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| 1 | Stable classi?cation with limited sample: transferring a 30-m resolution sample set collected in 2015 to mapping 10-m resolution global land cover in 2017显示文摘As the world strives to reduce the impact of population growth, urbanization, agricultural expansion, and climate change on food security, energy and water shortage, resource over-exploration, biodiversity loss, environmental pollution, and ultimately human health, timely and higher resolution land cover information is urgently needed to achieve the sustainable development goals of the United Nations. | Peng Gong Han Liu Meinan Zhang Congcong Li Jie Wang Huabing Huang Nicholas Clinton Luyan Ji Wenyu Li Yuqi Bai Bin Chen Bing Xu Zhiliang Zhu Cui Yuan Hoi Ping Suen Jing Guo Nan Xu Weijia Li Yuanyuan Zhao Jun Yang Chaoqing Yu Xi Wang Haohuan Fu Le Yu Iryna Dronova Fengming Hui Xiao Cheng Xueli Shi Fengjin Xiao Qiufeng Liu Lianchun Song | 2019 | Science Bulletin2019，64，6： | 166 |
| 2 | Differentiation of bone marrow-derived mesenchymal stem cells from diabetic patients into insulin-producing cells in vitro显示文摘Bckground 干细胞,有能力区分进生产胰岛素的房间(欧洲电脑生产厂商) ,将为移植提供小岛房间的潜在地无限的来源并且减轻可获得性和 allogeneic 拒绝的主要限制。因此,干细胞的利用为糖尿病 mellitus (DM ) 正在成为最有希望的治疗。这里,我们学习了糖尿病的病人的骨头的区别能力导出髓的间充质的干细胞( MSC )并且测试了使用 MSC 的可行性因为房间 replacement.Methods 骨头导出髓的 MSC 从 10 个 DM 病人被获得( 5 打 1 DM , 5 打 2 DM )并且在一个三阶段的协议下面导致了到欧洲电脑生产厂商。MSC 的代表性的房间表面抗原表示侧面被流动 cytometric 分析分析。反向的抄写聚合酶链反应(RT-PCR ) 被执行检测与胰腺的房间开发和功能有关的多重基因。欧洲电脑生产厂商的身份被形态学, ditizone 染色和 immunocytochemistry 的分析说明。由这些房间的胰岛素的版本被 MSC 的 immunoradioassay.Results 流动 cytometric 分析在 3 显示出的经过证实这些房间表示了 CD29 (98.28%) 的高水平, CD44 (99.56%) 和 CD106 (98.34%) 。典型像小岛的房间簇在协议(18 天) 的结束被观察。染色的 Ditizone 和为胰岛素的 immunohistochemistry 两个都是积极的。在舞台 2 点的这些区分的房间(10 天) 表示了 nestin,胰腺的十二指肠的 homeobox-1 (PDX-1 ) , Neurogenin3, Pax4,胰岛素, glucagon,但是(18 天) 在舞台 3 点,我们观察了 PDX-1 的高表示,胰岛素, glucagon。胰岛素被这些房间以从 DM 病人的 .Conclusions 骨头导出髓的 MSC 能在 vitro 在某些条件下面区分进功能的欧洲电脑生产厂商的一种调整方式(P0.05 ) 响应葡萄糖刺激的不同集中分泌。用糖尿病的病人的自己的骨头,导出髓的 MSC 将作为为房间代替的自体同源的欧洲电脑生产厂商的来源是可行的。 | SUN Yu CHEN Li HOU Xin-guo HOU Wei-kai DONG Jian-jun SUN Lei TANG Kuan-xiao WANG Bin SONG Jun LI Hui WANG Ke-xin | 2007 | Chinese Medical Journal2007，，9： | 57 |
| 3 | Heavy metal pollution of soils and vegetables in the midstream and downstream of the Xiangjiang River, Hunan Province显示文摘219 农业土壤和 48 件蔬菜样品的一个总数在湖南省 Xiangjiang 河(Hengyang 长沙节) 从中流并且下游地被收集。累积特征。 | WANG Lixia GUO Zhaohui XIAO Xiyuan CHEN Tongbin LIAO Xiaoyong SONG Jie WU Bin | 2008 | Journal of Geographical Sciences2008，18，3： | 56 |
| 4 | Two submental island flaps for reconstructing oral and maxillofacial defects following cancer ablation显示文摘 | Wei Liang Chen Jin Song Li Zhao Hui Yang Jian Guang Wang Bin Zhang | 2008 | 中国口腔颌面外科杂志2008，6，B05： | 42 |
| 5 | Thrombus aspiration plus intra-infarct-related artery administration of tirofiban improves myocardial perfusion during primary angioplasty for acute myocardial infarction显示文摘我们开发了的背景加 intra-infarct-related 的血栓渴望的新联合策略经由在有圣片断举起的病人的渴望导管的 tirofiban 的动脉(IRA ) 大丸药管理心肌的梗塞(STEMI ) 。这策略能减少远侧的栓塞并且完成 tirofiban 的高度局部性的集中,没有增加流血的风险,它能改进心肌的灌注。这研究的目的在与经历二个组的主要 angioplasty.Results 基线特征的 STEMI 在病人改进心肌的灌注是调查这联合策略是否比血栓渴望优异独自一个的是正常的。TIMI 3 流动独自比在渴望在 intra-IRA 组显示出一个更好的趋势组(97.22% 对 87.04% , X^2=7.863, P=0.049 ) 。CK-MB 的山峰(83.9 (68.9-310.5 ) U/L 对 126.1 (74.7-356.7 ) U/L, P=0.034 ) 并且 Tnl (42.7 (14.7-113.9 ) ng/ml 对 72.5 (59.8-135.3 ) ng/ml, FMD.029 ) 独自比在渴望在 intra-IRA 组是更低的组。医院里的 LVEF 赞成了 intra-IRA 组,(45.7 湥獴眠瑩 ? 瑳 'L 敬愠杮湩 ? 慷 ? 潮 ? | YAN Hong-bing LI Shi-ying SONG Li WANG Jian WU Zheng CHI Yun-peng ZHENG Bin ZHAO Han-jun LI Qing-xiang ZHANG Xiao-jiang LI Wen-zheng | 2010 | Chinese Medical Journal2010，，7： | 50 |
| 6 | Noninvasive imaging of hepatocellular carcinoma: From diagnosis to prognosis显示文摘Hepatocellular carcinoma(HCC) is the most common primary liver cancer and a major public health problem worldwide. Hepatocarcinogenesis is a complex multistep process at molecular, cellular, and histologic levels with key alterations that can be revealed by noninvasive imaging modalities. Therefore, imaging techniques play pivotal roles in the detection, characterization, staging, surveillance, and prognosis evaluation of HCC. Currently, ultrasound is the first-line imaging modality for screening and surveillance purposes. While based on conclusive enhancement patterns comprising arterial phase hyperenhancement and portal venous and/or delayed phase wash-out, contrast enhanced dynamic computed tomography and magnetic resonance imaging(MRI) are the diagnostic tools for HCC without requirements for histopathologic confirmation. Functional MRI techniques, including diffusion-weighted imaging, MRI with hepatobiliary contrast agents, perfusion imaging, and magnetic resonance elastography, show promise in providing further important information regarding tumor biological behaviors. In addition, evaluation of tumor imaging characteristics, including nodule size, margin, number, vascular invasion, and growth patterns, allows preoperative prediction of tumor microvascular invasion and patient prognosis. Therefore, the aim of this article is to review the current state-of-the-art and recent advances in the comprehensive noninvasive imaging evaluation of HCC. We also provide the basic key concepts of HCC development and an overview of the current practice guidelines. | Han-Yu Jiang Jie Chen Chun-Chao Xia Li-Kun Cao Ting Duan Bin Song | 2018 | World Journal of Gastroenterology2018，24，22： | 37 |
| 7 | A nomogramfor predicting overall survival in patients with low-grade endometrial stromal sarcoma: A population-based analysis显示文摘Background:Low-grade endometrial stromal sarcoma(LG-ESS)is a rare tumor that lacks a prognostic prediction model.Our study aimed to develop a nomogram to predict overall survival of LG-ESS patients.Methods:A total of 1172 patients confirmed to have LG-ESS between 1988 and 2015 were selected from the Surveillance,Epidemiology and End Results(SEER)database.They were further divided into a training cohort and a validation cohort.The Akaike information criterion was used to select variables for the nomogram.The discrimination and calibration of the nomogram were evaluated using concordance index(C-index),area under time-dependent receiver operating characteristic curve(time-dependent AUC),and calibration plots.The net benefits of the nomogram at different threshold probabilities were quantified and compared with those of the International Federation of Gynecology and Obstetrics(FIGO)criteria-based tumor staging using decision curve analysis(DCA).Net reclassification index(NRI)and integrated discrimination improvement(IDI)were also used to compare the nomogram’s clinical utilitywith that of the FIGO criteria-based tumor staging.The risk stratifications of the nomogram and the FIGO criteria-based tumor staging were compared.Results:Seven variables were selected to establish the nomogram for LG-ESS.The C-index(0.814 for the training cohort and 0.837 for the validation cohort)and the time-dependent AUC(>0.7)indicated satisfactory discriminative ability of the nomogram.The calibration plots showed favorable consistency between the prediction of the nomogram and actual observations in both the training and validation cohorts.The NRI values(training cohort:0.271 for 5-year and 0.433 for 10-year OS prediction;validation cohort:0.310 for 5-year and 0.383 for 10-year OS prediction)and IDI(training cohort:0.146 for 5-year and 0.185 for 10-year OS prediction;validation cohort:0.177 for 5-year and 0.191 for 10-year OS prediction)indicated that the established nomogram performed significantly better than the FIGO criteria-based tumor staging alone(P<0.05).Furthermore,DCA showed that the nomogram was clinically useful and had better discriminative ability to recognize patients at high risk than the FIGO criteria-based tumor staging.Conclusions:A prognostic nomogram was developed and validated to assist clinicians in evaluating prognosis of LG-ESS patients. | Jie Wu Huibo Zhang Lan Li Mengxue Hu Liang Chen Bin Xu Qibin Song | 2020 | Cancer Communications2020，40，7： | 35 |
| 8 | Variation of Cd concentration in various rice cultivars and derivation of cadmium toxicity thresholds for paddy soil by species-sensitivity distribution显示文摘It is imperative to derive an appropriate cadmium(Cd) health risk toxicity threshold for paddy soils to ensure the Cd concentration of rice grains meet the food safety standard. In this study, 20 rice cultivars from the main rice producing areas in China were selected, and a pot-experiment was conducted to investigate transformation of Cd in paddy soil-rice system with 0(CK), 0.3 mg kg–1(T1) and 0.6 mg kg–1(T2) Cd treatments in greenhouse. The results showed that Cd concentrations of rice grains existed significant difference(P<0.05) in 20 rice cultivars under the same Cd level in soil. The Cd concentrations of rice grains of the CK, T1 and T2 treatments were in the range of 0.143–0.202, 0.128–0.458 and 0.332–0.806 mg kg–1, respectively. Marked differences of the ratios of Cd concentration for soil to rice grain(BCFs) and transfer factors(TFs, root to grain and straw to grain) among the tested cultivars were observed in this study. The bioconcentration factors(BCFgrain) and TFs of the 20 rice cultivars were 0.300–1.112 and 0.342–0.817, respectively. The TFs of Cd from straw to grain ranged from 0.366 to 1.71, with significant differences among these 20 rice cultivars. The bioconcentration factors(BCFgrain) and TFs among the 20 rice cultivars ranged from 0.300–1.112 and 0.342–0.817, respectively. The species-sensitivity distribution(SSD) of Cd sensitivity of the rice species could be fitted well with Burr-III(R2=0.987) based on the data of BCFs. The toxicity threshold of Cd derived from SSD for the paddy soil was 0.507 mg kg–1 in the present study. | SONG Wen-en CHEN Shi-bao LIU Ji-fang CHEN Li SONG Ning-ning LI Ning LIU Bin | 2015 | Journal of Integrative Agriculture2015，14，9： | 33 |
| 9 | ^40Ar/^39Ar and Rb-Sr Ages of the Tiegelongnan Porphyry Cu-(Au)Deposit in the Bangong Co-Nujiang Metallogenic Belt of Tibet,China:Implication for Generation of Super-Large Deposit显示文摘The Tiegelongnan deposit is a newly discovered super-large porphyry-epithermal Cu-(Au) deposit in the western part of the Bangong Co-Nujiang metallogenic belt, Tibet(China). Field geology and geochronology indicate that the porphyry mineralization was closely related to the Early Cretaceous intermediate-felsic intrusions(ca. 123–120 Ma). Various epithermal ore and gangue mineral types were discovered in the middle-shallow part of the orebody, indicating the presence of epithermal mineralization at Tiegelongnan. Potassic, propylitic, phyllic and advanced argillic alteration zones were identified. ^(40)Ar/^(39)Ar dating of hydrothermal biotite(potassic zone), sericite(phyllic zone), and alunite(advanced argillic zone) in/around the ore-bearing granodiorite porphyry yielded 121.1±0.6 Ma(1σ), 120.8±0.7 Ma(1σ) and 117.9±1.6 Ma(1σ), respectively. Five hydrothermal mineralization stages were identified, of which the Stage IV pyrite was Rb-Sr dated to be 117.5±1.8 Ma(2σ), representing the end of epithermal mineralization. Field geology and geochronology suggest that both the epithermal and porphyry mineralization belong to the same magmatic-hydrothermal system. The Tiegelongnan super-large Cu-(Au) deposit may have undergone a prolonged magmatichydrothermal evolution, with the major mineralization event occurring at ca.120–117Ma. | LIN Bin CHEN Yuchuan TANG Juxing WANG Qin SONG Yang YANG Chao WANG Wenlei HE Wen ZHANG Lejun | 2017 | Acta Geologica Sinica(English Edition)2017，91，2： | 33 |
| 10 | Shortened Basal Internodes Encodes a Gibberellin 2-Oxidase and Contributes to Lodging Resistance in Rice显示文摘改进住宿抵抗的繁殖半矮子变化被证明了在自从绿 revolution.?However 的来临,增加谷物产量极其成功,在亚洲繁殖半矮子米饭变化的多数主要依赖于 SD1 的变异的等位基因的基因介绍,它编码赤霉素( GA ) 20-oxidase , OsGA20ox2 ,为催化 GA 生合成。这里,我们报导新米饭住宿抵抗基因,弄短的基础 Internodes (SBI ) ,它编码赤霉素 ? 2-oxidase 并且明确地控制灰煤杆的延伸通过撤销的基础 internodes GA 活动。SBI 主要在灰煤杆被表示基础 internodes。基因分析显示 SBI 是影响米饭高度和住宿抵抗的半主导的基因。SBI 突变而产生之遗传的变体显示不同活动并且与米饭变化的高度被联系。与 SBI 等位基因的更高的活动繁殖与改进住宿抵抗和增加的产量产生新米饭变化。SBI 的发现为生产半矮子米饭显型提供一个理想的基因资源并且为与提高的住宿抵抗和高产量引起米饭变化提供有效策略。 | Chang Liu Jinshan Gui Chenjian Fu Hasi Yu Dongliang Song Junhui Shen Peng Qin Xuanming Liu Bin Han Yuanzhu Yang Laigeng Li | 2018 | Molecular Plant2018，11，2： | 33 |
| 11 | Extracellular heat-shock protein 70 aggravates cerulein-induced pancreatitis through toll-like receptor-4 in mice显示文摘在受不了尖锐胰腺炎的病人,的背景致病完全没被理解,并且在 vitro 的几最近的研究建议热吃惊蛋白质可能在房间发信号起一个重要作用。在胰腺炎调查细胞外的热吃惊蛋白质 70 的可能的角色( Hsp70 ),像使用费的 receptor-4 ( TLR4 )缺乏、野类型的老鼠在 导致cerulein 的胰腺炎( CIP )的功课期间与外长的 Hsp70 被管理 .Methods 尖锐胰腺炎被 cerulein 的 5 intraperitoneal 注射导致在时时间隔,然后通过尾的静脉与 recombinant 对待 Hsp70 在 cerulein 注射的开始以后的 4 个小时。随后,浆液淀粉酶和浆液 cytokines 层次被检测。胰的 Histologic 改变被评估。肿瘤坏死因素 alpha (TNF -- 一) 集中和 myeloperoxidase (军邮局) 在胰和肺的活动被分析。在胰腺的织物的原子因素 kappa B ( NF-KB )激活在 CIP 与 recombinant Hsp70 用一个敏感 RelA 连接酶的 immunosorbent assay.Results 处理被测量到野类型的老鼠在胰导致了发炎的重要恶化,浆液 cytokines 的提高的层次,肺的军邮局活动的起来规定和肺纸巾TNF-集中的增加。相反,有到TLR4缺乏的老鼠的 Hsp70 的处理在浆液 cytokines 层次上有小效果,胰腺的发炎,肺的军邮局活动和 TNF -- concentrations.Conclusions 结果建议细胞外的 HspTO 可能导致全身的煽动性的反应没有感染,在 vivo 和 TLR4 的症候群(先生) -Iike 反应可能在 CIP 的前进涉及煽动性的反应的 调停Hsp70 的激活。 | SONG Jun-min LIU Hong-xiang LI Yuan ZENG Yu-jian ZHOU Zong-guang LIU Hai-yi XU Bing WANG Ling ZHOU Bin WANG Rong | 2008 | Chinese Medical Journal2008，，15： | 27 |
| 12 | Comparison of Diver CE and ZEEK manual aspiration catheters for thrombectomy in ST-segment elevation myocardial infarction显示文摘数据的背景 A 成长体积建议直接 stenting 跟随的简单用手的血栓渴望与常规主要一种总线标准相比改进心肌的灌注和临床的结果,但是仍然有有限数据,比较在里面在不同设备之中的 vivo 性能。这研究试图由 Diver CE 比较血栓渴望的功效和操作性( Invatec , Brescia ,意大利 )并且 ZEEK ( Zeon 医药公司,东京,日本)在圣片断举起的渴望导管心肌的梗塞( STEMI )和他们到2008年6月的从2004年9月的3月的 outcome.Methods 上的影响,收到了用手的血栓渴望的有 STEMI 的 298 个连续病人涉及一个单个中心回顾的分析。他们, 229 和 69 分别地与 Diver CE 和 ZEEK 渴望导管被对待。主要端点是心肌的脸红等级(MBG ) ,在心肌的梗塞(TIMI ) 的 thrombolysis 流动等级,圣片断举起决定(STR ) ,设备 pushability 和由由把发成送气音的血栓症的尺寸分发显示了的双指南电线和渴望功效的用法的频率判定了的可跟踪性。第二等的端点是包括左室的结束的3月的结果心脏舒张的直径( LVEDD ),左室的喷射部分( LVEF ),以及心脏的死亡,目标损害 revascularization ( TLR ),主要不利心脏的事件(向) .Results 基线特征不在二个组之间是不同的重新梗塞和他们的联合为比在 Diver CE 组( Diver CE )的在 ZEEK 组( ZEEK )的暂时的心脏的踱步的更高的频率期望(0.44%对5.8%, P=0.002 )。可见检索血栓症在 65.9% Diver CE 和 68.1% ZEEK (P=0.74 ) 被完成。把发成送气音的血栓症作为小血栓症被分类(< 3.5 公里) ,中等血栓症(3.5-7.0 公里) 和大血栓症(> 7.0 公里) 。小血栓症是经常在 Diver CE (61.6% 对 42.6%) 看见的更多,而中等、更大的血栓症更经常在 ZEEK (38.4% 对 57.4%)(P=0.021 ) 被发现。双电线利用的率是 1.7% Diver CE 和 7.2% ZEEK (P=0.052 ) 。在在二个组之间的 MBG, STR 和 TIMI 流动等级没有差别。没有差别两个都在 3 月的 follow-up.Conclusions 期间在在 Diver CE 和 ZEEK 之间的心脏的死亡, TLR,重新梗塞,向, LVEDD 和 LVEF 被发现 Diver CE 和 ZEEK 用手的渴望导管为在 STEMI 的 thrombectomy 是有效的。在临床的实践, ZEEK 介绍一个更强壮的渴望能力为与 Diver CE,而是 Diver CE 显示相比节制到大血栓症向更好的 pushability 和可跟踪性的一个趋势比 ZEEK。在在在这个背景的 Diver CE 和 ZEEK 之间的渴望能力和操作性的差别不影响心肌的灌注和 3 月的结果。 | ZHAO Han-jun YAN Hong-bing WANG Jian SONG Li LI Qing-xiang LI Shi-ying CHI Yun-peng WU Zheng ZHANG Xiao-jiang ZHAO Yong ZHENG Bin | 2009 | Chinese Medical Journal2009，，6： | 25 |
| 13 | ZIKA virus isolated from mosquitoes:a field and laboratory investigation in China,2016显示文摘A field investigation of arboviruses was conducted in Dejiang, Guizhou Province in the summer of 2016. A total of 8,795 mosquitoes, belonging to four species of three genera, and 1,300 midges were collected. The mosquito samples were identified on site according to their morphology, and the pooled samples were ground and centrifuged in the laboratory. The supernatant was incubated with mosquito tissue culture cells(C6/36) and mammalian cells(BHK-21) for virus isolation. The results indicated that 40%(3,540/8,795) were Anopheles sinensis, 30%(2,700/8,795) were Culex pipiens quinquefasciatus, and 29%(2,530/8,795)were Armigeres subbalbeatus. Furthermore, a total of eight virus isolates were obtained, and genome sequencing revealed two Zika viruses(ZIKVs) isolated from Culex pipiens quinquefasciatus and Armigeres subbalbeatus, respectively; three Japanese encephalitis viruses(JEVs) isolated from Culex pipiens quinquefasciatus; two Banna viruses(BAVs) isolated from Culex pipiens quinquefasciatus and Anopheles sinensis, respectively; and one densovirus(DNV) isolated from Culex pipiens quinquefasciatus.The ZIKVs isolated from the Culex pipiens quinquefasciatus and Armigeres subbalbeatus mosquitoes represent the first ZIKV isolates in China's Mainland. This discovery presents new challenges for the prevention and control of ZIKV in China, and prompts international cooperation on this global issue. | Shihong Fu Song Song Hong Liu Yuanyuan Li Xiaolong Li Xiaoyan Gao Ziqian Xu Guoping Liu Dingming Wang Zhenzao Tian Jingzhu Zhou Ying He Wenwen Lei Huanyu Wang Bin Wang Xiaoqing Lu Guodong Liang | 2017 | Science China(Life Sciences)2017，60，12： | 25 |
| 14 | The Chrysanthemum nankingense Genome Provides Insights into the Evolution and Diversification of Chrysanthemum Flowers and Medicinal Traits显示文摘The Asteraceae (Compositae),a large plant family of approximately 24 000-35 000 species,accounts for^10% of all angiosperm species and contributes a lot to plant diversity.The most representative members of the Asteraceae are the economically important chrysanthemums (Chrysanthemum L.)that diversified through reticulate evolution.Biodiversity is typically created by multiple evolutionary mechanisms such as wholegenome duplication 0NGD)or polyploidization and locally repetitive genome expansion.However,the lack of genomic data from chrysanthemum species has prevented an in-depth analysis of the evolutionary mechanisms involved in their diversification.Here,we used Oxford Nanopore long-read technologyto sequence the diploid Chrysanthemum nankingense genome,which represents one of the progenitor genomes of domesticated chrysanthemums.Our analysis revealed that the evolution of the C.nankingense genome was driven by bursts of repetitive element expansion and WGD events including a recentWGD that distinguishes chrysanthemum from sunflower,which diverged from chrysanthemum approximately 38.8 million years ago.Variations of ornamental and medicinal traits in chrysanthemums are linked to the expansion of candidate gene families by duplication events including paralogous gene duplication.Collectively,our study of the assembled reference genome offers new knowledge and resources to dissect the history and pattern of evolution and diversification of chrysanthemum plants,and also to accelerate their breeding and improvement. | Chi Song Yifei Liu Aiping Song Gangqiang Dong Hongbo Zhao Wei Sun Shyam Ramakrishnan Ying Wang Shuaibin Wang Tingzhao Li Yan Niu Jiafu Jiang Bin Dong Ye Xia Sumei Chen Zhigang Hu Fadi Chen Shilin Chen | 2018 | Molecular Plant2018，11，12： | 24 |
| 15 | Superficial temporal artery-middle cerebral artery bypass combined with encephalo-duro-myo-synangiosis in treating moyamoya disease: surgical techniques, indications and midterm follow-up results显示文摘 | XU Bin SONG Dong-lei MAO Ying GU Yu-xiang XU Hong LIAO Yu-jun LIU Chuang-hong ZHOU Liang-fu | 2012 | Chinese Medical Journal2012，，24： | 22 |
| 16 | The second natural gas hydrate production test in the South China Sea显示文摘Clayey silt reservoirs bearing natural gas hydrates(NGH)are considered to be the hydrate-bearing reservoirs that boast the highest reserves but tend to be the most difficult to exploit.They are proved to be exploitable by the first NGH production test conducted in the South China Sea in 2017.Based on the understanding of the first production test,the China Geological Survey determined the optimal target NGH reservoirs for production test and conducted a detailed assessment,numerical and experimental simulation,and onshore testing of the reservoirs.After that,it conducted the second offshore NGH production test in 1225 m deep Shenhu Area,South China Sea(also referred to as the second production test)from October 2019 to April 2020.During the second production test,a series of technical challenges of drilling horizontal wells in shallow soft strata in deep sea were met,including wellhead stability,directional drilling of a horizontal well,reservoir stimulation and sand control,and accurate depressurization.As a result,30 days of continuous gas production was achieved,with a cumulative gas production of 86.14×104 m3.Thus,the average daily gas production is 2.87×10^4 m^3,which is 5.57 times as much as that obtained in the first production test.Therefore,both the cumulative gas production and the daily gas production were highly improved compared to the first production test.As indicated by the monitoring results of the second production test,there was no anomaly in methane content in the seafloor,seawater,and atmosphere throughout the whole production test.This successful production test further indicates that safe and effective NGH exploitation is feasible in clayey silt NGH reservoirs.The industrialization of hydrates consists of five stages in general,namely theoretical research and simulation experiments,exploratory production test,experimental production test,productive production test,and commercial production.The second production test serves as an important step from the exploratory production test to experimental production test. | Jian-liang Ye Xu-wen Qin Wen-wei Xie Hai-long Lu Bao-jin Ma Hai-jun Qiu Jin-qiang Liang Jing-an Lu Zeng-gui Kuang Cheng Lu Qian-yong Liang Shi-peng Wei Yan-jiang Yu Chunsheng Liu Bin Li Kai-xiang Shen Hao-xian Shi Qiu-ping Lu Jing Li Bei-bei Kou Gang Song Bo Li He-en Zhang Hong-feng Lu Chao Ma Yi-fei Dong Hang Bian | 2020 | China Geology2020，3，2： | 22 |
| 17 | Hilar cholangiocarcinoma:preoperative evaluation with a three dimensional volumetric interpolated breath-hold examination magnetic resonance imaging sequence显示文摘背景早察觉和精确阶段为计划处理和 hilar cholangiocarcinomas 的改善幸存率是关键的。这研究调查了三维的、宠坏的坡度回响的诊断价值, T1 加权的磁性的回声(先生) 成像顺序(3D 容量的插入内推的呼吸抓住检查, 3D-VIBE ) 在 hilar cholangiocarcinoma.Methods 的外科手术前的评估,有通过手术并且组织学地证实的 hilar cholangiocarcinomas 的 31 个病人经历了外科手术前的先生成像检查。Unenhanced 二维的 T1 加权、 T2 加权的图象, 2D 先生 cholangiopancreatographs (MRCP ) ,金轧提高了 3D-VIBE 图象在早动脉,晚动脉并且静脉的阶段由在平衡的 T1 加权的图象分阶段执行的 2D 跟随了的门被获得。从 3D-VIBE 的图象, 2D T1 加权的提高的序列和 2D MRCP 被二个腹的放射线学者通过以盲目方式读的一致解释,集中于对词法类型的评价,在胆汁管和附近的血容器的参与的肿瘤渗入的纵的程度。3D-VIBE 和 2D 的精确性在估计肿瘤 resectability 的 T1 加权的提高的序列是 compared.Results 而,所有 31 个肿瘤直接在 3D-VIBE 上被显示并且精确地分类图象 8 periductal 渗透肿瘤(8/31, 25.8%) 没在 2D 上被描绘 T1 加权的提高的图象。用铋 Corlette 分类, 3D-VIBE 在描出接近了 MRCP 肿瘤渗入的 intraductal 程度比 2D T1 加权提高(28/31, 90.3% ;10/31,32.3% ;2=22.0, P0.05 ) 。肝的动脉的参与,静脉的箱子和他们的分支比 2D 在 3D VIBE 上更经常被显示出的门 T1 加权的提高的图象。3D-VIBE 的积极预兆的价值和精确性(84.2% ;90.3%) 为估计肿瘤, resectability 比 2D 的那些高 T1 加权的提高的图象(64.0% ;71.0% ,所有 P0.05 ).Conclusion 金轧提高了 3D-VIBE 比 2D 好在对 morphologicalal 类型,渗入程度的 intraductal 和 hilar cholangiocarcinomas 的肿瘤 resectability 的外科手术前的评价的 T1 加权的提高的顺序。 | YIN Long-lin SONG Bin XU Juan LI Ying-chun | 2007 | Chinese Medical Journal2007，，8： | 21 |
| 18 | Closed reduction and internal fixation versus total hip arthroplasty for displaced femoral neck fracture显示文摘ObjectiveTo 为代替的大腿骨的颈 fracture.MethodsIn 比较在关上的减小和内部固定和全部的新潮的关节造形术(THA )(CRIF ) 之间的临床的效果这未来的使随机化的研究,与新潮的破裂(花园 III 或 IV ) 在 65 年上面变老的 285 个病人从 2001 年 1 月被包括到 2005 年 12 月。盒子随机被分配到 CRIF 组或 THA 组。有病理学的破裂(骨头肿瘤或新陈代谢的骨头疾病)的病人,大腿骨的头的外科手术前的 avascular 坏死,骨关节炎,风湿性关节炎,半身麻痹,长期的病床休息和影响新潮的功能的复杂并发症是 excluded.ResultsDuring 5年的后续,有的 CRIF 组更高显著地在新潮的关节复杂并发症评价,一般复杂并发症和操作比 THA 组织(38.3%对12.7%, P ;< ; 0.01 ;45.3% 对 21.7% , P < 0.01;33.6% 对 10.2% , P < 0.05 分别地) 。在在二个组之间的死亡没有差别。在与更高级的哈里斯 scores.ConclusionFor 有利地恢复的 THA 组的新潮的关节的手术后的功能在老病人,代替了大腿骨的颈的破裂 THA 能完成复杂并发症和操作的更低的率,以及新潮的联合功能的更好手术后的恢复与 CRIF 相比。 | Cao Liehu Wang Bin Li Ming Song Shaojun Weng Weizong Li Haihang Su Jiacan | 2014 | Chinese Journal of Traumatology2014，17，2： | 21 |
| 19 | Deterministic secure quantum communication over a collective-noise channel显示文摘We present two deterministic secure quantum communication schemes over a collective-noise. One is used to complete the secure quantum communication against a collective-rotation noise and the other is used against a collective-dephasing noise. The two parties of quantum communication can exploit the correlation of their subsystems to check eavesdropping efficiently. Although the sender should prepare a sequence of three-photon entangled states for accomplishing secure communication against a collective noise,the two parties need only single-photon measurements,rather than Bell-state measurements,which will make our schemes convenient in practical application. | GU Bin PEI ShiXin SONG Biao ZHONG Kun | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，12： | 20 |
| 20 | A huge oceanic-type UHP metamorphic belt in southwestern Tianshan, China: Peak metamorphic age and P-T path显示文摘Recent progress in the study of the UHP metamorphic belt in southwestern Tianshan,China,is summarized in this paper.This about 80-km-long and over 10-km-wide UHP belt has been recognized by the discovery of coesite,coesite pseudomorphs and other UHP minerals.It is the largest oceanic-type UHP metamorphic belt reported so far.It has formed due to northward subduction of the Tianshan Paleo-Ocean.U-Pb dating of metamorphic rims of zircons from a coesite-bearing garnet-phengite schist yields a peak UHP metamorphic ages of 320±3.7 Ma.Combined with ages of 233–226 Ma obtained from rims of zircons from retrograded eclogites,a long retrograde metamorphic evolution(>70 Ma)has been revealed.According to phase equilibria modeling,the P-T paths of both coesite-bearing eclogites and garnet-phengite schists are characterized by thermal relaxation,i.e.,the metamorphic temperature peak lags behind the pressure peak,indicating that the UHP rocks experienced slow and long heating and decompression during exhumation in the subduction channel.On the basis of the field observation that a small amount of eclogite lenses is wrapped in large volumes of metapelites,and the similar P-T paths of both rock types,we propose that the exhumation of the UHP eclogites from southwestern Tianshan,China,may have resulted from the exhumation of large volumes of low-density metapelites,which carried the denser eclogites to the Earth’s surface. | ZHANG LiFei DU JinXue Lü Zeng YANG Xin GOU LongLong XIA Bin CHEN ZhenYu WEI ChunJing SONG ShuGuang | 2013 | Chinese Science Bulletin2013，58，35： | 19 |
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