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| 1 | Diagnostic dilemma of abdominal tuberculosis in non-HIV patients:An ongoing challenge for physicians显示文摘AIM: To assess the clinical features, yield of the diagnostic tests and outcome of abdominal tuberculosis in non-HIV patients. METHODS: Adult patients with discharge diagnosis of abdominal tuberculosis (based upon; positive microbiology, histo-pathology, imaging or response to trial of anti TB drugs) during the period 1999 to 2004 were analyzed. Patient’s characteristics, laboratory investigations, radiological, endoscopic and surgical findings were evaluated. Abdominal site involved (intestinal, peritoneal, visceral, and nodal) and response to treatment was also noted. RESULTS: There were 209 patients enrolled. One hundred and twenty-three (59%) were females. Symptoms were abdominal pain 194 (93%), fever 134 (64%), night sweats 99 (48%), weight loss 98 (47%), vomiting 75 (36%), ascites 74 (35%), constipation 64 (31%), and diarrhea 25 (12%). Sub-acute and acute intestinal obstruction was seen in 28 (13%) and 12 (11%) respectively. Radiological evidence of pulmonary tuberculosis was found in 134 (64%) patients. Basis of diagnosis of abdominal tuberculosis were radiology (Chest and barium X-Rays, Ultrasound and CT scan abdomen) in 111 (53%) and histo-pathology (tissue obtained during surgery, colonoscopy, CT or ultrasound guided biopsy, laparoscopy and upper gastro intestinal endoscopy) in 87 (42%) patients. Mycobacterium culture was positive in 6/87 (7%) patients and response to therapeutic trial of anti tubercular drugs was the basis of diagnosis in 5 (2.3%) patients. Predominant site of involvement by abdominal TB was intestinal in 103 (49%) patients, peritoneal in 87 (42%) patients, solid viscera in 10 (5%) and nodal in 9 (4%) patients. Response to medical treatment was found in 158 (76%) patients andadditionally 35 (17%) patients also underwent surgery. In a 425 ± 120 d follow-up period 12 patients died (eight post operative) and no case of relapse was noted. CONCLUSION: Abdominal TB has diverse and non- specific symptomatology. No single test is adequate for diagnosis of abdominal tuberculosis in all patients. Abdominal TB in non-HIV patients remains an ongoing diagnostic dilemma requiring a high index of clinical suspicion. | Rustam Khan Shahab Abid Wasim Jafri Zaigham Abbas Khalid Hameed Zubair Ahmad | 2006 | World Journal of Gastroenterology2006，12，39： | 17 |
| 2 | 中亚黄土沉积与西风区末次冰期快速气候变化显示文摘气候快速变化过程与机制一直是古气候研究的热点科学问题,随着不同地区高分辨率地质记录的增多,年代学方法的改进,此类快速气候变化事件的区域差异性日益突出,对比和认识这些区域之间的变化细节,有助于认识快速气候变化的规律和驱动机制。文章以中亚黄土为主要研究对象,根据黄土沉积特征与现代气候特征,将中亚黄土分为西部、北部和东部3个亚区,在总结中亚西风区黄土古气候研究进展的基础上,回顾了近年来中亚地区末次冰期西风区气候突变事件研究现状与问题,初步探讨了在亚轨道尺度上末次冰期快速气候变化发生过程和机制。结果表明,粒度、矿物学、地球化学等指标均指示中亚这3个黄土亚区末次冰期确实存在千年尺度的快速气候波动信号,但在年代和变率上存在区域差异,这种差异除了缺乏精确的年代学控制外,还与区域水热组合和区域地形结构有关。这些冷暖的快速气候变化与北大西洋高纬地区冰盖收缩扩张、西伯利亚高压强度和范围的变化导致风动力变化和西风带南北迁移有关。今后需进一步加强高分辨率年代序列的建立,进一步遴选中亚黄土中有效的、能够独立反映风力强度、源区信息、古温度、古降水等代用指标,并结合古气候模拟试验研究其驱动机制。 | 宋友桂 宗秀兰 李越 Rustam Orozbaev Yuns Mamadjanov Jamshed Aminov | 2019 | 第四纪研究2019，39，3： | 14 |
| 3 | 天山北麓地区博乐黄土磁化率、粒度特征与古气候意义显示文摘受西风控制的天山地区黄土广泛分布,是中亚重要的黄土分布区之一。这些陆相风成沉积物为研究中亚干旱区气候环境变化历史提供了重要的信息载体。本文选取天山北麓博乐地区一个厚为12.7 m的黄土剖面作为研究对象,分析了其磁化率、粒度指标的变化特征,并探讨了其古气候意义。结果表明:(1)博乐黄土粒度组成以粉砂为主,是典型的风成沉积物,成壤作用很弱;(2)博乐黄土磁化率变化主要受控于风力强度;(3)剖面粒度的环境敏感粒级为<31.7μm、31.7—282.5μm,分别可能代表风暴过后的浮尘堆积和风暴过程中风力近距离搬运的沉积物组分;(4)博乐黄土MIS(海洋氧同位素)3阶段记录了多次千年尺度气候事件,能与北大西洋Heinrich事件和D-O事件对应,表明中纬度西风环流在传递北大西洋信号到东亚的过程中扮演着重要角色。 | 孙焕宇 宋友桂 李越 陈秀玲 OROZBAEV Rustam | 2018 | 地球环境学报2018，9，2： | 8 |
| 4 | Predictive factors for early aspiration in liver abscess显示文摘AIM: To determine the predictive factors for early aspiration in liver abscess. METHODS: A retrospective analysis of all patients with liver abscess from 1995 to 2004 was performed. Abscess was diagnosed as amebic in 661 (68%) patients, pyogenic in 200 (21%), indeterminate in 73 (8%) and mixed in 32 (3%). Multiple logistic regression analysis was performed to determine predictive factors for aspiration of liver abscess. RESULTS: A total of 966 patients, 738 (76%) male, mean age 43 ± 17 years, were evaluated: 540 patients responded to medical therapy while adjunctive percutaneous aspiration was performed in 426 patients. Predictive factors for aspiration of liver abscess were: age ≥ 55 years, size of abscess ≥ 5 cm, involvement of both lobes of the liver and duration of symptoms ≥ 7 d. Hospital stay in the aspiration group was relatively longer than in the non aspiration group. Twelve patients died in the aspiration group and this mortality was not statistically significant when compared to the non aspiration group. CONCLUSION: Patients with advanced age, abscess size > 5 cm, both lobes of the liver involvement and duration of symptoms > 7 d were likely to undergo aspiration of the liver abscess, regardless of etiology. | Rustam Khan Saeed Hamid Shahab Abid Wasim Jafri Zaigham Abbas Mohammed Islam Hasnain Shan Shaalan Beg | 2008 | World Journal of Gastroenterology2008，14，13： | 8 |
| 5 | Hepatic steatosis and fibrosis: Non-invasive assessment显示文摘Chronic liver disease is a major cause of morbidity and mortality worldwide and usually develops over many years, as a result of chronic inflammation and scarring, resulting in end-stage liver disease and its complications. The progression of disease is characterised by ongoing inflammation and consequent fibrosis, although hepatic steatosis is increasingly being recognised as an important pathological feature of disease, rather than being simply an innocent bystander. However, the current gold standard method of quantifying and staging liver disease, histological analysis by liver biopsy, has several limitations and can have associated morbidity and even mortality. Therefore, there is a clear need for safe and noninvasive assessment modalities to determine hepatic steatosis, inflammation and fibrosis. This review covers key mechanisms and the importance of fibrosis and steatosis in the progression of liver disease. We address non-invasive imaging and blood biomarker assessments that can be used as an alternative to information gained on liver biopsy. | Rustam N Karanjia Mary ME Crossey I Jane Cox Haddy KS Fye Ramou Njie Robert D Goldin Simon D Taylor-Robinson | 2016 | World Journal of Gastroenterology2016，22，45： | 6 |
| 6 | Effect of water deficiency on relationships between metabolism,physiology,biomass,and yield of upland cotton(Gossypium hirsutum L.)显示文摘Drought is a common abiotic stress that considerably limits crop production. The objective of this study is to explore the influence of water deficiency on the yield, physiologic and metabolomic attributes in upland cotton cultivars(Gossypium hirsutum L). Cotton cultivars, 'Ishonch' and 'Tashkent-6' were selected to study the relationships among their physiologic, metabolomic and yield attributes during water deficiency. Deficit irrigation was designed by modifying the traditional watering protocol to reduce water use. Results indicate that cotton cultivars respond differently to water deficit stress. Water deficit significantly influenced plant height, the number of internodes, and sympodial branches in both cultivars. However, yield components such as the number of bolls, boll seed, lint mass, and individual plant yield were significantly reduced only in 'Tashkent-6'. The leaf area decreased and the specific leaf weight increased in 'Ishonch' under deficit irrigation conditions. However, 'Tashkent-6' demonstrated significant water loss compared to 'Ishonch', and both cultivars showed reduced transpiration rates. Untargeted metabolite profiles of leaves showed clear separation in 'Ishonch', but not in 'Tashkent-6' under deficit irrigation compared to full irrigation. The individual metabolites such as proline and galactinol showed strong association with yield under water deficit stress. Moreover, this study indicates that leaf area and transpiration intensity influence yield during water deficiency. In summary, the correlation among morpho-physiologic, metabolic, and yield components significantly varied between the two cultivars under water deficiency. The flowering stage was sensitive to water stress for both cultivars. The direct relationship between physiology, metabolism, and yield may be a useful selection criterion for determining candidate parents for cotton drought tolerance breeding. | Tohir A BOZOROV Rustam M USMANOV YANG Honglan Shukhrat A HAMDULLAEV Sardorbek MUSAYEV Jaloliddin SHAVKIEV Saidgani NABIEV ZHANG Daoyuan Alisher A ABDULLAEV | 2018 | Journal of Arid Land2018，10，3： | 5 |
| 7 | 脑海绵状血管畸形临床诊疗指南概要:血管瘤联盟科学咨询委员会临床专家组基于系统文献评价的共识推荐显示文摘背景尽管脑海绵状血管畸形(cerebral cavernous malformation, CCM)的相关研究文献已相当丰富,但在诊断和治疗策略方面仍存在着争议。目的制订CCM诊疗指南。方法作为代表CCM患者和研究的患者支持团体,血管瘤联盟(www.angioma.org)召集了一个包括CCM临床专家在内的多学科写作组来帮助总结现有的CCM临床诊疗相关文献,重点关注5个主题:(1)流行病学和自然病程;(2)遗传检测和咨询;(3)诊断标准和影像学标准;(4)神经外科注意事项;(5)神经内科注意事项。写作组根据预定方案进行了文献回顾和证据评价,最终制定推荐意见,并且确立了共识、争议和知识空白。结果根据方法学标准从1983年1月1日至2014年9月31日期间公开发表的1 270篇文献中筛选出98篇,并确定了另外38篇近期或相关的文献。各主题作者利用这些文献总结了现有知识并形成了23项共识诊疗推荐,同时根据美国心脏协会/美国卒中协会标准进行了推荐强度(效应量)和证据水平(确定性估计)评级。其中,尚无A级证据(因为缺乏随机对照试验),B级证据11项(48%),C级证据12项(52%);Ⅰ级推荐8项(35%),Ⅱ级推荐10项(43%),Ⅲ级推荐5项(22%)。结论现有证据支持对CCM诊疗的推荐,但这些证据的级别和推荐强度普遍较低,因此需要进一步研究来帮助进行更好的临床实践并更新这些推荐。完整的推荐文档包括引用文献的纳入标准、关于各项推荐更详尽的评判标准以及各种争议和知识空白的总结,同样通过了同行评议并可在线获取(www.angioma.org/CCMGuidelines)。 | Amy Akers Rustam Al-Shahi Salman Issam A. Awad Kristen Dahlem Kelly Flemming Blaine Hart Helen Kim Ignacio Jusue-Torres Douglas Kondziolka Cornelia Lee Leslie Morrison Daniele Rigamonti Tania Rebeiz Elisabeth Toumier-Lasserve Darrel Waggoner Kevin Whitehead 鄂同舟 雷宇 倪伟 顾宇翔 | 2017 | 国际脑血管病杂志2017，25，7： | 4 |
| 8 | Fate and Transport of Antibiotic Residues and Antibiotic Resistance Genes following Land Application of Manure Waste显示文摘 | Chee-Sanford Joanne C Mackie Roderick I Koike Satoshi Krapac Ivan G Lin Yu-Feng Yannarell Anthony C Maxwell Scott Aminov Rustam I | 2009 | Journal of Environmental Quality2009，，3： | 3 |
| 9 | Regolith thickness modeling using a GIS approach for landslide distribution analysis, NW Himalayas显示文摘Regolith thickness is considered as a contributing factor for the occurrence of landslides.Although, mostly it is ignored because of complex nature and as it requires more time and resources for investigation. This study aimed to appraise the role of regolith thickness on landslide distribution in the Muzaffarabad and surrounding areas, NW Himalayas.For this purpose regolith thickness samples were evenly collected from all the lithological units at representative sites within different slope and elevation classes in the field. Topographic attributes(slope, aspect, drainage, Topographic Wetness Index,elevation and curvature) were derived from the Digital Elevation Model(DEM)(12.5 m resolution).Arc GIS Model Builder was used to develop the regolith thickness model. Stepwise regression technique was used to explore the spatial variation of regolith thickness using topographic attributes and lithological units. The derived model explains about 88% regolith thickness variation. The model was validated and shows good agreement(70%) between observed and predicted values. Subsequently, the derived regolith model was used to understand the relationship between regolith thickness and landslide distribution. The analysis shows that most of the landslides were located within 1-5 m regolith thickness. However, landslide concentration is highest within 5-10 m regolith thickness, which shows that regolith thickness played a significant role for the occurrence of landslide in the studied area. | Muhammad BASHARAT Masood QASIM Muhammad SHAFIQUE Nasir HAMEED Muhammad Tayyib RIAZ Muhammad Rustam KHAN | 2018 | Journal of Mountain Science2018，15，11： | 2 |
| 10 | 光伏发电储能系统接入电气化铁路的探讨显示文摘为了实现铁路领域的节能减排和可持续发展,提出一种基于背靠背变流器将储能与光伏系统接入铁路牵引供电系统的方案。分析了系统工作原理,提出了一种上层能量管理、下层变流器控制的协调控制策略,并仿真验证了该供电方案与控制策略的正确性和有效性。 | Khamdamov Rustam 朱远帆 周应东 | 2019 | 电工技术2019，，7： | 2 |
| 11 | Al-Cu-Mg-Ag合金T6和T840条件下的高周疲劳性能(英文)显示文摘研究Al-Cu-Mg-Ag合金系AA2139合金在T6和T840条件下的高周疲劳行为。T840处理是在峰时效前进行压下量为40%的冷轧。与T6态相比,T840可提高合金的拉伸强度。但是两种条件下的疲劳寿命基本相同,因为热力加工过程对裂纹的萌生和扩展的影响较小。 | Marat GAZIZOV Rustam KAIBYSHEV | 2017 | Transactions of Nonferrous Metals Society of China2017，27，6： | 2 |
| 12 | Feature based passive acoustic detection of underwater threats显示文摘 | Rustam S Alexander S Sreeram R | 2006 | Proceedings of SPIE2006，6204，620408： | 1 |
| 13 | Aeolian dust dynamics in the Fergana Valley, Central Asia, since -30 ka inferred from loess deposits显示文摘Knowledge of the interactions among atmospheric dynamics,dust emissions and climate system is essential to understand the physical mechanisms for the dust lifecycle,their role in loess formation as well as the predictions of future dust concentration.However,these issues still remain relatively poorly known in Central Asia(CA).The extensive loess deposits on the CA pediments provide a promising archive to explore atmospheric dust dynamics and climatic conditions in the past and their association with loess formation.This study investigates the granulometric and magnetic properties of a loess section(named Osh section)in the Fergana Valley,which provides a sensitive record of atmospheric dust dynamics since 30 ka based on radiometric(AMS ^(14)C)dating.The frequency-dependent magnetic susceptibility(χfd)and the mean grain size are used to reconstruct the broadscale effective moisture and summer atmospheric dynamics pattern in CA,respectively.The results show that the precession forcing exerts a huge influence on the wind-regime variabilities in CA,but with different physical processes under the impact of the Northern Hemisphere ice sheet(NHIS)before and after 15 ka.The origin of the sedimentation rate variations in the Osh loess is also linked to the NHIS-modulated changes of the atmospheric circulation patterns.Either the strengthened westerlies or the increased surface roughness from higher vegetation cover in loess-deposition areas have significantly accelerated the loess accumulation.As a result,these complicated influence factors of sedimentation rate change in the Osh loess section,especially during the Holocene epoch,may hamper accessibility of the authentic dust emission flux and atmospheric dust concentration in CA. | Yue Li Yougui Song Dimitris G.Kaskaoutis Jinbo Zan Rustam Orozbaev Liangcheng Tan Xiuling Chen | 2021 | Geoscience Frontiers2021，12，5： | 1 |
| 14 | Atomic layer deposited (ALD) TiO2 on fibrous nano-silica (KCC-1) for photocatalysis: nanoparticle formation and size quantization effect显示文摘 | Rustam Singh Qin Lijun Feng Hao | 2016 | ACS Ca- talysis2016，6，5： | 1 |
| 15 | Biomedical research: increasing value, reducing waste显示文摘 | Malcolm R Macleod Susan Michie Ian Roberts Ulrich Dirnagl Iain Chalmers John P A Ioannidis Rustam Al-Shahi Salman An-Wen Chan Paul Glasziou | 2014 | The Lancet . 2014 (9912)2014，，9912： | 1 |
| 16 | Passive acoustic detection of modulated underwater sounds from biological and anthro- pogenic sources显示文摘 | Rustam Stolkin Sreeram Radhakrishnan Alexander Sutin | 2007 | Oceans2007，，1： | 1 |
| 17 | Rumen Bacterial Community Transition During Adaptation to High-grain Diet显示文摘 | Kiyoshi Tajima Shozo Arai Koretsugu Ogata Takafumi Nagamine Hiroki Matsui Mutsumi Nakamura Rustam I. Aminov Yoshimi Benno | 2000 | Anaerobe2000，，5： | 1 |
| 18 | Dynamic and post-dynamic recrystallization under hot, cold and severe plastic deformation conditions显示文摘 | Taku Sakai Andrey Belyakov Rustam Kaibyshev Hiromi Miura John J. Jonas | 2014 | Progress in Materials Science2014，，： | 1 |
| 19 | Using environmental models to op- timize sensor placement显示文摘 | Rustam S Lucas V Jeffrey N | 2007 | IEEE Sensors Journals2007，7，3： | 1 |
| 20 | A system atic review of the frequency and probnosis of arteriove- nousm alformations of the brain in adults 显示文摘 | Rustam A 1-shahi Charles W arlow | 2001 | brain2001，124，10： | 1 |
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