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| 1 | Distribution of IgG galactosylation as a promising biomarker for cancer screening in multiple cancer types显示文摘 | Shifang Ren Zejian Zhang Congjian Xu Lin Guo Renquan Lu Yihong Sun Jianming Guo Ruihuan Qin Wenjun Qin Jianxin Gu | 2016 | Cell Research2016，26，8： | 8 |
| 2 | Curative effect of Xuebijing injection on severe pulmonary contusion显示文摘OBJECTIVE: To investigate the curative effects of Xuebijing(XBJ) injection, a Chinese patent medicine, on severe pulmonary contusion(PC). METHODS: Sixty-three patients with PC were randomized to conventional therapy plus XBJ injection(n=33) or conventional therapy alone(n=30). Between groups differences in corticosteroid treatment, immune regulation therapy, hemofiltration, infusion volume, transfusion volume and antibiotic period were measured, as were intensive care unit (ICU)-free time, ventilation time, 28-day mortality rate and incidence of ventilation-associated pneumonia(VAP). Serum concentrations of procalcitonin(PCT), tumor necrosis factor-α(TNF-α), interleukin(IL)-6, and IL-10, white blood cell(WBC) counts and percentages of human leukocyte antigen DR/ CD14+(HLA-DR/CD14+) peripheral blood mononuclear cells were compared. Markers of ventilation were determined by blood gas analysis and ventilator parameters. RESULTS: WBC counts and serum concentrations of PCT, TNF-α, IL-6 and IL-10 were reduced significantly more quickly, and CD14+ percentage was increased significantly earlier, in the XBJ group than in the control group(P<0.05 each).The level of ventilation and oxygenation index were ameliorated earlier in the XBJ than in the control group(P< 0.05). XBJ treatment significantly reduced ICU-stay time, ventilation time and incidence of VAP(P<0.05 each), but had no effect on 28-day mortality rate(P>0.05). CONCLUSION: XBJ treatment can shorten ICU-free and ventilation times and reduce the incidence of VAP, improving outcomes in patients with severe PC. XBJ may act by regulating inflammation and immunity, alleviating systemic inflammatory response syndrome induced by trauma. | Yi Chen Huasheng Tong Wang Zhang Xingqin Zhang Zhigguo Pan Junming Qiu Ruihuan Pan Lei Su | 2013 | Journal of Traditional Chinese Medicine2013，33，6： | 6 |
| 3 | Research Status and Progress on Modification of Dietary Fiber at Home and Abroad显示文摘Studies have shown that modified dietary fiber has better physical and chemical properties and functions,and can better play its physiological effects.This paper systematically and comprehensively expounded the application progress of chemical separation method,microbial fermentation method,physical method,enzyme method and steam explosion method in dietary fiber modification,and expounded the development prospect of modified dietary fiber,so as to provide reference for further study on development and application of dietary fiber. | Xiaoran DUAN Suyan GAO Shoumin JIA Litian ZHANG Ruihuan DU Aili XIANG Biao QI Lei WANG | 2019 | Agricultural Biotechnology2019，8，4： | 5 |
| 4 | One-pot synthesis of Li_3VO_4@C nanofibers by electrospinning with enhanced electrochemical performance for lithium-ion batteries显示文摘Electrospinning is firstly used to one-pot synthesis of Li_3VO_4@C nanofibers in a large scale. Although with the presence of organic sources in synthesis process, the pure phase Li_3VO_4 with superior nanofibrous morphology is still successfully obtained through adjusting different heat treatment processes and different vanadium sources. The prepared Li_3VO_4@C nanofibers exhibit a unique structure in which nanosized Li_3VO_4 particles are uniformly embedded in amorphous carbon matrix. Compared with Li_3VO_4/C powder,Li_3VO_4@C nanofibers display enhanced reversible capacity of 451 mAh g^(-1)at 40 mAg^(-1)with an increased initial coulombic efficiency of 82.3%, and the capacity can remain at 394 m Ah g^(-1)after 100 cycles. This superior electrochemical performance can be attributed to its unique structure which ensures a high reactivity by nanosized Li_3VO_4, more stable electrode/electrolyte interface by carbon encapsulation, improved electronic conductivity and buffered volume changes by flexible carbon matrix. The electrospinning technology provides an effective method to obtain high performance Li_3VO_4 as a promising anode material for lithium-ion batteries. | Ruihuan Qin Gaoqi Shao Junxian Hou Zhi Zheng Tianyou Zhai Huiqiao Li | 2017 | Science Bulletin2017，62，15： | 5 |
| 5 | Influence of metal ions on sulfonamide antibiotics biochemical behavior in fiber coexisting system显示文摘Metal ions and fiber are common compounds in the livestock and poultry manure,which will affect the fate of organic compounds in aqueous environment. However,limited research has addressed the effect of coexisting metal ions and fiber on the biodegradation of sulfonamide antibiotics. Accordingly, a compositing study was performed to assess the effect of metal ions(Fe3+and Cu2+) on the biodegradation of sulfadimethoxine sodium salt(SDM) in the presence of fiber. The enhanced adsorption of SDM onto fiber in the presence of metal ions can be attributed to the π+–π electron donor acceptor(EDA) interaction. The microbial(Phanerochaete chrysosprium) could easily attach onto fiber forming attached microbial, and the degradation rates of SDM of immobilized bacteria in the presence of Fe3 +were 100%, which were significantly higher than those of free bacteria(45%). This study indicates that Fe3 +and fiber could enhance the biodegradation of SDM. Fiber acts as adsorbent, carrier, and substrate which enhanced the removal of SDM. | Lan Zhang Ruihuan Chen Yun Liu Youjun Deng Zhongpei Li Yuanhua Dong | 2019 | Journal of Environmental Sciences2019，31，6： | 3 |
| 6 | Identification of Histoplasma causing an unexplained disease cluster in Matthews Ridge, Guyana显示文摘Here,we report the identification of Histoplasma causing an unexplained disease cluster in Matthews Ridge,Guyana.In March 2019,14 employees of Chongqing Bosai Mining Company,China,working in a manganese mining of Guyana,had unexplained fever,and two of them died.We obtained lung and brain tissues as well as the blood samples from the two deceased cases(patient No.1 and 2),and bronchoscopy lavages and cerebrospinal fluid samples from one severe case(patient No.3),respectively.All samples were tested by pathological examination,high-throughput sequencing,and real-time PCR.Pathological detection showed the presence of spore-like structures in the lung tissue of patient No.1,indicating a fungal infection in this patient.Nanopore sequencing identified the existing of H.capsulatum in the lung tissue sample within 13 h.Next-generation sequencing identified specific fragments of H.capsulatum in all of the samples tested(lung,brain and blood serum from the deceased cases,and plasma from the severe case).Real-time PCR assays did not reveal any viral infection related to transmission from bat feces.We conclude that H.capsulatum was the causative pathogen of this disease cluster based on epidemiologic,clinical,pathological and nucleic acid evidence. | Ji Wang Weimin Zhou Hua Ling Xiaoping Dong Yi Zhang Jiandong Li Yong Zhang Jingdong Song William J.Liu Yang Li Ruiqing Zhang Wei Zhen Kun Cai Shuangli Zhu Dongyan Wang Jinbo Xiao Yigang Tong Wenli Liu Lihua Song Wei Wu Yang Liu Xiang Zhao Ruihuan Wang Sheng Ye Jing Wang Roujian Lu Baoying Huang Fei Ye Wenwen Lei Rongbao Gao Qi Shi Cao Chen Jun Han Wenbo Xu George F.Gao Xuejun Ma Guizhen Wu | 2019 | Biosafety and Health2019，1，3： | 3 |
| 7 | Influencing Factors and Biological Control of Aflatoxin Contamination in Peanuts显示文摘Peanut is an important economic crop and oil crop in China. It is vulnerable to infection by Aspergillus flavus during production,storage,transportation and processing,causing aflatoxin( AFT) contamination. This paper introduced the status and characteristics of AFT contamination in China,analyzed the infection pathways and influencing factors of A. flavus,and discussed the prevention and control technology of AFT contamination in peanuts from the view of the use of beneficial microorganisms. | ruihuan du yi zhang yanpo yao | 2018 | Agricultural Biotechnology2018，7，2： | 2 |
| 8 | Catalytic ozonation of p-chlorobenzoic acid in aqueous solution using Fe-MCM-41 ascatalyst显示文摘 | Lan Bingyan Huang Ruihuan Li Laisheng | 2013 | Chemical Engineering Journal2013，219，： | 1 |
| 9 | The phosphorus cycle in the Sanggou Bay显示文摘The phosphorus cycle is studied during 2013–2014 in the Sanggou Bay(SGB), which is a typical aquaculture area in northern China. The forms of measured phosphorus include dissolved inorganic phosphorus(DIP), dissolved organic phosphorus(DOP), particulate inorganic phosphorus(PIP), and particulate organic phosphorus(POP).DIP and PIP are the major forms of total dissolved phosphorus(TDP) and total particulate phosphorus(TPP),representing 51%–75% and 53%–80%, respectively. The concentrations and distributions of phosphorus forms vary among seasons relative to aquaculture cycles, fluvial input, and hydrodynamic conditions. In autumn the concentration of DIP is significantly higher than in other seasons(P<0.01), and higher concentrations are found in the west of the bay. In winter and spring the phosphorus concentrations are higher in the east of the bay than in the west. In summer, the distributions of phosphorus forms are uniform. A preliminary phosphorus budget is developed, and shows that SGB is a net sink of phosphorus. A total of 1.80×10~7 mol/a phosphorus is transported into the bay. The Yellow Sea is the major source of net input of phosphorus(61%), followed by submarine groundwater discharge(SGD)(27%), river input(11%), and atmospheric deposition(1%). The main phosphorus sink is the harvest of seaweeds(Saccharina japonica and Gracilaria lemaneiformis), bivalves(Chlamys farreri),and oysters(Crassostrea gigas), accounting for a total of 1.12×10~7 mol/a. Burial of phosphorus in sediment is another important sink, accounting for 7.00×10~6 mol/a. Biodeposition by bivalves is the major source of phosphorus in sediment, accounting for 54% of the total. | XU Wenqi LI Ruihuan LIU Sumei NING Zhiming JIANG Zengjie | 2017 | Acta Oceanologica Sinica2017，36，1： | 1 |
| 10 | Carbon-to-chlorophyll ratio and carbon content of phytoplankton community at the surface in coastal waters adjacent to the Zhujiang River Estuary during summer显示文摘Chlorophyll a(Chl a),particulate organic carbon(POC)and biogenic silica(BSi)were determined in coastal waters adjacent to the Zhujiang(Pearl)River Estuary(ZRE)during summer,in order to examine the C:Chl a ratio of phytoplankton and phytoplankton carbon in the plume-impacted coastal waters during summer,as well as to assess the relative contribution of diatoms to the phytoplankton biomass,by the regression between Chl a,POC and BSi.Our results showed that the C:Chl a ratio(g/g)of phytoplankton was high(up to 142),likely due to high light intensity and nutrient limitation.The river plume input stimulated phytoplankton growth,especially diatoms,resulting in higher relative contribution of phytoplankton carbon(55%)and diatoms(34%)to POC in the plume-impacted region than those(33%and 13%)in high salinity area,respectively.Phytoplankton carbon(up to 538μg/L)in the plume-impacted region was much higher than that(<166μg/L)in high salinity area.Our findings were helpful to improve the biogeochemical model in coastal waters adjacent to the ZRE. | Xiaoyong Yu Jie Xu Aimin Long Ruihuan Li Zhen Shi Qian P Li | 2020 | Acta Oceanologica Sinica2020，39，2： | 1 |
| 11 | Study on Functional and Structure Properties of Soluble Dietary Fiber Modified by Extrusion-expansion Technology from Peanut Shells显示文摘[Objectives] This study was conducted to investigate the feasibility of using modified peanut dietary fiber as a functional food ingredient. [Methods]Using peanut shells as a test material,the process parameters of soluble dietary fiber( SDF) modified by extrusion and expansion were studied,and the functional and structural characteristics of SDF before and after modification were discussed. [Results] The optimum conditions were as follows: screw speed 200 rpm,temperature 130 ℃ and moisture content 20 %,and the SDF extraction yield was 22. 3%. The modified SDF showed BCmax values of( 378. 5 ± 5. 3),( 278. 3 ± 3. 2)and( 167. 2 ± 2. 5) μmol/g and BCmin of( 30. 4 ± 1. 3),( 63. 4 ± 3. 7) and( 71. 3 ± 4. 2) μmol/L,for Pb,As and Cu,respectively,indicating that the adsorption to the three heavy metals was enhanced. The modified SDF had a porous network like honeycomb and swelled structure. [Conclusions]Therefore,it is feasible to modify SDF by extrusion and expansion. | Xishuang XING Lixin QIANG Shuling SUN Xin ZHOU Ruihuan DU Yang LIU Zhe MENG Miaoshu WANG Weili ZHENG Lei WANG Xueying TANG | 2020 | Agricultural Biotechnology2020，9，3： | 1 |
| 12 | Construction of high-efficiency CoS@Nb_(2)O_(5) heterojunctions accelerating charge transfer for boosting photocatalytic hydrogen evolution显示文摘The random movement and easy recombination of photoinduced charges lead to a low conversion efficiency for photocatalytic hydrogen evolution.The cocatalyst design is a promising route to address such problem through introducing an appropriate cocatalyst on the semiconductor photocatalysts to construct the high-efficiency heterojunctions.Herein,novel CoS/Nb_(2)O_(5) heterojunctions were constructed via in-situ loading CoS cocatalyst on the surface of Nb_(2)O_(5) nanosheets.Through the femtosecond-resolved transient absorption spectroscopy,the average lifetime of charge carriers for 10 wt% CoS/Nb_(2)O_(5)(159.6 ps)is drastically shortened by contrast with that of Nb_(2)O_(5)(5531.9 ps),strongly suggesting the rapid charge transfer from Nb_(2)O_(5) to CoS.The significantly improved charge-transfer capacity contributes to a high photocatalytic hydrogen evolution rate of 355µmol/h,up to 17.5 times compared with pristine Nb_(2)O_(5).This work would provide a new design platform in the construction of photocatalytic heterojunctions with high charge-transfer efficiency. | Xin Ren Jianyou Shi Ruihuan Duan Jun Di Chao Xue Xiao Luo Qing Liu Mengyang Xia Bo Lin Wu Tang | 2022 | Chinese Chemical Letters2022，33，10： | 1 |
| 13 | Pharmacological Studies of Meisoindigo: Absorption and Mechanism of Action显示文摘Meisoindigo, an indirubin derivative, is a new type of cancer chemotherapeutic agent. It exhibited higher activity against rodent tumors than indirubin itself. Experiments have shown the improved absorption of meisoindigo, compared to indirubin to be one of the major reasons for the enhancement of antitumor activity. Studies on the mechanism of meisoindigo action indicate that it strongly inhibits DNA biosynthesis in tumor cells. Strong inhibition of the drug on assembly of microtubule protein was also obtained. By means of FCM technique the effects of meisoindigo on mouse leukemia L1210 cell cycle were examined. Experimental results showed that under the action of meisoindigo the S phase cells accumulated and the traverse of the cells in G_2+M phase to G_1 phase may also be blocked to some extent. | Jl XlUJUAN, LIU XIAOMEI, LI KUN, CHEN RUIHUAN, AND WANG LONGGUIInstitute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China. | 1991 | Biomedical and Environmental Sciences1991，4，3： | 1 |
| 14 | Armored long RNA controls or standards for branched DNA assay for detection of humanimmunodeficiency virus type 1 显示文摘 | Zhan Sien Li Jinming Xu Ruihuan | 2009 | Journal of Clinical Microbiology2009，47，8： | 1 |
| 15 | Ca- talytic activity of Fe/SBA-15 for ozonation of dimethyl phthalate in aqueous solution 显示文摘 | Huang Ruihuan Yan Huihua Li laisheng | 2011 | Appl Catal B2011，106，12： | 1 |
| 16 | Catalytic ozonation of p-chlorobenzoic acid over MCM-41 and Fe loaded MCM-41显示文摘 | Huang Ruihuan Lan Bingyan Chen Zhongying | 2012 | Chemical Engineering Journal2012，180，： | 1 |
| 17 | Armored long RNA controls or standards for branched DNA assay for detection of human immunodeficiency virus type 1显示文摘 | Sien Zhan Jinming Li Ruihuan Xu Lunan Wang Kuo Zhang Rui Zhang | 2009 | J Clin Microbiol2009，47，8： | 1 |
| 18 | Armored long RNA controls or standards for branched DNAassayfor detection of human immunodeficiency virus Type l显示文摘 | Zhan Sien LiJinming Xu Ruihuan | 2009 | J ClinMicrobiol2009，47，8： | 1 |
| 19 | On the determination of particle impact breakage in selection function显示文摘This paper presents a thorough study of particle impact breakage in selection function with a unified breakage criterion.The impact mode and breakage pattern for particulate materials are classified based on a significant review of well-established impact testers.It was found that the lack of a unified breakage criterion to determine the breakage probability disables a direct comparison of particle breakage propensity from different impact loading testers.The literature breakage models to describe the breakage probability are reviewed where the advantage and drawback of these models are scrutinized.The sourced literature breakage models are compared with the zeolite breakage datasets in a unified breakage criterion to evaluate the model performance.A novel computational modelling workflow for a milling process is proposed to provide a guidance in implementing the digital twin in milling process prediction.The breakage probability models,i.e.the selection functions are comprehensively assessed in population balance model to examine the model serviceability.The model simplicity and fidelity in the model assessment are specifically discussed and the value of digital twin in substantially reducing the experimental trials is highlighted. | Li Ge Wang Ruihuan Ge Xizhong Chen | 2022 | Particuology2022，20，6： | 1 |
| 20 | Construction of Armored RNA Containing Long-Size Chimeric RNA by Increasing the Number and Affinity of the Pac Site in Exogenous RNA and Sequence Coding Coat Protein of the MS2 Bacteriophage显示文摘 | Wei Baojun Wei Yuxiang Zhang Kuo Yang Changmei Wang Jing Xu Ruihuan Zhan Sien Lin Guigao Wang Wei Liu Min Wang Lunan Zhang Rui Li Jinming | 2008 | Intervirology2008，，2： | 1 |
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