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| 1 | Yizhi Xingnao prescription improves the cognitive function of patients after a transient ischemic attack显示文摘Patients with mild cognitive impairment after a transient ischemic attack were included in this study. They were treated with Yizhi Xingnao prescription, ergoloid mesylates or aspirin for 60 days. Evaluation using the Montreal Cognitive Assessment Scale showed that cognitive function was significantly improved in all patients, especially after the combined treatment of Yizhi Xingnao and aspirin. The scores from the Montreal Cognitive Assessment Scale were improved overall and the effective treatment rate was as high as 79%, which was higher than patients treated with a combination of ergoloid mesylates and aspirin, or aspirin alone. Our experimental findings indicate that Yizhi Xingnao prescription can improve mild cognitive impairment after a transient ischemic attack, and that it is more effective than ergoloid mesylates. | Donglin Jiang Xing Chu Lingling Hu Shengyang Jiang Feng Hu Junming Sun Chengwan Li | 2012 | Neural Regeneration Research2012，7，6： | 2 |
| 2 | Convection-Diffusion Model for Radon Migration in a Three-Dimensional Confined Space in Turbulent Conditions显示文摘Convection and diffusion are the main factors affecting radon migration.In this paper,a coupled diffusion-convection radon migration model is presented taking into account turbulence effects.In particular,the migration of radon is simulated in the framework of the k-εturbulence model.The model equations are solved in a complex 3D domain by the finite element method(FEM).Special attention is paid to the case study about radon migration in an abandoned air defense shelter(AADS).The results show that air convection in a confined space has a great influence on the radon migration and the radon concentration is inversely proportional to the wind speed. | Shengyang Feng Dongbo Xiong Guojie Chen Yu Cui Puxin Chen | 2020 | Fluid Dynamics & Materials Processing2020，16，3： | 1 |
| 3 | The bacterial effector AvrRxo1 inhibits vitamin B6 biosynthesis to promote infection in rice显示文摘Xanthomonas oryzae pv.oryzicola(Xoc),which causes rice bacterial leaf streak,invades leaves mainly through stomata,which are often closed as a plant immune response against pathogen invasion.How Xoc overcomes stomatal immunity is unclear.Here,we show that the effector protein AvrRxo1,an ATPdependent protease,enhances Xoc virulence and inhibits stomatal immunity by targeting and degrading rice OsPDX1(pyridoxal phosphate synthase),thereby reducing vitamin B6(VB6)levels in rice.VB6 is required for the activity of aldehyde oxidase,which catalyzes the last step of abscisic acid(ABA)biosynthesis,and ABA positively regulates rice stomatal immunity against Xoc.Thus,we provide evidence supporting a model in which a major bacterial pathogen inhibits plant stomatal immunity by directly targeting VB6 biosynthesis and consequently inhibiting the biosynthesis of ABA in guard cells to open stomata.Moreover,AvrRxo1-mediated VB6 targeting also explains the poor nutritional quality,including low VB6 levels,of Xoc-infected rice grains. | Haifeng Liu Chongchong Lu Yang Li Tao Wu Baogang Zhang Baoyou Liu Wenjie Feng Qian Xu Hansong Dong Shengyang He Zhaohui Chu Xinhua Ding | 2022 | Plant Communications2022，3，3： | 1 |
| 4 | Reservoir characteristics and genetic differences between the second and fourth members of Sinian Dengying Formation in northern Sichuan Basin and its surrounding areas显示文摘This study investigated the characteristics and genesis of reservoirs in the 2^(nd) and 4^(th) members of Sinian Dengying Formation in northern Sichuan and its surrounding areas, on the basis of outcrop, drilling cores and thin section observation and geochemical analysis. The reservoirs of 2^(nd) member are distributed in the middle part of the stratum. The reservoir quality is controlled by supergene karst and the distribution of mound-shoal complex. The bedded elongated isolated algal framework solution-cave and the residual 'grape-lace' cave, which are partially filled with multi-stage dolosparite, constituted the main reservoir space of the 2^(nd) member. There is no asphalt distribution in the pores. The pore connectivity is poor, and the porosity and permeability of the reservoir is relatively low. The reservoirs of 4^(th) member were distributed in the upper and top part of the stratum. The reservoir quality is controlled by burial dissolution and the distribution of mound-shoal complex. The bedded algal framework solution-pores or caves, intercrystalline pores and intercrystalline dissolved pores constituted the main reservoir space of the 4^(th) member. It's partially filled with asphalt and quartz, without any dolosparite fillings in the pores and caves. The pore connectivity is good. Most of the 4^(th) member reservoirs had medium-low porosity and low permeability, and, locally, medium-high porosity and medium permeability. Affected by the development of mound-shoal complex and heterogeneous dissolution, the platform margin along Ningqiang, Guangyuan, Jiange and Langzhong is the most favorable region for reservoir development. Deep buried Dengying Formation in the guangyuan and langzhong areas should be the most important hydrocarbon target for the future exploration. | LI Yong WANG Xingzhi FENG Mingyou ZENG Deming XIE Shengyang FAN Rui WANG Liangjun ZENG Tao YANG Xuefei | 2019 | Petroleum Exploration and Development2019，46，1： | 1 |
| 5 | Probing of coupling effect induced plasmonic charge accumulation for water oxidation显示文摘A key issue for redox reactions in plasmon-induced photocatalysis, particularly for water oxidation, is the concentration of surface-accumulating charges(electrons or holes) at a reaction site for artificial photosynthesis. However, where plasmonic charge accumulated at a catalyst’s surface, and how to improve local charge density at active sites, remains unknown because it is difficult to identify the exact spatial location and local density of the plasmon-induced charge, particularly with regard to holes. Herein, we show that at the single particle level, plasmon-coupling-induced holes can be greatly accumulated at the plasmonic Au nanoparticle dimer/TiO_(2) interface in the nanogap region, as directly evidenced by the locally enhanced surface photovoltage. Such an accumulation of plasmonic holes can significantly accelerate the water oxidation reaction(multi-holes involved) at the interfacial reaction site, with nearly one order of magnitude enhancement in photocatalytic activities compared to those of highly dispersed Au nanoparticles on TiO_(2). Combining Kelvin probe force microscopy and theoretical simulation, we further clarified that the local accumulated hole density is proportional to the square of the local near-field enhancement. Our findings advance the understanding of how charges spatially distribute in plasmonic systems and the specific role that local charge density at reaction sites plays in plasmonic photocatalysis. | Yuying Gao Feng Cheng Weina Fang Xiaoguo Liu Shengyang Wang Wei Nie Ruotian Chen Sheng Ye Jian Zhu Hongyu An Chunhai Fan Fengtao Fan Can Li | 2021 | National Science Review2021，8，6： | 0 |
| 6 | Characteristics of “Guangyuan-Wangcang” trough during Late Middle Permian and its petroleum geological significance in northern Sichuan Basin, SW China显示文摘Based on outcrop characteristics, combined with regional tectonic background, drilling and geophysical data, the sedimentary characteristics of the Middle Permian Maokou Formation in the northern Sichuan Basin was studied by means of macroscopic and microscopic observation, geochemical element test, total organic carbon content and vitrinite reflectance measurement. There is a set of deep-water sediments rich in organic matter in the Guangyuan-Wangcang area of northern Sichuan during the late depositional period of the Middle Permian Maokou Formation. The strata are distributed from northwest to southeast, with thickness of 10–30 m, mainly composed of siliceous rocks and siliceous mudstones, intercalated with gravity flow deposits. Siliceous rocks and siliceous mudstones are characterized by thin single layer, flat bedding and rich siliceous radiolarians, calthrop and brachiopod with small body and thin shell, belonging to the typical sedimentary characteristics of deep-water trough facies. The contents of Cu, Co, Mo, Ni and the ratio of Ni to Co in the geochemical tests all indicate that the siliceous rocks are products of deep-water reducing environment. The TOC value ranges from 3.21% to 8.19%, with an average of 5.53%, indicating that the siliceous rocks have good hydrocarbon generation ability. The south side of the trough is in platform margin facies with high energy, and the sediments are mainly thick massive micritic-calcsparite biogenic(clastic) limestone, which is conducive to the formation and evolution of the reservoir. During the late sedimentary period of the Maokou Formation, the northward subduction and extension of the oceanic crust at the northwestern margin of the Yangtze Plate provided the internal dynamic conditions for the formation of the 'Guangyuan-Wangcang' trough. According to the location, sedimentary characteristics and formation dynamics of the trough, it is similar to the 'Kaijiang-Liangping' trough during Late Permian proposed by previous researchers. It is believed that the 'Kaijiang-Liangping' trough already had its embryonic form during the Late Middle Permian. | WANG Xingzhi LI Bo YANG Xiyan WEN Long XU Liang XIE Shengyang DU Yao FENG Mingyou YANG Xuefei WANG Yaping PEI Senqi | 2021 | Petroleum Exploration and Development2021，48，3： | 0 |
| 7 | Expert consensus on prevention and cardiopulmonary resuscitation for cardiac arrest in COVID-19显示文摘Background:Cardiopulmonary resuscitation(CPR)strategies in COVID-19 patients differ from those in patients suffering from cardiogenic cardiac arrest.During CPR,both healthcare and non-healthcare workers who provide resuscitation are at risk of infection.The Working Group for Expert Consensus on Prevention and Cardiopulmonary Resuscitation for Cardiac Arrest in COVID-19 has developed this Chinese Expert Consensus to guide clinical practice of CPR in COVID-19 patients.Main recommendations:1)A medical team should be assigned to evaluate severe and critical COVID-19 for early monitoring of cardiac-arrest warning signs.2)Psychological counseling and treatment are highly recommended,since sympathetic and vagal abnormalities induced by psychological stress from the COVID-19 pandemic can induce cardiac arrest.3)Healthcare workers should wear personal protective equipment(PPE).4)Mouth-to-mouth ventilation should be avoided on patients suspected of having or diagnosed with COVID-19.5)Hands-only chest compression and mechanical chest compression are recommended.6)Tracheal-intubation procedures should be optimized and tracheal-intubation strategies should be implemented early.7)CPR should be provided for 20-30 min.8)Various factors should be taken into consideration such as the interests of patients and family members,ethics,transmission risks,and laws and regulations governing infectious disease control.Changes in management:The following changes or modifications to CPR strategy in COVID-19 patients are proposed:1)Healthcare workers should wear PPE.2)Hands-only chest compression and mechanical chest compression can be implemented to reduce or avoid the spread of viruses by aerosols.3)Both the benefits to patients and the risk of infection should be considered.4)Hhealthcare workers should be fully aware of and trained in CPR strategies and procedures specifically for patients with COVID-19. | Wei Song Jie Wei Xiangdong Jian Deren Wang Yanhong Ouyang Yuanshui Liu Xianjin Du Ying Chen Yingqi Zhang Heping Xu Shuming Xianyu Qiong Ning Xiang Li Xiaotong Han Feng Zhan Tao Yu Wenteng Chen Jun Zhang Wenwei Cai Sheng’ang Zhou Shengyang Yi Yu Cao Xiaobei Chen Shunjiang Xu Zong’an Liang Duohu Wu Fen Ai Zhong Wang Qingyi Meng Yuhong Mi Sisen Zhang Rongjia Yang Shouchun Yan Wenbin Han Yong Lin Chuanyun Qian Wenwu Zhang Yan Xiong Jun Lv Baochi Liu Yan Cao Xiaojun He Xuelian Sun Yufang Cao Tian’en Zhou | 2021 | Asian Pacific Journal of Tropical Medicine2021，14，6： | 0 |
| 8 | Prospects for Russia-U.S.Relations after Putin Reassumes Presidency显示文摘The lack of a stable analytical framework is the main reason why academic circles have not been able to keep an historical and objective grasp of Russia-U.S.relations.In order to make an academic analysis of Russia-U.S.relations we must not simply rely on political statements,but we must also take into account basic variables that can affect the relationship. | Feng Yujun Feng Shengyang Zhao Jinfu | 2012 | Contemporary International Relations2012，22，4： | 0 |
| 9 | CD47KO/CRT dual-bioengineered cell membrane-coated nanovaccine combined with anti-PD-L1 antibody for boosting tumor immunotherapy显示文摘Tumor vaccines trigger tumor-specific immune responses to prevent or treat tumors by activating the hosts’immune systems,and therefore,these vaccines have potential clinical applications.However,the low immunogenicity of the tumor antigen itself and the low efficiency of the vaccine delivery system hinder the efficacy of tumor vaccines that cannot produce high-efficiency and long-lasting antitumor immune effects.Here,we constructed a nanovaccine by integrating CD47KO/CRT dual-bioengineered B16F10 cancer cell membranes and the unmethylated cytosine-phosphate-guanine(CpG)adjuvant.Hyperbranched PEI25k was used to load unmethylated cytosine-phosphate-guanine(CpG)through electrostatic adsorption to prepare PEI25k/CpG nanoparticles(PEI25k/CpG-NPs).CD47KO/CRT dual-bioengineered cells were obtained by CRISPR-Cas9 gene editing technology,followed by the cell surface translocation of calreticulin(CRT)to induce immunogenic cell death(ICD)in vitro.Finally,the extracted cell membranes were coextruded with PEI25k/CpG-NPs to construct the CD47KO/CRT dual-bioengineered cancer cell membrane-coated nanoparticles(DBE@CCNPs).DBE@CCNPs could promote endocytosis of antigens and adjuvants in murine bone marrow derived dendritic cells(BMDCs)and induce their maturation and antigen cross-presentation.To avoid immune checkpoint molecule-induced T cell dysfunction,the immune checkpoint inhibitor,the anti-PD-L1 antibody,was introduced to boost tumor immunotherapy through a combination with the DBE@CCNPs nanovaccine.This combination therapy strategy can significantly alleviate tumor growth and may open up a potential strategy for clinical tumor immunotherapy. | Shengyang Liu Jiayan Wu Yuanji Feng Xiaoya Guo Tong Li Meng Meng Jie Chen Daquan Chen Huayu Tian | 2023 | Bioactive Materials2023，，4： | 0 |
| 10 | Selective and stable Au-Cu bimetallic catalyst for CO-PROX显示文摘Gold-based catalysts are promising in CO preferential oxidation(CO-PROX)reaction in H_(2)-rich stream on account of their high intrinsic activity for CO elimination even at ambient temperature.However,the decrease of CO conversion at elevated temperature due to the competition of H_(2)oxidation,together with the low stability of gold nanoparticles,has posed a dear challenge.Herein,we report that Au-Cu bimetallic catalyst prepared by galvanic replacement method shows a wide temperature window for CO total conversion(30-100℃)and very good catalyst stability without deactivation in a 200-h test.Detailed characterizations combined with density functional theory(DFT)calculation reveal that the synergistic effect of Au-Cu,the electron transfer from Au to Cu,leads to not only strengthened chemisorption of CO but also weakened dissociation of H_(2),both of which are helpful in inhibiting the competition of H_(2)oxidation thus widening the temperature window for CO total conversion. | Feng Hong Guanjian Cheng Weihao Hu Shengyang Wang Qike Jiang Junhong Fu Botao Qiao Jiahui Huang | 2023 | Nano Research2023，16，7： | 0 |
| 11 | Research status of soil frost-heave theory and frost-heave prediction models显示文摘Soil frost heaving is a complex physical, mechanical, and chemical synthesis process. This paper summarizes the frost-heaving theory over half a century, including the capillary theory, the frozen-fringe theory, and those achievements recently made by scholars. In this paper, we also discus researching achievements of the soil-prediction model during the past 40 years, including the water-dynamics model, the rigid-ice model, the segregation-potential model, and the thermo-dynamic model. This summary and discussion will enable readers to understand the latest direction of research; it also summarizes the development of frost-heave prediction models and their advantages and shortcomings. | XiangDong Zhang ShengYang Feng | 2010 | Research in Cold and Arid Regions2010，2，1： | 0 |
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