker,GmSNAP11-2565,which was used to genotype a panel of 209 soybean accessions varying with respect to SCN resistance.Analyses of the effect of the haplotypes formed by GmSNAP11-2565 and another large-effect(nonsynonymous)locus,GmSNAP11-2307,previously identified in GmSNAP11,revealed linkage disequilibrium(P<0.0001)between the two loci,suggesting that GmSNAP11-2565 could be used as a marker for GmSNAP11.GmSNAP11-2565 was accordingly used,along with established markers for GmSNAP18(rhg1)and GmSHMT(Rhg4),to characterize the panel accessions.The mean SCN female index of accessions carrying only the GmSNAP11 allele associated with resistance(20.3%)was higher than that associated with accessions carrying alleles for resistance at both GmSNAP11 and GmSNAP18(12.4%),while the index for accessions carrying alleles for resistance at all of GmSNAP11,GmSNAP18,and GmSHMT was very low(1.9%).Selection on all three markers was effective for maintaining a high level of resistance to SCN race 3. | Yu Tian Bo Liu Xuehui Shi Jochen C.Reif Rongxia Guan Ying-hui Li Li-juan Qiu | 2019 | The Crop Journal2019，7，5： | 2 |
| 14 | High‐performance ZnO varistor ceramics prepared by arc‐induced flash sintering with low energy consumption at room temperature显示文摘The development of ultra‐high voltage transmission lines requires a ZnO arrester with excellent electrical response and high voltage gradient.Compared with conventional preparation methods,flash sintering allows fast production of novel high‐performance ZnO varistor ceramics with low energy consumption and controlled grain growth.Herein,ZnO varistor ceramics were prepared using the flash sintering method at an air pressure of 21 kPa for 60 s at 25℃.The results showed that the flash‐sintered samples had fine grains and reduced loss of volatile elements.Moreover,the voltage gradient,leakage current density,and non‐linear coefficient of the flash‐sintered varistor ceramics were significantly improved compared with those of conventionally sintered samples.Owing to the short preparation time and absence of a heating process,the energy consumption of the proposed flash sintering method was significantly reduced to 10%of that by conventional sintering.The proposed method is a promising approach for the preparation of ZnO arresters with excellent electrical properties and serves as an effective method that realises energy saving and emission reduction. | Angxuan Wu Zhixiang Zhu Xilin Wang Nianping Yan Hongyang Zhou Rongxia Huang Guoming Ma Zhidong Jia Liming Wang | 2022 | High Voltage2022，7，2： | 2 |
| 15 | Simultaneous LC determination of major constituents in red and white peony root 显示文摘 | Wang Qiao Liu Rongxia Guo Hongzhu | 2005 | Chromatographia2005，62，1112： | 1 |
| 16 | Genome-wide signatures of the geographic expansion and breeding of soybean显示文摘Soybean is a leguminous crop that provides oil and protein. Exploring the genomic signatures of soybean evolution is crucial for breeding varieties with improved adaptability to environmental extremes. We analyzed the genome sequences of 2,214 soybeans and proposed a soybean evolutionary route, i.e., the expansion of annual wild soybean(Glycine soja Sieb. & Zucc.) from southern China and its domestication in central China, followed by the expansion and local breeding selection of its landraces(G. max(L.) Merr.). We observed that the genetic introgression in soybean landraces was mostly derived from sympatric rather than allopatric wild populations during the geographic expansion. Soybean expansion and breeding were accompanied by the positive selection of flowering time genes, including GmSPA3c. Our study sheds light on the evolutionary history of soybean and provides valuable genetic resources for its future breeding. | Ying-Hui Li Chao Qin Li Wang Chengzhi Jiao Huilong Hong Yu Tian Yanfei Li Guangnan Xing Jun Wang Yongzhe Gu Xingpeng Gao Delin Li Hongyu Li Zhangxiong Liu Xin Jing Beibei Feng Tao Zhao Rongxia Guan Yong Guo Jun Liu Zhe Yan Lijuan Zhang Tianli Ge Xiangkong Li Xiaobo Wang Hongmei Qiu Wanhai Zhang Xiaoyan Luan Yingpeng Han Dezhi Han Ruzhen Chang Yalong Guo Jochen C.Reif Scott A.Jackson Bin Liu Shilin Tian Li-juan Qiu | 2023 | Science China(Life Sciences)2023，66，2： | 1 |
| 17 | A water-free metal organic deposition method for YBa2Cu3O7?δ thin film fabrication显示文摘 | Rongxia Huang Feng Feng Wei Wu Yunran Xue Yanyi Zhang Kai Shi Timing Qu Yongjie Zhao Xiaohao Wang Xiaowen Zhang Zhenghe Han | 2013 | Superconductor Science and Technology2013，，： | 1 |
| 18 | Research of relieving anxiety and improve performance of entrance examination for college with progressive relaxation and abdominal training显示文摘 | ZHAO Rongxia LI Yinghui YAN Kele | 2003 | Healthy Psychology Journal2003，11，4： | 1 |
| 19 | Analysis on Shearing Deformation of Sectional Joints Affecting De- flection of Cantilever Constructed Box Girder 显示文摘 | Wang Rongxia Li Hongjiang Kexi Jin | 2011 | Ad- vanced Materials Research2011，，： | 1 |
| 20 | Chalcone-Benzotriazole Conjugates as New Potential Antimicrobial Agents: Design, Synthesis, Biological Evaluation and Synergism with Clinical Drugs显示文摘当新潜在的抗菌剂代理人被 1 H NMR, 13 C NMR,红外和 HRMS 系列。抗菌剂试金表明了目标混合物给了的那一些对好抗菌剂和抗真菌的活动中等。N-1 导出 benzotriazole 5e, N-2 导出对测试的一些的展出珍贵禁止的功效拉紧的 benzotriazole 6a。特别,衍生物 6a 对 C 给了优异抗真菌的功效。utilis, S。cerevisiae 和 A。flavus (MIC=0.01, 0.02, 0.02biguity,和在感情方面、支持的亲戚关系关系中产生的紧张的焦点,还也开发资源。主要争论是有 precarity ,和那种亲戚关系的不同模式,哪个主要在一个不明确的世界上被认为是安全,吗能事实上加重动荡的 condition.Lentrepreneuriat pr 賦?觧???铧????釦?觧???藦??藦????賧??????闧?闦?蓦?觧???? 吗?? | Hanbo Liu Lavanya Gopala Srinivasa Rao Avula Ponmani Jeyakkumar Xinmei Peng Chenghe Zhou Rongxia Geng | 2017 | Chinese Journal of Chemistry2017，35，4： | 1 |
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