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| 1 | Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013显示文摘 | Marie Ng Tom Fleming Margaret Robinson Blake Thomson Nicholas Graetz Christopher Margono Erin C Mullany Stan Biryukov Cristiana Abbafati Semaw Ferede Abera Jerry P Abraham Niveen M E Abu-Rmeileh Tom Achoki Fadia S AlBuhairan Zewdie A Alemu Rafael Alfonso | 2014 | The Lancet2014,,: | 7 |
| 2 | 健康领域的文化能力显示文摘1背景
尽管人类对其他社会的兴趣纵贯历史的各个阶段,但是检验不同文化概念对人类健康实践的影响从20世纪才开始,当时是伴随着长期的人类学田野调查产生的,这些田野调查揭露了不同文化之间相关卫生实践的多样性、复杂性和连续性。 | Napier A D Ancarno C Butler B Calabrese j Chater A Chatterjee H Guesnet F Home R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams AC Willott C Wilson J Woolf K | 2016 | 中国卫生政策研究2016,9,2: | 5 |
| 3 | Increased catabolism and decreased unsaturation of ganglioside in patients with inflammatory bowel disease显示文摘AIM: To investigate whether accelerated catabolism of ganglioside and decreased ganglioside content contribute to the etiology of pro-inflammatory intestinal disease. METHODS: Intestinal mucosa from terminal ileum or colon was obtained from patients with ulcerative colitis or inflammatory Crohn's disease(n = 11) undergoing bowel resection and compared to control samples of normal intestine from patients with benign colon polyps(n = 6) and colorectal cancer(n = 12) in this observational case-control study. Gangliosides and phospholipids of intestinal mucosa were characterized by class and ceramide or fatty acid composition using liquid chromatography triple-quad mass spectrometry. Content and composition of ganglioside classes GM1, GM3, GD3, GD1 a, GT1 and GT3 were compared among subject groups. Content and composition of phospholipid classes phosphatidylcholine(PC) and phosphatidylethanolamine were compared among subject groups. Unsaturation index of individual ganglioside and phospholipid classes was computed and compared among subject groups. Ganglioside catabolism enzymes beta-hexosaminidase A(HEXA) and sialidase-3(NEU3) were measured in intestinal mucosa using western blot and compared among subject groups. RESULTS: Relative GM3 ganglioside content was 2-fold higher(P < 0.05) in intestine from patients with inflammatory bowel disease(IBD) compared to control intestine. The quantity of GM3 and ratio of GM3/GD3 was also higher in IBD intestine than control tissue(P < 0.05). Control intestine exhibited 3-fold higher(P < 0.01) relative GD1 a ganglioside content than IBD intestine. GD3 and GD1 a species of ganglioside containing three unsaturated bonds were present in control intestine, but were not detected in IBD intestine. The relative content of PC containing more than two unsaturated bonds was 30% lower in IBD intestine than control intestine(P < 0.05). The relative content of HEXA in IBD intestine was increased 1.7-fold(P < 0.05) and NEU3 was increased 8.3-fold(P < 0.01) compared to normal intestine. Intestinal mucosa in IBD is characterized by increased GM3 content, decreased GD1 a, and a reduction in polyunsaturated fatty acid constituents in GD3, GD1 a and PC.CONCLUSION: This study suggests a new paradigm by proposing that IBD occurs as a consequence of increased metabolism of specific gangliosides. | John J Miklavcic Glen K Shoemaker Vera C Mazurak M Tom Clandinin Tasha DL Hart Kareena L Schnabl Gordon M Lees Bodil MK Larsen Oliver F Bathe Alan BR Thomson M Tom Clandinin | 2015 | World Journal of Gastroenterology2015,21,35: | 3 |
| 4 | 文化、不平等性与卫生服务提供显示文摘1动态不平等性对基层医疗卫生人力的影响
政治、社会、文化、专业群体皆建立在一致且常规的人类行为之上。当遭受巨大变革和内外压力时,这些群体会变得十分脆弱。尤其在动荡时期,这些群体往往更关注社会和文化的差异性,而非二者的一致性。尽管社会中的个体思维和行为会呈现较大的差异,但对健康的感知具有统一性,并在更广范围人群内尤为突出,这主要归因于文化价值观的作用。广义的文化心态会随着时间和地理位置的不同而不同,就像健康的社会决定因素也会因文化类型的不同而产生差异。 | Napier A D Ancarno C Butler B Calabrese J Chater A Chatterjee H Guesnet F Horne R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams A C Willott C Wilson J Woolf K | 2016 | 中国卫生政策研究2016,9,3: | 2 |
| 5 | A custom microarray platform for analysis of microRNA gene expression显示文摘 | PARKER J PEROU C M | 2004 | Nat Methods2004,1,: | 1 |
| 6 | The promoter of a basic PR1-like gene,AtPRB1,from Arabidopsis establishes an organ-specific expression pattern and responsiveness to ethylene and methyl jasmonate显示文摘 | SANTAMARIA M Thomson C J Read N D | 2001 | Plant Molecular Biology2001,47,: | 1 |
| 7 | 医疗卫生保健文化的反思及促进健康与文化融合的建议显示文摘1医疗卫生保健文化的反思1.1健康文化与医学知识如果医务人员有充足的时间对患者进行诊断并帮助患者进行社区护理,就可在节省卫生费用的同时改善健康结果。整合型社区护理能缩小不同文化背景和群体健康需求的差异。然而,全球范围内对整合型社区护理的投入较少,原因之一就是20世纪对临床服务的重视弱化了卫生服务提供过程中的同情心理。当然,患者也对医学知识存在显性和隐性的影响(特别是当其因不遵医嘱而受到指责时)。 | Napier A D Ancarno C Butler B Calabrese J Chater A Chatterjee H Guesnet F Horne R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams A C Willott C Wilson JWoolf K | 2016 | 中国卫生政策研究2016,9,4: | 1 |
| 8 | Fabrication of biodegradable polymer scaffolds to engineer trabe-cular bone显示文摘 | Thomson R C Yaszemski M J Powers J M | 1995 | Journal of Biomaterials Science-polymer Edition1995,7,1: | 1 |
| 9 | Estrogenicity of pyrethroid insecticide metabolites显示文摘 | MCCARTHY A R THOMSON B M SHAW I C | 2006 | Journal of Environmental Monitoring2006,8,: | 1 |
| 10 | Rebound of a coal tar creosote plume following partial source zone treatment with permanganate 显示文摘 | THOMSON N R FRASER M J LAMARCHE C | 2008 | Journal of Contaminant Hydrology2008,102,1: | 1 |
| 11 | The ties that bind:the strength of consumers' emotional attachments to brands 显示文摘 | THOMSON M MACINNIS D J PARK C W | 2005 | Journal of Consumer Psychology2005,15,1: | 1 |
| 12 | HPV testing in combi- nation with liquid-based cytology in primary cervical screening (AR- TISTIC): a randomised controlled trial显示文摘 | Kitchener HC Almonte M Thomson C | 2009 | Lancet Oncol2009,10,7: | 1 |
| 13 | HPV testing in combination with liquid-based cytology in primary cervi- cal screening(ARTISTIC): a randomised controlled trial显示文摘 | Kitchener HC Almonte M Thomson C | 2009 | Lancet Oncol2009,10,7: | 1 |
| 14 | Carbide precipitation in martensite during the early stages of tempering Cr and Mo-containing low alloy steels显示文摘 | THOMSON R C MILLER M K | 1998 | Acla Materialia1998,46,6: | 1 |
| 15 | A custom microarray platform for analysis of microRNA gene expression显示文摘 | Thomson J M Parker J Perou C M | 2004 | Nat Methods2004,1,1: | 1 |
| 16 | Relapse of hyperprolactinemia aRer transsphenoidal surgery for micro-prolactinoma:lessons from long-term follow-up显示文摘 | GRAY C E TEASDALE G M | 2002 | Neuro-surgery2002,50,1: | 1 |
| 17 | Oral calcium inhibits rectal epithelial proliferation m familial adenomatous polyposis显示文摘 | FHOMAS M G THOMSON J P S WILLIAMSON R C N | 1993 | Br J Surg1993,30,: | 1 |
| 18 | Fractionated atrial electrograms during sinus rhythm: relation- ship to age, voltage, and conduction velocity显示文摘 | ROBERTS THOMSON K C KISTLER P M SANDER S P | 2009 | Heart Rhythm2009,6,5: | 1 |
| 19 | High solids nitroxide- mediated microemulsion polymerization of MMA with a small a- mount of styrene and synthesis of (MMA-co-St) -block-( BMA-co- St) polymers显示文摘 | Thomson M E Ness J S Sehmidt S C | 2011 | Macromolecules2011,44,6: | 1 |
| 20 | Withering syndrome of the black abalone Haliotis cracberodii (teach) : water temperature, food availability, and parasites as possible causes显示文摘 | FRIEDMAN C S THOMSON M CHUN C | 1997 | Shell Wsh Res1997,16,: | 1 |