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181篇 您的检索式:作者名="Sun Lijuan"
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1Erianin,a novel dibenzyl compound in Dendrobium extract,inhibits lung cancer cell growth and migration via calcium/calmodulin-dependent ferroptosis显示文摘Ferroptosis,a novel form of programmed cell death,is characterized by iron-dependent lipid peroxidation and has been shown to be involved in multiple diseases,including cancer.Stimulating ferroptosis in cancer cells may be a potential strategy for cancer therapy.Therefore,ferroptosis-inducing drugs are attracting more attention for cancer treatment.Here,we showed that erianin,a natural product isolated from Dendrobium chrysotoxum Lindl,exerted its anticancer activity by inducing cell death and inhibiting cell migration in lung cancer cells.Subsequently,we demonstrated for the first time that erianin induced ferroptotic cell death in lung cancer cells,which was accompanied by ROS accumulation,lipid peroxidation,and GSH depletion.The ferroptosis inhibitors Fer-1 and Lip-1 but not Z-VAD-FMK,CQ,or necrostatin-1 rescued erianin-induced cell death,indicating that ferroptosis contributed to erianin-induced cell death.Furthermore,we demonstrated that Ca^(2+)/CaM signaling was a critical mediator of erianin-induced ferroptosis and that blockade of this signaling significantly rescued cell death induced by erianin treatment by suppressing ferroptosis.Taken together,our data suggest that the natural product erianin exerts its anticancer effects by inducing Ca^(2+)/CaMdependent ferroptosis and inhibiting cell migration,and erianin will hopefully serve as a prospective compound for lung cancer treatment.Peng Chen Qibiao Wu Jiao Feng Lili Yan Yitian Sun Shuiping Liu Yu Xiang Mingming Zhang Ting Pan Xiaying Chen Ting Duan Lijuan Zhai Bingtao Zhai Wengang Wang Ruonan Zhang Bi Chen Xuemeng Han Yicong Li Liuxi Chen Ying Liu Xingxing Huang Ting Jin Wenzheng Zhang Hong Luo Xiaohui Chen Yongqiang Li Qiujie Li Guohua Li Qin Zhang Lvjia Zhuo Zuyi Yang Huifen Tang Tian Xie Xiaoping Ouyang Xinbing Sui 2020Signal Transduction and Targeted Therapy2020,5,1:42
2Insights into the role of gut microbiota in obesity: pathogenesis, mechanisms, and therapeutic perspectives显示文摘Lijuan Sun Lanjing Ma Yubo Ma Faming Zhang Changhai Zhao Yongzhan Nie 2018Protein & Cell2018,9,5:29
3Deep carbon cycles constrained by a large-scale mantle Mg isotope anomaly in eastern China显示文摘Although deep carbon recycling plays an important role in the atmospheric CO_2 budget and climate changes through geological time,the precise mechanisms remain poorly understood.Since recycled sedimentary carbonate through plate subduction is the main light-δ^(26)Mg reservoir within deep-Earth,Mg isotope variation in mantle-derived melts provides a novel perspective when investigating deep carbon cycling.Here,we show that the Late Cretaceous and Cenozoic continental basalts from 13 regions covering the whole of eastern China have low δ^(26)Mg isotopic compositions,while the Early Cretaceous basalts from the same area and the island arc basalts from circum-Paciic subduction zones have mantle-like or heavy Mg isotopic characteristics.hus,a large-scale mantle low δ^(26)Mg anomaly in eastern China has been delineated,suggesting the contribution of sedimentary carbonates recycled into the upper mantle,but limited into the lower mantle.his large-scale spatial and temporal variation of Mg isotopes in the mantle places severe constraints on deep carbon recycling via oceanic subduction.Shu-Guang Li Wei Yang Shah Ke Xunan Meng Hengci Tian Lijuan Xu Yongsheng He Jian Huang Xuan-Ce Wang Qunke Xia Weidong Sun Xiaoyong Yang Zhong-Yuan Ren Haiquan Wei Yongsheng Liu Fancong Meng Jun Yan 2017National Science Review2017,4,1:23
4The recommendations of Chinese Parkinson’s disease and movement disorder society consensus on therapeutic management of Parkinson’s disease显示文摘Background:Parkinson’s disease(PD)is a chronic,progressive and debilitating disease,which affects over 2.5 million people in China.PD is characterized clinically by resting tremor,muscular rigidity,bradykinesia and postural instability.As the disease progresses,additional complications can arise such as non-motor and neurobehavioral symptoms.Pharmacological treatment and surgical intervention for PD have been implemented in China.Until 10 years ago,there was lack of standardization for the management of PD in different regions and among different physicians,leading to different treatment levels in different regions and different physicians.Since then,the Chinese Parkinson’s Disease and Movement Disorder Society have published three versions of guidelines for the management of PD in China,in 2006,2009 and 2014,respectively.Correspondingly,the overall level of treatment for PD in China improved.Objectives:To update the treatment guidelines based on current foreign and domestic practice guidelines and clinical evidence,and to improve the treatment options available to physicians in the management of PD.Summary:A variety of treatment recommendations in the treatment guidelines have been proposed,including physical activity and disease-modifying medication,which should be initiated at the early-stage of the disease.The principles of dosage titration should be followed to avoid acute adverse reactions to the drugs,to achieve a satisfactory clinical effect with a low dose and to reduce the incidence of long-term motor complications.Moreover,different treatment strategies should be considered at different stages of the disease.Importantly,treatment guidelines and personalized treatments should be valued equally.A set of treatment recommendations has been developed to assist physicians to improve and optimize clinical outcomes for patients with PD in China.Shengdi Chen Piu Chan Shenggang Sun Haibo Chen Baorong Zhang Weidong Le Chunfeng Liu Guoguang Peng Beisha Tang Lijuan Wang Yan Cheng Ming Shao Zhenguo Liu Zhenfu Wang Xiaochun Chen Mingwei Wang Xinhua Wan Huifang Shang Yiming Liu Pingyi Xu Jian Wang Tao Feng Xianwen Chen Xingyue Hu Anmu Xie Qin Xiao 2016Translational Neurodegeneration2016,5,1:23
5Grenvillian orogeny in the Southern Cathaysia Block:Constraints from U-Pb ages and Lu-Hf isotopes in zircon from metamorphic basement显示文摘Metamorphic basement rocks in the Cathaysia Block are composed mainly of meta-sediments with different ages. New zircon U-Pb geochronological results from the meta-sedimentary rocks exposed in the Zengcheng and Hezi areas, southern Cathaysia Block, show that they consist dominantly of early Neoproterozoic (1.0―0.9 Ga) materials with minor Paleo- to Mesoproterozoic and late Neoproterozoic (0.8―0.6 Ga) components, suggesting that the detritus mostly come from a Grenvillian orogen. The youngest detrital zircon ages place a constraint on the deposition time of these sediments in Late Neoproterozoic. Zircon Hf isotopic compositions indicate that the Grenvillian zircons were derived from the reworking of Mesoproterozoic arc magmatic rocks and Paleoproterozoic continental crust, implying an arc-continent collisional setting. Single-peak age spectra and the presence of abundant euhedral Grenvillian zircons suggest that the sedimentary provenance is not far away from the sample location. Thus, the Grenvillian orogen probably preexisted along the southern margin of the Cathaysia Block, or very close to the south. Similarity in the ages of Grenvillian orogeny and the influence of the assembly of Gondwana in South China with India and East Antarctic are discussed, with suggestion that South China was more likely linked with the India-East Antarctica continents in Early Neoproterozoic rather than between western Laurentia and eastern Australia.WANG LiJuan YU JinHai S.Y. O'REILLY W.L. GRIFFIN SUN Tao WEI ZhenYang JIANG ShaoYong SHU LiangShu 2008Chinese Science Bulletin2008,53,19:21
6A Review of Seasonal Climate Prediction Research in China显示文摘The ultimate goal of climate research is to produce climate predictions on various time scales. In China, efforts to predict the climate started in the 1930 s. Experimental operational climate forecasts have been performed since the late 1950 s,based on historical analog circulation patterns. However, due to the inherent complexity of climate variability, the forecasts produced at that time were fairly inaccurate. Only from the late 1980 s has seasonal climate prediction experienced substantial progress, when the Tropical Ocean and Global Atmosphere project of the World Climate Research program(WCRP) was launched. This paper, following a brief description of the history of seasonal climate prediction research, provides an overview of these studies in China. Processes and factors associated with the climate variability and predictability are discussed based on the literature published by Chinese scientists. These studies in China mirror aspects of the climate research effort made in other parts of the world over the past several decades, and are particularly associated with monsoon research in East Asia. As the climate warms, climate extremes, their frequency, and intensity are projected to change, with a large possibility that they will increase. Thus, seasonal climate prediction is even more important for China in order to effectively mitigate disasters produced by climate extremes, such as frequent floods, droughts, and the heavy frozen rain events of South China.WANG Huijun FAN Ke SUN Jianqi LI Shuanglin LIN Zhaohui ZHOU Guangqing CHEN Lijuan LANG Xianmei LI Fang ZHU Yali CHEN Hong ZHENG Fei 2015Advances in Atmospheric Sciences2015,32,2:20
7Calycosin-7-O-β-D-glucopyranoside stimulates osteoblast differentiation through regulating the BMP/WNT signaling pathways显示文摘The iso fl avone calycosin-7-O-β-D-glucopyranoside(CG) is a principal constituent of Astragalus membranaceus(AR) and has been reported to inhibit osteoclast development in vitro and bone loss in vivo. The aim of this study was to investigate the osteogenic effects of CG and its underlying mechanism in ST2 cells. The results show that exposure of cells to CG in osteogenic differentiation medium increases ALP activity, osteocalcin(Ocal) m RNA expression and the osteoblastic mineralization process. Mechanistically, CG treatment increased the expression of bone morphogenetic protein 2(BMP-2), p-Smad 1/5/8, β-catenin and Runx2, all of which are regulators of the BMP- or wingless-type MMTV integration site family(WNT)/β-catenin-signaling pathways. Moreover, the osteogenic effects of CG were inhibited by Noggin and DKK-1 which are classical inhibitors of the BMP and WNT/β-catenin-signaling pathways, respectively. Taken together, the results indicate that CG promotes the osteoblastic differentiation of ST2 cells through regulating the BMP/WNT signaling pathways. On this basis, CG may be a useful lead compound for improving the treatment of bone-decreasing diseases and enhancing bone regeneration.Jing Jian Lijuan Sun Xun Cheng Xiaofang Hu Jichao Liang Yong Chen 2015Acta Pharmaceutica Sinica B2015,5,5:16
8Melatonin: A master regulator of plant development and stress responses显示文摘Melatonin is a pleiotropic molecule with multiple functions in plants. Since the discovery of melatonin in plants, numerous studies have provided insight into the biosynthesis, catabolism, and physiological and biochemical functions of this important molecule. Here, we describe the biosynthesis of melatonin from tryptophan, as well as its various degradation pathways in plants. The identification of a putative melatonin receptor in plants has led to the hypothesis that melatonin is a hormone involved in regulating plant growth,aerial organ development, root morphology, and the floral transition. The universal antioxidant activity of melatonin and its role in preserving chlorophyll might explain its anti-senescence capacity in aging leaves. An impressive amount of research has focused on the role of melatonin in modulating postharvest fruit ripening by regulating the expression of ethylene-related genes.Recent evidence also indicated that melatonin functions in the plant's response to biotic stress,cooperating with other phytohormones and wellknown molecules such as reactive oxygen species and nitric oxide. Finally, great progress has been made towards understanding how melatonin alleviates the effects of various abiotic stresses, including salt, drought, extreme temperature, and heavy metal stress. Given its diverse roles, we propose that melatonin is a master regulator in plants.Chengliang Sun Lijuan Liu Luxuan Wang Baohai Li Chongwei Jinand Xianyong Lin 2021Journal of Integrative Plant Biology2021,63,1:14
9Mapping Heterotic Loci for Yield and Agronomic Traits Using Chromosome Segment Introgression Lines in Cotton显示文摘在现在的学习,一套染色体片断基因渗入排队(CSIL ) 使用 Gossypium hirsutum L。TM-1 作为接受者父母和 G。施主父母被用来为种间的混血儿探索杂种优势的基因基础的 barbadense Hai7124。个别地从与两个父母一起交叉的 CSIL 导出的 F1 人口的二个集合被设置调查 heterotic loci (HL ) 和替换效果 loci (SL ) 。58 HL 和 39 SL 的一个总数在 3 年里被识别。一稳定的 HL, hLP-A4-3,能在所有 3 年里被检测。三 HL, hBS-A8-1, hLP-D6-1,和 hSI-D7-11,能在 2 年里被检测。四 SL, sBS-D7-1, sLP-A8-1, sLP-D7-1,和 sLP-D12-1,能在 2 年里被检测。HL 和 SL 趋于在有靠近的位置的一些 HL 富有的染色体片断分布式。与在以前的研究检测的 QTL 相比, HL 与 QTL 显示出很少重叠,显示特点显型和杂种优势可能被 loci 的不同集合控制。基因效果的所有三种形式(部分 -- ,完整 -- ,在主导上) 被识别,当在主导上的效果做了主要贡献到杂种优势时。这些结果可以帮助为在棉花澄清杂种优势的遗传机制打了基础。Xian Guo Yuping Guo Jun Ma Fang Wang Mizhen Sun Lijuan Gui Jiajia Zhou Xianliang Song Xuezhen Sun Tianzhen Zhang 2013Journal of Integrative Plant Biology2013,55,8:13
10Overexpression of miR-30a in lung adenocarcinoma A549 cell line inhibits migration and invasion via targeting EYA2显示文摘MicroRNAs (miRNAs ) 是与癌症的致病有关的小非编码的 RNA 并且仔细的一个班。增加的证据显示 miR-30a 在癌症的发展期间起一个深刻作用。然而,在 non-small-cell 肺癌症(NSCLC ) 的 miR-30a 的功能仍然是模糊的。这里,我们发现 miR-30a 被 qRT-PCR 从 14 个病人在肺腺癌 A549 房间并且在织物样品减少,并且也发现在 A549 房间的 miR-30a 的 overexpression 由愈合创伤的试金禁止了移植和侵略然而并非房间增长和房间周期前进, matrigel 侵略试金,基于山的房间增长试金,和流动 基于cytometry 的房间周期分析分别地。我们进一步在肺腺癌房间行探索了 miR-30a-mediated 基因规定的潜在的机制。EYA2 是 miR-30a 的一个预言的目标,并且 EYA2 表示被 miR-30a 在乳癌房间禁止,这被发现了。我们证明 EYA2 是由在 A549 房间使用双酶的记者试金的 miR-30a 的一个直接目标并且证明 EYA2 蛋白质层次相反地在 A549 和 BEAS-2B 房间与 miR-30a 表示被相关。另外,我们也与表示向量和 miR-30a 模仿的 EYA2 由 cotransfection 在 A549 房间证实了 EYA2 overexpression 的营救效果。一起拿,我们的结果证明在肺腺癌 A549 房间的 miR-30a 的 overexpression 能禁止房间移植和侵略,它部分被归因于 EYA2 的减少表示。我们的调查结果建议 miR-30a 以后可以为肺腺癌的治疗被用作一个新潜在的目标。Yuncang Yuan Shangyong Zheng Qian Li Xudong Xiang Tangxin Gao Pengzhan Ran Lijuan Sun Qionglin Huang Fei Xie Jing Du Chunjie Xiao 2016Acta Biochimica et Biophysica Sinica2016,48,3:12
11Functionalization of small black phosphorus nanoparticles for targeted imaging and photothermal therapy of cancer显示文摘Black phosphorus(BP) nanomaterials have attracted extensive attention due to their unique physical,chemical, and biological properties. In this study, small BP nanoparticles were synthesized and modified with dextran and poly(ethyleneimine) for functionalization with folic acid and cyanine 7. The functionalized BP nanoparticles exhibit excellent biocompatibility, stability, and near infrared optical properties for targeted imaging of tumors through photoacoustic imaging and near-infrared fluorescence imaging.They also display high photothermal conversion efficiency for photothermal therapy of cancer. This work demonstrates the potential of functionalized small BP nanoparticles as an emerging nanotheranostic agent for the diagnosis and treatment of cancer.Lijuan Deng Yifan Xu Caixia Sun Baofeng Yun Qiao Sun Chongjun Zhao Zhen Li 2018Science Bulletin2018,63,14:12
12Paleoproterozoic basement beneath the southern Jiangxi Province:Evidence from U-Pb ages and Lu-Hf isotopes in zircons from the Doushui lamprophyre显示文摘这篇论文论述侵入的煌斑岩的 geochemical 分析在 Shangyou 县的古苏格兰的 Doushui 花岗石身体,南部的江西省。U-Pb 标明日期和 Hf 同位素分析特别从它为锆石被执行。Petrological 和 geochemical 特征证明煌斑岩属于 high-K,弱碱的辉石黑云母煌斑岩。它被 Mg #(0.74 ) , Ni (253 μg/g ) 和 Cr (893 μg/g ) 满足的高度描绘,并且也在不兼容的元素充实,例如 REE, Rb, Sr, Ba 和 K。它的原语融化,这被建议可能由 non-crust-derived 源于充实的披风 metasomatized 代理人。在煌斑岩标明日期锆石的结果的形态学和 LAM-ICPMS 显示他们是从深外壳的岩石捕获的 xenocrysts。在 ∼1.86 Ga 形成的大多数 xenocrystic 锆石,和在不同 Phanerozoic 时期的一些。Paleoproterozoic 锆石具有 magmatic 起源并且有类似的 176Hf/177 Hf 和 176Lu/177 Hf 比率,显示他们可能从一样的火的地下室岩石。年龄和从这地下室岩石的锆石的 Hf 同位素作文类似于在南部的浙江省的 Paleoproterozoic Danzhu 花岗石的那些,但是极其与 Nanling 地下室区分开来,建议学习区域可能是一向西在东方卡赛西亚·布洛克的 Paleoproterozoic Wuyishan 岩层的延期部分。这些 Paleoproterozoic 锆石有低 Hf 同位素作文,外壳的来源特征。这些锆石的 Hf 模型年龄和在他们以内的更旧的继承核心的存在,结合了可得到的其它数据由以前的研究报导了,建议 Paleoproterozoic 岩浆的来源是 Neoarchaean 外壳,在 Wuyishan 岩层暗示更旧的地下室的存在。U-Pb 年龄和五 Phanerozoic 锆石的 Hf 同位素显示那个 Paleoproterozoic 地下室经历了多重做的发生在古苏格兰, Indosinian 和早 Yanshanian 分别地。古苏格兰的 magmatism 也涉及少年外壳重做。YU JinHai WANG LiJuan O'REILLY S Y SHU LiangShu SUN Tao 2009Chinese Science Bulletin2009,54,9:10
13Structure and kinematic analysis of the deepwater area of the Qiongdongnan Basin through a seismic interpretation and analogue modeling experiments显示文摘Located at the northwest continental slope of the South China Sea, the Qiongdongnan Basin bears valley-shaped bathymetry deepening toward east. It is separated from the Yinggehai Basin through NW-trending Indo-ChinaRed River shear zone, and connected with NW subsea basin through the Xisha Trough. Along with the rapid progress of the deepwater exploration, large amounts of high resolution geophysical and geological data were accumulated. Scientific researches about deepwater basins kept revealing brand new tectonic and sedimentary discoveries. In order to summarize the structural features and main controlling factors of the deepwater Qiongdongnan Basin, a series of researches on basin architecture, fault activities, tectonic deformation and evolution were carried out. In reference to analogue modeling experiments, a tectonic situation and a basin formation mechanism were discussed. The researches indicate that: the northern boundary of the Qiongdongnan Basin is strongly controlled by No. 2 fault. The overlapping control of two stress fields from the east and the west made the central depression zone extremely thinned. Combined with the changed stress field, the segmentation of a preexisting weakness zone made the sags in the east experiencing different rifting histories from the west ones. The NE-trending west segment of the Qiongdongnan Basin experienced strong rifting during Eocene, while the roughly EW-trending sags in the east segment show strong rifting during late Eocene and early Oligocene.Local structures such as NW-trending basal fault and inherited uplifts controlled the lateral segmentation. So first order factors such as regional stress field and preexisting weakness zone controlled the basin zonation, while the second order factors determined the segmentation from east to west.SUN Zhen WANG Zhenfeng SUN Zhipeng WANG Zhangwen ZHANG Wei HE Lijuan 2015Acta Oceanologica Sinica2015,34,4:10
14Nitric oxide alleviates aluminum-induced oxidative damage through regulating the ascorbateglutathione cycle in roots of wheat显示文摘The possible association with nitric oxide(NO) and ascorbate-glutathione(As A-GSH) cycle in regulating aluminum(Al) tolerance of wheat(Triticum aestivum L.) was investigated using two genotypes with different Al resistance. Exposure to Al inhibited root elongation, and triggered lipid peroxidation and oxidation of As A to dehydroascorbate and GSH to glutathione disulfide in wheat roots. Exogenous NO significantly increased endogenous NO levels, and subsequently alleviated Al-induced inhibition of root elongation and oxidation of As A and GSH to maintain the redox molecules in the reduced form in both wheat genotypes. Under Al stress, significantly increased activities and gene transcriptional levels of ascorbate peroxidase, glutathione reductase, and dehydroascorbate reductase,were observed in the root tips of the Al-tolerant genotype Jian-864. Nitric oxide application enhanced the activity and gene transcriptional level of these enzymes in both wheat genotypes. g-Glutamylcysteine synthetase was not significantly Researaffected by Al or NO, but NO treatments increased the activity of glutathione peroxidase and glutathione S-transferase to a greater extent than the Al-treated wheat seedlings. Proline was significantly decreased by Al, while it was not affected by NO.These results clearly suggest that NO protects wheat root against Al-induced oxidative stress, possibly through its regulation of the As A-GSH cycle.Chengliang Sun Lijuan Liu Yan Yu Wenjing Liu Lingli Lu Chongwei Jin Xianyong Lin 2015Journal of Integrative Plant Biology2015,57,6:10
15Sedimentary Response of Different Fan Types to the Paleogene-Neogene Basin Transformation in the Kuqa Depression,Tarim Basin,Xinjiang Province显示文摘A group of alluvial fans formed in the early Paleogene represent marginal sedimentary facies at the foot of the South Tianshan Mountain,Kuqa Depression,Tarim Basin,Xinjiang province. Two types of fans occurred in the middle-late Paleogene Kumugeliemu and Suweiyi formations:one alluvial,and the other fan delta deposited in a lacustrine setting.Within the early Neogene Jidike Formation,coastal subaqueous fans developed,probably in a deeper water lacustrine setting.The three types of fans are stacked vertically in outcrop with the sequence in ascending order:bottom alluvial,middle fan-delta,and top subaqueous.The subaqueous is a typical coarse-fan deposit occurring in the glutinite member of the Jidike Formation in some wells.Laterally,from the foreland to the lacustrine settings,the distribution pattern of sedimentary facies represents the same three fan types sequentially.The spatial distribution of these fans was controlled by the Paleogene-Neogene Basin transformation,and evolution with different types of fans developed in the Kuqa Depression in response.In the Paleogene,the Kuqa Depression was a rift basin where an alluvial fan was deposited in the foreland setting,which,by early Neogene,became a foreland basin when the lake level changed. With any rise in lake level,fan-deltas migrated from lacustrine to foreland settings,whereas when the lake level fell,fan migration was reversed.In the early Neogene,with increasing slope and rising lake level,fans progressed and covered the previous fan-delta and lacustrine mudstone.Eventually, subaqueous fans developed,forming the present spatial configuration of these three fan types.GAO Zhiyong GUO Hongli ZHU Rukai ZHANG Lijuan SUN Yushan 2009Acta Geologica Sinica(English Edition)2009,83,2:10
16Dyes adsorption using a synthetic carboxymethyl cellulose-acrylic acid adsorbent显示文摘Removal of noxious dyes is gaining public and technological attention. Herein grafting polymerization was employed to produce a novel adsorbent using acrylic acid and carboxymethyl cellulose for dye removal. Scanning electron microscopy and Fourier-transform infrared spectroscopy verified the adsorbent formed under optimized reaction conditions. The removal ratio of adsorbent to Methyl Orange, Disperse Blue 2BLN and malachite green chloride reached to 84.2%, 79.6% and 99.9%, respectively. The greater agreement between the calculated and experimental results suggested that pseudo second-order kinetic model better represents the kinetic adsorption data. Equilibrium adsorptions of dyes were better explained by the Temkin isotherm. The results implied that this new cellulose-based absorbent had the universality for removal of dyes through the chemical adsorption mechanism.Genlin Zhang Lijuan Yi Hui Deng Ping Sun 2014Journal of Environmental Sciences2014,26,5:9
17Prevalence and molecular characteristics of Listeria monocytogenes in cooked products and its comparison with isolates from listeriosis cases显示文摘这研究试图在 Zigong 城市里在煮的产品调查流行和 Listeria monocytogenes 的分子的特征,中国。L 的全面出现。在商店和羊肉餐馆调查了的 ready-to-eat (RTE ) 的 monocytogenes 是 16.2%(141/873 ) 。13.5% 的出现在 RTE 猪肉被观察, 6.5% 在 RTE 蔬菜,并且非常, 24.0% 在也煮了羊肉或煮了将羊杂切碎加麦片纳入羊胃中煮成的食物。Serotype 1/2b (45.4%) , 1/2a (33.3%) ,和 1/2c (14.2%) 是占优势的类型。由基于 L 的打字的 multilocus 顺序(MLST ) 比较同种细胞的建筑群(CC ) 。从从中国, CC87, CC9, CC8,和 CC3 的不同区域的 Zigong 城市和 33 个 listeriosis 案例里的煮的食物的 monocytogenes 被显示在煮的产品和 CC87 流行, CC3 是在 33 诊所来源紧张的开始的二种经常的类型。所有 CC87 污点怀有最新报导的 Listeria 致病力岛 4 (LIPI-4 ) 基因碎片 ptsA,和所有 CC3 紧张拥有了 Listeria 致病力岛 3 (LIPI-3 ) 基因碎片 llsX。这些可以增加在中国在 listeriosis 情况中属于 CC87 和 CC3 的紧张的出现并且也从 Zigong 由于煮的产品的消费加重感染的风险。ST619 (serotype 1/2b ) 怀有 llsX 和 ptsA,显示在 Zigong 的一种潜在的 hypervirulent 顺序类型。Hong Wang Lijuan Luo Zhengdong Zhang Jianping Deng Yan Wang Yimao Miao Ling Zhang Xi Chen Xiang Liu Songsong Sun Bo Xiao Qun Li Changyun Ye 2018Frontiers of Medicine2018,12,1:9
18Dynamic channel reservation scheme based on priorities in LEO satellite systems显示文摘According to low earth orbit(LEO) satellite systems with users of different levels, a dynamic channel reservation scheme based on priorities is proposed. Dynamic calculation of the thresholds for reserved channels is the key of this strategy. In order to obtain the optimal thresholds, the traffic is predicted based on the high-speed deterministic movement property of LEO satellites firstly. Then, a channel allocation model based on Markov is established. Finally, the solution of the model is obtained based on the genetic algorithm. Without user location, this strategy effectively reduces handover failures and improves channel utilization by adjusting dynamically the thresholds according to traffic conditions. The simulation results show that the system's overall quality of service can be improved by this strategy.Jian Zhou Xiaoguo Ye Yong Pan Fu Xiao Lijuan Sun 2015Journal of Systems Engineering and Electronics2015,26,1:8
19Review of Chinese atmospheric science research over the past 70 years: Synoptic meteorology显示文摘Synoptic meteorology is a branch of meteorology that uses synoptic weather observations and charts for the diagnosis,study,and forecasting of weather.Weather refers to the specific state of the atmosphere near the Earth’s surface during a short period of time.The spatial distribution of meteorological elements in the atmosphere can be represented by a variety of transient weather phenomena,which are caused by weather systems of different spatial and temporal scales.Weather is closely related to people’s life,and its development and evolution have always been the focus of atmospheric scientific research and operation.The development of synoptic meteorology is closely related to the development of observation systems,dynamical theories and numerical models.In China,observation networks have been built since the early 1950 s.Up to now,a comprehensive meteorological observation systembased on ground,air and space has been established.In particular,the development of a new generation of dense radar networks,the development of the Fengyun satellite series and the implementation of a series of large field experiments have brought our understanding of weather from large-scale environment to thermal dynamics,cloud microphysical structure and evolution characteristics of meso and micro-scale weather systems.The development of observation has also promoted the development of theory,numerical model and simulation.In the early days,China mainly used foreign numerical models.Lately,China has developed numerical model systems with independent intellectual property rights.Based on the results of high-resolution numerical simulations,in-depth understanding of the initiation and evolution mechanism and predictability of weather at different scales has been obtained.Synoptic meteorology has gradually changed from an initially independent development to a multidisciplinary approach,and the interaction between weather and the change of climate and environment has become a hot and frontier topic in atmospheric science.This paper reviews the important scientific and technological achievements made in China over the past 70 years in the fields of synoptic meteorology based on the literatures in China and abroad,from six aspects respectively including atmospheric dynamics,synoptic-scale weather,typhoon and tropical weather,severe convective weather,numerical weather prediction and data assimilation,weather and climate,atmospheric physics and atmospheric environment.Zhiyong MENG Fuqing ZHANG Dehai LUO Zhemin TAN Juan FANG Jianhua SUN Xueshun SHEN Yunji ZHANG Shuguang WANG Wei HAN Kun ZHAO Lei ZHU Yongyun HU Huiwen XUE Yaping MA Lijuan ZHANG Ji NIE Ruilin ZHOU Sa LI Hongjun LIU Yuning ZHU 2019Science China Earth Sciences2019,62,12:7
20Analysis of Tianchi volcano activity in Changbai Mountain,NE China显示文摘Changbaishan volcano is the largest potential eruptive volcano in China.In this paper,seismic activity,horizontal displacement,vertical displacement and the fluid geochemistry data acquiring from Changbaishan Tianchi Volcano Observatory(TVO) in recent years are analyzed.The authors discussed the ability for the Changbaishan volcanic seismic monitoring and active level of Changbaishan volcano in recent years based on the fundamental monitoring results.The results show that Changbaishan volcano has experienced an unrest episode from 2002 to 2005,but its active level recovers to the background now.LIU Guoming YANG Jingkui WANG Lijuan SUN Jicai 2011Global Geology2011,14,1:7
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