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| 1 | Oncostatin M-induced cardiomyocyte dedifferentiation regulates the progression of diabetic cardiomyopathy through B-Raf/Mek/Erk signaling pathway显示文摘oncostatin M (OSM ) 能在 vivo 并且在 vitro 开始 cardiomyocyte dedifferentiation,这被报导了。导致 OSM 的 cardiomyocyte dedifferentiation 可能是为糖尿病的心肌症(DCM ) 的处理的一个新目标。这研究被设计在 cardiomyocyte dedifferentiation 和 DCM 的前进决定 OSM 的角色。一个老鼠 DCM 模型被建立在 vivo 评估 OSM 的效果。Echocardiography 被使用决定心脏的功能。染色的天狼星红被用来检测纤维变性区域。传播电子显微镜学被用来评估线粒体缺陷。实时聚合酶链反应和西方的污点分析被执行检测相对 mRNA 表情和 cardiomyocyte dedifferentiation 相关的蛋白质表情分别地。OSM 处理导致了类似的损害心脏的功能和心脏的超微结构缺陷到在 DCM 鼠标检测的那些。cardiomyocyte 的 dedifferentiation 标记的表达式(Runx1,和 -SM-actin) 与在控制组的那些相比在对待 OSM 的鼠标是起来调整的。为了推进,表明 OSM 的重要角色, OSM 受体大美人(O ko ) 老鼠被使用。在 O ko 老鼠, c 工具包的 cardiomyocytes dedifferentiation 标记, Runx1,和 atrial natriuretic 肽是下面调整的,与稀释 DCM 损害和废除 OSM/B-Raf/Mek/Erk 发信号小径。在结论,导致 OSM 的 cardiomyocyte dedifferentiation 在 DCM 的前进起一个关键作用。导致 OSM 的 cardiomyocyte dedifferentiation 的机制与通过 OSM 受体 O 表明小径的 B-Raf/Mek/Erk 被联系。 | Xiaotian Zhang Sai Ma Ran Zhang Shuang Li Di Zhu Dong Han Xiuiuan Li Congye Li Wei Yan Dongdong Sun Bin Xu Yabin Wang Feng Cao | 2016 | Acta Biochimica et Biophysica Sinica2016，48，3： | 7 |
| 2 | Deep learning classification of coastal wetland hyperspectral image combined spectra and texture features: A case study of Huanghe(Yellow) River Estuary wetland显示文摘This paper develops a deep learning classification method with fully-connected 8-layers characteristics to classification of coastal wetland based on CHRIS hyperspectral image. The method combined spectral feature and multi-spatial texture feature information has been applied in the Huanghe(Yellow) River Estuary coastal wetland.The results show that:(1) Based on testing samples, the DCNN model combined spectral feature and texture feature after K-L transformation appear high classification accuracy, which is up to 99%.(2) The accuracy by using spectral feature with all the texture feature is lower than that using spectral only and combing spectral and texture feature after K-L transformation. The DCNN classification accuracy using spectral feature and texture feature after K-L transformation was up to 99.38%, and the outperformed that of all the texture feature by 4.15%.(3) The classification accuracy of the DCNN method achieves better performance than other methods based on the whole validation image, with an overall accuracy of 84.64% and the Kappa coefficient of 0.80.(4) The developed DCNN model classification algorithm ensured the accuracy of all types is more balanced, and it also greatly improved the accuracy of tidal flat and farmland, while kept the classification accuracy of main types almost invariant compared to the shallow algorithms. The classification accuracy of tidal flat and farmland is up to 79.26% and 56.72%respectively based on the DCNN model. And it improves by about 2.51% and 10.6% compared with that of the other shallow classification methods. | Yabin Hu Jie Zhang Yi Ma Xiaomin Li Qinpei Sun Jubai An | 2019 | Acta Oceanologica Sinica2019，38，5： | 5 |
| 3 | Enhanced production of seed oil with improved fatty acid composition by overexpressing NAD^(+)-dependent glycerol-3-phosphate dehydrogenase in soybean显示文摘There is growing interest in expanding the production of soybean oils(mainly triacylglycerol, or TAG) to meet rising feed demand and address global energy concerns. We report that a plastidlocalized glycerol-3-phosphate dehydrogenase(GPDH), encoded by GmGPDHp1 gene, catalyzes the formation of glycerol-3-phosphate(G3 P), an obligate substrate required for TAG biosynthesis.Overexpression of GmGPDHp1 increases soybean seed oil content with high levels of unsaturated fatty acids(FAs), especially oleic acid(C18:1), without detectably affecting growth or seed protein content or seed weight. Based on the lipidomic analyses, we found that the increase in G3 P content led to an elevated diacylglycerol(DAG) pool, in which the Kennedy pathwayderived DAG was mostly increased, followed by PC-derived DAG, thereby promoting the synthesis of TAG containing relatively high proportion of C18:1. The increased G3 P levels induced several transcriptional alterations of genes involved in the glycerolipid pathways. In particular, genes encoding the enzymes responsible for de novo glycerolipid synthesis were largely upregulated in the transgenic lines, in-line with the identified biochemical phenotype. These results reveal a key role for GmGPDHp1-mediated G3 P metabolism in enhancing TAG synthesis and demonstrate a strategy to modify the FA compositions of soybean oils for improved nutrition and biofuel. | Ying Zhao Pan Cao Yifan Cui Dongxu Liu Jiapeng Li Yabin Zhao Siqi Yang Bo Zhang Runnan Zhou Minghao Sun Xuetian Guo Mingliang Yang Dawei Xin Zhanguo Zhang Xin Li Chen Lv Chunyan Liu Zhaoming Qi Jingyu Xu Xiaoxia Wu Qingshan Chen | 2021 | Journal of Integrative Plant Biology2021，63，6： | 4 |
| 4 | Effects of hepatocyte growth factor overexpressed bone marrow‐derived mesenchymal stem cells on prevention from left ventricular remodelling and functional improvement in infarcted rat hearts显示文摘 | Shenxu Wang Xing Qin Dongdong Sun Yunfang Wang Xiaoyan Xie Weiwei Fan Yabin Wang Dong Liang Xuetao Pei Feng Cao | 2012 | Cell Biochem Funct2012，，7： | 2 |
| 5 | 显示文摘 | Sun Yabin Ding Xiaobin Zheng Zhaohui | 2007 | Eu- ropean Polymer Journal2007，43，： | 1 |
| 6 | 显示文摘 | Sun Yabin Ding Xiaobin Zheng Zhaohui | 2007 | Macromol Rapid Commun2007，28，： | 1 |
| 7 | 显示文摘 | Sun Yabin Ding Xiaobin Zheng Zhaohui | 2006 | Chem Commun2006，26，： | 1 |
| 8 | Surface initiated ATRP in the synthesis of iron oxide/polystyrene core/shell nanoparticles显示文摘 | Yabin Sun Xiaobin Ding Zhaohui Zheng Xu Cheng Xinhua Hu Yuxing Peng | 2006 | European Polymer Journal2006，，3： | 1 |
| 9 | Fiber-Optic Microstructure Sensors:A Review显示文摘This paper reviews a wide variety of fiber-optic microstructure(FOM)sensors,such as fiber Bragg grating(FBG)sensors,long-period fiber grating(LPFG)sensors,Fabry-Perot interferometer(FPI)sensors,Mach-Zchnder interferometer(MZI)sensors,Michelson interferometer(MI)sensors,and Sagnac interferometer(SI)sensors.Each FOM sensor has been introduced in the terms of structure types,fabrication methods,and their sensing applications.In addition,the sensing characteristics of different structures under the same type of FOM sensor are compared,and the sensing characteristics of the all FOM sensors,including advantages,disadvantages,and main sensing parameters,are summarized.We also discuss the future development of FOM sensors. | Zengling RAN Xiu HE Yunjiang RAO Dong SUN Xiaojuan QIN Debiao ZENG Wangwei CHU Xiankun LI Yabin WEI | 2021 | Photonic Sensors2021，11，2： | 1 |
| 10 | Physical mechanism of performance adjustment in selective buried oxide n-MOSFETs显示文摘Dear editor,FDSOI MOSFETs do not rely on channel doping to control short channel effects;they overcome the barriers of conventional bulk MOSFETs by means of scaling. Owing to the presence of the buried oxide insulator (BOX), FDSOI MOSFETs offer many additional benefits over bulk MOSFETs. | Qin HUANG Renhua LIU Yabin SUN Xiaojin LI Yanling SHI Changfeng WANG DuANDuan LIAO Ming TIAN | 2019 | Science China(Information Sciences)2019，62，6： | 0 |
| 11 | Nuclear Physics and Interdiscipline——Modification of Structure and Optical Band-gap of nc-Si : H Films with Ion Irradiation显示文摘 | Zhu Yabin Wang Zhiguang Sun Jianrong Yao Cunfeng Shen Tielong Chang Hailong Li Bingsheng Wei Kongfang Pang Lilong Sheng Yanbin Cui Minghuan Zhang Hongpeng Li Yuanfei Wang Ji Zhu Huiping | 2011 | IMP & HIRFL Annual Report2011，，1： | 0 |
| 12 | Micro-raman Study on a-Si, nc-Si and c-Si irradiated by 6 MeV Bi-ions显示文摘 | Zhu Yabin Wang Zhiguang Sun Jianrong Yao Cunfeng Shen Tielong Chang Hailong Li Bingsheng Wei Kongfang Pang Lilong Sheng Yanbin Cui Minghuan Zhang Hongpeng Li Yuanfei Wang Ji Zhu Huiping | 2011 | IMP & HIRFL Annual Report2011，，1： | 0 |
| 13 | Damage Processes and Magnetic Moments Distribution in Fe3O4 Magnetic Insulator Films Irradiated by Swift Heavy Ions: theoretical modelisation and experimental results显示文摘 | Sun Jianrong Wang Zhiguang Jin Yunfan Zhu Yabin Wei Kongfang | 2011 | IMP & HIRFL Annual Report2011，，1： | 0 |
| 14 | Structural and Magnetic Properties Studies on Swift Heavy Ion (SHI) Irradiated Fe-based Amorphous Alloys显示文摘 | Sun Jianrong Wang Zhiguang Jin Yunfang Zhu Yabin Shen Tielong Yao Cunfeng Pang Lilong Wei Kongfang Sheng Yanbin Chang Hailong Zhang Hongpeng Wang Ji Zhu Huiping | 2011 | IMP & HIRFL Annual Report2011，，1： | 0 |
| 15 | Modification of LiTaO3 Crystal by Low-energy He-ion Implantation显示文摘 | Pang Lilong Wang Zhiguang Jin Yunfan Sun Jianrong Yao Cunfeng Cui Minghuan Wei Kongfang Shen Tielong Sheng Yanbin Zhu Yabin Li Yuanfei Wang Ji Zhu Huiping | 2011 | IMP & HIRFL Annual Report2011，，1： | 0 |
| 16 | Investigation of Structural Modification of Lithium Tantalate Crystal Implanted by Low Energy H-ion显示文摘 | Pang Lilong Wang Zhiguang Yao Cunfeng Li Yuanfei Sun Jianrong Li Bingsheng Shen Tielong Cui Minghuan Wei Kongfang Sheng Yanbin Zhu Yabin Wang Ji Zhu Huiping | 2011 | IMP & HIRFL Annual Report2011，，1： | 0 |
| 17 | Hardening of Tungsten Induced by 200 keV Helium Ions显示文摘 | Cui Minghuan Wang Zhiguang Yao Cunfeng Shen Tielong Li Bingsheng Sun Jianrong Pang Lilong Sheng Yanbin Zhu Yabin Li Yuanfei | 2011 | IMP & HIRFL Annual Report2011，，1： | 0 |
| 18 | 3 - 3 Modifications of Iron-based Amorphous Alloys under Swift Heavy Ions (SHI) Irradiation Investigated by 57Fe Mossbauer Spectrometry显示文摘 | Sun Jianrong Wang Zhiguang Yao Cunfeng Shen Tielong Pang Lilong Zhu Yabin Sheng Yanbin Ma Yizhun Gou Jie Wei Kongfang Li Fashen | 2010 | IMP & HIRFL Annual Report2010，，1： | 0 |
| 19 | 3 - 19 Preparation and Ultra-long PVP Assembly of Aligned Nanofibers显示文摘 | Zhou Ming Sun Jianrong Yao Cunfeng Gou Jie Sheng Yanbin Shen Tielong Zhu Yabin Pang Lilong Cui Minghuan Wang Zhiguang Xie Erqing | 2010 | IMP & HIRFL Annual Report2010，，1： | 0 |
| 20 | 3-4 Compatibility Tests of SIMP and T91 Steels in Static LBE显示文摘Because of their good mechanical properties under irradiation up to 500 ?C, ferritic/martensitic steels are consideredto be the promising structural materials for advanced nuclear reactors. However, severe corrosion of structuralmaterials occurs in the presence of LBE in advanced nuclear reactors, especially at high temperature[1]. Therefore,the selection of the structural material exposed to LBE is an extremely complex problem and compatibility testsare required. | Zhang Hongpeng Yao Cunfeng Wang Zhiguang Wang Ji Zhu Huiping Sheng Yanbin Sun Jianrong Chang Hailong Wang Dong Li Bingsheng Shen Tielong Zhu Yabin Pang Lilong Cui Minghuan Wei Kongfang | 2014 | IMP & HIRFL Annual Report2014，，1： | 0 |
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