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| 1 | XA23 Is an Executor R Protein and Confers Broad-Spectrum Disease Resistance in Rice显示文摘 | Chunlian Wang Xiaoping Zhang Yinglun Fan Ying Gao Qinlong Zhu Chongke Zheng Tengfei Qin Yanqiang Li Jinying Che Mingwei Zhang Bing Yang Yaoguang Liu Kaijun Zhao | 2015 | Molecular Plant2015，8，2： | 55 |
| 2 | Sinomenine ester derivative inhibits glioblastoma by inducing mitochondria-dependent apoptosis and autophagy by PI3K/AKT/mTOR and AMPK/mTOR pathway显示文摘Glioblastoma multiforme(GBM)in the central nervous system is the most lethal advanced glioma and currently there is no effective treatment for it.Studies of sinomenine,an alkaloid from the Chinese medicinal plant,Sinomenium acutum,showed that it had inhibitory effects on several kinds of cancer.Here,we synthesized a sinomenine derivative,sino-wcj-33(SW33),tested it for antitumor activity on GBM and explored the underlying mechanism.SW33 significantly inhibited proliferation and colony formation of GBM and reduced migration and invasion of U87 and U251 cells.It also arrested the cell cycle at G2/M phase and induced mitochondria-dependent apoptosis.Differential gene enrichment analysis and pathway validation showed that SW33 exerted anti-GBM effects by regulating PI3 K/AKT and AMPK signaling pathways and significantly suppressed tumorigenicity with no obvious adverse effects on the body.SW33 also induced autophagy through the PI3 K/AKT/mTOR and AMPK/mTOR pathways.Thus,SW33 appears to be a promising drug for treating GBM effectively and safely. | Xiangjin Zheng Wan Li Huanli Xu Jinyi Liu Liwen Ren Yihui Yang Sha Li Jinhua Wang Tengfei Ji Guanhua Du | 2021 | Acta Pharmaceutica Sinica B2021，11，11： | 15 |
| 3 | Raindrop Size Distribution Parameters Retrieved from Guangzhou S-band Polarimetric Radar Observations显示文摘According to the statistical shape–slope(μ–Λ) relationship observed for the first time by several 2 D-Video-Distrometers(2 DVD) in southern China, a constrained gamma(C-G) model was proposed for the retrieval of rain drop size distributions(DSDs) from Guangzhou S-band polarimetric radar observations. Two typical precipitation processes were selected to verify the accuracy of the retrieval scheme. The μ–Λ relationship: Λ = 0.0241μ2 + 0.867μ + 2.453 was obtained based on the 2 DVD observation results from at Huizhou Longmen station, which is a very representative location in the area. Relying on the Guangzhou polarimetric radar measurements of radar reflectivity(ZHH) and differential reflectivity(ZDR), the gamma(Γ) size distribution parameters(N0, μ, and Λ) can be retrieved by the C-G model retrieval scheme. The results show that the Guangzhou polarimetric radar retrievals of DSDs were close to the2 DVD observations at Guangzhou Maofengshan station. The rain rate, mass mean diameter, and normalized intercept parameter of radar retrievals were in good agreement with the 2 DVD observations, and the relative errors were less than 10%. The overall accuracy of the retrieval scheme was high. The retrieval scheme has established the relationship between the polarimetric radar measurements and gamma size distribution parameters. It will be helpful to in-depth research and application of the dual-polarization radar data in microphysical precipitation processes analysis,as well as convection-resolved numerical model data assimilation and prediction effect evaluation. | Xiantong LIU Qilin WAN Hong WANG Hui XIAO Yu ZHANG Tengfei ZHENG Lu FENG | 2018 | Journal of Meteorological Research2018，32，4： | 11 |
| 4 | A plastic damage model for concrete structure cracks with two damage variables显示文摘Based on the concepts of continuum damage theory,a new plastic damage model for concrete crack failure is developed through studying the basic damage mechanics.Two damage variables,tensile damage variable for tensile damage and shear damage variable for compressive damage,are adopted to represent the influence of microscopic damage on material macromechanics properties under tensile and compressive loadings.The yield criteria and flow rule determining the plasticity of concrete are established in the effective stress space,which is convenient to decouple the damage process from the plastic process and calibrate material parameters with experimental results.Meanwhile,the plastic part of the proposed model can be implemented by back-Euler implicit algorithm,and the damage part is explicit.Consequently,there exist robust algorithms for integrating the constitutive relations using finite element method.Comparison with several experimental results shows that the model is capable of simulating the nonlinear performance of concrete under multiaxial stress state and can be applied to practical concrete structures. | ZHENG FuGang WU ZhongRu GU ChongShi BAO TengFei HU Jiang | 2012 | Science China(Technological Sciences)2012，55，11： | 6 |
| 5 | Determination of the available energy,standardized ileal digestibility of amino acids of fermented corn germ meal replacing soybean meal in growing pig diets显示文摘Three experiments were conducted to compare the digestible(DE),metabolizable energy(ME),and standardized ileal digestibility(SID)of amino acids(AA)in fermented corn germ meal(FCGM)and soybean meal(SBM),and evaluate the effects of FCGM replacing SBM in growing pig diets.In Exp.1,18 barrows with initial body weight(BW)of 60.2±3.40 kg were randomly allotted to 3 treatments with 6 replicates per treatment.The control diet used corn as the only energy ingredient,and 2 test diets were made by replacing 25.8%of corn with FCGM or SBM.The DE and ME of FCGM were less(P<0.01)than those of SBM.In Exp.2,18 barrows(59.3±2.52 kg BW)with ileal T-cannulas were randomly allotted to 3 treatments with 6 replicates per treatment.The SID of arginine,tryptophan and proline were greater(P<0.05)and the tyrosine was less(P=0.01)in SBM compared with FCGM.In Exp.3,144 growing pigs(56.1±5.22 kg BW)were randomly allotted to 4 treatments with 6 pens per treatment(3 barrows and 3 gilts per pen).Four diets(FCGM0,FCGM10,FCGM20 and FCGM30)were formulated using FCGM to replace 0%,10%,20%and 30%of SBM,respectively.The ME and SID values of AA of SBM and FCGM were determined by Exp.1 and 2.Results showed that increasing FCGM inclusion quadratically(P<0.05)increased the average daily gain(ADG),average daily feed intake,and the levels of serum immunoglobulin G(IgG)and urea nitrogen,and linearly(P<0.05)increased the serum IgM,the propanoic acid,butyric acid,total volatile fatty acid(VFA)and the Shannon index of microbiota in feces.Besides,the relative abundance of genus Streptococcus in FCGM0,Lactobacillus in FCGM10 and Lachnospiraceae in FCGM30 were increased(P<0.05)compared with other treatments.In conclusion,we recommend replacing 11.80%of SBM with FCGM to obtain the optimal ADG of growing pigs.Moreover,as the ratio of FCGM replacing SBM increased in diet,the immunity,intestinal microbiota and total VFA composition of growing pigs were improved. | Tengfei He Yuhui Zheng Xiangshu Piao Shenfei Long | 2022 | Animal Nutrition2022，，2： | 6 |
| 6 | An Imported Case and an Infected Close Contact of the Omicron Variant of SARS-CoV-2—Guangdong Province,China,December 13,2021显示文摘On November 27,2021,a 67-year-old male returning from Canada via airplane was transferred to the central isolation hotel in Shanghai.During the quarantine,his 1st,4th,7th,and 14th days of specimens returned negative for severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),which causes coronavirus disease 2019(COVID-19).On December 11,he completed 14 days of centralized isolation and returned to Guangzhou from Shanghai via airplane,then he was closed-loop transferred to Yuexiu District for a 7-day home isolation.On December 12,the local Community Health Service Center routinely collected his throat swab and the result returned to COVID-19 positive on December 13,2021.He was transported to the Guangzhou Eighth People’s Hospital for isolated treatment by negative pressure ambulance on the same day.The patient had two inflamed lungs according to the chest computed tomography(CT)examination,but his most recently updated condition was stable.An estimated 600 close contacts were identified and were placed in centralized isolation.On December 16,one of the close contacts,a 70-year-old female also tested positive for COVID-19.She lived on the lower floor of the same type of apartment as the imported case and spent 19 hours in the same building. | Kuibiao Li Zhonghua Zheng Xiang Zhao Qing Zeng Tengfei Zhou Qianfang Guo Yao Hu Wenbo Xu Zhoubin Zhang Baisheng Li | 2022 | China CDC weekly2022，4，5： | 4 |
| 7 | Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis显示文摘Depression is a serious public-health issue.Recent reports have suggested higher susceptibility to viral infections in depressive patients.However,how depression affects antiviral innate immune signaling remains unknown.Here,we revealed a reduction in expression of Abelson helper integration site 1(AHI1)in the peripheral blood mononuclear cells(PBMCs)and macrophages from the patients with major depressive disorder(MDD),which leads to attenuated antiviral immune response.We found that depression-related arginine vasopressin(AVP)induces reduction of AHI1 in macrophages.Further studies demonstrated that AHI1 is a critical stabilizer of basal type-I-interferon(IFN-I)signaling.Mechanistically,AHI1 recruits OTUD1 to deubiquitinate and stabilize Tyk2,while AHI1 reduction downregulates Tyk2 and IFN-I signaling activity in macrophages from both MDD patients and depression model mice.Interestingly,we identified a clinical analgesic meptazinol that effectively stimulates AHI1 expression,thus enhancing IFN-I antiviral defense in depression model mice.Our study promotes the understanding of the signaling mechanisms of depression-mediated antiviral immune dysfunction,and reveals meptazinol as an enhancer of antiviral innate immunity in depressive patients. | Hong-Guang Zhang Bin Wang Yong Yang Xuan Liu Junjie Wang Ning Xin Shifeng Li Ying Miao Qiuyu Wu Tingting Guo Yukang Yuan Yibo Zuo Xiangjie Chen Tengfei Ren Chunsheng Dong Jun Wang Hang Ruan Miao Sun Xingshun Xu Hui Zheng | 2022 | Cell Research2022，32，10： | 3 |
| 8 | Hybrid rice yield response to potted-seedling machine transplanting and slow-release nitrogen fertilizer application combined with urea topdressing显示文摘Machine transplanting and the application of slow-release nitrogen(N) fertilizer(SRNF) have played vital roles in the modernization of rice production. We aimed to determine the effects of potted-seedling transplanting—a new machine-transplanting method—and SRNF on hybrid rice yields. A 2-year splitplot experiment(2016–2017) was conducted in Meishan, Sichuan province, China, using two machinetransplanting methods(potted-seedling and blanket-seedling) and three N treatments. Total green leaf area, high-effective leaf area and its rate at heading, net photosynthetic rate of flag leaves 7 days after heading, glutamate synthase(GOGAT) and glutamine synthase(GS) activity after heading, dry matter production, and N accumulation at heading and maturity increased under the potted-seedling method or 70% SRNF as a base + 30% urea application at the panicle initiation stage(SBUP). Stem diameter and number of small and of all vascular bundles at the neck–panicle node in potted-seedling plants increased as a result of increasing numbers of effective panicles, secondary branches, and spikelets. In pottedseedling plants, treatment with SBUP increased the number of large and total vascular bundles at the panicle–neck internode and the number of differentiated and surviving secondary branches and spikelets and decreased the number of ineffective tillers and degenerated secondary branches and spikelets. We conclude that the potted-seedling machine transplanting method and SRNF combined with urea topdressing can strengthen the source–sink relationship in rice, resulting in higher yields. | Tengfei Lyu Jie Shen Jun Ma Peng Ma Zhiyuan Yang Zou Dai Chuangang Zheng Min Li | 2021 | The Crop Journal2021，9，4： | 3 |
| 9 | Precise carbon structure control by salt template for high performance sodium-ion storage显示文摘Carbon materials are considered to be one of the most promising anode materials for sodium-ion batteries(SIBs),but the well-ordered graphitic structure limits the intercalation of sodium ions.Besides,the sluggish intercalation kinetics of sodium ions impedes the rate performance.Thus,the precise structure control of carbon materials is important to improve the battery performance.Herein,a 3D porous hard-soft composite carbon(3DHSC)was prepared using the NaCl as the template and phenolic resin and pitch as carbon precursors.The NaCl template restrains the growth of the graphite crystallite during the carbonization process,resulting in small graphitic domains with expanded interlayer spacing which is favorable for the sodium storage.Moreover,the Na Cl templates help to create abundant mesopores and macropores for fast sodium ion diffusion.The porous structure and the graphite crystalline structure can be precisely controlled by simply adjusting the mass ratio of Na Cl,and thus,the suitable structure can be prepared to reach high capacity and rate performance while keeping a relatively high Coulombic efficiency.Typically,a high reversible capacity(215 mA h g^(-1)at 0.05 A g^(-1)),an excellent rate capability(97 mA h g^(-1)at 5 A g^(-1)),and a high initial Coulombic efficiency(60%)are achieved. | Dong Qiu Tengfei Cao Jun Zhang Si-Wei Zhang Dequn Zheng Haoliang Wu Wei Lv Feiyu Kang Quan-Hong Yang | 2019 | Journal of Energy Chemistry2019，28，4： | 3 |
| 10 | High-resolution genetic mapping of rice bacterial blight resistance gene Xa23显示文摘 | Chunlian Wang Yinglun Fan Chongke Zheng Tengfei Qin Xiaoping Zhang Kaijun Zhao | 2014 | Molecular Genetics and Genomics2014，，5： | 3 |
| 11 | Recombinant expression of different mutant K-ras gene in pancreatic cancer Bxpc-3 cells and its effects on chemotherapy sensitivity显示文摘K-ras is a member of ras gene family which is involved in cell survival,proliferation and differentiation.When a mutation occurs in ras gene,the activation of Ras proteins may be prolonged to induce oncogenesis.However,the relationship between K-ras mutation and clinical outcomes in pancreatic cancer patients treated with chemotherapy agents is still under debate.In this study,we constructed five pAcGFP1-C3 plasmids for different types of K-ras gene(WT,G12V,G12R,G12D,and G13D)and stably transfected human pancreatic cancer Bxpc-3 cells with these genes.The wild type and mutant clones showed a comparable growth and expression of K-Ras-GFP fusion protein.The expression of some K-ras mutations resulted in a reduced sensitivity to gefitinib,5-FU,docetaxel and gemcitabine,while showed no effects on erlotinib or cisplatin.Moreover,compared with the wild type clone,K-Ras downstream signals(phospho-Akt and/or phospho-Erk)were increased in K-ras mutant clones.Interestingly,different types of K-ras mutation had non-identical K-Ras downstream signal activities and drug responses.Our results are the first to reveal the relationship between different K-ras mutation and drug sensitivities of these anti-cancer drugs in pancreatic cancer cells in vitro. | SHAO TengFei ZHENG YuanTing ZHAO Bei LI Tao CHENG KeGuang CAI WeiMin | 2014 | Science China(Life Sciences)2014，57，10： | 2 |
| 12 | Integrated parameter inversion analysis method of a CFRD based on multi-output support vector machines and the clonal selection algorithm显示文摘 | Dongjian Zheng Lin Cheng Tengfei Bao Beibei Lv | 2013 | Computers and Geotechnics2013，，： | 1 |
| 13 | Enhanced ferro-/piezoelectric properties of tape-casting-derived Er^(3+)-doped Ba_(0.85)Ca_(0.15)Ti_(0.9)Zr_(0.1O3) optoelectronic thick films显示文摘Er^(3+)-doped Ba_(0.85)Ca_(0.15)Ti_(0.9)Zr_(0.1O3)(xEr-BCTZ,x=0,0.005,0.01,0.015)multifunctional thick films were prepared by the tape-casting method,using sol-gel-derived nano-sized powders as the matrix material.The surface morphologies,photoluminescence,and electrical properties were investigated.Dense microstructures with pure perovskite structure were obtained in the thick films.By doping an appropriate amount of Er^(3+),the samples exhibit superior up-conversion photoluminescence performance and simultaneously enhanced electrical performances.In addition,relatively higher texture fractions(with the largest value of 83.5%)were realized through introducing plate-like BaTiO_(3) templates to make the thick film grow by the[001]_(c) orientation.And the ferro-/piezoelectric properties of the thick films were further improved,showing potential in the applications of micro-optoelectronic devices. | Jie XU Qiling LU Jinfeng LIN Cong LIN Xinghua ZHENG Tengfei LIN Xiao WU | 2020 | Journal of Advanced Ceramics2020，9，6： | 1 |
| 14 | Dual-ionic imidazolium salts to promote synthesis of cyclic carbonates at atmospheric pressure显示文摘Novel dual-ionic imidazolium salts are shown to display excellent catalytic activity for cycloaddition of carbon dioxide and epoxides under room temperature and atmospheric pressure(0.1 MPa)without any solvent and co-catalyst leading to 96.1%product yield.It can be reused five times to keep the product yield over 90%.These intriguing results are attributed to a new reaction mechanism,which is supported by theoretical calculations along with the measurements of ^(13)C NMR spectrum and Fourier transform infrared spectroscopy(FT-IR).The excellent catalytic activity can be traced to a CO_(2)-philic group along with an electrophilic hydrogen atom.Our work shows that incorporation of CO_(2)-philic group is an feasible pathway to develop the new efficient ionic liquids. | Tengfei Wang Danning Zheng Beibei An Yi Liu Tiegang Ren HansÅgren Li Wang Jinglai Zhang Mårten S.G.Ahlquist | 2022 | Green Energy & Environment2022，7，6： | 1 |
| 15 | MOF-derived multi-interface carbon-based composites with enhanced polarization loss and efficient microwave absorption显示文摘Metal-organic framework materials(MOFs)have been widely stu-died because of their adjustable composition and controllable structure in the field of microwave absorption(MA).Therein,Prussian blue analogs(PBA)have attracted the attention of researchers with ultra-high metal content.However,the attenua-tion ability of microwave for PBA-based composites is still unsatis-factory up to now.Therefore,the NiFe/CoFe@C composites were prepared by carbonizing polymetallic PBA(NiCoFe PBA)materials in this work,and the influence of different metal alloy components on MA was explored by adjusting the ratio of metal ions(Ni^(2+)/Co^(2+)).Moreover,the NiFe/CoFe@C composites have rich interfaces and enhance the polarization loss due to the introduction of Ni and it has an optimal performance at 2.7 mm that is the reflection loss(RL)is−41.49 dB and an effective absorption bandwidth(EAB)is 7.12 GHz with 1/1(Ni^(2+)/Co^(2+)).The above data provides a research idea for obtaining light and efficient absorbers. | Hongjiao Qu Peng Zheng Tao Wang Xingyu Yu Junjie Pan Xiaoli Fan Tengfei Zhang Xin Sun Jianping He | 2022 | International Journal of Smart and Nano Materials2022，13，3： | 1 |
| 16 | Integrated Parameter Inversion Analysis Method of a CFRD Based on Multi-output Support Vector Machines and the Clonal Selec- tion Algorithm显示文摘 | Zheng Dongjian Cheng Lin Bao Tengfei | 2013 | Computers and Geotechnics2013，47，： | 1 |
| 17 | Integrated parameter inversion analysis method of a CFRD based on multi-output support vector machines and the clonal selection algorithm显示文摘 | ZHENG DONGJIAN CHENG LIN BAO TENGFEI | 2013 | Computers and Geotechnics2013，47，1： | 1 |
| 18 | ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells显示文摘Programmed DNA recombination in mammalian cells occurs predominantly in a directional manner.While random DNA breaks are typically repaired both by deletion and by inversion at approximately equal proportions,V(D)J and class switch recombination(CSR)of immunoglobulin heavy chain gene overwhelmingly delete intervening sequences to yield productive rearrangement.What factors channel chromatin breaks to deletional CSR in lymphocytes is unknown.Integrating CRISPR knockout and chemical perturbation screening we here identify the Snf2-family helicase-like ERCC6L2 as one such factor.We show that ERCC6L2 promotes double-strand break end-joining and facilitates optimal CSR in mice.At the cellular levels,ERCC6L2 rapidly engages in DNA repair through its C-terminal domains.Mechanistically,ERCC6L2 interacts with other end-joining factors and plays a functionally redundant role with the XLF end-joining factor in V(D)J recombination.Strikingly,ERCC6L2 controls orientation-specific joining of broken ends during CSR,which relies on its helicase activity.Thus,ERCC6L2 facilitates programmed recombination through directional repair of distant breaks. | Xiaojing Liu Tingting Liu Yafang Shang Pengfei Dai Wubing Zhang Brian J.Lee Min Huang Dingpeng Yang Qiu Wu Liu Daisy Liu Xiaoqi Zheng Bo O.Zhou Junchao Dong Leng-Siew Yeap Jiazhi Hu Tengfei Xiao Shan Zha Rafael Casellas X.Shirley Liu Fei-Long Meng | 2020 | Cell Research2020，30，9： | 1 |
| 19 | Blue-shifted and naked-eye recognition of H_(2)PO_(4)- and acetylacetone based on a luminescent metal-organic framework with new topology and good stability显示文摘Fluorescence detecting both organic and inorganic analytes has aroused tremendous scientific interests, because fluorescence techniques have high sensitivity and are easy to operate. A new threedimensional(3D) MOF {[(CH_(3))_(2)NH_(2)][Zn_(3)(bbip)(BTDI)1.5(OH)]·DMF·MeOH·3H_(2)O}n(JXUST-13, bbip = 2,6-bis(benzimidazol-1-yl)pyridine and H_(4)BTDI = 5,5-(benzo[c][1,2,5]thiadiazole-4,7-diyl)diisophthalic acid)with new 4,4,8-connceted topology has been successfully synthesized and structurally characterized. Importantly, JXUST-13 could recognize H_(2)PO_(4)-and acetylacetone(Acac) by obvious fluorescence blue shift and slight enhancement with the detection limits of 2.70 μmol/L and 0.21 mmol/L, respectively. In addition, JXUST-13 exhibits relatively good thermal stability, chemical stabilities as well as reusability, and the analytes could be distinguished by naked eye and fluorescence test paper. Remarkably, JXUST-13 is the first dual-responsive MOF sensor based on fluorescence blue shift for the detection of H_(2)PO_(4)-and Acac with good selectivity in a handy, economic, and environmentally friendly manner. | Shuli Yao Hui Xu Tengfei Zheng Yunwu Li Haiping Huang Jun Wang Jinglin Chen Suijun Liu Herui Wen | 2023 | Chinese Chemical Letters2023，34，4： | 0 |
| 20 | Effect of silicon-doped calcium phosphate cement on angiogenesis based on controlled macrophage polarization显示文摘Vascularization is an important early indicator of osteogenesis involving biomaterials. Bone repair and new bone formation are associated with extensive neovascularization. Silicon-based biomaterials have attracted widespread attention due to their rapid vascularization. Although calcium phosphate cement (CPC) is a mature substitute for bone, the application of CPC is limited by its slow degradation and insufficient promotion of neovascularization. Calcium silicate (CS) has been shown to stimulate vascular endothelial proliferation. Thus, CS may be added to CPC (CPC–CS) to improve the biocompatibility and neovascularization of CPC. In the early phase of bone repair (the inflammatory phase), macrophages accumulate around the biomaterial and exert both anti- and pro-inflammatory effects. However, the effect of CPC–CS on macrophage polarization is not known, and it is not clear whether the effect on neovascularization is mediated through macrophage polarization. In the present study, we explored whether silicon-mediated macrophage polarization contributes to vascularization by evaluating the CPC–CS-mediated changes in the immuno-environment under different silicate ion contents both in vivo and in vitro. We found that the silicon released from CPC–CS can promote macrophage polarization into the M2 phenotype and rapid endothelial neovascularization during bone repair. Dramatic neovascularization and osteogenesis were observed in mouse calvarial bone defects implanted with CPC–CS containing 60% CS. These findings suggest that CPC–CS is a novel biomaterial that can modulate immune response, promote endothelial proliferation, and facilitate neovascularization and osteogenesis. Thus, CPC–CS shows potential as a bone substitute material. | Soomin Lee Zheng Li Dehua Meng Qinming Fei Libo Jiang Tengfei Fu Ze Wang Shuhao Liu Jian Zhang | 2021 | Acta Biochimica et Biophysica Sinica2021，53，11： | 0 |
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