|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Twa1/Gid8 is a β-catenin nuclear retention factor in Wnt signaling and colorectal tumorigenesis显示文摘 | Yi Lu Shanshan Xie Wen Zhang Cheng Zhang Cheng Gao Qiang Sun Yuqi Cai Zhangqi Xu Min Xiao Yanjun Xu Xiao Huang Ximei Wu Wei Liu Fudi Wang Yibin Kang Tianhua Zhou | 2017 | Cell Research2017,27,12: | 9 |
| 2 | Determination of rare earth elements in plant protoplasts by MAA显示文摘A preliminary study on the speciation of rare earth elements in plant cells has been carried out by molecular activation analysis (MAA). Mesophyll protoplasts of Brassica napus were isolated by enzymatic digestion. After being washed with isosmotic solution containing EDTA for several times, the protoplasts were purified by gradient centrifugation. Then the concentration of rare earth elements (REEs) in the protoplasts was determined by neutron activation analysis. The result shows that REEs can enter the cells of the plant. | ZHANG Zhiyong WANG Yuqi SUN Jingxin LI Fuliang CHAI Zhifang XU Lei LI Xin CAO Guoyin | 2000 | Chinese Science Bulletin2000,45,16: | 8 |
| 3 | Regulation of phenylpropanoid biosynthesis by MdMYB88 and MdMYB124 contributes to pathogen and drought resistance in apple显示文摘MdMYB88 and MdMYB124 have been demonstrated to be responsible for lignin accumulation in apple under drought stress.In this study,using a metabolomic approach,we identified differentially accumulated phenylpropanoid and flavonoid metabolites in MdMYB88/124 transgenic RNAi plants under control and long-term drought stress conditions in apple roots.We confirmed the regulation of phenylalanine by MdMYB88 and MdMYB124 via UPLC-MS in apple roots under both control and drought conditions.Using Electrophoretic Mobility Shift Assay(EMSA)and ChIPquantitative PCR(qPCR)analyses,we found that MdMYB88 positively regulates the MdCM2 gene,which is responsible for phenylalanine biosynthesis,through binding to its promoter region.Under long-term drought conditions,MdMYB88/124 RNAi plants consistently accumulated increased amounts of H2O2 and MDA,while MdMYB88 and MdMYB124 overexpression plants accumulated decreased amounts of H2O2 and MDA.We also examined the accumulation of metabolites in the phenylpropanoid biosynthesis pathway in the leaves of MdMYB88 and MdMYB124 transgenic apple plants after long-term drought stress.We found that metabolites responsible for plant defense,including phenylpropanoids and flavonoids,accumulated less in the RNAi plants but more in the overexpression plants under both control and drought conditions.We further demonstrated that MdMYB88/124 RNAi plants were more sensitive to Alternaria alternata f.sp.mali and Valsa mali,two pathogens that currently severely threaten apple production.In contrast,MdMYB88 and MdMYB124 overexpression plants were more tolerant to these pathogens.The cumulative results of this study provided evidence for secondary metabolite regulation by MdMYB88 and MdMYB124,further explained the molecular roles of MdMYB88 and MdMYB124 in drought resistance,and provided information concerning molecular aspects of their roles in disease resistance. | Dali Geng Xiaoxia Shen Yinpeng Xie Yusen Yang Ruiling Bian Yuqi Gao Pengmin Li Liying Sun Hao Feng Fengwang Ma Qingmei Guan | 2020 | Horticulture Research2020,7,1: | 5 |
| 4 | Cenozoic tectonic and geomorphic evolution of the Longxi region in northeastern Tibetan Plateau interpreted from detrital zircon显示文摘The Longxi region contains different kinds of Cenozoic sediments,including eolian deposits,reworked loess,fluvial and lacustrine deposits.The provenance evolution of these sediments is of great significance in exploring the uplift,tectonic deformation and associated with geomorphic evolution of the Northeastern Tibetan Plateau.In this paper,we used the single-grain zircon provenance analysis to constrain the provenances for the Paleogene alluvial conglomerates and for the Neogene fluvial-lacustrine sediments,and compared them with results from the loess deposits since the Miocene.The results show that:(1)the Paleogene alluvial conglomerates contain a large number of detrital zircons ranging from 560 to 1100 Ma that were derived from the Yangzi Block.However,the sediments of early Miocene have much fewer zircons of this age span,which are characterized by an abundance of zircon ages in the ranges of 200-360 Ma.This indicates that the Paleogene alluvial conglomerates mainly come from the middle and/or southern West Qinling,and the early Miocene sediments are primarily from the northern West Qinling;(2)Late Neogene fluvial sediments(11.5 Ma onward)in Tianshui-Qinan region are dominated by zircon ages of 3 80-450 Ma.This zircon population is similar to that of the exposed intrusive rocks of southern part of the Liupan Mountains,implying that the southern part of Liupan Mountains probably had already uplifted by 11.5 Ma;(3)Late Miocene lacustrine sediments in Tianshui region have a zircon age spectra that is remarkably different from coeval fluvial deposits,but is similar to the zircon age distributions of the Miocene loess in Qinan region,late Miocene-Pliocene Hipparion red clay and Quaternary loess.This indicates that fine particles within these Miocene lacustrine sediments in Tianshui region may be dominated by aeolian materials.This study reveals that provenance changes of Cenozoic sediments in Tianshui-Qinan region and its geomorphic evolution are closely related to the multi-stage uplift of the Northeastern Tibetan Plateau.In particular,the major uplift of the Northern Tibetan Plateau during late Oligocene-early Miocene may have not only provided the source areas and wind dynamic conditions for the deposits of the Miocene loess,but also provided the geomorphic conditions for its accumulation. | WANG ZhiXiang LIANG MeiYan SUN YuQi DAI GaoWen | 2017 | Science China Earth Sciences2017,60,2: | 4 |
| 5 | Development of Perennial Wheat Through Hybridization Between Wheat and Wheatgrasses: A Review显示文摘 | Lei Cui Yongkang Ren Timothy D. Murray Wenze Yan Qing Guo Yuqi Niu Yu Sun Hongjie Li | 2018 | Engineering2018,4,4: | 4 |
| 6 | Radiation theory comparison for magnetoacoustic tomography with magnetic induction(MAT-MI)显示文摘Based on the principle of Lorentz force induced acoustic vibration, radiation theory comparison between acoustic point and dipole sources was conducted for magnetoacoustic tomography with magnetic induction(MAT-MI). It is proved that each acoustic source of MATMI is produced by the divergence of the magnetically induced Lorentz force, and the detected acoustic pressure is the integral of all diffraction sources inside the object.Wave clusters are produced by abrupt pressure changes at conductivity boundaries, and only the configurations in terms of shape and size of phantom models can be reconstructed. However, different from point source, positive and negative pressures are generated by the radiation pattern of dipole sources. Reverse vibration phases of wave clusters in collected waveforms and opposite polarities of borderline stripes in reconstructed images are produced at conductivity boundaries, representing the direction of conductivity changes. The experimentally collected waveforms and reconstructed images of the aluminum foil cylinder and cylindrical saline gel phantom model agree well with simulated results. The favorable results prove the validity of the radiation theory of acoustic dipole source and provide basis for further investigation of conductivity reconstruction for MAT-MI. | Xiaodong Sun Yuqi Zhou Qingyu Ma Dong Zhang | 2014 | Chinese Science Bulletin2014,59,26: | 3 |
| 7 | The cost of obsessive- compulsive disorder (OCD) in China: a multi- center cross- sectional survey based on hospitals显示文摘Background Obsessive-compulsive disorder(OCD)is considered a very debilitating disorder with severe loss of quality of life and income.Aims This study estimates the quality of life and economic consequences of OCD in China.Methods The research team interviewed 639 patients with OCD in 13 hospitals in 12 cities in China.The direct method was used to get the direct cost of OCD.Indirect costs associated with OCD were estimated using the human capital approach.Linear regression analysis was conducted for quality of life and generalised linear model analysis was conducted for total cost.Sensitivity analysis was used to analyse the uncertainty of total cost.Results The mean quality of life score for OCD was 52.78(20.46).The annual total cost of OCD per capita was 24503.78(95%CI:22621.53 to 26386.03)renminbi(RMB)(US$3465.88(95%CI:US$3199.65 to US$3732.11)).The annual cost of OCD in China was estimated to be 37.74 billion(95%CI:34.95 billion to 40.53 billion)RMB(equal to US$5.34 billion(95%CI:US$4.94 billion to US$5.73 billion)).Sensitivity analysis showed that the total annual cost of OCD in China was between 23.15 billion RMB(US$3.27 billion)and 370.00 billion RMB(US$52.33 billion).Worse social function status,more psychiatric symptoms and higher Yale Brown Obsessive-Compulsive Scale(Y-BOCS)score were associated with worse quality of life.The numbers of clinic visits and hospitalisations,socioeconomic status,education,Y-BOCS scores and age were found to be significantly associated with total cost.Conclusions OCD is associated with low quality of life and high costs in China.The findings call for concerted efforts to improve services for patients with OCD.Improvements may include early detection and diagnosis,the provision of evidence-based treatments and relapse prevention strategies. | Weili Yang Zhen Tang Xijin Wang Xiancang Ma Yuqi Cheng Bin Wang Ping Sun Wenxin Tang Jia Luo Changhong Wang Ping Li Guiyun Xu Jun Yan Vlasios Brakoulias Zhen Wang | 2021 | General Psychiatry2021,34,6: | 3 |
| 8 | Efficient single-component white light emitting diodes enabled by lanthanide ions doped lead halide perovskites via controlling Forster energy transfer and specific defect clearance显示文摘Currently,a major challenge for metal-halide perovskite light emitting diodes(LEDs)is to achieve stable and efficient white light emission due to halide ion segregation.Herein,we report a promising method to fabricate white perovskite LEDs using lanthanide(Ln^(3+))ions doped CsPbCl_(3) perovskite nanocrystals(PeNCs).First,K^(+)ions are doped into the lattice to tune the perovskite bandgap by partially substituting Cs^(+)ions,which are well matched to the transition energy of some Ln^(3+)ions from the ground state to the excited state,thereby greatly improving the Förster energy transfer efficiency from excitons to Ln3+ions.Then,creatine phosphate(CP),a phospholipid widely found in organisms,serves as a tightly binding surface-capping multi-functional ligand which regulates the film formation and enhances the optical and electrical properties of PeNC film.Consequently,the Eu^(3+)doped PeNCs based-white LEDs show a peak luminance of 1678 cd m^(-2) and a maximum external quantum efficiency(EQE)of 5.4%,demonstrating excellent performance among existing white PeNC LEDs from a single chip.Furthermore,the method of bandgap modulation and the defect passivation were generalized to other Ln^(3+)ions doped perovskite LEDs and successfully obtained improved electroluminescence(EL).This work demonstrates the comprehensive and universal strategies in the realization of highly efficient and stable white LEDs via single-component Ln^(3+)ions doped PeNCs,which provides an optimal solution for the development of low-cost and simple white perovskite LEDs. | Rui Sun Donglei Zhou Yujiao Ding Yue Wang Yuqi Wang Xinmeng Zhuang Shuainan Liu Nan Ding Tianyuan Wang Wen Xu Hongwei Song | 2022 | Light(Science & Applications)2022,11,12: | 3 |
| 9 | Transparent,stretchable,temperature-stable and self-healing ionogel-based triboelectric nanogenerator for biomechanical energy collection显示文摘A flexible and stable power supply is essential to the rapid development of wearable electronic devices.In this work,a transparent,flexible,temperature-stable and ionogel electrode-based self-healing triboelectric nanogenerator(IS-TENG)was developed.The ionogel with excellent stretchability(1,012%),high ionic conductivity(0.3 S·m^(−1))and high-temperature stability(temperature range of−77 to 250℃)was used as the electrode of the IS-TENG.The IS-TENG exhibited excellent transparency(92.1%)and stability.The output performance did not decrease when placed in a 60℃oven for 48 h.In addition,the IS-TENG behaved like a stable output in the range of−20 to 60℃.More importantly,the IS-TENG could also achieve self-healing of electrical performance at temperatures between−20 and 60℃and its output can be restored to its original state after healing.When the single-electrode IS-TENG with an area of 3 cm×3 cm was conducted under the working frequency of 1.5 Hz,the output values for open-circuit voltage,short-circuit current,short-circuit transferred charge,and maximum peak power density were 189 V,6.2μA,57 nC,and 2.17 W·m^(−2),respectively.The IS-TENG enables to harvest biomechanical energy,and drive electronic devices.Furthermore,the application of IS-TENGs as self-driven sensors for detecting human behavior was also demonstrated,showing good application prospects in the field of wearable power technology and self-driven sensing. | Weiqiang Liao Xiukun Liu Yuqi Li Xu Xu Jinxing Jiang Shaorong Lu Dequan Bao Zhen Wen Xuhui Sun | 2022 | Nano Research2022,15,3: | 2 |
| 10 | All-Climate Stretchable Dendrite-Free Zn-Ion Hybrid Supercapacitors Enabled by Hydrogel Electrolyte Engineering显示文摘Hybrid supercapacitors have shown great potentials to fulfill the demand of future diverse applications such as electric vehicles and portable/wearable electronics.In particular,aqueous zinc-ion hybrid supercapacitors(ZHSCs)have gained much attention due to their low-cost,high energy density,and environmental friendliness.Nevertheless,typical ZHSCs use Zn metal anode and normal liquid electrolyte,causing the dendrite issue,restricted working temperature,and inferior device flexibility.Herein,a novel flexible Zn-ion hybrid supercapacitor(FZHSC)is developed by using activated carbon(AC)anode,δ-MnO_(2) cathode,and innovative PVA-based gel electrolyte.In this design,heavy Zn anode and its dendrite issue are avoided and layered cathode with large interlayer spacing is employed.In addition,flexible electrodes are prepared and integrated with an anti-freezing,stretchable,and compressible hydrogel electrolyte,which is attained by simultaneously using glycerol additive and freezing/thawing technique to regulate the hydrogen bond and microstructure.The resulting FZHSC exhibits good rate capability,high energy density(47.86 Wh kg^(−1);3.94 mWh cm^(−3)),high power density(5.81 kW kg^(−1);480 mW cm^(−3)),and excellent cycling stability(~91%capacity retention after 30000 cycles).Furthermore,our FZHSC demonstrates outstanding flexibility with capacitance almost unchanged even after various continuous shape deformations.The hydrogel electrolyte still maintains high ionic conductivity at ultralow temperatures(≤−30℃),enabling the FZHSC cycled well,and powering electronic timer robustly within an all-climate temperature range of−30~80℃.This work highlights that the promising Zn metal-free aqueous ZHSCs can be designed with great multifunctionality for more practical application scenarios. | Yuqi Jiang Kun Ma Meiling Sun Yuanyuan Li Jinping Liu | 2023 | Energy & Environmental Materials2023,6,2: | 2 |
| 11 | Degradable Hybrid CuS Nanoparticles for Imaging-Guided Synergistic Cancer Therapy via Low-Power NIR-II Light Excitation显示文摘Near-infrared(NIR)-II light-excitable photonic agents capable of generating tumor hyperthermia and cytotoxic free radicals are promising for synergistic phototherapy of tumors.However,the lack of NIR-II excitable agents makes it challenging to achieve combinational tumor phototherapy.Here,the authors have reported on a tumor-targeting and degradable hybrid copper sulfide(CuS)nanoparticle(AIBA@CuS-FA)via loading a hydrophilic Azo initiator(AIBA)into an amphiphilic lipid-encapsulating CuS nanoparticle.AIBA@CuS-FA shows high photothermal conversion efficiency(PCE≈47.5%)at 1064 nm,enabling heat production to trigger tumor hyperthermia and thermal decomposition of AIBA into cytotoxic free alkyl radicals upon irradiation with a 1064-nm laser under low-power density(0.5 W/cm2).Moreover,alkyl radicals can drive degradation of AIBA@CuS-FA and embedded CuS nanodisks,releasing Cu^(2+)ions that can catalyze a Fenton-like reaction for hydroxyl radical(•OH)production to promote tumor therapy.Findings demonstrate promise for combinational photothermal therapy(PTT),oxygen-independent alkyl radical therapy,and chemodynamic therapy(CDT)of tumors. | Yidan Sun Hua Shi Xiaoyang Cheng Luyan Wu Yuqi Wang Zhengyang Zhou Jian He Hong-Yuan Chen Deju Ye | 2021 | CCS Chemistry2021,3,5: | 2 |
| 12 | Prevalence of transmitted drug resistance mutations among patients infected with human immunodeficiency virus type 1 (HIV-1) in Henan Province, China显示文摘To the Editor:Even with the emergence of highly active antiretroviral therapy,human immunodeficiency virus type 1(HIV-1)remains a serious public health problem worldwide.The widespread use of antiretroviral therapy(ART)has,on the one hand,significantly improved life expectancy in patients infected with HIV-1;on the other hand,it has inevitably brought along with it a difficult problem—viral resistance.Viral resistance is a common phenomenon evolutionarily,particularly in patients with poor adherence and suboptimal drug levels. | Jinjin Liu Xiaohua Zhang Mingjie Hou Shuguang Wei Jie Ma Lixia Xu Xuan Yang Yan Sun Chunli Liu Qingxia Zhao Yuqi Huo | 2022 | Chinese Medical Journal2022,135,22: | 2 |
| 13 | Traditional Chinese Medicine guidelines for coronavirus disease 2019显示文摘OBJECTIVE:To summarize the evidence from Traditional Chinese Medicine(TCM)practice in the treatment of coronavirus disease 2019(COVID-19)and provide timely clinical practice guidance.METHODS:The guidelines were developed in accordance with the World Health Organization rapid guideline process.The evidence on TCM for COVID-19 from published guidelines,direct and indirect published clinical evidence,first hand clinical data,and expert experience and consensus were collected.The grading of recommendations assessment,development and evaluation(GRADE)method was used to grade the evidence and make the recommendations.RESULTS:Based on the available evidence,the guidelines recommended 17 Chinese medicines for COVID-19:2 Chinese herbal granules,7 Chinese patent medicines,and 8 Chinese herbal injections.CONCLUSION:As the literature search was conducted on March,any subsequent versions of these guidelines require an up-to-date literature review.We hope that the evidence summary in these guidelines will be helpful in global efforts to address COVID-19. | Liang Ning Ma Yanfang Wang Jingya Li Huizhen Wang Xiaohui Jiao Liwen Liu Bin Ma Yan Zhao Chen Luo Xufei Zhao Siya Lu Meng Cao Jin Hu Wenpin Zhang Hairong Liu Guoxiu Lu Cheng Liu Mengyu Li Li Han Xuejie Liu Yuqi Wang Liying Zhao Xueyao Wei Dongfeng Bai Jing Sun Mingyu Yang Yong Wu Xiaodan Chen Yaolong Shi Nannan Wang Yanping Wang Yongyan | 2020 | Journal of Traditional Chinese Medicine2020,40,6: | 2 |
| 14 | A bi-leve model of dynamic traffic signal control withcontinuum approximation显示文摘 | Ke Han Yuqi Sun Hongcheng Liu et aI | 2015 | transportation research part C2015,55,: | 1 |
| 15 | Moirésuperlattice engineering of two-dimensional materials for electrocatalytic hydrogen evolution reaction显示文摘Vertically stacking two-dimensional(2D)materials with small azimuthal deviation or lattice mismatch generate distinctive global structural periodicity and symmetry,revealed as the moirésuperlattices(MSLs).Manipulating the interlayer twist angle enables the modification of the electronic structure of 2D materials to explore the advanced applications.Although extraordinary progress has been achieved in the unique structure and emergent properties of MSLs,the investigation of the catalytic applications of MSLs materials is still in its infancy.It is therefore very urgent to summarize the advanced development of MSLs in the field of catalysis.In this review,we firstly summarize the advanced fabrication and high-resolution characterization techniques of the MSLs materials,as well as their novel properties related to catalysis represented by electrocatalytic hydrogen evolution reaction(HER).Then,all the MSLs materials such as MoS_(2),WS_(2),and Ru serving as electrocatalysts for HER are further reviewed in detail.Finally,we outline the current challenges as well as the experimental and theoretical strategies to advance the development of function-oriented MSLs materials for catalysis.This review aims to provide profound insight into the wide applications of this novel material platform in catalytic field. | Yang Li Yuqi Hua Ning Sun Shijie Liu Hengxu Li Cheng Wang Xinyu Yang Zechao Zhuang Longlu Wang | 2023 | Nano Research2023,16,7: | 1 |
| 16 | Preliminary research of crank - group driving mechanism显示文摘 | Cao Jujiang Wang Yuqi Sun Jiwei | 2012 | Applied Mechanics and Materials Mechanical and Electrical Technology IV2012,,: | 1 |
| 17 | Effect of organic substrates on available elemental contents in nutrient solution显示文摘 | Yansong Ao Min Sun Yuqi Li | 2008 | Bioresource Technology2008,99,11: | 1 |
| 18 | REE bound DNA in natural plant显示文摘 | Yuqi Wang Ping Jiang Fanqing Guo Zhiyong Zhang Jingxin Sun Lei Xu Guoyin Cao | 1999 | Science in China Series B: Chemistry1999,,4: | 1 |
| 19 | REE bound polysaccharides in leaves of Dicranopteris dichotoma by MAA显示文摘 | Yuqi Wang Jingxin Sun Hongmin Chen Fanqing Guo Lei Xu Guoyin Cao | 1998 | Science in China Series B: Chemistry1998,,3: | 1 |
| 20 | Expression and purification of a novel ZNF191 zinc finger protein显示文摘 | Yuqi Liu Long Yu Wenhao Yu Shaolin Shi Bingyun Sun Guojun Wu Zhongxian Huang | 1999 | Science in China Series B: Chemistry1999,,3: | 1 |