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| 1 | Regulation of the inflammatory cycle by a controllable release hydrogel for eliminating postoperative inflammation after discectomy显示文摘Surgery is the final choice for most patients with intervertebral disc degeneration(IDD).Operation-caused trauma will cause inflammation in the intervertebral disc.Serious inflammation will cause tissue defects and induce tissue degeneration,IDD recurrence and the occurrence of other diseases.Therefore,we proposed a scheme to treat recurrence after discectomy by inhibiting inflammation with an aspirin(ASP)-loaded hydrogel to restore the mechanical stability of the spine and relieve local inflammation.ASP-liposomes(ASP-Lips)were incorporated into a photocrosslinkable gelatin-methacryloyl(GelMA)via mixing.This material can effectively alleviate inflammation by inhibiting the release of high mobility group box 1(HMGB1)from the nucleus to the cytoplasm.We further assessed the expression of inflammatory cytokines,such as interleukin 6(IL-6)and tumor necrosis factor-α(TNF-α),and degeneration-related factors,such as type II collagen(COL-2),Aggrecan,matrix metallopeptidases-3(MMP-3),MMP-13,a disintegrin and metalloproteinase with thrombospondin motifs-4(ADAMTS-4)and ADAMTS-5 in rat nucleus pulpous cells.The level of IDD was analyzed through H&E,safranin-O staining and immunohistochemistry in rabbit samples.In vitro,we found that ASP-Lip@GelMA treatment significantly decreased inflammatory cytokines,MMP-3 and-13,and ADAMTS-4 and-5 and up-regulated COL-2 and Aggrecan via the inhibited release of HMGB-1 from the nucleus.In vivo,ASP-Lip@GelMA can effectively inhibit inflammation of local tissue after disc surgery and fill local tissue defects.This composite hydrogel system is a promising way to treat the recurrence of IDD after surgery without persistent complications. | Yu Liu Jiacheng Du Peng Peng Ruoyu Cheng Jiayi Lin Congxin Xu Huilin Yang Wenguo Cui Haiqing Mao Yuling Li Dechun Geng | 2021 | Bioactive Materials2021,6,1: | 6 |
| 2 | Fast and uniform growth of graphene glass using confined-flow chemical vapor deposition and its unique applications显示文摘常规玻璃上的高质量的 graphene 的快、一致的生长为 graphene 玻璃的实际应用程序是很重要的。我们此处为 graphene 玻璃的高效率的制造报导一条范围流动化学药品蒸汽免职(CVD ) 途径。我们的途径的特色是 2-4 m 的制造在玻璃底层上面的宽差距,与很多的跌倒块;这差距被发现显著地增加在对方之间并且与玻璃表面的碳先锋和反应碎片的碰撞概率。作为结果, graphene 玻璃的生长率显著地增加了,和在象与那些相比的生长质量和在常规煤气的流动 CVD 技术的一致性的改进。这些高质量的 graphene 眼镜与以前报导的那些相比以许多更高的 defogging 速度和更高的稳定性展出了优秀 defogging 表演。graphene 蓝宝石玻璃被发现是为种制服和极端光滑的铝氮化物的理想的底层没有缓冲区层的乏味的免职前的薄电影。介绍范围流动 CVD 途径为 graphene 玻璃的大量生产提供一条简单、便宜的线路,它被相信支持各种各样的 graphene 眼镜的实际应用。 | Zhaolong Chen Baolu Guan Xu-dong Chen Qing Zeng Li Lin Ruoyu Wang Manish Kr. Priydarshi Jingyu Sun Zhepeng Zhang Tongbo Wei Jinmin LI Yanfeng Zhang Yingying Zhang Zhongfan Liu | 2016 | Nano Research2016,9,10: | 5 |
| 3 | N, F?Codoped Microporous Carbon Nanofibers as Efficient Metal?Free Electrocatalysts for ORR显示文摘Currently, the oxygen reduction reaction(ORR) mainly depends on precious metal platinum(Pt) catalysts. However, Pt-based catalysts have several shortcomings, such as high cost, scarcity, and poor long-term stability. Therefore, development of e cient metal-free electrocatalysts to replace Pt-based electrocatalysts is important. In this study, we successfully prepared nitrogen-and fluorinecodoped microporous carbon nanofibers(N, F-MCFs) via electrospinning polyacrylonitrile/polyvinylidene fluoride/polyvinylpyrrolidone(PAN/PVDF/PVP) tricomponent polymers followed by a hydrothermal process and thermal treatment, which was achieved for the first time in the literature. The results indicated that N, F-MCFs exhibit a high catalytic activity(E_(onset): 0.94 V vs. RHE, E_(1/2): 0.81 V vs. RHE, and electron transfer number: 4.0) and considerably better stability and methanol tolerance for ORR in alkaline solutions as compared to commercial Pt/carbon(Pt/C, 20 wt%) catalysts. Furthermore, in acidic media, N, F-MCFs showed a four-electron transfer pathway for ORR. This study provides a new strategy for in situ synthesis of N, F-MCFs as highly e cient metal-free electrocatalysts for ORR in fuel cells. | Tianle Gong Ruoyu Qi Xundao Liu Hong Li Yongming Zhang | 2019 | Nano-Micro Letters2019,11,1: | 3 |
| 4 | Conjugated polyelectrolytes for label-free visual detection of heparin显示文摘Conjugated polyelectrolytes (CPEs),with electron-delocalized backbones and charged ionic side chains,are unique sensory materials for the construction of optical biosensors.In this feature article,CPE-based visual detection of heparin is summarized.Three CPE-based heparin probes,including ratiometric,light-up and colormetric probes,are discussed in terms of molecular design,detection selectivity and quantification capability.The work summarized here provides fundamental guidelines for CPE-based label-free visual sensing. | PU KanYi ZHAN RuoYu LIANG Jing LIU Bin | 2011 | Science China Chemistry2011,54,4: | 3 |
| 5 | Preparation and characterization of carbonyl iron/strontium hexaferrite magnetorheological fluids显示文摘The heat transfer oil-based magnetorheological fluid(MRF) was prepared using oleic acid-modified micron carbonyl iron powder as a magnetic dispersed phase and strontium hexaferrite(SrFe_(12)O_(19))nanoparticles as an additive.The sedimentation stability of MRFs was studied.The results indicated that the stability of MRFs was improved remarkably by adding SrFe_(12)O_(19) nanoparticles and the sedimentation ratio was only 0.88 in 20 days when the content of nanoparticles reached 10 wt%.The Theological properties were characterized by a HAAKE rheometer without a magnetic field and a capillary rheometer with and without a magnetic field.The effects of SrFe_(12)O_(19) nanoparticles,the temperature,and magnetic field strength were investigated.In addition,the rheological properties could be predicted well using the improved Herschel-Bulkley model,even under a magnetic field.A theoretical model was also proposed to predict the yield stress based on the microstructure of the MRF under an applied magnetic field. | Jianrong Liu Xianjun Wang Xia Tang Ruoyu Hong Yaqiong Wang Wenguo Feng | 2015 | Particuology2015,13,5: | 3 |
| 6 | Influence of proximity to the Qinghai-Tibet highway and railway on variations of soil heavy metal concentrations and bacterial community diversity on the Tibetan Plateau显示文摘An understanding of soil microbial communities is crucial in roadside soil environmental assessments.The 16S rRNA se quencing of a stressed microbial community in soil adjacent to the Qinghai-Tibet Highway(QTH)revealed that the accu mulation of heavy metals(over about 10 years)has affected the diversity of bacterial abundance and microbial community structure.The proximity of a sampling site to the QTH/Qinghai-Tibet Railway(QTR),which is effectively a measure of the density of human engineering,was the dominant factor influencing bacterial community diversity.The diversity of bacterial communities shows that 16S rRNA gene abundance decreased in relation to proximity to the QTH and QTR in both alpine wetland and meadow areas.The dominant phyla across all samples were Actinobacteria and Proteobacteria.The concentration of Cr and Cd in the soil were positively correlated with proximity to the QTH and QTR(MC/WC sam pling sites),and Ni,Co,and V were positively correlated with proximity to the QTH and QTR(MA/WA sampling sites).The results presented in this study provide an insight into the relationships among heavy metals and soil microbial commu nities,and have important implications for assessing and predicting the impacts of human-induced activities from the QTH and QTR in such an extreme and fragile environment. | Xia Zhao JunFeng Wang Yun Wang Xiang Lu ShaoFang Liu YuBao Zhang ZhiHong Guo ZhongKui Xie RuoYu Wang | 2019 | Research in Cold and Arid Regions2019,11,6: | 2 |
| 7 | SiOx/C-Ag nanosheets derived from Zintl phase CaSi_(2) via a facile redox reaction for high performance lithium storage显示文摘As one of the high-capacity anodes in lithium-ion batteries(LIBs),silicon oxide(SiOx)has attracted wide attention due to its high theoretical capacity,low cost,and proper working voltage.However,the huge volume change and the intrinsic poor conductivity of SiOx still hinder the practical applications.How to address the issues is the focus of current research.In this work,firstly,hydrogen passivated Si nanosheets(Si6H6)were prepared from Zintl phase CaSi2,then,two-dimensional Ag nanoparticle modified SiOVC nanocomposite was prepared via a facile complex redox reaction between SieH6 and AgN03-aniline complexing agent.In this design,aniline was served as carbon sources,and Si6H6could be transformed to SiOx by AgN03 in mild solution condition.The obtained Ag modified SiOVC(SiOx/C-Ag)electrode exhibited high specific capacity(550 mAh·g^(-1)at 0.6 A·g^(-1)),superior rate,and cycling performance when served as anode for LIBs. | Jie Xie Lin Sun Yanxiu Liu Xinguo Xi Ruoyu Chen Zhong Jin | 2022 | Nano Research2022,15,1: | 2 |
| 8 | Prediction of curved oil–water interface in horizontal pipes using modified model with dynamic contact angle显示文摘In this study,interface shapes of horizontal oil–water two-phase flow are predicted by using Young-Laplace equation model and minimum energy model.Meanwhile,the interface shapes of horizontal oil–water twophase flow in a 20 mm inner diameter pipe are measured by a novel conductance parallel-wire array probe(CPAP).It is found that,for flow conditions with low water holdup,there is a large deviation between the model-predicted interface shape and the experimentally measured one.Since the variation of pipe wetting characteristics in the process of fluid flow can lead to the changes of the contact angle between the fluid and the pipe wall,the models mentioned above are modified by considering dynamic contact angle.The results indicate that the interface shapes predicted by the modified models present a good consistence with the ones measured by CPAP. | Hongxin Zhang Lusheng Zhai Ruoyu Liu Cong Yan Ningde Jin | 2020 | Chinese Journal of Chemical Engineering2020,28,3: | 2 |
| 9 | Identification of prognostic biomarkers in hepatitis B virus-related hepatocellular carcinoma and stratification by integrative multi-omics analysis显示文摘 | Ruoyu Miao Haitao Luo Huandi Zhou Guangbing Li Dechao Bu Xiaobo Yang Xue Zhao Haohai Zhang Song Liu Ying Zhong Zhen Zou Yan Zhao Kuntao Yu Lian He Xinting Sang Shouxian Zhong Jiefu Huang Yan Wu Rebecca A. Miksad Simon C. Robson Chengyu Jiang Yi Zhao Haita | 2014 | Journal of Hepatology2014,,: | 2 |
| 10 | MEASUREMENT AND INFLUENCE FACTOR'S ANALYSING OF INTERFACIAL STRENGTH OF COMPOSITES显示文摘MEASUREMENTANDINFLUENCEFACTOR'SANALYSINGOFINTERFACIALSTRENGTHOFCOMPOSITES¥WangLingsen;LiuRuoyu;ZangJinsen;FanYi(ResearchInsti... | Wang Lingsen Liu Ruoyu Zang Jinsen Fan Yi (Research Institute of Powder Metallurgy, Central South University of Technology, Changsha 410083) | 1996 | 中国有色金属学会会刊:英文版1996,6,3: | 1 |
| 11 | Investigation on Structural and Thermodynamic Characteristics of Perhydrous Bituminous Coal by Fourier Transform Infrared Spectroscopy and Thermogravimetry/mass Spectrometry显示文摘 | Wu Dun Liu Guijian Sun Ruoyu | 2014 | Energy and Fuels2014,28,5: | 1 |
| 12 | Prevalent fecal contamination in drinking water resources and potential health risks in Swat, Pakistan显示文摘Fecal bacteria contaminate water resources and result in associated waterborne diseases.This study assessed drinking water quality and evaluated their potential health risks in Swat, Pakistan. Ground and surface drinking water were randomly collected from upstream to downstream in the River Swat watershed and analyzed for fecal contamination using fecal indicator bacteria(Escherichia coli) and physiochemical parameters(potential of hydrogen, turbidity, temperature, electrical conductivity, total dissolved solid, color, odor and taste). The physiochemical parameters were within their safe limits except in a few locations, whereas, the fecal contaminations in drinking water resources exceeded the drinking water quality standards of Pakistan Environmental Protection Agency(Pak-EPA),2008 and World Health Organization(WHO), 2011. Multivariate and univariate analyses revealed that downstream urbanization trend, minimum distance between water sources and pit latrines/sewerage systems, raw sewage deep well injection and amplified urban,pastures and agricultural runoffs having human and animal excreta were the possible sources of contamination. The questionnaire survey revealed that majority of the local people using 10–20 years old drinking water supply schemes at the rate of 73% well supply,13% hand pump supply, 11% spring supply and 3% river/streams supply, which spreads high prevalence of water borne diseases including hepatitis, intestinal infections and diarrhea, dysentery, cholera, typhoid fever, jaundice and skin diseases in children followed by older and younger adults. | Kifayatullah Khan Yonglong Lu Mian Abdal Saeed Hazrat Bilal Hassan Sher Hizbullah Khan Jafar Ali Pei Wang Herman Uwizeyimana Yvette Baninla Qifeng Li Zhaoyang Liu Javed Nawab Yunqiao Zhou Chao Su Ruoyu Liang | 2018 | Journal of Environmental Sciences2018,30,10: | 1 |
| 13 | pUGTdb:A comprehensive database of plant UDP-dependent glycosyltransferases显示文摘Dear Editor,Plant UDP-dependent glycosyltransferases(UGTs),belonging to the carbohydrate-active enzyme glycosyltransferase 1 family(Louveau and Osbourn,2019),not only play important roles in adaptation to various environments(Cai et al.,2020;Pastorczyk-Szlenkier and Bednarek,2021)but also endow plant natural products with great pharmaceutical and ecological significance(Margolin et al.,2020).In recent years,an increasing number of plant UGTs have been characterized to function in the biosynthesis of many bioactive compounds such as ginsenosides(Wei et al.,2015),breviscapine(Liu et al.,2018),and rubusoside(Xu et al.,2022). | Yuqian Liu Qian Wang Xiaonan Liu Jian Chengi Lei Zhang Huanyu Chu Ruoyu Wang Haoran Li Hong Chang Nida Ahmed Zhonghua Wang Xiaoping Liao Huifeng Jiang | 2023 | Molecular Plant2023,16,4: | 1 |
| 14 | An overview of the switching parameter variation of RRAM显示文摘Resistive random access memory(RRAM) has been considered as one of the most promising candidates for next-generation nonvolatile memory, due to its advantages of simple device structure, excellent scalability, fast operation speed and low power consumption. Deeply understanding the physical mechanism and effectively controlling the statistical variation of switching parameters are the basis of fostering RRAM into commercial application. In this paper, based on the deep understanding on the mechanism of the formation and rupture of conductive filament, we summarize the methods of analyzing and modeling the statistics of switching parameters such as SET/RESET voltage, current, speed or time. Then, we analyze the distributions of switching parameters and the influencing factors. Additionally, we also sum up the analytical model of resistive switching statistics composed of the cell-based percolation model and SET/RESET switching dynamics. The results of the model can successfully explain the experimental distributions of switching parameters of the Ni O- and Hf O2-based RRAM devices. The model also provides theoretical guide on how to improve the uniformity and reliability such as disturb immunity. Finally, some experimental approaches to improve the uniformity of switching parameters are discussed. | Meiyun Zhang Shibing Long Guoming Wang Yang Li Xiaoxin Xu Hongtao Liu Ruoyu Liu Ming Wang Congfei Li Pengxiao Sun Haitao Sun Qi Liu Hangbing L Ming Liu | 2014 | Chinese Science Bulletin2014,59,36: | 1 |
| 15 | Conjugated polyelectrolyte as signal amplifier for fluorogenic probe based enzyme activity study显示文摘 | Zhan Ruoyu Tan Angela Jun Hiong Liu Bin | | 0,,02: | 1 |
| 16 | The research of image detailenhancement algorithm with Laplacian pyramid 显示文摘 | Teng Yan wen Liu Fuyan Wu Ruoyu | 2013 | Green Compu-ting and Communicatims2013,32,10: | 1 |
| 17 | Controlled adsorption of cellulase onto pretreated corncob by pH adjustment显示文摘 | Ruoyu Du Rongxin Su Xuan Li Xiaowei Tantai Zhaohui Liu Jifeng Yang Wei Qi Zhimin He | 2012 | Cellulose2012,,2: | 1 |
| 18 | RNA m^(6)A modification orchestrates a LINE-1-host interaction that facilitates retrotransposition and contributes to long gene vulnerability显示文摘The molecular basis underlying the interaction between retrotransposable elements(RTEs)and the human genome remains poorly understood.Here,we profiled N^(6)-methyladenosine(m^(6)A)deposition on nascent RNAs in human cells by developing a new method MINT-Seq,which revealed that many classes of RTE RNAs,particularly intronic LINE-1s(Lis),are strongly methylated. | Feng Xiong Ruoyu Wang Joo-Hyung Lee Shenglan Li Shin-Fu Chen Zian Liao Lana AI Hasani Phuoc T.Nguyen Xiaoyu Zhu Joanna Krakowiak Dung-Fang Lee Leng Han Kuang-Lei Tsai Ying Liu Wenbo Li | 2021 | Cell Research2021,31,8: | 1 |
| 19 | In vitro interaetiorns of micafungin with amphotericin B,itraconazole or fluconazole against the pathogenic Phase of penicillium marneffei显示文摘 | Cunwei Cao Wei Liu Ruoyu Li | 2009 | Journal of Antimicrobial chemotherapy2009,63,: | 1 |
| 20 | Preparation of Fe 3 O 4 –chitosan nanoparticles used for hyperthermia显示文摘 | Jingmiao Qu Guang Liu Yiming Wang Ruoyu Hong | 2010 | Advanced Powder Technology2010,,4: | 1 |