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| 1 | Lumbar pedicle cortical bone trajectory screw显示文摘 | Song Tengfei Wellington K Hsu Ye Tianwen | 2014 | Chinese Medical Journal2014，，21： | 11 |
| 2 | Xuefuzhuyu decoction for hyperlipidemia: a systematic review and Meta-analysis of randomized clinical trails显示文摘OBJECTIVE:To evaluate the efficacy and safety of Xuefuzhuyu decoction for hyperlipidemia.METHODS:Randomized clinical trials on hyperlipidemia treated by Xuefuzhuyu decoction,either alone or with Western Medicine,were searched in electronic databases.Databases searched were:MEDLINE,Allied and Complementary Medicine Database,EMBASE,The Cochrane Library 2013(Issue4),China National Knowledge Infrastructure Database,Chinese Biomedical Literature Database,and Wanfang Database up to 2 May,2013.Study selection,data extraction,quality assessment,and data analysis were conducted according to the Cochranestandards.RESULTS:Six randomized clinical trials involving748 patients(373 patients in the treatment group,375 patients in the control group)were included in the analysis.The studies were of low methodological quality.Meta-analysis indicated that the effect of Xuefuzhuyu decoction on hyperlipidemia was better than that in the control group[n=748,OR=5.07,95%CI(3.40,7.58),P<0.01].Weighted mean differencesin total cholesterol,low-densitylipoprotein cholesterol,triglycerides,and high-density lipoprotein cholesterol were﹣0.79,﹣0.74,﹣0.44,0.16,respectively,and Meta-analysis revealed that the treatment group was better than the control group with 95%CI(﹣1.21,﹣0.36),(﹣0.94,﹣0.55),(﹣0.77,﹣0.11),(0.04,0.27),respectively(all P<0.05).Some adverse events in evaluated studies wererecorded.CONCLUSION:Xuefuzhuyu decoction may be effective for treating hyperlipidemia.The studies we analyzed were of low methodological quality,which indicates that the above findings should be considered cautiously.Therefore,more strictly designed large-scale randomized clinical trials are needed to evaluate the efficacy of Xuefuzhuyu decoction in hyperlipidemia. | Jiangquan Liao Jiaxing Tian Tengfei Li Weijiang Song Weihan Zhao Jinhang Du | 2014 | Journal of Traditional Chinese Medicine2014，34，4： | 5 |
| 3 | NEDD9 promotes cancer stemness by recruiting myeloid-derived suppressor cells via CXCL8 in esophageal squamous cell carcinoma显示文摘Objective:Esophageal squamous cell carcinoma(ESCC)has high morbidity and mortality rates worldwide.Cancer stem cells(CSCs)may cause tumor initiation,metastasis,and recurrence and are also responsible for chemotherapy and radiotherapy failures.Myeloid-derived suppressor cells(MDSCs),in contrast,are known to be involved in mediating immunosuppression.Here,we aimed to investigate the mechanisms of interaction of CSCs and MDSCs in the tumor microenvironment.Methods:ESCC tissues and cell lines were evaluated.Neural precursor cell expressed,developmentally downregulated 9(NEDD9)was knocked down and overexpressed by lentiviral transfection.Quantitative PCR,Western blot,immunohistochemistry,cell invasion,flow cytometry,cell sorting,multiplex chemokine profiling,and tumor growth analyses were performed.Results:Microarray analysis revealed 10 upregulated genes in esophageal CSCs.Only NEDD9 was upregulated in CSCs using the sphere-forming method.NEDD9 expression was correlated with tumor invasion(P=0.0218),differentiation(P=0.0153),and poor prognosis(P=0.0373).Additionally,NEDD9 was required to maintain the stem-like phenotype.Screening of chemokine expression in ESCC cells with NEDD9 overexpression and knockdown showed that NEDD9 regulated C-X-C motif chemokine ligand 8(CXCL8)expression via the ERK pathway.CXCL8 mediated the recruitment of MDSCs induced by NEDD9 in vitro and in vivo.MDSCs promoted the stemness of ESCC cells through NEDD9 via the Notch pathway.Conclusions:As a marker of ESCC,NEDD9 maintained the stemness of ESCC cells and regulated CXCL8 through the ERK pathway to recruit MDSCs into the tumor,suggesting NEDD9 as a therapeutic target and novel prognostic marker for ESCC. | Dongli Yue Shasha Liu Tengfei Zhang Yong Wang Guohui Qin Xinfeng Chen Huanyu Zhang Dong Wang Lan Huang Feng Wang Liping Wang Song Zhao Yi Zhang | 2021 | Cancer Biology & Medicine2021，18，3： | 4 |
| 4 | Unique NiFe–NiCoO2 hollow polyhedron as bifunctional electrocatalysts for water splitting显示文摘It is of significance to design of stable and cost-effective electrocatalyst for water splitting with high efficiency in an alkaline medium.The major obstacles for practical application of water splitting devices are lack of high-efficiency and low-cost electrocatalysts with low overpotential for both HER and OER.In this paper,we report a NiFe alloy decorated NiCoO2 hollow polyhedron(denoted as Ni Fe–Ni Co O2)by using[NiFe(CN)6]- intercalated NiCo–LDH as precursor.As evidenced by the electrochemical active surface area,the resultant Ni Fe–Ni Co O2 composite shows unique hollow nanostructure,which can not only provide abundant mass transport channels,but also increase the contact area of the NiFe–Ni Co O2 material with the electrolyte.The overpotential(η)demand is 286 mV for OER and 102 mV for HER at the current density of 10 mA/cm2 in an alkaline medium of 1 M KOH for the NiFe/NiCoO2 composite.This work provides a new pathway for preparation of the highly efficient bifunctional electrocatalysts for water splitting. | Rong Shi Jiaxin Wang Zhi Wang Tengfei Li Yu-Fei Song | 2019 | Journal of Energy Chemistry2019，28，6： | 2 |
| 5 | Effect of strawberry vein banding virus and strawberry mottle virus co-infection on the growth and development of strawberry显示文摘Strawberry mottle virus(SMoV)and strawberry vein banding virus(SVBV)cause diseases on strawberry plants,but the effect of coinfection of SMoV and SVBV on the growth,development,and defense system of strawberry(Fragaria×ananassa Duchesne)remains unknown.We investigated the effect of SMoV and SVBV coinfection on strawberry cultivar‘Benihope’.The results showed that stem diameter,leaf size,leaf number,relative chlorophyll content,total chlorophyll content,photosynthetic parameters,and stomatal aperture of SMoV and SVBV co-infected strawberry(VIS)plants were in a weaker level than uninfected control plants,indicating that viruses inhibited the growth and photosynthesis of strawberry plants.Furthermore,the initiation of flowering and fruiting stages of VIS plants were delayed by about three weeks compared with the controls,and the fruiting period was shortened,demonstrating that the reproduction of VIS plants was inhibited.Fruit quality was damaged in VIS plants due to a significant increase in fruit firmness and titratable acidity and decrease in total soluble solid content than control fruits.More dead cells and H_(2)O_(2) accumulated along the veins of VIS leaves,and the content of abscisic acid and catalase activity significantly increased,whereas anthocyanin content was lower than that of control plants.The results demonstrate that SVBV and SMoV coinfection inhibits the growth and development of‘Benihope’strawberry plants,and the plants respond to viruses by regulating stomatal aperture,the accumulation of ABA and antioxidants.To our knowledge,this study contributes information to understand how both viruses impair the strawberry growth and development for the first time. | LINGJIAO FAN DAN SONG YINGWEI KHOO MENGMENG WU TENGFEI XU XIAOLI ZHAO HONGQING WANG | 2022 | BIOCELL2022，46，1： | 1 |
| 6 | StRAP2.3, an ERF-Ⅶ transcription factor, directly activates StInvInh2 to enhance cold-induced sweetening resistance in potato显示文摘Potato invertase inhibitor(StInvInh2)positively regulates cold-induced sweetening(CIS)resistance by inhibiting the activity of vacuolar invertase.The distinct expression patterns of StInvInh2 have been thoroughly characterized in different potato genotypes,but the related CIS ability has not been characterized.The understanding of the regulatory mechanisms that control StInvInh2 transcription is unclear.In this study,we identified an ERF‐Ⅶ transcription factor,StRAP2.3,that directly regulates StInvInh2 to positively modulate CIS resistance.Acting as a nuclear-localized transcriptional activator,StRAP2.3 directly binds the ACCGAC cis-element in the promoter region of StInvInh2,enabling promoter activity.Overexpression of StRAP2.3 in CIS-sensitive potato tubers induced StInvInh2 mRNA abundance and increased CIS resistance.In contrast,silencing StRAP2.3 in CIS-resistant potato tubers repressed the expression of StInvInh2 and decreased CIS resistance.We conclude that cold-responsive StInvInh2 is due to the binding of StRAP2.3 to the ACCGAC cis-element in the promoter region of StInvInh2.Overall,these findings indicate that StRAP2.3 directly regulates StInvInh2 to positively modulate CIS resistance,which may provide a strategy to improve the processing quality of potatoes. | Weiling Shi Yuhao Song Tiantian Liu Qiuqin Ma Wang Yin Yuchen Shen Tengfei Liu Chunyan Jiang Kai Zhang Dianqiu Lv Botao Song Jichun Wang Xun Liu | 2021 | Horticulture Research2021，8，1： | 1 |
| 7 | The Application of Mathematical Programming Approaches to Estimating Container Port Production Efficiency显示文摘 | Kevin Cullinane Dong-Wook Song Tengfei Wang | 2005 | Journal of Productivity Analysis2005，，1： | 1 |
| 8 | A Cast Copper Rotor Induction Motor for Small Commercial EV Traction: Electromagnetic Design, Analysis, and Experimental Tests显示文摘According to the demands of the small commercial electric vehicle(EV)traction driving system,an 18kW inverter-driven induction motor(IM)with a die-casting copper squirrel cage rotor for traction drive was designed and evaluated.The 2D finite element model of the designed IM was built by considering the nonlinearity of core materials,and the geometric parameters of the motor were optimized.The operational performance of torque versus speed characteristics and the efficiency over the speed range under the rated(continuous)and overload condition were investigated.Finally,the designed inverter-driven IM was developed and the performance of the IM operating in three typical modes were tested respectively.The experimental results of the designed motor operating in various driven mode were compared with that of 2D FEM.All the results proved that the designed inverter-driven IM could meet the target specification of the small commercial EV. | Qian Zhang Huijuan Liu Zhenyang Zhang Tengfei Song | 2018 | CES Transactions on Electrical Machines and Systems2018，2，4： | 1 |
| 9 | The Application of Mathematical Programming Approaches to Estimating Container Port Production Efficiency显示文摘 | Kevin Cullinane Dong-Wook Song Tengfei Wang | 2005 | Journal of Productivity Analysis2005，24，09： | 1 |
| 10 | Genome degradation promotes Salmonella pathoadaptation by remodeling fimbriae-mediated proinflammatory response显示文摘Understanding changes in pathogen behavior(e.g.increased virulence,a shift in transmission channel)is critical for the public health management of emerging infectious diseases.Genome degradation via gene depletion or inactivation is recognized as a pathoadaptive feature of the pathogen evolving with the host.However,little is known about the exact role of genome degradation in affecting pathogenic behavior,and the underlying molecular detail has yet to be examined.Using large-scale global avian-restricted Salmonella genomes spanning more than a century,we projected the genetic diversity of Salmonella Pullorum(bvSP)by showing increasingly antimicrobial-resistant ST92 prevalent in Chinese flocks.The phylogenomic analysis identified three lineages in bvSP,with an enhancement of virulence in the two recently emerged lineages(L2/L3),as evidenced in chicken and embryo infection assays.Notably,the ancestor L1 lineage resembles the Salmonella serovars with higher metabolic flexibilities and more robust environmental tolerance,indicating stepwise evolutionary trajectories towards avian-restricted lineages.Pan-genome analysis pinpointed fimbrial degradation from a virulent lineage.The later engineeredfim-deletion mutant,and all other five fimbrial systems,revealed behavior switching that restricted horizontal fecal-oral transmission but boosted virulence in chicks.By depleting fimbrial appendages,bvSP established persistent replication with less proinflammation in chick macrophages and adopted vertical transovarial transmission,accompanied by ever-increasing intensification in the poultry industry.Together,we uncovered a previously unseen paradigm for remodeling bacterial surface appendages that supplements virulence-enhanced evolution with increased vertical transmission. | Xiao Zhou Xiamei Kang Jiaqi Chen Yan Song Chenghao Jia Lin Teng Yanting Tang Zhijie Jiang Xianqi Peng Xiaoxi Tao Yiwei Xu Linlin Huang Xuebin Xu Yaohui Xu Tengfei Zhang Shenye Yu Jiansen Gong Shaohui Wang Yuqing Liu Guoqiang Zhu Corinna Kehrenberg Franois-Xavier Weill Paul Barrow Yan Li Guoping Zhao Min Yue | 2023 | National Science Review2023，10，10： | 0 |
| 11 | New Discovery of Upper Crustal High-and Low-Velocity Belts and High-Velocity Core in the Tarim Basin显示文摘The Tarim Basin is the biggest oil-and gas-bearing basin in China,which has undergone long-term and complicated evolutionary history.During each evolutional stage and in different sub-basins in the same stage,the Tarim Basin has different proto-types,and it is thus named a composite and superimposed basin.A study on the basement nature of such a complex but significant to the national oil and gas strategy basin is of great significance(Huang Chenjun et al.,2017).Based on earthquake data,detailed velocity structure of deep basin can be obtained in order to research the basement nature. | WANG Tengfei JIN Zhenkui YU Xiaoxia CHENG Rihui SONG Xue YANG Baoju LI Shuo SHI Shuting | 2019 | Acta Geologica Sinica(English Edition)2019，93，1： | 0 |
| 12 | Progress in Enzymatic Production of Trehalose显示文摘Trehalose is a non-reducing disaccharide, and widespread in nature. It is a typical stress metabolite that can protect macromolecules such as proteins in organisms under extreme conditions. Therefore, trehalose has been widely used in food, medicine and cosmetics. Trehalose is extracted from yeast or synthesized by chemical method. Due to the high cost of traditional methods, trehalose is mainly produced by enzymatic methods. There are mainly three pathways: TPS/TPP, TreY/TreZ and TreS. These enzymatic systems are expressed mainly through heterologous expression. | Longxiang SONG Shaojie YANG Hongling LIU Tengfei WANG | 2021 | Agricultural Biotechnology2021，10，1： | 0 |
| 13 | Photo-induced fusion of monodisperse polymer microspheres:A novel strategy for constructing topological microsphere clusters with improved stability显示文摘The preparation of monodisperse azobenzene(Azo)polymer microspheres by dispersion polymerization was reported.The photo-induced fusion of Azo polymer microspheres was successfully achieved during the process of reversible trans-cistrans photoisomerization of Azo units,and induced various unique“microsphere molecular”clusters or“microsphere polymers”.Encouraged by this interesting phenomenon,microsphere clusters of different topological structures were stabilized by the in situ acetal cross-linking chemistry.The photo-induced fusion polymerization of monodisperse polymer microspheres provides a new strategy for designing photo-responsive clusters and allows for control over the mechanical properties of microspheres with high spatiotemporal resolution. | Zixiang He Su Shen Gong Zhang Tengfei Miao Xiaoxiao Cheng Zhao Wang Qingping Song Wei Zhang | 2023 | Aggregate2023，4，5： | 0 |
| 14 | Potato tonoplast sugar transporter 1 controls tuber sugar accumulation during postharvest cold storage显示文摘Cold-induced sweetening(CIS),the undesirable sugar accumulation in cold-stored potato(Solanum tuberosum L.)tubers,is a severe postharvest issue in the potato processing industry.Although the process of sucrose hydrolysis by vacuolar invertase during potato CIS is well understood,there is limited knowledge about the transportation of sucrose from the cytosol to the vacuole during postharvest cold storage.Here,we report that among the three potato tonoplast sugar transporters(TSTs),StTST1 exhibits the highest expression in tubers during postharvest cold storage.Subcellular localization analysis demonstrates that StTST1 is a tonoplast-localized protein.StTST1 knockdown decreases reducing sugar accumulation in tubers during low-temperature storage.Compared to wild-type,potato chips produced from StTST1-silenced tubers displayed significantly lower acrylamide levels and lighter color after cold storage.Transcriptome analysis manifests that suppression of StTST1 promotes starch synthesis and inhibits starch degradation in cold-stored tubers.We further establish that the increased sucrose content in the StTST1-silenced tubers might cause a decrease in the ABA content,thereby inhibiting the ABA-signaling pathway.We demonstrate that the down-regulation ofβ-amylase StBAM1 in StTST1-silenced tubers might be directly controlled by ABA-responsive element-binding proteins(AREBs).Altogether,we have shown that StTST1 plays a critical role in sugar accumulation and starchmetabolism regulation during postharvest cold storage.Thus,our findings provide a newstrategy to improve the frying quality of cold-stored tubers and reduce the acrylamide content in potato chips. | Tengfei Liu Md Abu Kawochar Shahnewaz Begum Enshuang Wang Tingting Zhou Shenglin Jing Tiantian Liu Liu Yu Bihua Nie Botao Song | 2023 | Horticulture Research2023，10，4： | 0 |
| 15 | Performance Evaluation of a 60kW IPM Motor for Medium Commercial EV Traction Application显示文摘This paper presented the design and performance analysis of a 60kW interior permanent-magnet(IPM)synchronous motor used as traction drive in a medium commercial electric vehicle(EV),according to the traction requirements of the electric vehicle under the rated operating conditions and overload conditions.The key dimensions were calculated on the basis of the permanent-magnet(PM)motor theory,and the 2D finite element method(FEM)simulation model of the IPM motor was built by using 2D Maxwell software.The influence geometric structures of the IPM motor including the PM dimensions and skewed PMs on electromagnetic torque were investigated,and the temperature distribution of the motor under rated operating condition and the condition of maximum speed were calculated.Finally,the simulation results of the IPM motor running in various operating modes were compared with the experimental results,which demonstrated that the designed IPM motor can match all requirements of the medium commercial electric vehicle driving applications. | Zhenyang Zhang Huijuan Liu Tengfei Song Qian Zhang Wenluan Hu Wei Liu | 2019 | CES Transactions on Electrical Machines and Systems2019，3，2： | 0 |
| 16 | Effects of the ambient fine particulate matter(PM2.5) exposure on urinary metabolic profiles in rats using UPLC-Q-TOF-MS显示文摘In order to study the damage of ambient fine particulate matter(PM2.5) to organism in the environment,the method of urinary metabolomics was used to detect the potential endogenous metabolites and their related metabolic pathways to clarify the toxicity mechanisms. Particles of PM2.5 collected from the fibrous membrane were extracted ultrasonically and dissolved in physiological saline to prepare PM2.5 suspension. The solution of saline and fine particular matter was injected into the trachea of rats respectively. The rats were injected two times a week for four weeks. Samples of 24-h urine were collected at the 14 th day after the end of exposure, and the ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry(UPLC-Q-TOF-MS) was used for the metabolomics detection. Principal component analysis(PCA) was used to investigate the global metabolomic alterations and a clear separation in the scatter diagram were observed. 17 potential endogenous metablites were identified from urinary samples in rats by UPLC-Q-TOF-MS. The primary metabolism pathways involved pentose and glucuronate interconversions, starch and sucrose metabolism, tryptophan metabolism, tyrosine metabolism, phenylalanine metabolism, purine metabolism, acetaminophen metabolism pathway, retinol metabolism and valproic acid metabolism pathway.The results are helpful to understand the toxicological mechanisms of PM2.5 and screened out potential biomarkers of rats which exposure to PM2.5. | Lin Zhang Tengfei Xu Zifeng Pi Meizhu Zheng Fengrui Song Zhiqiang Liu | 2019 | Chinese Chemical Letters2019，30，1： | 0 |
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