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| 1 | 正、负性情绪的跨文化心理测量:PANAS维度结构检验显示文摘对中国大学生 (N =2 0 1 )和美国大学生 (N =32 1 )进行PANAS测评 ,以检验该量表中、英文版的因素效度。探索性因素分析会聚性地验证了该量表的PA和NA两维度结构具有跨文化一致性 ,中、英文量表两因子的累积方差贡献率分别为 51 .31 %和 44 .2 5 % ,接近Watson等的研究结果。然而研究结果也显示测项偏差问题 ,因此中文量表的PA分量表的测项组成不等同于原量表。中、英文量表的PA与NA分量表同样具有较高内在一致性信度 。 | 张卫东 刁静 Constance J.Schick | 2004 | 心理科学2004，27，1： | 114 |
| 2 | 酵母培养物对斑点叉尾鮰幼鱼生长性能的影响显示文摘以斑点叉尾鮰为对象,研究饲料中添加不同比例的酵母培养物[达农威水产益康(DVAQTM)]对其幼鱼成活、生长和饲料系数的影响。基础饲料蛋白含量为32%,赖氨酸含量为需要量的85%(斑点叉尾鮰赖氨酸在饲料蛋白质中的适宜含量5.1%),其余必需氨基酸均满足其需要量,分别向基础饲料中添加酵母培养物0.03%0、.06%和0.12%,且基础饲料中减少一定量的玉米,制成试验饲料,进行为期12周的生长试验。试验在水族箱(75 L)中进行,每个处理设4个重复,每个重复放养10尾鮰幼鱼(平均体重为4.5 g)。研究结果表明0,.06%和0.12%添加组鮰成活率均为100%,略高于对照组(97%)。0.06%添加组鮰幼鱼增重率较对照组平均提高19%,饲料系数降低13%。0.12%添加组较对照组增重率平均提高22%,饲料系数降低15%。因此,饲料中添加酵母培养物可提高斑点叉尾鮰幼鱼的生长性能。 | H.Randall Robinette Constance Young 孟繁伊 | 2011 | 饲料工业2011，32，6： | 10 |
| 3 | 酵母培养物对饲喂高纤维饲料池塘养殖鮰鱼生产性能的影响显示文摘试验以池塘养殖斑点叉尾鮰为对象,研究在高纤维饲料中添加酵母培养物(达农威水产益康DVAQUATM)对其成活率、生长和饲料系数的影响。饲料蛋白含量为32%。低纤维饲料中的粗纤维含量为4%,高纤维饲料中的粗纤维含量为1O%。试验在12个面积为0.05~0.07公顷的池塘中进行,试验鱼放养密度为13,590条/公顷。试验共设5个处理组,分别为低纤维饲料组、高纤维饲料组和高纤维饲料+酵母培养物组。每个处理组设4个重复,养殖周期为20周。研究结果表明,虽然各处理组之间在生产性能方面差异不显著(P〉0.05),但饲喂酵母培养物的处理组在成活率、鱼体增重、每平方米产量和饲料系数方面均表现出一定的优势。与饲喂含高纤维和低纤维饲料的处理组相比较,添加酵母培养物使得鮰鱼体重分别增加了10.6%和18.6%,单位面积产量分别提高了15.6%和14.8%,饲料转化效率分别提高了5.2%和20.O%。因此,饲料中添加酵母培养物可提高斑点叉尾鮰的生长性能。 | 孟繁伊 H.Randall Robinette Constance Young | 2013 | 饲料与畜牧(新饲料)2013，，9： | 6 |
| 4 | UFMylation of RPL26 links translocation-associated quality control to endoplasmic reticulum protein homeostasis显示文摘Protein biogenesis at the endoplasmic reticulum(ER)in eukaryotic cells is monitored by a protein quality control system named ER-associated protein degradation(ERAD).While there has been substantial progress in understanding how ERAD eliminates defective polypeptides generated from erroneous folding,how cells remove nascent chains stalled in the translocon during co-translational protein insertion into the ER is unclear.Here we show that ribosome stalling during protein translocation induces the attachment of UFM1,a ubiquitin-like modifier,to two conserved lysine residues near the COOH-terminus of the 60S ribosomal subunit RPL26(uL24)at the ER.Strikingly,RPL26 UFMylation enables the degradation of stalled nascent chains,but unlike ERAD or previously established cytosolic ribosome-associated quality control(RQC),which uses proteasome to degrade their client proteins,ribosome UFMylation promotes the targeting of a translocation-arrested ER protein to lysosomes for degradation.RPL26 UFMylation is upregulated during erythroid differentiation to cope with increased secretory flow,and compromising UFMylation impairs protein secretion,and ultimately hemoglobin production.We propose that in metazoan,co-translational protein translocation into the ER is safeguarded by a UFMylation-dependent protein quality control mechanism,which when impaired causes anemia in mice and abnormal neuronal development in humans. | Lihui Wang Yue Xu Heather Rogers Layla Saidi Constance Tom Noguchi Honglin Li Jonathan Wilson Yewdell Nicholas Raymond Guydosh Yihong Ye | 2020 | Cell Research2020，30，1： | 5 |
| 5 | MELD score,insulin-like growth factor 1 and cytokines on bone density in end-stage liver disease显示文摘AIM:To determine the contributions of insulin-like growth factor 1 (IGF-1),cytokines and liver disease severity to bone mineral density in patients pre-transplantation.METHODS:Serum IGF-1,tumor necrosis factor-α (TNFα) and interleukin 6 (IL-6) were measured and the Model for End-Stage Liver Disease (MELD) score calculated in 121 adult patients referred to a single centre for liver transplantation.Bone mineral density (BMD) of the lumbar spine and femoral neck were assessed via dual energy X-ray absorptiometry.Demographics,liver disease etiology,medication use and relevant biochemistry were recorded.RESULTS:A total of 117 subjects were included,with low BMD seen in 68.6%,irrespective of disease etiol-ogy.In multivariable analysis,low body mass index (BMI),increased bone turnover and low IGF-1 were independent predictors of low spinal bone density.At the hip,BMI,IGF-1 and vitamin D status were predictive.Despite prevalent elevations of TNFα and IL-6,levels did not correlate with degree of bone loss.The MELD score failed to predict low BMD in this pre-transplant population.CONCLUSION:Osteopenia/osteoporosis is common in advanced liver disease.Low serum IGF-1 is weakly predictive but serum cytokine and MELD score fail to predict the severity of bone disease. | Rebecca Mitchell Jill McDermid Mang M Ma Constance L Chik | 2011 | World Journal of Hepatology2011，3，6： | 5 |
| 6 | Erythropoietin modulates bone marrow stromal cell differentiation显示文摘Erythropoietin is essential for bone marrow erythropoiesis and erythropoietin receptor on non-erythroid cells including bone marrow stromal cells suggests systemic effects of erythropoietin. Tg6 mice with chronic erythropoietin overexpression have a high hematocrit, reduced trabecular and cortical bone and bone marrow adipocytes, and decreased bone morphogenic protein 2 driven ectopic bone and adipocyte formation. Erythropoietin treatment(1 200 IU·kg–1) for 10 days similarly exhibit increased hematocrit,reduced bone and bone marrow adipocytes without increased osteoclasts, and reduced bone morphogenic protein signaling in the bone marrow. Interestingly, endogenous erythropoietin is required for normal differentiation of bone marrow stromal cells to osteoblasts and bone marrow adipocytes.ΔEpoR_E mice with erythroid restricted erythropoietin receptor exhibit reduced trabecular bone, increased bone marrow adipocytes, and decreased bone morphogenic protein 2 ectopic bone formation. Erythropoietin treated ΔEpoR_E mice achieved hematocrit similar to wild-type mice without reduced bone, suggesting that bone reduction with erythropoietin treatment is associated with non-erythropoietic erythropoietin response. Bone marrow stromal cells from wild-type,Tg6, and ΔEpoR_E-mice were transplanted into immunodeficient mice to assess development into a bone/marrow organ. Like endogenous bone formation, Tg6 bone marrow cells exhibited reduced differentiation to bone and adipocytes indicating that high erythropoietin inhibits osteogenesis and adipogenesis, while ΔEpoR_E bone marrow cells formed ectopic bones with reduced trabecular regions and increased adipocytes, indicating that loss of erythropoietin signaling favors adipogenesis at the expense of osteogenesis. In summary, endogenous erythropoietin signaling regulates bone marrow stromal cell fate and aberrant erythropoietin levels result in their impaired differentiation. | Sukanya Suresh Luis Fernandez de Castro Soumyadeep Dey Pamela G. Robey Constance Tom Noguchi | 2019 | Bone Research2019，7，3： | 5 |
| 7 | Corrigendum to“Site directed mutagenesis as a precision tool to enable synthetic biology with engineered modular polyketide synthases”[Synth Syst Biotechnol 5(2)(2020)62–80]显示文摘The authors regret that following the publication of the original article,the authors noticed that some of the structures in Fig.10 were incorrect.Below is the corrected figure. | Erin E.Drufva Elijah G.Hix Constance B.Bailey | 2020 | Synthetic and Systems Biotechnology2020，5，4： | 4 |
| 8 | Secretion of Angiogenic and Antiapoptotic Factors by Human Adipose Stromal Cells显示文摘 | Jalees Rehman Dmitry Traktuev Jingling Li Stephanie Merfeld-Clauss Constance J. Temm-Grove Jason E. Bovenkerk Carrie L. Pell Brian H. Johnstone Robert V. Considine Keith L. March | 2004 | Circulation: Journal of the American Heart Association2004，，10： | 4 |
| 9 | 研究型馆藏资源的云图书馆计划(摘要)——在大规模数字图书馆环境下管理印本资源显示文摘云图书馆计划(Cloud Library project)是由OCLC研究中心、Hathi Trust数字图书馆、纽约大学Elmer Holmes Bobst图书馆、研究型馆藏获取和保存联盟(the Research Collections Access&Preservation Consortium,ReCAP)四方联合策划和实施的项目,得到安德鲁梅隆·基金会的赞助,旨在研究大学图书馆中利用率低的印本图书实施外包管理的可行性。外包提供者是共享服务提供者,包括大型印本和数字资源仓储。 | Constance Malpas(著) 宋丹辉(编译) | 2011 | 图书情报工作动态2011，，3： | 4 |
| 10 | Dominance network structure across reproductive contexts in the cooperatively breeding cichlid fish Neolamprologus pulcher显示文摘 | Cody J. DEY Q.Y. Joanne TAN Constance M. O'CONNOR Adam R. REDDON J. Ryan CALDWELL Sigal BALSHINE | 2015 | Current Zoology2015，61，1： | 4 |
| 11 | Engineered polyketides:Synergy between protein and host level engineering显示文摘Metabolic engineering efforts toward rewiring metabolism of cells to produce new compounds often require the utilization of non-native enzymatic machinery that is capable of producing a broad range of chemical functionalities.Polyketides encompass one of the largest classes of chemically diverse natural products.With thousands of known polyketides,modular polyketide synthases(PKSs)share a particularly attractive biosynthetic logic for generating chemical diversity.The engineering of modular PKSs could open access to the deliberate production of both existing and novel compounds.In this review,we discuss PKS engineering efforts applied at both the protein and cellular level for the generation of a diverse range of chemical structures,and we examine future applications of PKSs in the production of medicines,fuels and other industrially relevant chemicals. | Jesus F.Barajas Jacquelyn M.Blake-Hedges Constance B.Bailey Samuel Curran Jay.D.Keasling | 2017 | Synthetic and Systems Biotechnology2017，2，3： | 3 |
| 12 | Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States显示文摘 | Constance E. Ruhl James E. Everhart | 2003 | Gastroenterology2003，，1： | 2 |
| 13 | Emissions of mercury, trace elements, and fine particles from stationary combustion sources显示文摘 | Constance L Senior Joseph J Helble Adel F Sarofim | 2000 | Fuel Processing Technology2000，，： | 2 |
| 14 | The comparative efficacy of ezetimibe added to atorvastatin 10 mg versus uptitration to atorvastatin 40 mg in subgroups of patients aged 65 to 74 years or greater than or equal to 75 years显示文摘有年龄的背景冠的心疾病(CHD ) 风险增加;然而类脂化合物阴沉的治疗是显著地在病人的 under-utilized > 65 年。目的是评估安全,在更老的病人的类脂化合物阴沉的治疗的功效与 atorvastatin 对待 10 mg + ezetimibe 10 mg (EZ/Atorva ) 对增加 atorvastatin 剂量到 40 mg。方法病人有动脉粥样硬化患者的 65 年脉管的疾病(LDL-C 1.81 mmol/L ) 或在为冠的心的高风险,疾病(LDL-C 2.59 mmol/L ) 为 12 wk 对 uptitration 被使随机化到 EZ/Atorva 到为 6 wk 的 20 mg 由 atorvastatin 跟随了的 atorvastatin 为 6 wk 的 40 mg。在完成 prespecified LDL-C 层次的 LDL-C 和另外的类脂化合物参数和百分比病人的百分比变化在 12 wk 以后被估计。结果 EZ/Atorva 在病人在大多数类脂化合物参数对 atorvastatin 的 uptitration 生产了更大的减小 75 年(n = 228 ) ,与病人通常一致 6574 年(n = 812 ) 。更多的病人在 6 wk 并且在病人在两个年龄组与联合治疗对 monotherapy 完成了 LDL-C 目标在 12 wk 的 75 年。在 12 wk,更多的病人 75 年与 monotherapy 对联合治疗完成了 LDL-C 目标。EZ/Atorva 在大多数类脂化合物生产了更有利的改进对加倍或 quadrupling 在病人的 atorvastatin 剂量 75 年,与在病人的调查结果通常一致 6574 年。我们的结果扩大了证明 ezetimibe 增加了 statin 的以前的调查结果的结论为在病人改进类脂化合物侧面提供了一种通常容忍得好的治疗学的选择 65 ~ 74 年和 75 岁。 | Ori Ben-Yehuda Nanette K. Wenger Christian Constance Franklin Zieve Mary E. Hanson Jian-Xin Lin Arvind K. Shah Charlotte Jones-Burton Andrew M. Tershakovec | 2011 | Journal of Geriatric Cardiology2011，8，1： | 2 |
| 15 | Elevated Serum Alanine Aminotransferase and γ-Glutamyltransferase and Mortality in the United States Population显示文摘 | Constance E. Ruhl James E. Everhart | 2009 | Gastroenterology2009，，2： | 2 |
| 16 | 自主:皮亚杰的教育目标显示文摘 | Kamii Constance 张先恰 | 1995 | 教育科学研究1995，，2： | 2 |
| 17 | Frequent Detection of Pancreatic Lesions in Asymptomatic High-Risk Individuals显示文摘 | Marcia Irene Canto Ralph H. Hruban Elliot K. Fishman Ihab R. Kamel Richard Schulick Zhe Zhang Mark Topazian Naoki Takahashi Joel Fletcher Gloria Petersen Alison P. Klein Jennifer Axilbund Constance Griffin Sapna Syngal John R. Saltzman Koenraad J. Mortele | 2012 | Gastroenterology2012，，4： | 2 |
| 18 | Expression of epidermal growth factor receptor in esophageal and esophagogastric junction adenocarcinomas显示文摘 | Kim L.Wang Tsung‐TehWu In SeonChoi HuaminWang ErikaResetkova Arlene M.Correa Wayne L.Hofstetter Stephen G.Swisher Jaffer A.Ajani AsifRashid Constance T.Albarracin | 2007 | Cancer2007，，4： | 2 |
| 19 | Secretion of Angiogenic and Antiapoptotic Factors by Human Adipose Stromal Cells显示文摘 | Jalees Rehman Dmitry Traktuev Jingling Li Stephanie Merfeld-Clauss Constance J. Temm-Grove Jason E. Bovenkerk Carrie L. Pell Brian H. Johnstone Robert V. Considine Keith L. March | 2004 | Circulation: Journal of the American Heart Association2004，，10： | 2 |
| 20 | Pilot testing of CO_(2) capture from a coal-fired power plant-Part 2:Results from 1-MWe pilot tests显示文摘Using a 1-MWe slipstream pilot plant,solid-sorbent-based post-combustion CO_(2) capture was tested at a coal-fired power plant.Results from pilot testing were used to develop a preliminary full-scale commercial design.The sorbent selected for pilot-scale evaluation during this project consisted of an ion-exchange resin that incorporated amines covalently bonded to the substrate.A unique temperature-swing-absorption(TSA)process was developed that incorporated a three-stage fluidized-bed adsorber integrated with a single-stage fluidized-bed regenerator.Overall,following start-up and commissioning challenges that are often associated with first-of-a-kind pilots,the pilot plant operated as designed and expected,with a few key exceptions.The two primary exceptions were associated with:(i)handling characteristics of the sorbent,which were sufficiently different at operating temperature than at ambient temperature when design specifications were established with lab-scale testing;and(ii)CO_(2) adsorption in the transport line between the regenerator and adsorber that preloaded the sorbent with CO_(2) prior to entering the adsorber.Results from the pilot programme demonstrate that solid-sorbent-based post-combustion capture can be utilized to achieve 90%CO_(2) capture from coal-fired power plants. | Sharon Sjostrom Constance Senior | 2020 | Clean Energy2020，4，1： | 2 |
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