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| 1 | Nationwide trends and predictors of inpatient mortality in 83884 transjugular intrahepatic portosystemic shunt显示文摘AIM: To evaluate and validate the national trends and predictors of in-patient mortality of transjugular intrahepatic portosystemic shunt(TIPS) in 15 years.METHODS: Using the National Inpatient Sample which is a part of Health Cost and Utilization Project, we identified a discharge-weighted national estimate of 83884 TIPS procedures performed in the United States from 1998 to 2012 using international classification of diseases-9 procedural code 39.1. The demographic, hospital and co-morbility data were analyzed using a multivariant analysis. Using multi-nominal logistic regression analysis, we determined predictive factors related to increases in-hospital mortality. Comorbidity measures are in accordance to the Comorbidity Software designed by the Agency for Healthcare Research and Quality.RESULTS: Overall, 12.3% of patients died during hospitalization with downward trend in-hospitalmortality with the mean length of stay of 10.8 ± 13.1 d. Notable, African American patients(OR = 1.809 vs Caucasian patients, P < 0.001), transferred patients(OR = 1.347 vs non-transferred, P < 0.001), emergency admissions(OR = 3.032 vs elective cases, P < 0.001), patients in the Northeast region(OR = 1.449 vs West, P < 0.001) had significantly higher odds of inhospital mortality. Number of diagnoses and number of procedures showed positive correlations with in-hospital death(OR = 1.249 per one increase in number of procedures). Patients diagnosed with acute respiratory failure(OR = 8.246), acute kidney failure(OR = 4.359), hepatic encephalopathy(OR = 2.217) and esophageal variceal bleeding(OR = 2.187) were at considerably higher odds of in-hospital death compared with ascites(OR = 0.136, P < 0.001). Comorbidity measures with the highest odds of in-hospital death were fluid and electrolyte disorders(OR = 2.823), coagulopathy(OR = 2.016), and lymphoma(OR = 1.842).CONCLUSION: The overall mortality of the TIPS procedure is steadily decreasing, though the length of stay has remained relatively constant. Specific patient ethnicity, location, transfer status, primary diagnosis and comorbidities correlate with increased odds of TIPS in-hospital death. | Edward Wolfgang Lee Andrew Kuei Sammy Saab Ronald W Busuttil Francisco Durazo Steven-Huy Han Mohamed M El-Kabany Justin P Mc Williams Stephen T Kee | 2016 | World Journal of Gastroenterology2016，22，25： | 7 |
| 2 | Failed biliary cannulation: Clinical and technical outcomes after tertiary referral endoscopic retrograde cholangiopancreatography显示文摘AIM: Prospective evaluation of repeat endoscopic retrograde cholangiopancreatography (ERCP) for failed Schutz grade 1 biliary cannulation in a high-volume center. METHODS: Prospective intention-to-treat analysis of patients referred for biliary cannulation following recent unsuccessful ERCP. RESULTS: Fifty-one patients (35 female; mean age: 62.5 years; age range: 40-87 years) with previous failed biliary cannulation were referred for repeat ERCP. The indication for ERCP was primarily choledocholithiasis (45%) or pancreatic malignancy (18%). Successful biliary can- nulation was 100%. The precut needle knife sphincterotomy (NKS) rate was 27.4%. Complications occurred in 3.9% (post-ERCP pancreatitis). An identif iable reason for initial unsuccessful biliary cannulation was present in 55% of cases. Compared to a cohort of 940 nave pa-pilla patients (female 61%; mean age: 59.9 years; age range: 18-94 years) who required sphincterotomy over the same time period, there was no statistical difference in the cannulation success rate (100% vs 98%) or postERCP pancreatitis (3.1% vs 3.9%). Precut NKS use was more frequent (27.4% vs 12.7%) (P = 0.017). CONCLUSION: Referral to a high-volume center following unsuccessful ERCP is associated with high technical success, with a favorable complication rate, compared to routine ERCP procedures. | Michael P Swan Michael J Bourke Stephen J Williams Sina Alexander Alan Moss Rick Hope David Ruppin | 2011 | World Journal of Gastroenterology2011，17，45： | 6 |
| 3 | Stability and preservative effectiveness of treprostinil sodium after dilution in commom intracenous diluents显示文摘 | Kenneth R P William E W Stephen P M | 2003 | Health-System Pharmacy2003，60，9： | 1 |
| 4 | A General Theory of Network Governance:Exchange Conditions and Social Mechanisms 显示文摘 | CANDACE J WILLIAM S H STEPHEN P B | 1997 | The Academy of Management Review1997，22，4： | 1 |
| 5 | Targeting the Cancer Initiating Cell: The Ultimate Target for Cancer Therapy显示文摘 | James A. McCubrey Linda S. Steelman Stephen L. Abrams Negin Misaghian William H. Chappell Jorg Basecke Ferdinando Nicoletti Massimo Libra Giovanni Ligresti Francac Stivala Danijela Maksimovic-Ivanic Sanja Mijatovic Giuseppeo Montalto Melchiorre Cervello P | 2012 | Current Pharmaceutical Design2012，，13： | 1 |
| 6 | Retention ratio and nonequilibriumband- spreading in asymmetrical flow field-flow fractionation显示文摘 | WILLIAMS STEPHEN P | 2015 | Anal Bio- anal Chem2015，407，6： | 1 |
| 7 | MTBE and priority contaminant treatment with high energy electron beam injection显示文摘 | William J C Michael G N Stephen P M | 2002 | Radiation Physics Chem2002，65，： | 1 |
| 8 | A combustion chemistry analysis of carbonate solvents used in Li-ion batteries显示文摘 | STEPHEN J HARRIS A T WILLIAM J P | | 0，，02： | 1 |
| 9 | Understading noncovalent interactions: ligand binding energy and catalytic efficiency from ligand-induced reduction in motion within receptors and enzymes显示文摘 | WILLIAMS D H STEPHENS E O' BREIN D P | 2004 | Angew Chem ( Int Ed Engl )2004，43，48： | 1 |
| 10 | H1N1 2009 influenza virus infection during pregnancy in the USA显示文摘 | Denise J Jamieson Margaret A Honein Sonja A Rasmussen Jennifer L Williams David L Swerdlow Matthew S Biggerstaff Stephen Lindstrom Janice K Louie Cara M Christ Susan R Bohm Vincent P Fonseca Kathleen A Ritger Daniel J Kuhles Paula Eggers Hollianne Bruce H | 2009 | The Lancet2009，，9688： | 1 |
| 11 | Phosphoinositide 3-kinase as drug targets in cancer显示文摘 | STEPHENS L WILLIAMS R HAWKINS P | 2005 | Curr Opin Pharmacol2005，5，4： | 1 |
| 12 | Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys显示文摘 | M Innes Asher Stephen Montefort Bengt Bj?rkstén Christopher KW Lai David P Strachan Stephan K Weiland Hywel Williams | 2006 | The Lancet2006，，9537： | 1 |
| 13 | A Gen- eral Theory of Network Governance: Exchange Conditions and Social Mechanisms 显示文摘 | Candace Jones William S Hesterly Stephen P Borgatti | 1997 | The Academy of Management Review1997，22，4： | 1 |
| 14 | Magnitude and direction of thermal diffusion of colloidal particles measured by thermal field-flow fractionation显示文摘 | Paul M Shiundu Stephen Williams P Calvin Giddings J | 2003 | Journal of Colloid and Interface Science2003，266，： | 1 |
| 15 | Effect of angiotensin receptor blockade and antihypertensive drugs on diastolic function in patients with hypertension and diastolic dysfunction: a randomised trial显示文摘 | Scott D Solomon Rajesh Janardhanan Anil Verma Mikhail Bourgoun William L Daley Das Purkayastha Yves Lacourcière Stephen E Hippler Harold Fields Tasneem Z Naqvi Sharon L Mulvagh J Malcolm O Arnold James D Thomas Michael R Zile Gerard P Aurigemma | 2007 | The Lancet . 2007 (9579)2007，，： | 1 |
| 16 | Influence of accumulation wall and carrier solution composition on lift force in sedimentation/steric field-flow fractionation显示文摘 | Stephen Williams P Myeong Hee Moon Giddings J C | 1996 | Colloids and Surface A: Physicochemcal ang Engineering Aspects1996，113，： | 1 |
| 17 | Study of internal deformation fields in granular materials using 3-D digital speckle X-ray flash photography 显示文摘 | William P G Goldrein Howell T | 2000 | Proc of SPIE-The Int Soc for Opt Eng2000，，： | 1 |
| 18 | Phosphoinositide 3-kinases as drug targets in cancer 显示文摘 | Stephens L Williams R Hawkins P | 2005 | Curr Opin Pharmacol2005，5，4： | 1 |
| 19 | Study of internal deformation fields in granular materials using 3-D digital speckle X-ray flash photography显示文摘 | STEPHEN G G WILLIAM P G | 2000 | Proc of SPIE the Int Soc for Opt Eng2000，，： | 1 |
| 20 | Magnitude and direction of thermal diffusion of colloidal particles measured by thermal field-flow fractionation显示文摘 | Shiundu Paul M Williams P Stephen Giddings B Calvin | 2003 | Journal of Colloid and Interface Science2003，266，： | 1 |
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