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| 1 | Borderline Resectable Pancreatic Cancer: Need for Standardization and Methods for Optimal Clinical Trial Design显示文摘 | Matthew H. G. Katz Robert Marsh Joseph M. Herman Qian Shi Eric Collison Alan P. Venook Hedy L. Kindler Steven R. Alberts Philip Philip Andrew M. Lowy Peter W. T. Pisters Mitchell C. Posner Jordan D. Berlin Syed A. Ahmad | 2013 | Annals of Surgical Oncology2013，，8： | 4 |
| 2 | Malaria over-diagnosis in Cameroon:diagnostic accuracy of Fluorescence and Staining Technologies(FAST)Malaria Stain and LED microscopy versus Giemsa and bright field microscopy validated by polymerase chain reaction显示文摘Background:Malaria is a major world health issue and its continued burden is due,in part,to difficulties in the diagnosis of the illness.The World Health Organization recommends confirmatory testing using microscopy-based techniques or rapid diagnostic tests(RDT)for all cases of suspected malaria.In regions where Plasmodium species are indigenous,there are multiple etiologies of fever leading to misdiagnoses,especially in populations where HIV is prevalent and children.To determine the frequency of malaria infection in febrile patients over an 8-month period at the Regional Hospital in Bamenda,Cameroon,we evaluated the clinical efficacy of the Flourescence and Staining Technology(FAST)Malaria stain and ParaLens AdvanceTM microscopy system(FM)and compared it with conventional bright field microscopy and Giemsa stain(GS).Methods:Peripheral blood samples from 522 patients with a clinical diagnosis of“suspected malaria”were evaluated using GS and FM methods.A nested PCR assay was the gold standard to compare the two methods.PCR positivity,sensitivity,specificity,positive predictive value(PPV),and negative predictive value(NPV)were determined.Results:Four hundred ninety nine samples were included in the final analysis.Of these,30 were positive via PCR(6.01%)with a mean PPV of 19.62%and 27.99%for GS and FM,respectively.The mean NPV was 95.01%and 95.28%for GS and FM,respectively.Sensitivity was 26.67%in both groups and specificity was 92.78%and 96.21%for GS and FM,respectively.An increased level of diagnostic discrepancy was observed between technicians based upon skill level using GS,which was not seen with FM.Conclusions:The frequency of malarial infections confirmed via PCR among patients presenting with fever and other symptoms of malaria was dramatically lower than that anticipated based upon physicians’clinical suspicions.A correlation between technician skill and accuracy of malaria diagnosis using GS was observed that was less pronounced using FM.Additionally,FM increased the specificity and improved the PPV,suggesting this relatively low cost approach could be useful in resource-limited environments.Anecdotally,physicians were reluctant to not treat all patients symptomatically before results were known and in spite of a negative microscopic diagnosis,highlighting the need for further physician education to avoid this practice of overtreatment.A larger study in an area with a known high prevalence is being planned to compare the two microscopy methods against available RDTs. | Sean M.Parsel Steven A.Gustafson Edward Friedlander Alexander A.Shnyra Aderosoye J.Adegbulu Ying Liu Nicole M.Parrish Syed A.Jamal Eve Lofthus Leo Ayuk Charles Awasom Carolyn J.Henry Carole P.McArthur | 2017 | Infectious Diseases of Poverty2017，6，1： | 2 |
| 3 | Loss of cardiac sympathetic neurotransmitters in heart failure and NE in fusion is associated with reduced NGF显示文摘 | Qin F Vulapalli RS Stevens SY | 2002 | Am J Physiol Heart Circ Physiol2002，282，1： | 1 |
| 4 | Hepatitis B or C virus serology as a prognostic factor in patients with hepatocellular carcinoma显示文摘 | Syed A. Ahmad M.D. Malcolm M. Bilimoria M.D. Xuemei Wang Francesco Izzo M.D. Paolo Delrio M.D. Paolo Marra M.D. Treneth P. Baker M.D. Geoff A. Porter M.D. Lee M. Ellis M.D. Jean N. Vauthey M.D. Sundar Dhamotharan M.D. Steven A. Curley M.D | 2001 | Journal of Gastrointestinal Surgery2001，，5： | 1 |
| 5 | Loss of cardiac sympathetic eurotrasmitters in heart failure and NE infusion is associated with reduced NGF显示文摘 | Qin FZ Vulapalli RS Stevens SY | 2002 | Am J Physiol Heart Circ Physiol2002，282，： | 1 |
| 6 | Prevalence of CKD andcomorbid illness in elderly patients in the United States:results from the Kidney Early Evaluation Program(KEEP)显示文摘 | Stevens LA Li SY Wang CC | 2010 | Am J Kidney Dis2010，55，： | 1 |
| 7 | Renin-angiotensin system inhibition on noradrenergic nerve terminal function in pacing-induced heart failure显示文摘 | Kawai H Stevens SY Liang CS | 2000 | Am J Physiol Heart Circ Physiol2000，279，： | 1 |
| 8 | Treatment of atlantoaxial instability in pediatric patients 显示文摘 | Rahimi SY Stevens EA Yeh D J | 2003 | Neurosurg Focus2003，15，6： | 1 |
| 9 | Loss of cardiac sym- pathetic neurotransmitters in heart failure and NE infusion is associated with reduced NGF 显示文摘 | Qin F Vulapalli RS Stevens SY | 2002 | Am J Physiol Heart Circ Physiol2002，282，1： | 1 |
| 10 | Alterations in T lymphocyte activity following chemical sympathectomy in young and old Fischer 344 rats显示文摘 | Madden KS Stevens SY Felten DL | 2000 | J Neuroimmunol2000，103，2： | 1 |
| 11 | Altered perception of floaters in dementia causing selfinflicted injuries显示文摘Dear Editor,A 74 years old male patient with history of Parkinson disease and vascular dementia presented to the eye clinic with his wife,who is his primary caregiver.The patient reported a multiple year history of complaining of'flies'around his head,which were a source of considerable agitation.He was so bothered by constantly seeing these flies that he carried a custom flyswatter with him(Figure 1)at all times. | Will Griffeth Steven Kane Syed Khurshid Gibran | 2017 | International Journal of Ophthalmology(English edition)2017，10，7： | 1 |
| 12 | Screening for pancreatic neoplasia in high-risk individuals: an EUS-based approach显示文摘 | Marcia Irene Canto Michael Goggins Charles J. Yeo Constance Griffin Jennifer E. Axilbund Kieran Brune Syed Z. Ali Sanjay Jagannath Gloria M. Petersen Elliot K. Fishman Steven Piantadosi Francis M. Giardiello Ralph H. Hruban | 2004 | Clinical Gastroenterology and Hepatology2004，，7： | 1 |
| 13 | Increased Mortality Associated with EMS Transport of Gunshot Wound Victims When Compared to Private Vehicle Transport显示文摘 | Syed Nabeel Zafar Adil H. Haider Kent A. Stevens Nik Ray-Mazumder Mehreen T. Kisat Eric B. Schneider Albert Chi Samuel M Galvagno Jr Edward E. Cornwell David T. Efron Elliott R. Haut | 2014 | Injury2014，，： | 1 |
| 14 | Hemodynamic and pulmonary changes after drainage of significant pleural effusions in critically ill, mechanically ventilated surgical patients 显示文摘 | Syed H Ahmed Steven P Ouzounian Stephen DiRusso | 2004 | J Trauma Injury Infect Crit Care2004，57，6： | 1 |
| 15 | Herpes Zoster Vaccine and the Incidence of Recurrent Herpes Zoster in an Immunocompetent Elderly Population显示文摘 | Hung Fu Tseng Margaret Chi Ning Smith Stephen M. Marcy Lina S. Sy Steven J. Jacobsen | 2012 | Journal of Infectious Diseases2012，，2： | 1 |
| 16 | Loss of cardiac sympathetic neurotransmitters in heart failure and NE infusion is associated with reduced NGF 显示文摘 | Qin F Vulapalli RS Stevens SY | 2002 | Am J Physiol Heart Circ Physiol2002，282，1： | 1 |
| 17 | Sustained Ocular Delivery of Fluocinolone Acetonide by an Intravitreal Insert显示文摘 | Peter A. Campochiaro Gulnar Hafiz Syed Mahmood Shah Steven Bloom David M. Brown Miguel Busquets Thomas Ciulla Leonard Feiner Nelson Sabates Kathleen Billman Barry Kapik Ken Green Frances Kane | 2010 | Ophthalmology2010，，7： | 1 |
| 18 | Loss of cardiac sympathetic neurotransmitters in heart failure and NE infusion is associated with reduced NGF显示文摘 | Qin F Vulapalli RS Stevens SY | 2002 | Am J Physiol Heart Circ Physiol2002，282，1： | 1 |
| 19 | Combined Injuries of the Pelvis and Acetabulum: Nature of a Devastating Dyad显示文摘 | Takashi Suzuki Wade R Smith David J Hak Philip F Stahel Andrea J Baron Syed A Gillani Steven J Morgan | 2010 | Journal of Orthopaedic Trauma2010，，5： | 1 |
| 20 | A meta-analysis of 1-year outcomes of transcatheter versus surgical aortic valve replacement in low-risk patients with severe aortic stenosis显示文摘Background Transcatheter aortic valve replacement(TAVR)for the treatment symptomatic severe aortic stenosis(AS)is indicated in patients with intermediate or higher surgical risk.Latest trials showed TAVR,and surgical aortic valve replacement(SAVR)perform similarly at 1-year for the composite outcomes of mortality,stroke and rehospitalization.We performed a comprehensive meta-analysis to compare individual outcomes at 1-year for TAVR compared to SAVR in low-risk patients.Methods Pub Med,Embase,and Cochrane central were searched for all the randomized controlled trials(RCTs)that reported 1-year comparative outcomes of TAVR and surgical aortic valve replacement(SAVR).Our conclusions are based upon the random-effects model using Der Simonian-Laird estimator.Results Data from 4 trials and 2887 randomized patients showed that TAVR had lower rates of all-cause mortality,cardiovascular mortality,and atrial fibrillation compared to SAVR at 1-year follow-up(P<0.05 for all).Also,TAVR was also associated with a significantly higher risk of permanent pacemaker implantation and moderate-severe paravalvular leak(P<0.05).Conclusions The latest randomised trial data demonstrates that in short-term,TAVR is safe and effective in reducing all-cause mortality or stroke.Longer follow-up of RCTs is needed to determine the durability of clinical benefits in TAVR over SAVR in low-risk patients. | Aaqib H Malik Syed Zaid Hasan Ahmad Joshua Goldberg Tanya Dutta Cenap Undemir Martin Cohen Wilbert S Aronow Steven L Lansman | 2020 | Journal of Geriatric Cardiology2020，17，1： | 0 |
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