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| 1 | Th22 cells are associated with hepatocellular carcinoma development and progression显示文摘Objective: IL-22-producing CD4+ T helper cells(Th22 cells) have been identified as major inducers of tissue inflammation and immune responses. Currently, no previous study explored the role of Th22 cells in the pathogenesis of hepatocellular carcinoma(HCC). The study aimed to determine the biological function of Th22 cells and its effector IL-22 in HCC patients.Methods: Forty-five HCC patients and 19 healthy controls were recruited and their peripheral blood was collected. The fresh HCC tissues, adjacent HCC tissues and ten normal liver tissues were also collected. Flow cytometry analysis was used to determine the frequencies of circulating Th22 cells and Th17 cells. Serum IL-22 levels were tested by enzyme-linked immunosorbent assay(ELISA). Immunohistochemical staining and real-time polymerase chain reaction(PCR) were used to detect IL-22 protein and mRNA in tissues specimens, respectively.Results: Circulating Th22 cells, Th17 cells and serum IL-22 levels were significantly elevated in HCC patients compared with those of healthy controls(P<0.001). Th22 cells were showed to be positively correlated with IL-22 in HCC patients(P<0.05), but not in healthy controls. No significant differences were found in HCC patients with HBeAg positivity or negativity in term of Th22 cells and serum IL-22 levels. The expression of IL-22 protein and mRNA was highest in HCC tissues, followed by adjacent HCC tissues and normal liver tissues. Furthermore, Th22 cells, serum IL-22 levels and IL-22 mRNA were elevated at stage III-IV compared with stage I-II of HCC(P<0.05).Conclusions: Elevation of circulating Th22 cells and IL-22 may be implicated in the pathogenesis of HCC, and potentially be cellular targets for therapeutic intervention. | Shanyu Qin Shijia Ma Xiaoli Huang Donghong Lu You Zhou Haixing Jiang | 2014 | Chinese Journal of Cancer Research2014，26，2： | 25 |
| 2 | A New Critical Nitrogen Dilution Curve for Rice Nitrogen Status Diagnosis in Northeast China显示文摘In-season diagnosis of crop nitrogen(N) status is crucial for precision N management. Critical N(N_c) dilution curve and N nutrition index(NNI) have been proposed as effective methods to diagnose N status of different crops. The N_c dilution curves have been developed for indica rice in the tropical and temperate zones and japonica rice in the subtropical-temperate zone, but they have not been evaluated for short-season japonica rice in Northeast China. The objectives of this study were to evaluate the previously developed N_c dilution curves for rice in Northeast China and to develop a more suitable N_c dilution curve in this region. A total of17 N rate experiments were conducted in Sanjiang Plain, Heilongjiang Province in Northeast China from 2008 to 2013. The results indicated that none of the two previously developed N_c dilution curves was suitable to diagnose N status of the short-season japonica rice in Northeast China. A new N_c dilution curve was developed and can be described by the equation N_c = 27.7 W^(-0.34) if W ≥ 1 Mg dry matter(DM) ha^(-1) or N_c = 27.7 g kg^(-1) DM if W < 1 Mg DM ha^(-1), where W is the aboveground biomass. This new curve was lower than the previous curves. It was validated using a separate dataset, and it could discriminate non-N-limiting and N-limiting nutritional conditions. Additional studies are needed to further evaluate it for diagnosing N status of different rice cultivars in Northeast China and develop efficient non-destructive methods to estimate NNI for practical applications. | HUANG Shanyu MIAO Yuxin CAO Qiang YAO Yinkun ZHAO Guangming YU Weifeng SHEN Jianning YU Kang Georg BARETH | 2018 | Pedosphere2018，28，5： | 10 |
| 3 | Quantitative nanoscale mapping of three-phase thermal conductivities in filled skutterudites via scanning thermal microscopy显示文摘In the last two decades, a nano structuring paradigm has been successfully applied in a wide range of thermoelectric materials, resulting in significant reduction in thermal conductivity and superior thermoelectric performance. These advances, however, have been accomplished without directly investigating the local thermoelectric properties, even though local electric current can be mapped with high spatial resolution. In fact, there still lacks an effective method that links the macroscopic thermoelectric performance to the local micro structures and properties. Here, we show that local thermal conductivity can be mapped quantitatively with good accuracy, nanometer resolution and one-to-one correspondence to the micro structure using a three-phase skutterudite as a model system. Scanning thermal microscopy combined with finite element simulations demonstrate close correlation between sample conductivity and probe resistance,enabling us to distinguish thermal conductivities spanning orders of magnitude, yet resolving thermal variation across a phase interface with small contrast. The technique thus provides a powerful tool to correlate local thermal conductivities, micro structures and macroscopic properties for nano structured materials in general and nano structured thermo electrics in particular. | ehsan nasr esfahani feiyue ma shanyu wang yun ou jihui yang jiangyu li | 2018 | National Science Review2018，5，1： | 6 |
| 4 | Heterogeneously supported pseudo-single atom Pt as sustainable hydrosilylation catalyst显示文摘 | Huachao Zai Yizhou Zhao Shanyu Chen Lei Ge Changfeng Chen Qi Chen Yujing Li | 2018 | Nano Research2018，11，5： | 6 |
| 5 | Toward an RSU-unavailable Lightweight Certificateless Key Agreement Scheme for VANETs显示文摘Vehicle ad-hoc networks have developed rapidly these years,whose security and privacy issues are always concerned widely.In spite of a remarkable research on their security solutions,but in which there still lacks considerations on how to secure vehicleto-vehicle communications,particularly when infrastructure is unavailable.In this paper,we propose a lightweight certificateless and oneround key agreement scheme without pairing,and further prove the security of the proposed scheme in the random oracle model.The proposed scheme is expected to not only resist known attacks with less computation cost,but also as an efficient way to relieve the workload of vehicle-to-vehicle authentication,especially in no available infrastructure circumstance.A comprehensive evaluation,including security analysis,efficiency analysis and simulation evaluation,is presented to confirm the security and feasibility of the proposed scheme. | SONG Jun HE Chunjiao ZHANG Lei TANG Shanyu ZHANG Huanguo | 2014 | China Communications2014，11，9： | 5 |
| 6 | Effects of Artificial Aging on Physiological Characteristics of Rice Seeds with Different Dormancy Characteristics显示文摘In this study,two indica varieties with different dormancy characteristics [4 K58( II-32 B dormant),4 K59( II-32 B) ] and their F2 seeds( C178,C179) obtained through hybridization with sterile line( II-32 A) were used as materials. Different aged seeds( 0,3,6 and 9 d) of these four varieties were acquired by artificial accelerated aging method. Effects of artificial aging on malondialdehyde( MDA) content and catalase( CAT),ascorbate peroxidase( APX),peroxidase( POD) and superoxide dismutase( SOD) activity were investigated. The results showed that with the prolongation of aging time,MDA contents of these four rice varieties increased significantly,while the activity of antioxidant enzymes decreased dramatically. Besides,MDA contents and SOD,CAT and APX activity of the two inbred lines were significantly lower than those of the hybrid varieties. In addition,the activity of antioxidant enzymes in 4 K58 and C178 was significantly lower than that in 4 K59 and C179,respectively. This study indicated that artificial aging treatment significantly inhibited the activity of antioxidant system in seeds,improved membrane lipid peroxidation degree,and thus aggravated the deterioration of seeds. In addition,it also suggested that rice seeds with dormant property were more intolerant to storage. | Dongdong CAO Shanyu CHEN Yutao HUANG Yebo QIN Guanhai RUAN | 2019 | Agricultural Biotechnology2019，8，1： | 5 |
| 7 | Classification of rational holomorphic maps from B^2 into B^N with degree 2显示文摘Rational proper holomorphic maps from the unit ball in C 2 into the unit ball C N with degree 2 are classified, up to automorphisms of balls. | JI ShanYu 1 & ZHANG Yuan 2 1 Department of Mathematics, University of Houston, Houston, TX 77204, USA 2 Department of Mathematics, University of California at San Diego, La Jolla, CA 92093, USA | 2009 | Science China Mathematics2009，52，12： | 4 |
| 8 | Printable Aligned Single-Walled Carbon Nanotube Film with Outstanding Thermal Conductivity and Electromagnetic Interference Shielding Performance显示文摘Ultrathin,lightweight,and flexible aligned single-walled carbon nanotube(SWCNT)films are fabricated by a facile,environmentally friendly,and scalable printing methodology.The aligned pattern and outstanding intrinsic properties render“metal-like”thermal conductivity of the SWCNT films,as well as excellent mechanical strength,flexibility,and hydrophobicity.Further,the aligned cellular microstructure promotes the electromagnetic interference(EMI)shielding ability of the SWCNTs,leading to excellent shielding effectiveness(SE)of~39 to 90 dB despite a density of only~0.6 g cm^(−3) at thicknesses of merely 1.5-24μm,respectively.An ultrahigh thickness-specific SE of 25693 dB mm^(−1) and an unprecedented normalized specific SE of 428222 dB cm^(2)g^(−1) are accomplished by the freestanding SWCNT films,significantly surpassing previously reported shielding materials.In addition to an EMI SE greater than 54 dB in an ultra-broadband frequency range of around 400 GHz,the films demonstrate excellent EMI shielding stability and reliability when subjected to mechanical deformation,chemical(acid/alkali/organic solvent)corrosion,and high-/low-temperature environments.The novel printed SWCNT films offer significant potential for practical applications in the aerospace,defense,precision components,and smart wearable electronics industries. | Zhihui Zeng Gang Wang Brendan F.Wolan Na Wu Changxian Wang Shanyu Zhao Shengying Yue Bin Li Weidong He Jiurong Liu Joseph W.Lyding | 2022 | Nano-Micro Letters2022，14，11： | 4 |
| 9 | Production and measurement of Bose-Einstein condensate of ^(87)Rb atomic gas显示文摘The research platform for Bose-Einstein condensate in 87 Rb atomic gas,which is composed of a double MOT configuration and a QUIC trap,was reported.The properties of the condensate were measured both in time-of-flight and in tight confinement by the absorption imaging method.The measurements agreed with the criterions of Bose-Einstein condensation phase transition.About 2×10 5 atoms were pure condensed. | XU Zhen ,ZHOU ShuYu,ZHOU ShanYu&WANG YuZhu Key Laboratory for Quantum Optics,Shanghai Institute of Optics and Fine Mechanics,Chinese Academy of Sciences,Shanghai 201800,China | 2008 | Science China(Physics,Mechanics & Astronomy)2008，51，1： | 3 |
| 10 | Rational holomorphic maps from B^2 into B^N with degree 2显示文摘Rational proper holomorphic maps from the unit ball in C2 into the unit ball CN with degree 2 are studied. Any such map must be equivalent to one of the four types of maps. | CHEN Zhihua, Jl Shanyu & XU Dekang Department of Mathematics, Tongji University, Shanghai 200092, China Department of Mathematics, University of Houston, Houston, TX 77204, USA | 2006 | Science China Mathematics2006，49，11： | 3 |
| 11 | Steganalysis of Low Embedding Rates LSB Speech Based on Histogram Moments in Frequency Domain显示文摘As wavelet packet transform is able to focus on minute change of signals, this study proposes an analytic approach of low embedding steganograpy based on high order Histogram moments in frequency domain(HMFD), which provides a key solution to the feature selection and extraction of HMFD. The detection results are tested with the LSB matching steganograpy of different embedding rates in speech signals, respectively, it is proved that the detection performance with HMFD applied is greater than that of histogram statistical moments.HMFD by Wavelet packet decomposition(WPD) can effectively detect low embedding rates Least significant bit(LSB) speech steganography, its accuracy can be 60.8%while the embedding rate is only 3%. | YANG Wanxia TANG Shanyu LI Miaoqi CHENG Yongfeng ZHOU Zhili | 2017 | Chinese Journal of Electronics2017，26，6： | 3 |
| 12 | Identification of banana fusarium wilt using supervised classification algorithms with UAV-based multi-spectral imagery显示文摘The disease of banana Fusarium wilt currently threatens banana production areas all over the world.Rapid and large-area monitoring of Fusarium wilt disease is very important for the disease treatment and crop planting adjustments.The objective of this study was to evaluate the performance of supervised classification algorithms such as support vector machine(SVM),random forest(RF),and artificial neural network(ANN)algorithms to identify locations that were infested or not infested with Fusarium wilt.An unmanned aerial vehicle(UAV)equipped with a five-band multi-spectral sensor(blue,green,red,red-edge and near-infrared bands)was used to capture the multi-spectral imagery.A total of 139 ground sample-sites were surveyed to assess the occurrence of banana Fusarium wilt.The results showed that the SVM,RF,and ANN algorithms exhibited good performance for identifying and mapping banana Fusarium wilt disease in UAV-based multi-spectral imagery.The overall accuracies of the SVM,RF,and ANN were 91.4%,90.0%,and 91.1%,respectively for the pixel-based approach.The RF algorithm required significantly less training time than the SVM and ANN algorithms.The maps generated by the SVM,RF,and ANN algorithms showed the areas of occurrence of Fusarium wilt disease were in the range of 5.21-5.75 hm2,accounting for 36.3%-40.1%of the total planting area of bananas in the study area.The results also showed that the inclusion of the red-edge band resulted in an increase in the overall accuracy of 2.9%-3.0%.A simulation of the resolutions of satellite-based imagery(i.e.,0.5 m,1 m,2 m,and 5 m resolutions)showed that imagery with a spatial resolution higher than 2 m resulted in good identification accuracy of Fusarium wilt.The results of this study demonstrate that the RF classifier is well suited for the identification and mapping of banana Fusarium wilt disease from UAV-based remote sensing imagery.The results provide guidance for disease treatment and crop planting adjustments. | Huichun Ye Wenjiang Huang Shanyu Huang Bei Cui Yingying Dong Anting Guo Yu Ren Yu Jin | 2020 | International Journal of Agricultural and Biological Engineering2020，13，3： | 3 |
| 13 | Audio steganography with AES for real-time covert voice over internet protocol communications显示文摘As a popular real-time service on the Internet,Voice over Internet Protocol(VoIP)communication attracts more and more attention from the researchers in the information security field.In this study,we proposed a VoIP steganographic algorithm with variable embedding capacities,incorporating AES and key distribution,to realize a real-time covert VoIP communication.The covert communication system was implemented by embedding a secret message encrypted with symmetric cryptography AES-128 into audio signals encoded by PCM codec.At the beginning of each VoIP call,a symmetric session key(SK)was assigned to the receiver with a session initiation protocol-based authentication method.The secret message was encrypted and then embedded into audio packets with diferent embedding algorithms before sending them,so as to meet the realtime requirements of VoIP communications.For each audio packet,the embedding capacity was calculated according to the specific embedding algorithm used.The encryption and embedding processes were almost synchronized.The time cost of encryption was so short that it could be ignored.As a result of AES-based steganography,observers could not detect the hidden message using simple statistical analysis.At the receiving end,the corresponding algorithm along with the SK was employed to retrieve the original secret message from the audio signals.Performance evaluation with state-of-the-art network equipment and security tests conducted using the Mann-Whitney-Wilcoxon method indicated that the proposed steganographic algorithm is secure,efective,and robust. | TANG ShanYu JIANG YiJing ZHANG LiPing ZHOU ZhangBing | 2014 | Science China(Information Sciences)2014，57，3： | 2 |
| 14 | Bismuth-doped glass microsphere lasers显示文摘In this work, a hybrid structure consisting of a multicomponent germanate glass microsphere containing bismuth as a gain medium is proposed and presented. The bismuth-doped germanate glass microspheres were fabricated from a glass fiber tip with no precipitation of the bismuth metal. Coupling with a fiber taper, the bismuth-doped microsphere single-mode laser was observed to lase at around 1305.8 nm using 808 nm excitation. The low threshold of absorbed pump power at 215 μW makes this microlaser appealing for various applications, including tunable lasers for a range of purposes in telecommunication, biomedical, and optical information processing. | ZAIJIN FANG SíLE NIC CHORMAIC SHANYU WANG XIN WANG JIBO YU YUXUAN JIANG JIANRONG QIU PENGFEI WANG | 2017 | Photonics Research2017，5，6： | 2 |
| 15 | Effect of carbon and nitrogen ratio control on Artemia growth, water quality, biofloc microbial diversity under high salinity and zero-water exchange culture condition显示文摘Biofloc technology has been applied successfully in the intensive aquaculture of several fish and shrimp species. The growth of heterotrophic microorganisms can be stimulated through adding extra carbon, which reduces the nitrogen level in the water and provides microbial protein to the animals. However, most of the studies and practical applications have been conducted in freshwater and marine environment. This paper focused on brine shrimp Artemia that lives in high salinity environment together with other halophilic or halotolerant microorganisms. The effect of carbon supplementation on Artemia growth, water quality, and microbial diversity of biofl ocs was studied in the closed culture condition without any water exchange. The salinity of the culture medium was 100. A 24-d culture trial was conducted through supplementing sucrose at carbon/nitrogen (C/N) ratio of 5, 15, and 30 (Su5, Su15, and Su30), respectively. The culture without adding sucrose was used as a control. Artemia was fed formulated feed at a feeding ration of 60% recommended feeding level. The results showed that sucrose supplementation at higher C/N ratio (15 and 30) signifi cantly improved the Artemia survival, growth and water quality ( P <0.05). Addition of sucrose at C/N ratio of 15 and 30 significantly increased biofloc volume (BFV)( P <0.05). The Illumina MiSeq sequencing analysis showed that supplementing carbon at C/N ratio of 15 had a better total bacterial diversity and richness, and shaped the microbial composition at genera level. This study should provide information for studying the mechanism of biofloc technology and its application in high salinity culture conditions. | WANG Shanyue CUI Xueping XU Ruyi GAO Meirong SUI Liying | 2019 | Journal of Oceanology and Limnology2019，37，5： | 2 |
| 16 | Covert voice over internet protocol communications based on spatial model显示文摘This paper presents a new spatial steganography model for covert communications over voice over internet protocol(Vo IP), providing a solution to the issue of increasing the capacity of covert Vo IP channels without compromising the imperceptibility of the channels. Drawing from Orthogonal Modulation Theory in communications, the model introduced two concepts, orthogonal data hiding features and data hiding vectors, to covert Vo IP communications. By taking into account the variation characteristics of Vo IP audio streams in the time domain, a hiding vector negotiation mechanism was suggested to achieve dynamic self-adaptive steganography in media streams. Experimental results on Vo IP steganography show that the proposed steganographic method effectively depicted the spatial and temporal characteristics of Vo IP audio streams, and enhanced robustness against detection of steganalysis tools, thereby improving the security of covert Vo IP communications. | HUANG YongFeng TANG ShanYu | 2016 | Science China(Technological Sciences)2016，59，1： | 2 |
| 17 | Soil respiration response to precipitation reduction in a grassland and a Mongolian pine plantation in semi-arid northeast China显示文摘Climate change is predicted to alter global precipitation regimes.However,the response of soil carbon and nitrogen cycles and soil microorganisms to precipitation reduction is poorly understood but is dependent on ecosystem type.To evaluate the impacts of reduced precipitation on soil respiration,soil inorganic nitrogen(i.e.,NH4^+–N and NO3^-–N),nitrogen mineralization,and soil microbial community composition,a precipitation manipulation experiment was initiated in a Mongolian pine plantation and a naturally restored grassland in semi-arid northeast China.Precipitation reduction led to decreases of soil respiration rates by 14 and 8%in 2014 and 2015 in the Mongolian pine plantation but no changes in the grassland.Soil inorganic nitrogen,ammonification and nitrification rate,and soil phospholipids fatty acids were not significantly changed by reduced precipitation but significantly differed between the two ecosystems and among growing seasons.Our results suggest that the impacts of precipitation reduction on soil respiration were different between the Mongolian pine plantation and the grassland,and that ecosystem type and growing season had more pronounced impacts on soil carbon and nitrogen cycles. | Yalin Hu Jintao Li Shanyu Zhao Dehui Zeng | 2019 | Journal of Forestry Research2019，30，5： | 2 |
| 18 | Steganogra-phy in inactive frames of VoIP streams encoded by source codec显示文摘 | Huang Yongfeng Yuan Jian Tang Shanyu | 2011 | IEEE Transactions on Information Forensics and Security2011，6，2： | 1 |
| 19 | A communication- computation efficient group key algorithm for large and dynamic groups显示文摘 | ZHENG SHANYU MANZ D ALVES-FOSS J | 2007 | Computer Networks2007，51，1： | 1 |
| 20 | Active canopy sensor-based precision N management strategy for rice显示文摘 | Yinkun Yao Yuxin Miao Shanyu Huang Lei Gao Xiaobo Ma Guangming Zhao Rongfeng Jiang Xinping Chen Fusuo Zhang Kang Yu Martin Gnyp Georg Bareth Cheng Liu Liqin Zhao Wen Yang Huamin Zhu | 2012 | Agronomy for Sustainable Development2012，，4： | 1 |
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