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| 1 | The Inhibitory Effect of Oridonin on the Growth of Fifteen Human Cancer Cell Lines显示文摘OBJECTIVE To study the inhibitory effect of oridonin on the growth of cancer cells. METHODS Fifteen human cancer cell lines were subjected to various concentrations of oridonin in culture medium. The inhibitory rate of cell growth was measured by the MTT assay, and compared with a negative con- trol and 5-Fu-positive control. RESULTS The 50% inhibiting concentration (IC50) and maximal inhibition (Imax) of oridonin shown by studying the growth of the cancer cell lines were as follows: leukemias (HL60 cells: 3.9 μg/ml and 73.8%, K562 cells: 4.3 μg/ml and 76.2%); esophageal cancers(SHEEC cells: 15.4 μg/ml and 99.2%, Eca109 cells: 15.1 μg/ml and 84.6%, TE1 cells: 4.0 μg/ml and 70.2%); gastric cancers (BGC823 cells: 7.6 μg/ml and 98.7%, SGC7901 cells: 12.3 μg/ml and 85.7%); colon cancers (HT29 cells: 13.6 μg/ml and 97.2%, HCT cells: 14.5 μg/ml and 96.5%); liver cancers (Bel7402 cells: 15.2 μg/ml and 89.2%, HepG2 cells: 7.1 μg/ml and 88.3%); pancreatic cancer (PC3 cells: 11.3 μg/ml and 68.4%); lung cancer (A549 cells: 18.6 μg/ml and 98.0% ); breast cancer (MCF7 cells: 18.4 μg/ml and 84.7%); uterine cervix cancer (Hela cells: 13.7 μg/ml and 98.5%). CONCLUSION Oridonin had a relatively wide anti-tumor spectrum, and a relatively strong inhibitory effect on the growth of the 15 human cancer cells. Inhibitory effects were concentration dependent. | Junhui Chen Shaobin Wang Dongyang Chen Guisheng Chang Qingfeng Xin Shoujun Yuan Zhongying Shen | 2007 | Chinese Journal of Clinical Oncology2007，4，1： | 32 |
| 2 | Numerical simulation on mesoscale convective system along Mei-Yu front in Southern China显示文摘A mesoscale convective system (MCS) was generated over the South China Sea at arouna 115°E, 21°N on 0000 UTC 7 June 1998. Riding along the Mei-Yu front, the system moved through the Taiwan Strait and finally hit the southern part of the Taiwan Island, produced over 300 mm of rainfall over parts of Taiwan in the next 24 hours. It was found that the Penn State-NCAR Mesoscale Model Version 5 (MM5) did quite well in simulating the evolution of the MCS. Diagnostic studies on the mesoscale structure of MCS, moisture concentration process and the momentum budget were based on the model output. The concept model of the MCS in the mature phase can be concluded as the following: At the 850 hPa level, the mesoscale low level jet (mLLJ) was found to the southwest of the MCS, which was also associated with a mesoscale low generated by convection, the mesoscale upper level jet (mULJ) was found due east of the MCS (and an upper-level mesoscale high) at the 300 hPa level. Horizontal advection of momentum acted to | ZHANG Qinghong Kai-Hon LAU WANG Hongqing CHEN Shoujun | 2000 | Chinese Science Bulletin2000，45，22： | 11 |
| 3 | He–Ar Isotopic Tracing of Pyrite from Ore-forming Fluids of the Sanshandao Au Deposit, Jiaodong Area显示文摘The Sanshandao Au deposit is located in the famous Sanshandao metallogenic belt,Jiaodong area.To date,accumulative Au resources of 1000 t have been identified from the belt.Sanshandao is a world-class gold deposit with Au mineralization hosted in Early Cretaceous Guojialing-type granites.Thus,studies on the genesis and ore-forming element sources of the Sanshandao Au deposit are crucial.He and Ar isotopic analyses of fluid inclusions from pyrite(the carrier of Au)indicate that the fluid inclusions have 3 He/4 He=0.043–0.21 Ra with an average of 0.096 Ra and 40 Ar/36 Ar=488–664 with an average of 570.8.These values represent the initial He and Ar isotopic compositions of ore-forming fluids for trapped fluid inclusions.The comparison of H–O isotopic characteristics combined with deposit geology and wall rock alteration reveals that the ore-forming fluids of the Sanshandao Au deposit show mixed crust–mantle origin characteristics,and they mainly comprise crust-derived fluid mixed with minor mantle-derived fluid and meteoric water during the uprising process.The ore-forming elements were generally sourced from pre-Cambrian meta-basement rocks formed by Mesozoic reactivation and mixed with minor shallow crustal and mantle components. | HAN Zhenyu YU Xiaowei LI Shoujun Tian Jingxiang WANG Zhongliang YU Xiaojing WANG Ligong | 2019 | Acta Geologica Sinica(English Edition)2019，93，6： | 5 |
| 4 | Seismic performance evaluation of an infilled rocking wall frame structure through quasi-static cyclic testing显示文摘Earthquake investigations have illustrated that even code-compliant reinforced concrete frames may suffer from soft-story mechanism.This damage mode results in poor ductility and limited energy dissipation.Continuous components offer alternatives that may avoid such failures.A novel infilled rocking wall frame system is proposed that takes advantage of continuous component and rocking characteristics.Previous studies have investigated similar systems that combine a reinforced concrete frame and a wall with rocking behavior used.However,a large-scale experimental study of a reinforced concrete frame combined with a rocking wall has not been reported.In this study,a seismic performance evaluation of the newly proposed infilled rocking wall frame structure was conducted through quasi-static cyclic testing.Critical joints were designed and verified.Numerical models were established and calibrated to estimate frame shear forces.The results evaluation demonstrate that an infilled rocking wall frame can effectively avoid soft-story mechanisms.Capacity and initial stiffness are greatly improved and self-centering behavior is achieved with the help of the infilled rocking wall.Drift distribution becomes more uniform with height.Concrete cracks and damage occurs in desired areas.The infilled rocking wall frame offers a promising approach to achieving seismic resilience. | Pan Peng Wu Shoujun Wang Haishen Nie Xin | 2018 | Earthquake Engineering and Engineering Vibration2018，17，2： | 5 |
| 5 | New approach to the automatic segmentation of coronary artery in X-ray angiograms显示文摘For the segmentation of X-ray angiograms (XRA), the essential feature and the prior knowledge of angiographic image were analyzed, and a multi-feature based fuzzy recognition (MFFR) algorithm was proposed to infer the local vessel structure in this paper. Guided by the prior knowledge of artery vessel, a probability tracking operator (PTO) can rapidly track along the artery tree, and walk across the weak region or gaps because of disturbance or preprocessing to angiographic image. Another, the accurate measurement of the vascular axis-lines and diameters can be synchronously implemented in the tracking process. To correctly evaluate the proposed method, a simulated image of CAT and some clinical XRA images were used in the experimentations. The algorithms performed better than the conven- tional one: given one start-point, on average 92.7% of the visible segments or branches was automatically delineated; the correctness ratio of vessel structure inference reached to 90.0% on the average. | ZHOU ShouJun YANG Jun CHEN WuFan WANG YongTian | 2008 | Science in China(Series F)2008，51，1： | 3 |
| 6 | Blue revolution for food security under carbon neutrality: A case from the water-saving and drought-resistance rice显示文摘The increasing concentration of greenhouse gases(GHGs)in Earth's atmosphere leads to global warming,which further causes a series of climate changes and does great harm to both human society and natural ecosystems.Agricultural GHG emissions,mainly in theform of methane(CH4)and nitrous oxide(N2O),areasignificantsourceofGHGs,accountingfor~14%total global GHGs(Zhang et al.,2022).One major source of agricultural GHGs is CH4 emissions from rice paddies,which is responsiblefor~10%-12%ofhuman-inducedCH4emissions(van Groenigen et al.,2013)and contributes~2.40%to the enhanced global warming effect(Zhang et al.,2022).The global warming potential of GHGs emissions from rice systems is roughly four times higher than either wheat or maize(Linquist et al.,2012). | Hui Xia Xianxian Zhang Yi Liu Junguo Bi Xiaosong Ma Anning Zhang Hongyan Liu Liang Chen Sheng Zhou Huan Gao Kai Xu Haibin Wei Guolan Liu Feiming Wang Hongyang Zhao Xingxing Luo Danping Hou Qiaojun Lou Fangjun Feng Liguo Zhou Shoujun Chen Ming Yan Tianfei Li Mingshou Li LeiWang Zaochang Liu Xinqiao Yu HanweiMei Lijun Luo | 2022 | Molecular Plant2022，15，9： | 3 |
| 7 | A review on nitrogen transformation and conversion during coal pyrolysis and combustion based on quantum chemical calculation and experimental study显示文摘The emission of NOx during coal combustion contributes to the formation of acid rain and photochemical smog,which would seriously affect the quality of atmospheric environment.Therefore,the decrease of NOx is of great importance for improving the efficient utilization of coal.The present review comprehensively summarized the influence factors and mechanisms of migration and transformation of nitrogen during the coal pyrolysis and combustion based on experimental study and quantum chemical calculation.Firstly,in the process of pyrolysis:the occurrence state and transformation of nitrogen were concluded.The influence of temperature,atmosphere,heating rate and catalyst on formation of NOx precursor and nitrogen migration path at the molecular level were summarized;Secondly,during the process of combustion:the influence of temperature,ambient oxygen concentration,physical structure of coal char,catalyst on heterogeneous oxidation of char(N)were summarized;The effects of char surface properties,catalyst and ambient atmosphere on heterogeneous reduction of NOx were also concluded.Based on the quantum chemical calculation,the reaction path of heterogeneous oxidation of char-N and heterogeneous reduction of NOx were described in detail.Current studies focus more on the generation of HCN and NH3,but in order to reduce the pollution of NOx from the source,it is necessary to further improve the process conditions and the optimal formula of producing more N2 during pyrolysis,as well as clarify the path of the generation of N2.Experiments study and quantum chemistry calculation should be combined to complete the research of directional nitrogen reduction during pyrolysis and denitration during combustion. | Tingting Jiao Huiling Fan Shoujun Liu Song Yang Wenguang Du Pengzheng Shi Chao Yang Yeshuang Wang Ju Shangguan | 2021 | Chinese Journal of Chemical Engineering2021，34，7： | 2 |
| 8 | Nonvolatile reconfigurable dynamic Janus metasurfaces in the terahertz regime显示文摘Metasurfaces,especially tunable ones,have played a major role in controlling the amplitude,phase,and polarization of electromagnetic waves and attracted growing interest,with a view toward a new generation of miniaturized devices.However,to date,most existing reconfigurable devices are bounded in volatile nature with sustained external energy to maintain and single functionality,which restrict their further applications.Here,we demonstrate for the first time,to our knowledge,nonvolatile,reconfigurable,and dynamic Janus metasurfaces by incorporating phase-change material Ge_(2)Se_(2)Te_(5)(GST)in the terahertz(THz)regime.First,we experimentally show the reversible switching characteristic of GST on large areas by applying a single nanosecond laser pulse,which exhibits excellent contrast of THz properties in both states.Then,we present a multiplex metasurface scheme.In each metasurface,three sets of structures are adopted,in which two sets integrate GST.The effective structures can be reversely modulated by the amorphization and crystallization of GST.As a proof of concept,the dynamic beam splitter,bifocal metalens,dual-mode focusing optical vortex generators,and switchable metalens/focusing optical vortex generators are designed,fabricated,and experimentally characterized,and can be switched reversibly and repeatedly with the help of optical and thermal stimuli.Our scheme will pave the way toward the development of multifunctional and compact THz devices and may find use for applications in THz imaging,sensing,and communications. | SHOUJUN ZHANG XIEYU CHEN KUAN LIU HAIYANG LI YUEHONG XU XIAOHAN JIANG YIHAN XU QINGWEI WANG TUN CAO ZHEN TIAN | 2022 | Photonics Research2022，10，7： | 2 |
| 9 | Import of Rift Valley fever to China:a potential new threat?显示文摘Several recent studies in Virologica Sinica and other journals have highlighted the enormous international challenge of emerging arboviral diseases,such as Zika virus disease,dengue,and chikungunya(Islam et al.,2015;Maurice et al.,2015;Dai et al.,2016;Deng et al.,2016;Song et al.,2016;Wang et al.,2016;Xu et al.,2016;Zhang et al.,2016;Zhou | Xinliang FU Lifang Wang Bo Fang Ruirui Ma Yun Zheng San Huang Pei Zhou Zongxi Cao Jin Tian Shoujun Li Guihong Zhang | 2016 | Virologica Sinica2016，31，5： | 2 |
| 10 | H5N6禽流感病毒的基因起源、进化和流行显示文摘2014~2016年间对我国16个省份活禽市场的监测,共鉴定了3174份流感阳性样品,分离并测序了1135份禽流感病毒,分属于31种亚型。 | yuhai bi quanjiao chen qianli wang jianjun chen tao jin gary wong chuansong quan jun liu jun wu renfu yin lihua zhao mingxin li zhuang ding rongrong zou wen xu hong li huijun wang kegong tian guanghua fu yu huang alexander shestopalov shoujun li bing xu hongjie yu tingrong luo lin lu xun xu yang luo 刘映霞 史卫峰 刘翟 高福 | 2017 | 科学新闻2017，0，4： | 2 |
| 11 | Reconfigurable and nonvolatile terahertz lithography-free photonic devices based on phase change films显示文摘High-performance terahertz(THz)devices with reconfigurable features are highly desirable in many promising THz applications.However,most of the existing reconfigurable THz elements are still limited to volatile responses,single functionality,and time-consuming multistep manufacturing procedures.In this paper,we report a lithography-free approach to create reconfigurable and nonvolatile THz components by exploring the reversible,nonvolatile,and continuous THz modulation capability of the phase change material Ge_(2)Sb_(2)Te_(5).As a proof of concept,THz gratings with significant Rayleigh anomalies and diffraction as well as ultrathin THz flat lenses with subwavelength and ultra-broadband focusing capabilities are designed and fabricated on ultrathin Ge_(2)Sb_(2)Te_(5)films using the presented photo-imprint strategy.Moreover,such a method can also be adopted to create more complex THz devices,such as Pancharatnam–Berry phase metasurfaces and grayscale holographic plates.With these findings,the proposed method will provide a promising solution to realize reconfigurable and nonvolatile THz elements. | XIEYU CHEN SHOUJUN ZHANG KUAN LIU YUEHONG XU XIAOHAN JIANG HAIYANG LI XI FENG QINGWEI WANG YONGCHANG LU KEMENG WANG TUN CAO ZHEN TIAN | 2023 | Photonics Research2023，11，4： | 1 |
| 12 | Modelling loop-top X-ray source and reconnection outflows in solar flares with intense lasers显示文摘 | Zhong Jiayong Li Yutong Wang Xiaogang Wang Jiaqi Dong Quanli Xiao Chijie Wang Shoujun Liu Xun Zhang Lei An Lin Wang Feilu Zhu Jianqiang Gu Yuan He Xiantu Zhao Gang Zhang Jie | 2010 | Nature Physics2010，，12： | 1 |
| 13 | Impact of roxarsone on the UASB reactor performance and its degradation显示文摘 | Mengchuan Shui Feng Ji Rui Tang Shoujun Yuan Xinmin Zhan Wei Wang Zhenhu Hu | 2016 | Frontiers of Environmental Science & Engineering2016，10，6： | 1 |
| 14 | Ulinastatin as a neuroprotective and anti‐inflammatory agent in infant piglets model undergoing surgery on hypothermic low‐flow cardiopulmonary bypass显示文摘 | Xiaocou Wang Qinghua Xue Fuxia Yan Lihuan Li Jinping Liu Shoujun Li Shengshou Hu | 2013 | Paediatr Anaesth2013，，3： | 1 |
| 15 | Modelling loop-top X-ray source and reconnection outflows in solar flares with intense lasers显示文摘 | Zhong Jiayong Li Yutong Wang Xiaogang Wang Jiaqi Dong Quanli Xiao Chijie Wang Shoujun Liu Xun Zhang Lei An Lin Wang Feilu Zhu Jianqiang Gu Yuan He Xiantu Zhao Gang Zhang Jie | 2010 | Nature Physics2010，，12： | 1 |
| 16 | 显示文摘 | Ma Yaqi Zhao Li Wang Shoujun | 2007 | Journal of Harbin Uni versity of Commerce: Natural Sciences Edition2007，23，4： | 1 |
| 17 | Highly Photoluminescent Carbon Dots for Multicolor Patterning, Sensors, and Bioimaging显示文摘 | Shoujun Zhu Qingnan Meng Lei Wang Junhu Zhang Yubin Song Han Jin Kai Zhang Hongchen Sun Haiyu Wang Bai Yang | 2013 | Angew. Chem. Int. Ed2013，，14： | 1 |
| 18 | RETRACTED ARTICLE:Thermal,mechanical,and tribological properties of sodium-montmorillonite-nanoparticle-reinforced polyethersulfone and polytetrafluoroethylene ternary composites显示文摘The Editor-in-Chief has retracted this article[1]because a large number of figures as well significant parts of the text overlap with the 2017 Ph.D.thesis by Zhen Zuo[2].All authors agree to this retraction.[1]Yan S C,Xue Y H,Hu Y H,Wang S J.Thermal,mechanical,and tribological properties of sodium-montmorillonite-nanoparticlereinforced polyethersulfone and polytetrafluoroethylene ternary composites.Friction(2020).http://gffzzd3cc09b8251d45dfsucpcv9k6qxx06x9p.ffgz.tsg.suse.edu.cn/10.1007/s40544-019-0343-x.[2]Zuo Z.Research on tribological property and friction interface interaction of PES/PTFE composite.Ph.D Thesis.Qinhuangdao(China):Yanshan University,2017. | Shicheng YAN Yahong XUE Yahui HU Shoujun WANG | 2022 | Friction2022，10，7： | 1 |
| 19 | Ionic liquids in transdermal drug delivery system: Current applications and future perspectives显示文摘The transdermal drug delivery(TDD) shows considerable advantages over other administration pathways.However, conventional enhancing permeation methods face a series of challenges owing to barrier function provided by the skin, of which enhancing abilities either are so strong that it results in toxicity and irritation, or too weak to achieve desirable therapeutical effects. To address these issues, it is an urgent need to develop a novel method to overcome the limitations of current measures. Fortunately, in the preceding decades, ionic liquids(ILs) have been extensively studied and increasingly applied in pharmaceutical drug delivery due to their unique physicochemical and biological properties. What is more, tunability of structure resolves the challenges in processing active pharmaceutical ingredient(API) formulation, such as polymorphism and poor solubility of drugs. Thus, the presence of ILs provides an ample design space for the transdermal drug delivery system(TDDS). This review discusses the shortcomings of conventional enhancing permeation methods and introduces the application of ILs in transdermal delivery from three aspects: i) ILs are applied as enhancers to weaken the barrier function of the stratum corneum(SC). ii) As counterions, ILs are combined with API to modify the physicochemical properties of drugs. iii) ILs assist in the design of transdermal preparation for perfecting formulation. This review comprehensively introduces the major breakthroughs made in the applications of ILs, which can serve as guidance to provide novel ideas for formulation scientists who hit the bottleneck in the development of TDD. | Yang Zhang Chao Liu Jiaqi Wang Shoujun Ren Yilin Song Peng Quan Liang Fang | 2023 | Chinese Chemical Letters2023，34，3： | 1 |
| 20 | Highly Photoluminescent Carbon Dots for Multicolor Patterning, Sensors, and Bioimaging显示文摘 | Shoujun Zhu Qingnan Meng Lei Wang Junhu Zhang Yubin Song Han Jin Kai Zhang Hongchen Sun Haiyu Wang Bai Yang | 2013 | Angew Chem Int Ed2013，，14： | 1 |
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