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| 1 | Assimilation of carbonate country rock by the parent magma of the Panzhihua Fe-Ti-V deposit(SW China):Evidence from stable isotopes显示文摘在西南中国的 Panzhihua 侵入是 Emeishan 大火的省的部分和大 Fe-Ti-V 矿石存款的主人。在主要侵入的炮兵阵地期间, mafic 女同性恋的多重代入侵了碳酸盐墙岩石,生产一个大接触光环。我们测量了国家岩石的侵入,他们的成分矿物质,和样品的氧同位素作文。从 Panzhihua 侵入的磁铁矿和斜长石有与 magmatic 平衡一致,并且比在导出披风的岩浆期望与高是 12 的 18O 价值从岩浆形成的 18O 价值。unmetamorphosed 国家岩石有高 18O 价值,从 13.2 (沙岩) 到 24.628.6 (白云石) 。从光环的 skarns 和云石比他们与在有邻近的 mafic 岩浆和侵入的特别众多的 mafic 女同性恋的交换平衡的液体建议相互作用的 protolith 有更低的 18O 和 13C 价值光环。这将比为导出披风的岩浆期望解释有显著地更高的价值的女同性恋的 18O 的改变。取决于为岩浆和沾染物假定的准确 18O 价值,要求生产 Panzhihua 侵入的提高的 18O 价值的吸收的数量在 8 和 13.7 wt.% 之间,假定简单混合。污染的准确机制是不清楚的,但是可以包含体积国家岩石的吸收的联合,混合与一有 CO2 富有的液体的国家岩石和交换的 melt 源于泥土和白云石的 decarbonation。这些机制,特别地后者,可能涉及 Fe-Ti-V 矿石的形成。 | Clement Ganino Chris Harris Nicholas T.Arndt Stephen A.Prevec Geoffrey H.Howarth | 2013 | Geoscience Frontiers2013，4，5： | 20 |
| 2 | Bone morphogenetic protein-2 gene controls tooth root development in coordination with formation of the periodontium显示文摘Formation of the periodontium begins following onset of tooth-root formation in a coordinated manner after birth. Dental follicle progenitor cells are thought to form the cementum, alveolar bone and Sharpey's fibers of the periodontal ligament (PDL). However, little is known about the regulatory morphogens that control differentiation and function of these progenitor cells, as well as the progenitor cells involved in crown and root formation. We investigated the role of bone morphogenetic protein-2 (Bmp2) in these processes by the conditional removal of the Bmp2 gene using the Sp7-Cre-EGFP mouse model. Sp7-Cre-EGFP first becomes active at E18 in the first molar, with robust Cre activity at postnatal day 0 (P0), followed by Cre activity in the second molar, which occurs after P0. There is robust Cre activity in the periodontium and third molars by 2 weeks of age. When the Bmp2 gene is removed from Sp7+ (Osterix+) cells, major defects are noted in root, cellular cementum and periodontium formation. First, there are major cell autonomous defects in root-odontoblast terminal differentiation. Second, there are major alterations in formation of the PDLs and cellular cementum, correlated with decreased nuclear factor IC (Nfic), periostin and α-SMA+ cells. Third, there is a failure to produce vascular endothelial growth factor A (VEGF-A) in the periodontium and the pulp leading to decreased formation of the microvascular and associated candidate stem cells in the Bmp2-cKOSp7-Cre-EGFP . Fourth, ameloblast function and enamel formation are indirectly altered in the Bmp2-cKOSp7-Cre-EGFP . These data demonstrate that the Bmp2 gene has complex roles in postnatal tooth development and periodontium formation. | Audrey Rakian Wu-Chen Yang Jelica Gluhak-Heinrich Yong Cui Marie A Harris Demitri Villarreal Jerry Q Feng Mary MacDougall Stephen E Harris | 2013 | International Journal of Oral Science2013，5，2： | 14 |
| 3 | 红曲对中度血脂升高美国人调节血脂作用的临床研究显示文摘[目的]评价在饮食控制的情况下红曲(RYRCholestin)对美国高血脂人群的降脂作用和安全性。[方法]开放标记,自身对照,多中心临床试验。187名美国高血脂人群入选(血清低密度脂蛋白胆固醇3.50—4.92mmol/L,总胆固醇5.18—7.25mmol/L;男116人,女71人),162入完成试验。在整个试验中受试者遵照美国国家胆固醇教育计划的饮食要求。试验的前4周仅控制饮食,第5周至第12周连续服用8周RYRCholestin(每日2.4g)。[结果]经前4周饮食控制,血清脂质各指标无显著变化。口服RYRCholestin8周后,血清总胆固醇、低密度脂蛋白胆固醇和三酰甘油分别降低16.6%,24.O%和25.2%,高密度脂蛋白胆固醇升高14.3%(P〈0.001)。显效率为79.0%,有效率为97.5%。停服14d(2周)后,血脂各指标回到试验前水平。试验中共发现可能与服用产品相关的、轻度的29项不良反应。[结论]RYRCholestin的耐受性良好,它可降低血清总胆固醇、低密度脂蛋白胆固醇和三酰甘油,升高血清高密度脂蛋白胆固醇。停服2用后受试者的血脂各项指标均恢复到试验前水平。 | 陆继红 Kermit Bonovich Harry Colfer Michael Davidson Carlos A.Dujovne David L.Fried Mitchell Greenspan Ronald P.Karlsberg Stephen P.King Craig F.LaForce Marc Litt J.Robert McGhee 曾润海 朱佳石 谈宁芝 | 2013 | 上海预防医学2013，25，9： | 5 |
| 4 | Hepatitis B surface antigen quantification: Why and how to use it in 2011 – A core group report显示文摘 | Henry Lik-Yuen Chan Alex Thompson Michelle Martinot-Peignoux Teerha Piratvisuth Markus Cornberg Maurizia Rossana Brunetto Hans L. Tillmann Jia-Horng Kao Ji-Dong Jia Heiner Wedemeyer Stephen Locarnini Harry L.A. Janssen Patrick Marcellin | 2011 | Journal of Hepatology2011，，5： | 5 |
| 5 | Unique microRNA molecular profiles in lung cancer diagnosis and prognosis显示文摘 | Nozomu Yanaihara Natasha Caplen Elise Bowman Masahiro Seike Kensuke Kumamoto Ming Yi Robert M. Stephens Aikou Okamoto Jun Yokota Tadao Tanaka George Adrian Calin Chang-Gong Liu Carlo M. Croce Curtis C. Harris | 2006 | Cancer Cell2006，，3： | 4 |
| 6 | Human dNK cell function is differentially regulated by extrinsic cellular engagement and intrinsic activating receptors in first and second trimester pregnancy显示文摘蜕膜的生来的杀手(dNK ) 房间表示一连串的激活受体在早怀孕期间调整胎盘的免疫和开发。我们在在 dNK 和 trophoblast 房间之间的怀孕期和相互作用的第一和第二个三个月期间调查了人的 dNK 房间的功能的特性。尽管 CD56 + 在全部的 CD45 + 白血球之中的 CD16 − dNK 没在这个句号,激活的受体的表示, NKp80 和 NKG2D 上变化,极大地 upregulated。我们与第二三个月蜕膜比较在第一个三个月在最近观察了 extravillous trophoblast 房间的一个显著地更高的数字到 dNK 房间。当 co 有教养时,由第一个三个月 dNK 房间的 NKG2D 表示与 HTR-8 trophoblast 房间线被减少。在第二个三个月, dNK 激活的功能的标记,即, angiogenic 因素生产(例如,脉管的 endothelial 生长因素, interleukin-8, interferon-gamma ) ,尽管有 NKp80 或 NKG2D 表面表示的增加的仍然是的马厩。而且, dNK 房间的 degranulation 能力由 CD107a 估计了在第二个三个月被减少。我们建议在第一个三个月, trophoblast-dNK 相互作用与压制的激活的显型产生 dNK 房间的一张人口。在第二个三个月, trophoblast-dNK 相互作用的损失导致了 dNK 房间功能的抑制,尽管他们的激活的受体表示被增加。我们推测在怀孕期间,二机制操作调制激活受体的 dNK 房间 activation:suppression,这由在第二个三个月联合的 receptor-ligand 的 trophoblasts 和解开在第一个三个月铺平。 | Jianhong Zhang Caroline E Dunk Melissa Kwan Rebecca L Jones Lynda K Harris Sarah Keating Stephen J Lye | 2017 | Cellular & Molecular Immunology2017，14，2： | 4 |
| 7 | Tracking Groups of People显示文摘 | Stephen J. McKenna Sumer Jabri Zoran Duric Azriel Rosenfeld Harry Wechsler | 2000 | Computer Vision and Image Understanding2000，，1： | 2 |
| 8 | Unique microRNA molecular profiles in lung cancer diagnosis and prognosis显示文摘 | Nozomu Yanaihara Natasha Caplen Elise Bowman Masahiro Seike Kensuke Kumamoto Ming Yi Robert M. Stephens Aikou Okamoto Jun Yokota Tadao Tanaka George Adrian Calin Chang-Gong Liu Carlo M. Croce Curtis C. Harris | 2006 | Cancer Cell2006，，3： | 2 |
| 9 | Signature size distributions for diesel and gasoline engine exhaust particulate matter显示文摘 | Stephen J. Harris M.Matti Maricq | 2001 | Journal of Aerosol Science2001，，6： | 2 |
| 10 | Mississippian Barnett Formation, Fort Worth Basin, Texas: Bulk geochemical inferences and Mo–TOC constraints on the severity of hydrographic restriction显示文摘 | Harry D. Rowe Robert G. Loucks Stephen C. Ruppel Susan M. Rimmer | 2008 | Chemical Geology2008，，： | 2 |
| 11 | Stephen C. Angle and Michael Slote, eds. Virtue Ethics and Confucianism. New York and London: Routledge, 2013.27 lpp., ISBN: 9780415815482.显示文摘 | Stephen Harris | 2015 | Frontiers of Philosophy in China2015，10，1： | 2 |
| 12 | A combined corner and edge detector显示文摘 | Harris C Stephens M | 1988 | Alvey Vision Conf1988，，： | 1 |
| 13 | A Variable-dosing Regimen with Intravitreal Ranibizumab for Neovascular Age-related Macular Degeneration: Year 2 of the PrONTO Study显示文摘 | Geeta A. Lalwani Philip J. Rosenfeld Anne E. Fung Sander R. Dubovy Stephen Michels William Feuer Janet L. Davis Harry W. Flynn Maria Esquiabro | 2009 | American Journal of Ophthalmology2009，，1： | 1 |
| 14 | Lactobacilli and bifidobacteria in the prevention of antibiotic-associated diarrhoea and Clostridium difficile diarrhoea in older inpatients (PLACIDE): a randomised, double-blind, placebo-controlled, multicentre trial显示文摘 | Stephen J Allen Kathie Wareham Duolao Wang Caroline Bradley Hayley Hutchings Wyn Harris Anjan Dhar Helga Brown Alwyn Foden Michael B Gravenor Dietrich Mack | 2013 | The Lancet . 2013 (9900)2013，，9900： | 1 |
| 15 | Sarcopenic obesity: definition, cause and consequences显示文摘 | Sari Stenholm Tamara B Harris Taina Rantanen Marjolein Visser Stephen B Kritchevsky Luigi Ferrucci | 2008 | Current Opinion in Clinical Nutrition and Metabolic Care2008，，6： | 1 |
| 16 | Restorative Proctocolectomy for Ulcerative Colitis Complicated by Colorectal Cancer显示文摘 | Stephen R. Gorfine M.D. Michael T. Harris M.D. David S. Bub M.D. Joel J. Bauer M.D | 2004 | Diseases of the Colon & Rectum2004，，8： | 1 |
| 17 | A combined comer and edge detector显示文摘 | Harris C Stephens M | 1988 | In Proceedings Alvey Conference1988，92，： | 1 |
| 18 | A Combined Corner and Edge Detector 显示文摘 | Harris C Stephens M | 1988 | Proceedings of the 4th Alvey Vision Conference1988，，： | 1 |
| 19 | A combined corner and edge detector显示文摘 | Harris C G Stephens M Harris C G | 1988 | Proc of Fourth Alvey Vision Conference1988，53，3： | 1 |
| 20 | In Vivo Diagnosis of Plaque Erosion and Calcified Nodule in Patients with Acute Coronary Syndrome by Intravascular Optical Coherence Tomography显示文摘 | Haibo Jia Farhad Abtahian Aaron D. Aguirre Stephen Lee Stanley Chia Harry Lowe Koji Kato Taishi Yonetsu Rocco Vergallo Sining Hu Jinwei Tian Hang Lee Seung-Jung Park Yang-Soo Jang Owen C. Raffel Kyoichi Mizuno Shiro Uemura Tomonori Itoh Tsunekazu Kakuta S | 2013 | Journal of the American College of Cardiology2013，，： | 1 |
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