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| 1 | Failure probability estimation of overhead transmission lines considering spatial and temporal variation in severe weather显示文摘Estimation for weather-related failure probability of overhead transmission lines is essential in the reliability assessment of a power system.This paper analyzes the outage and weather data of 110 kV overhead transmission lines in the Guangxi Zhuang Autonomous Region of China during 2011–2014.The result reveals obvious uneven distributions of outage events for time and space due to the spatial and temporal variation of severe weather.Based on the results, an estimation method is proposed in this paper.Split and aggregation is used to smooth the outage and weather data.The poisson model is adopted in our method to investigate the statistic characteristics of transmission line outage events.Regression analysis is applied to obtain the correlation between the weather intensity and history failure rate.Furthermore the method proposed is validated against the empirical outage data. | Shuai YANG Wenjun ZHOU Shiyang ZHU Le WANG Lisha YE Xuezhi XIA Han LI | 2019 | Journal of Modern Power Systems and Clean Energy2019，7，1： | 5 |
| 2 | Metasurface-based subtractive color filter fabricated on a 12-inch glass wafer using a CMOS platform显示文摘Optical color filters are widely applied in many areas including display,imaging,sensing,holography,energy harvest,and measurement.Traditional dye-based color filters have drawbacks such as environmental hazards and instability under high temperature and ultraviolet radiation.With advances in nanotechnology,structural color filters,which are based on the interaction of light with designed nanostructures,are able to overcome the drawbacks.Also,it is possible to fabricate structural color filters using standard complementary metal-oxide-semiconductor(CMOS)fabrication facilities with low cost and high volume.In this work,metasurface-based subtractive color filters(SCFs)are demonstrated on 12-inch(300-mm)glass wafers using a CMOS-compatible fabrication process.In order to make the transmissive-type SCF on a transparent glass wafer,an in-house developed layer transfer process is used to solve the glass wafer handling issue in fabrication tools.Three different heights of embedded silicon nanopillars(110,170,and 230 nm)are found to support magnetic dipole resonances.With pillar height and pitch variation,SCFs with different displayed colors are achieved.Based on the resonance wavelength,the displayed color of the metasurface is verified within the red-yellow-blue color wheel.The simulation and measurement results are compared and discussed.The work provides an alternative design for high efficiency color filters on a CMOS-compatible platform,and paves the way towards mass-producible large-area metasurfaces. | ZHENGJI XU NANXI LI YUAN DONG YUAN HSING FU TING HU QIZE ZHONG YANYAN ZHOU DONGDONG Li SHIYANG ZHU NAVAB SINGH | 2021 | Photonics Research2021，9，1： | 3 |
| 3 | CPTA treatment reveals potential transcription factors associated with carotenoid metabolism in flowers of Osmanthus fragrans显示文摘Osmanthus fragrans is one of the top ten traditional flowers in China.It is divided into three different groups according to its color.α-Carotene and β-carotene are the main determinants to distinguish the color differences between three groups.However,the dominant genes and transcription factors involved in carotenoid metabolism remain unclear.CPTA treatment(0.7mmol·L−1)remarkably promoted lycopene,α-carotene and β-carotene contents in flowers.Transcriptome sequencing analysis revealed that CPTA treatment could trigger chain reactions in carotenoid metabolism pathway genes.Four up-regulated and 10 down-regulated transcription factors which have close association with carotenoid variation were significantly induced by CPTA treatment.The up-regulated TFs such as MYB43,MYB123,HSF,were further subjected to transcript expression determination in different cultivars with drastic colors.Among them,transcript expression of four up-regulated TFs coincided with the carotenoid accumulation in different cultivars.We selected up-regulated OfMYB43 to verify its function,which is related to stress tolerance and transcriptional regulation.Transient overexpression of OfMYB43 in O.fragrans flowers showed that it could remarkably promote the expression of PDS,ZISO,LCYE and CCD4,leading to increased accumulation of β-branch carotenoids.OfMYB43 was a potential positive regulator of carotenoid biosynthesis in O.fragrans flowers.This study provides insight into the molecular mechanism of carotenoid metabolism in O.fragrans. | Wan Xi Yanhong He Linlin Zhu Shiyang Hu Shuyi Xiong Yi Zhang Jingjing Zou Hongguo Chen Caiyun Wang Riru Zheng | 2021 | Horticultural Plant Journal2021，7，5： | 3 |
| 4 | Activation of calcium-sensing receptors is associated with apoptosis in a model of simulated cardiomyocytes ischemia/reperfusion显示文摘Objective:Calcium-sensing receptors(CaSRs)are G-protein coupled receptors which maintain systemic calcium homeostasis and participate in hormone secretion,activation of ion channels,cell apoptosis,proliferation,and differentiation.Previous studies have shown that CaSRs induce apoptosis in isolated adult rat heart and in normal neonatal rat cardiomyocytes by G-protein-PLC-IP 3 signaling transduction.However,little knowledge is presently available concerning the role of CaSRs in the apoptosis induced by ischemia and reperfusion in neonatal cardiomyocytes.Methods:Primary neonatal rat ventricular cardiomyocytes were incubated in ischemiamimetic solution for 2 h,and then re-incubated in normal culture medium for 24 h to establish a model of simu- lated ischemia/reperfusion(I/R).Cardiomyocyte apoptosis was detected by terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling(TUNEL).The expression of CaSRs mRNA was detected by real-time reverse transcription polymerase chain reaction(RT-PCR).In addition,the expressions of caspase-3 and Bcl-2 were analyzed by western blot.Results:The simulated I/R enhanced the expression of CaSRs and cardiomyocyte apopto- sis.GdCl 3 ,a specific activator of CaSRs,further increased the expression of CaSRs and cardiomyocyte apoptosis, along with up-regulation of caspase-3 and down-regulation of Bcl-2.Conclusion:CaSRs are associated with I/R injury and apoptosis in neonatal rat ventricular cardiomyocytes via suppressing Bcl-2 and promoting caspase-3 expression. | Ling Yan Tlebing Zhu Tingting Sun Liansheng Wang Shiyang Pan Zhengxlan Tao Zhijian Yang Kejiang Cao | 2010 | The Journal of Biomedical Research2010，24，4： | 2 |
| 5 | Crystal growth and crystal structure of magnesium oxysulfate 2MgSO 4 ·Mg(OH) 2 ·2H 2 O显示文摘 | Yue Tao Gao Shiyang Zhu Lixia Xia Shuping Yu Kaibei | 2002 | Journal of Molecular Structure2002，，1： | 1 |
| 6 | Novel NiGe MSM photodetector featuring asymmetrical Schottky barriers using sulfur Co-implantation and segregation 显示文摘 | ANG Kah-Wee YU Mingbin ZHU Shiyang | 2008 | IEEE Electron Device Letters(S0741-3106)2008，29，7： | 1 |
| 7 | A novel liquidchip platform for simultaneous detection of 70 alleles of DNA somatic mutations on EGFR, KRAS, BRAF and PIK3CA from formalin-fixed and paraffin-embedded slides containing tumor tissue显示文摘 | Guoqiang Li Xiaodi Luo Jiaying He Zeyao Zhu Gang Yu Huijuan Qin Tao Zeng Zhiming Liu Shiyang Wu Jiasen Xu Lifen Ren-Heidenreich | 2011 | Clinical Chemistry and Laboratory Medicine2011，，2： | 1 |
| 8 | Crystal growth and crystal structure of magnesium oxysulfate 2MgSO4 · Mg(OH)2 · 2H2O显示文摘 | Yue Tao Gao Shiyang Zhu Lixia | 2002 | Journal of Molecular Structure2002，616，13： | 1 |
| 9 | Theoretical Investigation of Silicon MOS-Type Plasmonic Slot Waveguide Based MZI Modulators显示文摘 | Shiyang Zhu G. Q. Lo D. L Kwong | | 0，，26： | 1 |
| 10 | Electro-Absorption Modulation in Horizontal Metal Insulator Silicon Insulator Metal Nanoplasmonic Slot Waveguides显示文摘 | Shiyang Zhu G. Q. Lo D. L. Kwong | | 0，，15： | 1 |
| 11 | Crystal growth and crystal structure of magnesium oxysulfate 2MgSO4?Mg(OH)2?2H2O 显示文摘 | YUE Tao GAO Shiyang ZHU Lixia | 2002 | J Mol Struct2002，616，13： | 1 |
| 12 | Effects of mode coupling between low-mode radiation flux asymmetry and intermediate-mode ablator roughness on ignition capsule implosions显示文摘The low-mode shell asymmetry and high-mode hot spot mixing appear to be the main reasons for the performance degradation of the National Ignition Facility(NIF)implosion experiments.The effects of the mode coupling between low-mode P2 radiation flux asymmetry and intermediate-mode L=24 capsule roughness on the implosion performance of ignition capsule are investigated by two-dimensional radiation hydrodynamic simulations.It is shown that the amplitudes of new modes generated by the mode coupling are in good agreement with the second-order mode coupling equation during the acceleration phase.The later flow field not only shows large areal density P2 asymmetry in the main fuel,but also generates large-amplitude spikes and bubbles.In the deceleration phase,the increasing mode coupling generates more new modes,and the perturbation spectrum on the hot spot boundary is mainly from the strong mode interactions rather than the initial perturbation conditions.The combination of the low-mode and high-mode perturbations breaks up the capsule shell,resulting in a significant reduction of the hot spot temperature and implosion performance. | Jianfa Gu Zhensheng Dai Shiyang Zou Wenhua Ye Wudi Zheng Peijun Gu Shaoping Zhu | 2017 | Matter and Radiation at Extremes2017，2，1： | 1 |
| 13 | A novel mutant-enriched liquidchip technology for the qualitative detection of somatic mutations in KRAS gene from both serum and tissue samples显示文摘 | Shiyang Wu Zeyao Zhu Jiaying He Xiaodi Luo Jiasen Xu Lifen Ren-Heidenreich | 2010 | Clinical Chemistry and Laboratory Medicine2010，，： | 1 |
| 14 | Gettering of Defects in Silicon by Porous Sillicon 显示文摘 | Huang yipping Zhu shiyang Bao zongming | 1998 | Chinese Journal of Semiconductor1998，19，12： | 1 |
| 15 | Electrical characteristics of CoSiJn- Si (100) Schottky barrier contacts formed by solid state reaction 显示文摘 | Zhu Shiyang Detavernier C Van Meirhaegh R L | 2000 | Solid State Electron2000，44，： | 1 |
| 16 | Spin-orbit torque efficiency enhancement to tungsten-based SOT-MTJs by interface modification with an ultrathin MgO显示文摘Spin-orbital torque (SOT) based three-terminal magnetic tunnel junctions (MTJs) have attracted much interest as the next generation magnetic random-access memory (MRAM)key device both in the academy and the industry.This is because SOT-MTJs feature high endurance and fast switching speed,benefiting tremendously from the separation of read/write current paths and less incubation time during the write in contrast to the spin-transfer torque (STT) MTJs [1]. | Shiyang LU Xiaobai NING Hongchao ZHANG Sixi ZHEN Xiaofei FAN Danrong XIONG Dapeng ZHU Gefei WANG Hong-Xi LIU Kaihua CAO Weisheng ZHAO | 2024 | Science China(Information Sciences)2024，67，1： | 0 |
| 17 | Discovery of novel exceptionally potent and orally active c-MET PROTACs for the treatment of tumors with MET alterations显示文摘Various c-mesenchymal-to-epithelial transition(c-MET) inhibitors are effective in the treatment of non-small cell lung cancer;however, the inevitable drug resistance remains a challenge, limiting their clinical efficacy. Therefore, novel strategies targeting c-MET are urgently required. Herein, through rational structure optimization, we obtained novel exceptionally potent and orally active c-MET proteolysis targeting chimeras(PROTACs) namely D10 and D15 based on thalidomide and tepotinib. D10 and D15 inhibited cell growth with low nanomolar IC_(50) values and achieved picomolar DC_(50) values and>99% of maximum degradation(D_(max)) in EBC-1 and Hs746T cells. Mechanistically, D10 and D15dramatically induced cell apoptosis, G1 cell cycle arrest and inhibited cell migration and invasion.Notably, intraperitoneal administration of D10 and D15 significantly inhibited tumor growth in the EBC-1 xenograft model and oral administration of D15 induced approximately complete tumor suppression in the Hs746T xenograft model with well-tolerated dose-schedules. Furthermore, D10 and D15 exerted significant anti-tumor effect in cells with c-MET^(Y1230H) and c-MET^(D1228N) mutations, which are resistant to tepotinib in clinic. These findings demonstrated that D10 and D15 could serve as candidates for the treatment of tumors with MET alterations. | Pengyun Li Changkai Jia Zhiya Fan Xiaotong Hu Wenjuan Zhang Ke Liu Shiyang Sun Haoxin Guo Ning Yang Maoxiang Zhu Xiaomei Zhuang Junhai Xiao Zhibing Zheng Song Li | 2023 | Acta Pharmaceutica Sinica B2023，13，6： | 0 |
| 18 | LARGE-SCALE FARMING BENEFITS SOIL ACIDIFICATION ALLEVIATION THROUGH IMPROVED FIELD MANAGEMENT IN BANANA PLANTATIONS显示文摘Large-scale farming by agricultural land transfers has been increasingly promoted in recent years,but the possible impacts on crop production,especially cash crops,and soil acidification remain unclear.This study obtained data for 110 banana plantations in Long’an County,China,and categorized them into small(<0.67 ha),medium(0.67−6.7 ha),and large(>6.7 ha)to determine banana cultivation,nutrient management,and soil acidification rates on farms of the three sizes.Banana yield per unit area significantly increased with increased farm size,and large farms had the highest average yield(48.9 t·ha^(−1))with the least variation.Despite a significant increase in organic fertilizer and base cation inputs,nitrogen(N)surplus did not differ significantly with increasing farm size.With large farms,actual soil acidification rate was significantly lower by 19.1 to 24.0 keq·ha^(−1)·yr^(−1);however,potential soil acidification rate increased with increased overuse of phosphorus.Overall,larger banana plantations used fewer mineral N fertilizers reducing the rate of soil acidification and increasing the H+buffering provided by organic fertilizers.It is concluded that larger farms deliver the dual benefits of higher,less variable banana yield and mitigation of soil acidification by substituting organic N for mineral N fertilizers,supporting sustainable soil management and food production. | Donghao XU Jiangzhou ZHANG Yajuan LI Shiyang LI Siyang REN Yuan FENG Qichao ZHU Fusuo ZHANG | 2023 | Frontiers of Agricultural Science and Engineering2023，10，1： | 0 |
| 19 | Semi-hydro-equivalent design and performance extrapolation between 100 kJ-scale and NIF-scale indirect drive implosion显示文摘Extrapolation of implosion performance between different laser energy scales is investigated for indirect drive through a semi-hydroequivalent design.Since radiation transport is non-hydro-equivalent,the peak radiation temperature of the hohlraum and the ablation velocity of the capsule ablator are not scale-invariant when the sizes of the hohlraum and the capsule are scale-varied.A semi-hydro-equivalent design method that keeps the implosion velocity V_(i),adiabat α_(F),and P_(L)/R_(hc)^(2) (where P_(L) is the laser power and R_(hc) is the hohlraum and capsule scale length)scale-invariant,is proposed to create hydrodynamically similar implosions.The semi-hydro-equivalent design and the scaled implosion performance are investigated for the 100 kJ Laser Facility(100 kJ-scale)and the National Ignition Facility(NIF-scale)with about 2 MJ laser energy.It is found that the one-dimensional implosion performance is approximately hydro-equivalent when V_(i) and α_(F) are kept the same.Owing to the non-hydro-equivalent radiation transport,the yield-over-clean without α-particle heating(YOC_(noα))is slightly lower at 100 kJ-scale than at NIF-scale for the same scaled radiation asymmetry or the same initial perturbation of the hydrodynamic instability.The overall scaled two-dimensional implosion performance is slightly lower at 100 kJ-scale.The general Lawson criterion factor scales asχ_(noα) ^(2D)∼S^(1.06±0.04)(where S is the scale-variation factor)for the semi-hydro-equivalent implosion design with a moderate YOC_(noα).Our study indicates that χ_(noα)≈0.379 is the minimum requirement for the 100 kJ-scale implosion to demonstrate the ability to achieve marginal ignition at NIF-scale. | Huasen Zhang Dongguo Kang Changshu Wu Liang Hao Hao Shen Shiyang Zou Shaoping Zhu Yongkun Ding | 2024 | Matter and Radiation at Extremes2024，9，1： | 0 |
| 20 | Community Renewal Strategy for Improving Community Resilience:A Case Study of River Ring Area of Caoyang New Village in Shanghai显示文摘In a new round of urban renewal,China’s urban space expansion is shifting from incremental development to inventory mining.Residents’ demands for improvement of community material environment and community cultural identity are increasing.Meantime,affected by the COVID-19 pandemic in 2019,community resilience has become an urgent problem to be solved in urban communities.Based on resilience theory,TOD theory and other planning concepts,the paper analyzes the vulnerability of Shanghai Caoyang river ring area,and puts forward a multi-level community resilience improvement strategy,including increasing diversified public service facilities,building public pedestrian network,and reshaping public open space to improve the stability,adaptability and resilience of the community,in order to build the development path of resilient communities.The study will provide inspiration for future micro-renewal of communities and promote the sustainable development of urban communities. | WANG Zhenbao ZHU Lin HAO Shiyang FAN Yuting | 2021 | Journal of Landscape Research2021，13，4： | 0 |
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