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    题名 作者 年代 出处 被引量
12019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W 2020中华高血压杂志2020,28,3:516
2体内腺相关病毒-常间回文重复序列丛集及其相关蛋白9介导的基因编辑可改善家族性高胆固醇血症的动脉粥样硬化显示文摘低密度脂蛋白受体(low-density lipoprotein receptor,Ldlr)基因突变是家族性高胆固醇血症的主要原因之一,可导致动脉粥样硬化,并具有很高的终生心血管病风险。常间回文重复序列丛集(clustered regularly interspaced short palindromic repeats,CRISPR)/CRISPR相关蛋白9(CRISPR-related protein 9,Cas9)系统是基因编辑纠正基因突变从而改善疾病的有效工具。该研究的目的是通过腺相关病毒(adeno-associated virus,AAV)携带的CRISPR/Cas9系统进行体内体细胞基因编辑,以确定其能否在小鼠模型中治疗由Ldlr突变体引起的家族性高胆固醇血症。刘青(译) 叶鹏(审校) Zhao H Li Y He L Pu W Yu W Li Y Wu YT Xu C Wei Y Ding Q Song BL Huang H Zhou B 2020中华高血压杂志2020,28,3:22
3健康成人动脉粥样硬化斑块易感性和血栓形成的生物标志物变化与极端空气污染水平相关:北京AIRCHD研究显示文摘空气污染与心血管事件恶化的病理生理机制尚不完全清楚。该文探讨环境空气污染是否可以触发易损斑块.通过全身炎症途径促进血栓形成。方法:在北京AIRCHD研究中.2014-2016年间对73名健康成年人[年龄(23.3±5.4)岁]进行了随访。研究者使用线性混合效应模型评估了空气污染物与动脉粥样硬化斑块易损性、血栓形成和炎症相关生物标志物之间的关系,并使用中介效应分析(mediation analyses)探讨涉及的生物学途径。通过受试者工作特征(receiver operating characteristic,ROC)曲线分析评估每种生物标记物预测环境空气污染暴露的能力。刘青 叶鹏 Xu H Wang T Liu S Brook RD Feng B Zhao Q Song X Yi T Chen J Zhang Y Wang Y Zheng L Rajagopalan S Li J Huang W 2019中华高血压杂志2019,27,4:13
4Mutation analysis of autosomal dominant polycystic kidney disease genes in Han Chinese显示文摘Zhang S Mei C Zhang D Dai B Tang B Sun T Zhao H Zhou Y Li L Wu Y Wang W Shen X Song J 2005第二军医大学学报2005,26,8:6
5The effect of talc on cell nucleation in extrusion foam processing of polypropylene with CO2 and isopentane显示文摘Park C B Cheung L K Song S W 1998Cellular Polymers1998,17,4:2
6Failure of spectra polyethylene fiber-reinforced composites under ballistic impact loading显示文摘Lee B L Song J W Ward J E 1994Journal of Composite Materials1994,28,13:1
7Apreliminary design study for the HYPER system显示文摘PARK W S SONG T Y LEE B O 2002Nuclear Engineering and Design2002,219,3:1
8Bmi-1 is a novel, molecular marker of nasopharyngeal carcinoma progression and immortal- izes primary human nasopharyngeal epithelial cells 显示文摘Song L B Zeng M S Liao W T 2006Cancer Res2006,66,12:1
9Melt blowing of ionic liquid-based cellulose solutions显示文摘Song J Lu F Cheng B W 2014Fibers and Polymers2014,15,2:1
10Anglnex synergizes with radiation therapy to inhibit tumor growth by radiosensitizing endothelial cells显示文摘Dings R P Williams B W Song C W 2005Int J Cancer2005,115,2:1
11显示文摘Zhang X B Song H W Yu L X 2006J Lumin2006,118,:1
12A causal model of the impact of skills, synergy, and design sensitivity on new product performance 显示文摘Song M W Souder E Dyer B 1997Journal of Product Innovation Management1997,14,:1
13Penetration failure of spectra polyethylene fiber-reinforced ballistic-grade composites显示文摘Walsh T F Lee B L Song J W 1998Key Engineering Materials1998,,141143:1
14Nucleating Agent In- duced Impact Fracture Behavior Change in PP/POE Blend显示文摘Bai H W Wang Y Song B 2008Polymer Bulletin2008,62,3:1
15Experimental and numer- ical analysis of heat transfer and Flow Characteristics in Airside of a Flat Tube Bank Plain Fin Heat Ex- changer显示文摘Wu X Wang L B Song K W 2009Computational Thermal Sciences2009,1,4:1
16Protective effect of the a- queous extract from the root of Platycodon grandiflorum on chole- stasis-induced hepatic injury in mice 显示文摘Kim T W Lee H K Song I B 2012Pharm Biol2012,50,12:1
17The effects of crystal structure of the precursor MnO2 on electrochemical properties of spinel LiMn2O4显示文摘WEI Q L WANG X Y YANG X K SHU H B JU B W HU B N SONG Y F 2012J Solid State Electrochem2012,16,7:1
18One-dimensional dynamic compressive behavior of EPDM rubber显示文摘Song B Chen W 2003Journal of Engineering Ma- terials and Technology2003,125,3:1
19Position control of a Stewart platform using inverse dynamics control with approximate dynamics显示文摘Lee S H Song J B Choi W C 2003Mechatronics2003,13,6:1
20Untreated asymptomatic hips in patients with osteonecrosis of the femoral head显示文摘MIN B W SONG K S CHO C H 2008Clin Orthop Relat Res2008,466,5:1
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