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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | 体内腺相关病毒-常间回文重复序列丛集及其相关蛋白9介导的基因编辑可改善家族性高胆固醇血症的动脉粥样硬化显示文摘低密度脂蛋白受体(low-density lipoprotein receptor,Ldlr)基因突变是家族性高胆固醇血症的主要原因之一,可导致动脉粥样硬化,并具有很高的终生心血管病风险。常间回文重复序列丛集(clustered regularly interspaced short palindromic repeats,CRISPR)/CRISPR相关蛋白9(CRISPR-related protein 9,Cas9)系统是基因编辑纠正基因突变从而改善疾病的有效工具。该研究的目的是通过腺相关病毒(adeno-associated virus,AAV)携带的CRISPR/Cas9系统进行体内体细胞基因编辑,以确定其能否在小鼠模型中治疗由Ldlr突变体引起的家族性高胆固醇血症。 | 刘青(译) 叶鹏(审校) Zhao H Li Y He L Pu W Yu W Li Y Wu YT Xu C Wei Y Ding Q Song BL Huang H Zhou B | 2020 | 中华高血压杂志2020，28，3： | 22 |
| 3 | 健康成人动脉粥样硬化斑块易感性和血栓形成的生物标志物变化与极端空气污染水平相关:北京AIRCHD研究显示文摘空气污染与心血管事件恶化的病理生理机制尚不完全清楚。该文探讨环境空气污染是否可以触发易损斑块.通过全身炎症途径促进血栓形成。方法:在北京AIRCHD研究中.2014-2016年间对73名健康成年人[年龄(23.3±5.4)岁]进行了随访。研究者使用线性混合效应模型评估了空气污染物与动脉粥样硬化斑块易损性、血栓形成和炎症相关生物标志物之间的关系,并使用中介效应分析(mediation analyses)探讨涉及的生物学途径。通过受试者工作特征(receiver operating characteristic,ROC)曲线分析评估每种生物标记物预测环境空气污染暴露的能力。 | 刘青 叶鹏 Xu H Wang T Liu S Brook RD Feng B Zhao Q Song X Yi T Chen J Zhang Y Wang Y Zheng L Rajagopalan S Li J Huang W | 2019 | 中华高血压杂志2019，27，4： | 13 |
| 4 | Mutation analysis of autosomal dominant polycystic kidney disease genes in Han Chinese显示文摘 | Zhang S Mei C Zhang D Dai B Tang B Sun T Zhao H Zhou Y Li L Wu Y Wang W Shen X Song J | 2005 | 第二军医大学学报2005，26，8： | 6 |
| 5 | Terahertz Semiconductor Quantum Well Devices显示文摘For eventually providing terahertz science with compact and convenient devices,terahertz (1~10THz) quantum-well photodetectors and quantum-cascade lasers are investigated.The design and projected detector performance are presented together with experimental results for several test devices,all working at photon energies below and around optical phonons.Background limited infrared performance (BLIP) operations are observed for all samples (three in total),designed for different wavelengths.BLIP temperatures of 17,13,and 12K are achieved for peak detection frequencies of 9.7THz(31μm),5.4THz(56μm),and 3.2THz(93μm),respectively.A set of THz quantum-cascade lasers with identical device parameters except for doping concentration is studied.The δ-doping density for each period varies from 3.2×1010 to 4.8×1010cm-2.We observe that the lasing threshold current density increases monotonically with doping concentration.Moreover,the measurements for devices with different cavity lengths provide evidence that the free carrier absorption causes the waveguide loss also to increase monotonically.Interestingly the observed maximum lasing temperature is best at a doping density of 3.6×1010cm-2. | Liu H C Luo H Ban D Waichter M Song C Y Wasilewski Z R Buchanan M Aers G C SpringThorpe A J Cao J C Feng S L Williams B S Hu Q | 2006 | Journal of Semiconductors2006，27，4： | 2 |
| 6 | A Multidimensional Trust Formation Model in B-to-C Ecommerce:A Conceptual Framework and Content Analyses of Academia/Practitioner Perspectives 显示文摘 | Kim D J Song Y I Braynov S B Rao H R | 2005 | Decision Support Systems2005，40，2： | 1 |
| 7 | Nutrients removal and recovery by crystallization of magnesium ammonium phosphate from synthetic swine wastewater显示文摘 | SONG Y H YUAN P ZHENG B H | 2007 | Chemosphere2007，69，2： | 1 |
| 8 | Dynamics of soil organic carbon and its fractions after abandonment of cultivated wetlands in northeast China 显示文摘 | Zhang J B Song C H Wang S M | 2007 | Soil and Tillage Research2007，96，： | 1 |
| 9 | Magnetic and magneto-optical properties of Tb-Fe-Co/Ta multilayers 显示文摘 | Ito H Naoe M | 1994 | IEEE Trans Magn1994，30，612： | 1 |
| 10 | A CMOS adaptive antenna-impedance-tuning IC operating in the 850MHz to 2GHz band显示文摘 | Song H Bakkaloglu B Aberle J T | 2009 | IEEE solid-state circuit2009，，： | 1 |
| 11 | A new model of three-dimensional grain growth:theory and computer simulation of topology-dependency of individual grain growth rate显示文摘 | Liu G Q Yu H B Song X Y | 2001 | Materials & Design2001，22，： | 1 |
| 12 | A method for computing acoustic fields based on the principle of wave superposition显示文摘 | Koopmann G H Song L Fahnline J B | 1989 | The Journal of the Acoustic Society of American1989，88，： | 1 |
| 13 | Physical properties of gelidium corneum-gelatin blend films containing grapefruit seed extract or green tea extract and its application in the packaging of pork loins显示文摘 | HONG Y H LIM G O SONG K B | 2009 | Food Science2009，74，1： | 1 |
| 14 | Petrogenesis of the Mid- dle-Devonian Gushan diorite pluton on the northern margin of the North China block and its implications显示文摘 | Zhang S H Zhao Y Song B | 2007 | Geological Magazine2007，144，： | 1 |
| 15 | Theory and Experi- ment of a 94 GHz Gyrotron Traveling Wave Amplifier显示文摘 | Song H H McDermott D B Hirata | 2004 | Phys Plas2004，11，5： | 1 |
| 16 | Analytical investiga tion of electrical breakdown properties in a nitrogen-SF6 mix turegas显示文摘 | Uhm H S Byeon Y S Song K B | 2010 | Physics of Plasmas2010，17，11： | 1 |
| 17 | IQMNMR:Open source software using time-domain NMR data for automated identification and quantification of metabolites in batches显示文摘 | Song X Zhang B L Liu H M | 2011 | BMC Bioinformatics2011，12，： | 1 |
| 18 | Inorganic Nanoparticles for MRI Contrast Agents显示文摘 | Na H B Song I C Hyeon T | 2009 | Adv Mater2009，21，21： | 1 |
| 19 | 2013, Antigenic and genetic characterization of a European avian-like H1N1 swine influenza virus from a boy in China in 2011显示文摘 | Qi x Cui L Jiao Y Pan Y Li X Zu R Huo X Wu B Tang F Song Y Zhou M Wang H Cardona C J Xing Z | 2013 | Archives of Virology2013，158，1： | 1 |
| 20 | Effects of an interven- tion to improve communication about end-of-life care among African Americans with chronic kidney disease显示文摘 | Song M K Donovan H S Piraino B M | 2010 | Applied Nursing Re search2010，23，2： | 1 |
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