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| 1 | A dynamic N^6-methyladenosine methylome regulates intrinsic and acquired resistance to tyrosine kinase inhibitors显示文摘 | Fei Yan Aref AI-Kali Zijie Zhang Jun Liu Jiuxia Pang Na Zhao Chuan He Mark R. Litzow Shujun Liu | 2018 | Cell Research2018，28，11： | 15 |
| 2 | Biofunctional magnesium coated Ti6Al4V scaffold enhances osteogenesis and angiogenesis in vitro and in vivo for orthopedic application显示文摘The insufficient osteogenesis and osseointegration of porous titanium based scaffold limit its further application.Early angiogenesis is important for scaffold survival.It is necessary to develop a multifunctional surface on titanium scaffold with both osteogenic and angiogenic properties.In this study,a biofunctional magnesium coating is deposited on porous Ti6Al4V scaffold.For osseointegration and osteogenesis analysis,in vitro studies reveal that magnesium-coated Ti6Al4V co-culture with MC3T3-E1 cells can improve cell proliferation,adhesion,extracellular matrix(ECM)mineralization and ALP activity compared with bare Ti6Al4V cocultivation.Additionally,MC3T3-E1 cells cultured with magnesium-coated Ti6Al4V show significantly higher osteogenesisrelated genes expression.In vivo studies including fluorochrome labeling,micro-computerized tomography and histological examination of magnesium-coated Ti6Al4V scaffold reveal that new bone regeneration is significantly increased in rabbits after implantation.For angiogenesis studies,magnesium-coated Ti6Al4V improve HUVECs proliferation,adhesion,tube formation,wound-healing and Transwell abilities.HUVECs cultured with magnesium-coated Ti6Al4V display significantly higher angiogenesis-related genes(HIF-1αand VEGF)expression.Microangiography analysis reveal that magnesium-coated Ti6Al4V scaffold can significantly enhance the blood vessel formation.This study enlarges the application scope of magnesium and provides an optional choice to the conventional porous Ti6Al4V scaffold with enhanced osteogenesis and angiogenesis for further orthopedic applications. | Peng Gao Bo Fan Xiaoming Yu Wenwen Liu Jie Wu Lei Shi Di Yang Lili Tan Peng Wan Yulin Hao Shujun Li Wentao Hou Ke Yang Xiaokang Li Zheng Guo | 2020 | Bioactive Materials2020，5，3： | 15 |
| 3 | Electron Beam Melted Beta-type Ti–24Nb–4Zr–8Sn Porous Structures With High Strength-to-Modulus Ratio显示文摘Electron beam melting(EBM)has been used to manufactureβ-type Ti–24Nb–4Zr–8Sn porous components with 70%porosity.EBM-produced components have favorable structural features(i.e.smooth strut surfaces,fewer defects)and an(α+β)-type microstructure,similar to that subjected to aging treatment.EBM-produced components exhibit more than twice the strength-to-modulus ratio of porous Ti–6Al–4V components having the same porosity.The processing–microstructure–property relationship and deformation behavior of EBM-produced components are discussed in detail.Such porous titanium components composed of non-toxic elements and having high strength-to-modulus ratio are highly attractive for biomedical applications. | Yujing Liu Shujun Li Wentao Hou Shaogang Wang Yulin Hao Rui Yang Timothy B.Sercombe Lai-Chang Zhang | 2016 | Journal of Materials Science & Technology2016，32，6： | 9 |
| 4 | Secretory/releasing proteome-based identification of plasma biomarkers in HBV-associated hepatocellular carcinoma显示文摘For successful therapy, hepatocellular carcinoma (HCC) must be detected at an early stage. Herein, we used a proteomic approach to analyze the secretory/releasing proteome of HCC tissues to identify plasma biomarkers. Serum-free conditioned media (CM) were collected from primary cultures of cancerous tissues and surrounding noncancerous tissues. Proteomic analysis of the CM proteins permitted the identification of 1365 proteins. The enriched molecular functions and biological processes of the CM proteins, such as hydrolase activity and catabolic processes, were consistent with the liver being the most important metabolic organ. Moreover, 19% of the proteins were characterized as extracellular or membrane-bound. For validation, secretory proteins involved in transforming growth factor-β signaling pathways were validated in plasma samples. Alphafetoprotein (AFP), metalloproteinase (MMP)1, osteopontin (OPN), and pregnancy-specific beta-1-glycoprotein (PSG)9 were significantly increased in HCC patients. The overall performance of MMP1 and OPN in the diagnosis of HCC remained greater than that of AFP. In addition, this study represents the first report of MMP1 as a biomarker with a higher sensitivity and specificity than AFP. Thus, this study provides a valuable resource of the HCC secretome with the potential to investigate serological biomarkers. MMP1 and OPN could be used as novel biomarkers for the early detection of HCC and to improve the sensitivity of biomarkers compared with AFP. | YANG Lei RONG WeiQi XIAO Ting ZHANG Ying XU Bin LIU Yu WANG LiMing WU Fan QI Jun ZHAO XiuYing WANG HongXia HAN NaiJun GUO SuPing WU JianXiong GAO YanNing CHENG ShuJun | 2013 | Science China(Life Sciences)2013，56，7： | 9 |
| 5 | Two-fluid modeling of Geldart A particles in gas-solid micro-fluidized beds显示文摘The fluidizadon behavior of Geldart A particles in a gas-solid micro-fluidized bed was investigated by Eulerian-Eulerian numerical simulation.The commonly used Gidaspow drag model was tested first.The simulation showed that the predicted minimum bubbling velocities were significantly lower than the experimental data even when an extremely fine grid size(of approximately one particle diameter) was used.The modified Gibilaro drag model was therefore tested next.The predicted minimum bubbling velocity and bed voidage were in reasonable agreement with the experimental data available in literature.The experimentally observed regime transition phenomena from bubbling to slugging were also reproduced successfully in the simulations.Parametric studies indicated that the solid-wall boundary conditions had a significant impact on the predicted gas and solid flow behavior. | Xiaoxing Liu Chuanqiang Zhu Shujun Geng Meiqin Yao Jinhui Zhan Guangwen Xu | 2015 | Particuology2015，13，4： | 8 |
| 6 | (Bi_(0.51)Na_(0.47))TiO_(3) based lead free ceramics with high energy density and efficiency显示文摘Dielectric ceramics with high energy storage density and energy efficiency play an important role in high power energy storage applications.In this work,lead free relaxor ferroelectric ceramics in (1-x) Bi_(0.51)Na_(0.47)TiO_(3-x)Ba(Zr_(0.3)Ti_(0.7))O_(3)(BNT-BZT100x:x=0.20,0.30,0.40 and 0.50)system are fabricated by conventional solid-state sintering method.The BNT-BZT100x ceramics are sintered dense with minimal pores,exhibiting pseudocubic symmetry and strong relaxor characteristic.A high energy storage density of 3.1 J/cm^(3) and high energy efficiency of 91% are simultaneously achieved in BNT-BZT40 ceramic with 0.1mm in thickness,at the applied electric field of 280 kV/cm.The temperature stability of the energy density is studied over temperature range of 20-160℃ ,showing minimal variation below 1.5%,together with the excellent cycling reliability(the variations of both energy density and efficiency are below 3% up to 106 cycles),making BNT-BZT40 ceramic promising candidate for high-temperature dielectric and energy storage applications. | Yu Huang Fei Li Hua Hao Fangquan Xia Hanxing Liu Shujun Zhang | 2019 | Journal of Materiomics2019，5，3： | 7 |
| 7 | Pose Planning for the End-effector of Robot in the Welding of Intersecting Pipes显示文摘All-position robots are widely applied in the welding of complicated parts.Welding of intersecting pipes is one of the most typical tasks.The welding seam is a complicated saddle-like space curve,which puts a great challenge to the pose planning of end-effector.The special robots designed specifically for this kind of tasks are rare in China and lack sufficient theoretical research.In this paper,a systematic research on the pose planning for the end-effectors of robot in the welding of intersecting pipes is conducted. First,the intersecting curve of pipes is mathematically analyzed.The mathematical model of the most general intersecting curve of pipes is derived,and several special forms of this model in degraded situations are also discussed.A new pose planning approach of bisecting angle in main normal plane(BAMNP) for the welding-gun is proposed by using differential geometry and the comparison with the traditional bisecting angle in axial rotation plane(BAARP) method is also analytically conducted.The optimal pose of the welding-gun is to make the orientation posed at the center of the small space formed by the two cylinders and the intersecting curve to help the welding-pool run smoothly.The BAMNP method can make sure the pose vertical to the curve and center between the two cylinders at the same time,therefore its performance in welding-technique is superior to the BAARP method.By using the traditional BAARP method,the robot structure can become simpler and easier to be controlled,because one degree of freedom(DOF) of the robot can be reduced.For the special case of perpendicular intersecting,an index is constructed to evaluate the quality of welding technique in the process of welding.The effect of different combination of pipe size on this index is also discussed.On the basis of practical consideration,selection principle for BAARP and BAMNP is described.The simulations of those two methods for a serial joint-type robot are made in MATLAB,and the simulation results are consistent to the analysis.The mathematical model and the proposed new pose-planning method will lay a solid foundation for future researches on the control and design of all-position welding robots. | LIU Yu ZHAO Jing LU Zhenyang CHEN Shujun | 2011 | Chinese Journal of Mechanical Engineering2011，24，2： | 7 |
| 8 | Discrete and continuum modeling of granular flow in silo discharge显示文摘 | Tian Tian Jinglin Su Jinhui Zhan Shujun Geng Guangwen Xu Xiaoxing Liu | 2018 | Particuology2018，16，1： | 6 |
| 9 | Pertuzumab in combination with trastuzumab and chemotherapy for Chinese patients with HER2-positive metastatic gastric or gastroesophageal junction cancer:a subpopulation analysis of the JACOB trial显示文摘Background:The JACOB trial(NCT01774786)was a double-blinded,placebo-controlled,randomized,multicenter,international,phase III trial evaluating the efficacy and safety of adding pertuzumab to trastuzumab and chemo-therapy in first-line treatment of human epidermal growth factor receptor 2(HER2)-positive metastatic gastric cancer/gastroesophageal junction cancer(GEJC).The aim of this analysis was to investigate efficacy and safety outcomes in the Chinese subpopulation from the JACOB trial.Methods:This post hoc subpopulation analysis included all patients recruited in China's Mainland(n=163;20.9%)between June 2013 and January 2016.The patients were randomly assigned in a 1:1 ratio to receive pertuzumab plus trastuzumab and chemotherapy(pertuzumab group;n=82)or placebo plus trastuzumab and chemotherapy(con-trol group;n=81).Intravenous pertuzumab(840 mg)and trastuzumab(8 mg/kg loading and 6 mg/kg maintenance doses)were given every 3 weeks until disease progression or unacceptable toxicity.Chemotherapy was given as per standard regimens/doses of capecitabine or 5-fluorouracil plus cisplatin.The primary endpoint was overall survival(OS);secondary efficacy endpoints included progression-free survival(PFS),and overall objective response rate(ORR).Results:The median OS was 18.7 months in the pertuzumab group and 16.1 months in the control group(hazard ratio[HR]0.75;95%confidence interval[CI]0.49 to 1.14).The median PFS was 10.5 and 8.6 months in the pertuzumab and control groups,respectively(HR 0.85;95%CI 0.60 to 1.21),and the median ORRs were 68.9%and 55.7%,respectively.The treatment effect in this Chinese subpopulation showed consistency with that in the global ITT population with numerically lower HR for OS and PFS compared with the control group.The safety profiles of the pertuzumab and control groups in this Chinese subpopulation analysis were generally comparable.The most common grade 3-5adverse events were neutropenia,anemia,and leukopenia.However,due to the nature of being a post hoc subgroup analysis,the results presented here are descriptive only and need to be interpreted with caution.Conclusions:OS and PFS were numerically improved by adding pertuzumab to trastuzumab and chemotherapy as first-line treatment in Chinese HER2-positive gastric cancer/GEJC patients,and this regimen demonstrated an acceptable safety profile. | Tianshu Liu Yanru Qin Jin Li Ruihua Xu Jianming Xu Shujun Yang Shukui Qin Yuxian Bai Changping Wu Yixiang Mao Haiyan Wu Yilin Ge Lin Shen | 2019 | Cancer Communications2019，39，1： | 6 |
| 10 | Analysis of severe human adenovirus infection outbreak in Guangdong Province,southern China in 2019显示文摘During 2018–2019,a severe human adenovirus(HAdV)infection outbreak occurred in southern China.Here,we screened 18 respiratory pathogens in 1704 children(≤14 years old)hospitalized with acute respiratory illness in Guangzhou,China,in 2019.In total,151 patients had positive HAdV test results;34.4%(52/151)of them exhibited severe illness.HAdV infection occurred throughout the year,with a peak in summer.The median patient age was 3.0(interquartile range:1.1–5.0)years.Patients with severe HAdV infection exhibited increases in12 clinical indexes(P≤0.019)and decreases in four indexes(P≤0.007),compared with patients exhibiting nonsevere infection.No significant differences were found in age or sex distribution according to HAdV infection severity(P>0.05);however,the distributions of comorbid disease and HAdV co-infection differed according to HAdV infection severity(P<0.05).The main epidemic types were HAdV-3(47.0%,71/151)and HAdV-7(46.4%,70/151).However,the severe illness rate was significantly higher in patients with HAdV-7(51.4%)than in patients with HAdV-3(19.7%)and other types of HAdV(20%)(P<0.001).Sequencing analysis of genomes/capsid genes of 13 HAdV-7 isolates revealed high similarity to previous Chinese isolates.A representative HAdV-7isolate exhibited a similar proliferation curve to the curve described for the epidemic HAdV-3 strain Guangzhou01(accession no.DQ099432)(P>0.05);the HAdV-7 isolate exhibited stronger virulence and infectivity,compared with HAdV-3(P<0.001).Overall,comorbid disease,HAdV co-infection,and high virulence and infectivity of HAdV-7 were critical risk factors for severe HAdV infection;these data can facilitate treatment,control,and prevention of HAdV infection. | Wenkuan Liu Shuyan Qiu Li Zhang Hongkai Wu Xingui Tian Xiao Li Duo Xu Jing Dai Shujun Gu Qian Liu Dehui Chen Rong Zhou | 2022 | Virologica Sinica2022，37，3： | 5 |
| 11 | Abnormal Metabolic Connectivity in Rats at the Acute Stage of Ischemic Stroke显示文摘Stroke at the acute stage is a major cause of disability in adults, and is associated with dysfunction of brain networks. However, the mechanisms underlying changes in brain connectivity in stroke are far from fully elucidated. In the present study, we investigated brain metabolism and metabolic connectivity in a rat ischemic stroke model of middle cerebral artery occlusion(MCAO)at the acute stage using18 F-fluorodeoxyglucose positron emission tomography. Voxel-wise analysis showed decreased metabolism mainly in the ipsilesional hemisphere, and increased metabolism mainly in the contralesional cerebellum. We used further metabolic connectivity analysis to explore the brain metabolic network in MCAO.Compared to sham controls, rats with MCAO showed most significantly reduced nodal and local efficiency in the ipsilesional striatum. In addition, the MCAO group showed decreased metabolic central connection of the ipsilesional striatum with the ipsilesional cerebellum, ipsilesional hippocampus, and bilateral hypothalamus. Taken together,the present study demonstrated abnormal metabolic connectivity in rats at the acute stage of ischemic stroke, which might provide insight into clinical research. | Shengxiang Liang Xiaofeng Jiang Qingqing Zhang Shaofeng Duan Tianhao Zhang Qi Huang Xi Sun Hua Liu Jie Dong Weilin Liu Jing Tao Shujun Zhao Binbin Nie Lidian Chens Baoci Shan | 2018 | Neuroscience Bulletin2018，34，5： | 5 |
| 12 | A comparative study of hydrothermal aging effect on cerium and lanthanum doped Cu/SSZ-13 catalysts for NH_(3)-SCR显示文摘Ce-or La-doped Cu/SSZ-13 catalysts were prepared by a hydrothermal method and Cu,Ce or La ions were incorporated through stepwise ion exchange,The catalyst activity was measured for the ammonia selective catalytic reduction reaction.The structure and composition of catalyst were characterized by using X-ray diffraction,scanning electron microscopy,inductively coupled plasma mass spectrometry solid-state NMR,NH_(3)-TPD techniques,and the active components were examined by XPS and XANES.The results indicate that the Ce and La doping can both completely preserve the SCR activity of Cu/SSZ-13 above 300℃,but there is also a decrease of activity below 200℃.On the other hand,Ce doping is beneficial to the formation of framework aluminum,stabilizes molecular sieve framework and Cu active sites of Cu/SSZ-13,thereby improves the catalyst hydrothermal stability.But La doping will decrease the amount of framework aluminum and Cu active sites of Cu/SSZ-13 after hydrothermally aging,even destroy zeolite CHA structure.This is quite harmful to the catalyst hydrothermal stability. | Di Deng Shujun Deng Dandan He Zhiheng Wang Zhipeng Chen Yi Ji Guoping Yan Guangjin Hou Licheng Liu Hong He | 2021 | Journal of Rare Earths2021，39，8： | 5 |
| 13 | Evolution Toward Artificial Intelligence of Things Under 6G Ubiquitous⁃X显示文摘With the evolution of cellular networks,6G is a promising technology to provide ubiquity of communications,computing,control,and consciousness(UC4)for“human⁃machine⁃thing⁃genie”and build a ubiquitous intelligent mobile society.Genie,which can act as the artificial intelligence assistance for 6G users,is the key enabler to realize the unprecedented transformation from mobile Internet to network of intelligence.While Internet of Things(IoT)is the digital nervous system,genie acts like the brain of the overall system.Supported by 6G,IoT will step into the Artificial Intelligence of Things(AIoT)era and the AIoT networks have the abilities of intelligent perception,intelligent analysis,and intelligent control.In this paper,the concept of Ubiquitous⁃X is introduced,which is considered as the fundamental architecture of 6G network,and the definition and architecture of AIoT under Ubiquitous⁃X is also presented.Several major technical challenges posed by the service requirements of novel AIoT applications are pinpointed,including massive and intelligent connectivity,efficient computing,security,privacy,authentication,high scalability and efficiency.Potential enabling technologies to support seamless service experiences across terminals to realize AIoT are introduced as well. | Ping Zhang Xiaodong Xu Xiaoqi Qin Yiming Liu Nan Ma Shujun Han | 2020 | Journal of Harbin Institute of Technology(New Series)2020，27，3： | 4 |
| 14 | Implantable nerve guidance conduits:Material combinations,multi-functional strategies and advanced engineering innovations显示文摘Nerve guidance conduits(NGCs)have attracted much attention due to their great necessity and applicability in clinical use for the peripheral nerve repair.Great efforts in recent years have been devoted to the development of high-performance NGCs using various materials and strategies.The present review provides a comprehensive overview of progress in the material innovation,structural design,advanced engineering technologies and multi functionalization of state-of-the-art nerve guidance conduits NGCs.Abundant advanced engineering technologies including extrusion-based system,laser-based system,and novel textile forming techniques in terms of weaving,knitting,braiding,and electrospinning techniques were also analyzed in detail.Findings arising from this review indicate that the structural mimetic NGCs combined with natural and synthetic materials using advanced manufacturing technologies can make full use of their complementary advantages,acquiring better biomechanical properties,chemical stability and biocompatibility.Finally,the existing challenges and future opportunities of NGCs were put forward aiming for further research and applications of NGCs. | Yixin Yan Ruotong Yao Jingyuan Zhao Kaili Chen Lirong Duan Tian Wang Shujun Zhang Jinping Guan Zhaozhu Zheng Xiaoqin Wang Zekun Liu Yi Li Gang Li | 2022 | Bioactive Materials2022，7，5： | 4 |
| 15 | Preheating Combustion Characteristics of Ultra-Low Volatile Carbon-Based Fuel显示文摘Pulverized coal combustion technology with preheating solid fuel in a circulating fluidized bed was used for the combustion test of ultra-low volatile carbon-based fuel.This paper first validated the feasibility and advantages of applying the combustion technology to this kind of fuel.The carbon-based fuel could achieve a stable preheating process in this test system.After the preheating,the apparent sensible heat of the fuel was significantly increased.This provided a necessary condition for the stable ignition and efficient combustion of the carbon-based fuel in the post-combustion chamber.The relative proportions of CO,H2,and CH4 in preheated coal gas were very low,and the effect of high-temperature coal gas at the entrance of the post-combustion chamber was greatly impaired,indicating that the combustion process in post-combustion chamber was mainly the combustion of preheated char.At the same time,the strong reducing atmosphere in the circulating fluidized bed also facilitated the reduction of fuel-nitrogen into N2,which resulted in low NOx emissions.On this basis,with the combination of preheating combustion technology and air-staging combustion technology,the NOx emissions had drastically decreased when the burnout air distribution position moved down or varied from a single-layer distribution to a multi-layer distribution system.The lowest original NOx emissions were 90.6 mg/m3(at 6%O2),and the combustion efficiency exceeded 97%,which ultimately achieved efficient and clean combustion of ultra-low volatile carbon-based fuel. | ZHU Shujun LYU Qinggang ZHU Jianguo LI Jiarong MAN Chengbo LIU Wen | 2019 | Journal of Thermal Science2019，28，4： | 4 |
| 16 | Method of moving target detection based on sub-image cancellation for single-antenna airborne synthetic aperture radar显示文摘The method of moving target detection based on subimage cancellation for single-antenna airborne SAR is presented.First the subimage is obtained through frequency processing is pointed out.The imaging difference of a stationary objects and moving object in the subimage based on the frequency division is analyzed from the fundamental principle.Then the developed method combines the shear averaging algorithm to focus on the moving target in the subimage,after the clutter suppression and the focusing position in each subimage is obtained. Next the observation model and the relative movement of the moving targets between the subimages estimate the moving targets.The theoretical analysis and simulation results demonstrate that the method is effective and can not only detect the moving targets,but also estimate their motion parameters precisely. | Liu Shujun Yuan Yunneng Gao Fei Mao Shiyi | 2007 | Journal of Systems Engineering and Electronics2007，18，3： | 4 |
| 17 | Proteomics study of Mycoplasma pneumoniae pneumonia reveals the Fc fragment of the IgG-binding protein as a serum biomarker and implicates potential therapeutic targets显示文摘Macrolide and corticosteroid resistance has been reported in patients with Mycoplasma pneumoniae(MP)pneumonia(MPP).MP clearance is difficult to achieve through antibiotic treatment in sensitive patients with severe MPP(SMPP).SMPP in children might progress to airway remodeling and even bronchiolitis/bronchitis obliterans.Therefore,identifying serum biomarkers that indicate MPP progression and exploring new targeted drugs for SMPP treatment require urgency.In this study,serum samples were collected from patients with general MPP(GMPP)and SMPP to conduct proteomics profiling.The Fc fragment of the IgG-binding protein(FCGBP)was identified as the most promising indicator of SMPP.Biological enrichment analysis indicated uncontrolled inflammation in SMPP.ELISA results proved that the FCGBP level in patients with SMPP was substantially higher than that in patients with GMPP.Furthermore,the FCGBP levels showed a decreasing trend in patients with GMPP but the opposite trend in patients with SMPP during disease progression.Connectivity map analyses identified 25 possible targeted drugs for SMPP treatment.Among them,a mechanistic target of rapamycin kinase(mTOR)inhibitor,which is a macrolide compound and a cell proliferation inhibitor,was the most promising candidate for targeting SMPP.To our knowledge,this study was the first proteomics-based characterization of patients with SMPP and GMPP. | Jinrong Liu Rongfang Shen Lin Feng Shujun Cheng Jun Chen Ting Xiao Shunying Zhao | 2022 | Frontiers of Medicine2022，16，3： | 3 |
| 18 | Extranodal involvement in young patients with diffuse large B-cell lymphoma: distribution, prognostic value and treatment options显示文摘Objective: Extranodal involvement represents a peculiar presentation of diffuse large B-cell lymphoma(DLBCL). Previous studies have suggested that older patients are more prone to extranodal involvement. This study retrospectively addressed the distribution, prognostic value and treatment options of extranodal involvement in young patients with DLBCL.Methods: A total of 329 patients were enrolled according to the inclusion requirements. The effects of gender,extranodal involvement, age-adjusted international prognostic index(aa IPI), rituximab infusion and radiotherapy on patient outcomes were evaluated.Results: Among these patients, 59% presented extranodal involvement in 16 anatomic sites. More than one instance was linked to many poorer clinical characteristics and poorer survival compared with either nodal disease or one instance. In patients with one extranodal lesion, multivariate analysis revealed that the site of extranodal involvement, but not the aa IPI or rituximab infusion, was independently related to the outcome, and radiotherapy had a negative influence on survival.Conclusions: Extranodal involvement is common in younger patients and exhibits a ubiquitous distribution.The site of extranodal involvement is of strong prognostic significance. Radiotherapy for extranodal lesions does not improve patient outcomes. | Shuna Yao Junbo Li Zhihua Yao Yuanlin Xu Junfeng Chu Jiuyang Zhang Shuiling Jin Yangyang Huang Jianbo Zhang Jie Ma Yan Zhao Shujun Yang Yanyan Liu | 2017 | Chinese Journal of Cancer Research2017，29，1： | 3 |
| 19 | Metabolism-independent chemotaxis of Pseudomonas sp. strain WBC-3 toward aromatic compounds显示文摘Pseudomonas sp. strain WBC-3 utilized methyl parathion or para-nitrophenol (PNP) as the sole source of carbon, nitrogen, and energy, and methyl parathion hydrolase had been previously characterized. Its chemotactic behaviors to aromatics were investigated. The results indicated that strain WBC-3 was attracted to multiple aromatic compounds, including metabolizable or transformable substrates PNP, 4-nitrocatechol, and hydroquinone. Disruption of PNP catabolic genes had no e?ect on its chemotactic behaviors with the same substrates, indicating that the chemotactic response in this strain was metabolism-independent. Furthermore, it was shown that strain WBC-3 had a constitutive β-ketoadipate chemotaxis system that responded to a broad range of aromatic compounds, which was different from the inducible β-ketoadipate chemotaxis described in other Pseudomonas strains. | ZHANG, Junjie XIN, Yufeng LIU, Hong WANG, Shujun ZHOU, Ningyi | 2008 | Journal of Environmental Sciences2008，20，10： | 3 |
| 20 | A new alternating copolymerized derivative as a cold flow improver for diesel fuel显示文摘Synthesis of a cold flow improver(MAVA-a) for diesel fuel and its effect on solidifying point(SP) and cold filter plugging point(CFPP) of diesel fuels were investigated.The cold flow improver was prepared by using maleic anhydride(MA) and vinyl acetate(VA) as raw materials,toluene as solvent,dibenzoyl peroxide(BPO) as initiator,through alternating polymerization under nitrogen to obtain a binary-polymer and then through aminolysis by using a higher carbon amine as aminating agent at a temperature of 80 °C.A cold flow improver was designed and prepared for No.0 diesel fuel from Zhang Jia-Gang Petrochemical Company according to the contents of n-paraffin and its carbon number distribution in the No.0 diesel fuel.It was also used together with two kinds of ethene-vinyl acetate copolymer improvers(EVA) separately.The test result showed that the CFPP of the No.0 diesel fuel could be lowered by 3-5 °C when the improver MAVA-a was used.The CFPP was lowered by 8 °C when the improver MAVA-a was used together with EVA-2. | ZHANG Haikuan LIU Hongyan WANG Shujun | 2009 | Petroleum Science2009，6，1： | 3 |
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