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| 1 | Construction of a genetic map with SRAP markers and localization of the gene responsible for the first-flower-node trait in cucumber (Cucumis sativus L.)显示文摘With an F 2 population from the cross of two cucumber inbred lines, S06 and S52, sequence-related amplified polymorphism (SRAP) was used to construct a genetic linkage map in cucumber (Cucumis sativus L.). Sixty-four SRAP primer combinations generated 108 polymorphic bands in the F 2 population analysis. The average of polymorphic bands produced by one primer pair was 1.5, and the maximum was 5. Using Mapmaker 3.0, a linkage map was constructed, which consisted of 77 SRAP markers distributed in nine linkage groups (LOD≥3.0) and spanned 1114.2 cM with an average interval of 14.5 cM between markers. The gene for the first-flower-node trait, termed ffn, was mapped to linkage group Ⅸ, flanked by DC1EM5 and ME7EM2A at 10.3 cM and 12.1 cM distance, respectively. | PANJunsong WANGGang LIXiaozun HEHuanle WUAizhong CAIRun | 2005 | Progress in Natural Science:Materials International2005，15，5： | 26 |
| 2 | Management of cytokine release syndrome related to CAR-T cell therapy显示文摘Chimeric antigen receptor T (CAR-T) cell therapy is a novel cellular immunotherapy that is widely used to treat hematological malignancies, including acute leukemia, lymphoma, and multiple myeloma. Despite its remarkable clinical effects, this therapy has side effects that cannot be underestimated. Cytokine release syndrome (CRS) is one of the most clinically important and potentially life-threatening toxicities. This syndrome is a systemic immune storm that involves the mass cytokines releasing by activated immune cells. This phenomenon causes multisystem damages and sometimes even death. In this study, we reported the management of a patient with recurrent and refractory multiple myeloma and three patients with acute lymphocytic leukemia who suffered CRS during CAR-T treatment. The early application of tocilizumab, an anti-IL-6 receptor antibody, according to toxicity grading and clinical manifestation is recommended especially for patients who suffer continuous hyperpyrexia, hypotensive shock, acute respiratory failure, and whose CRS toxicities deteriorated rapidly. Moreover, low doses of dexamethasone (5-10 mg/day) were used for refractory CRS not responding to tocilizumab. The effective management of the toxicities associated with CRS will bring additional survival opportunities and improve the quality of life for patients with cancer. | Hongli Chen Fangxia Wang Pengyu Zhang Yilin Zhang Yinxia Chen Xiaohu Fan Xingmei Cao Jie Liu Yun Yang Baiyan Wang Bo Lei Liufang Gu Ju Bai Lili Wei Ruili Zhang Qiuchuan Zhuang Wanggang Zhang Wanhong Zhao Aili He | 2019 | Frontiers of Medicine2019，13，5： | 21 |
| 3 | Therapeutic effect of artemisinin on lupus nephritis mice and its mechanisms显示文摘在这研究,我们由比较豺狼座肾炎(行) 之间的差别在豺狼座肾炎老鼠和它的机制上调查了 artemisinin (艺术) 的治疗学的效果在分子的生物学, immunohistochemistry,和组织病理学说给艺术和控制老鼠的老鼠。结果证明艺术能显著地减轻症状,减少尿 protein/24 h 的水平,并且减轻病理学的肾的损害。在在 NF-Bp65 蛋白质的表示的四个组之中的差别,原子 factor-B ( NF-B )活动,并且在肾的织物转变生长 factor-1 ( TGF-1 ) mRNA 的表达式建议那个艺术罐头降低肿瘤坏死因素的浆液层次--(TNF-)并且 interleukin-6 ( IL-6 )并且在行鼠标的肾的纸巾禁止 NF-Bp65 蛋白质和 NF-B 和 TGF-1 mRNA 的表达式。这些结果证明使用艺术对待行老鼠可靠、有效,并且它的治疗学的机制应该仔细与艺术能显然减少的事实有关是 TNF-6 和 IL-6 和下面调整的浆液层次在肾的纸巾的 NF-Bp65 蛋白质和 NF-B 和 TGF-1 mRNA 的表示。 | Xili Wu Wanggang Zhang Xingmin Shi Peng An Wansen Sun Zhu Wang | 2010 | Acta Biochimica et Biophysica Sinica2010，42，12： | 17 |
| 4 | Localization of genes for lateral branch and female sex expression and construction of a molecular linkage map in cucumber (Cucumis sativus L.) with RAPD markers显示文摘A cucumber (Cucumis sativus L.) molecular linkage map, including 79 random-amplified polymorphic DNAs (RAPD) and two genes , lb for lateral branch and f for female sex expression, is constructed from a cross between a line, S52, with weak lateral growing ability and staminate from Dabieshan Mountains area in China and another line, S06, with strong lateral growing ability and gynoecious from Europe. The map contains nine linkage groups and spans 1110.0 cM with an average distance of 13.7 cM between loci. The lb locus is located in a longer linkage group LG-2 and flanked by two markers, OP-Q5-1 and OP-M-2-2, at 9.3 cM and 15.9 cM, respectively. In the meantime, the RAPD loci, OP-Q5-2 and BC151, in a short linkage group were found to flank f at 13.7 cM and 13.4 cM, respectively. The construction of RAPD map has paved a way for further study of the genes for lateral branch, female sex expression and other agronomic traits in cucumber. | LIXiaozun PANJunsong WANGGang TIANLibo SILongting WUAizhong CAIRun | 2005 | Progress in Natural Science:Materials International2005，15，2： | 10 |
| 5 | A Novel System for Proliferation,Maintenance and Plantlet Germinationfrom Somatic Embryo of Soybean显示文摘Somatic embryogenesis was successfully induced with auxin in high concentration from immature cotyledons of 18genotypes of soybean(Glycin emax(L)Merr.)adaptable for planting in Northeast China.The frequency of somatic embryogenesis varied from 0.29%to77.62%among 18genotypes of soybean.The proliferative somatic embryos were obtained from 10genotypes of soybean at rate of 5.2%-22.1%.For the first time.plantlets were obtained even after subcultured and maintained on solid medium for over one year.This system provided a new and efficient receptor for genetic transformation of soybean. | WANGPing WANGGang JIJing WUYing | 2004 | Acta Botanica Sinica2004，46，2： | 8 |
| 6 | Capacity of soil to protect organic carbon and biochemical characteristics of density fractions in Ziwulin Haplic Greyxems soil显示文摘Physical protection is one of the important ways to stabilize organic carbon in soils. In order to under- stand the role of soils as a carbon sink or source in global climatic change and carbon cycles and properly manage soils as a carbon sink, we ought to know how many organic car- bon (OC) in a given soil could be protected. By a density fractionation approach and ultrasonic technique, each soil sample was divided into three fractions: free light fraction (free-LF), occluded fraction (occluded-LF) and heavy frac- tion (HF). The obtained fractions were analyzed for total OC content, carbohydrate content and recalcitrant OC content. The results showed: (ⅰ) In the whole soil profile, dominance of OC consistently decreased in the following order: HF, free-LF, occluded-LF. This suggested that OC in soils were mostly protected. From 0—10 to 60—80 cm horizons, the OC in free-LF decreased from 25.27% to 3.72%, while OC in HF they were increased from 72.57% to 95.39%. The OC in oc- cluded-LF was between 2.16% and 0.89%. (ⅱ) Organic carbon recalcitrance in free-LF was similar to that in HF, and was even higher than that in HF below the surface hori- zon. This suggested that free-LF was not always the most fresh and non-decomposed fraction. OM quality of HF was higher than that of free-LF in the surface 10 cm below, namely the protected OM had higher quality than free OM in these horizons. | WANGGang WANGChunyan WANGWenying WANGQiji | 2005 | Chinese Science Bulletin2005，50，1： | 7 |
| 7 | Ecophysiological Evidence for the Competition Strategy of Two Psammophytes Artemisia halodendron and A. frigida in Horqin Sandy Land, Nei Mongol显示文摘Gas exchange, water relations and leaf chemical characteristics were examined of twodominant psammophytes: Artemisia frigida Willd and A halodendron Turcz. ex Bess in Horqin sandy land, NeiMongol, China under different water regimes. The measurements were conducted by submitting the plantsto five different irrigation levels. A. fTigida was characterized by lower photosynthetic rate (Pn), lowertranspiration rate ( TR and lower shoot water potential (ψuw) relative to A. halodendron. Foliage of A frigdahad higher values of relative water deficit (RWD), bound water content (BWC), ratio of bound water contentto free water content (BWC/FWC) and integrated drought-resistant index (DI than that of A. halodendron.Water relations differed significantly between two species in response to soil water availability. ψw, BWCand BWC/FWC ratio of A halodendron exhibited large variation with gradual decrease of soil moisture.However, in terms of these parameters, A. fRIGIDA was characterized by higher capacity of water holding anddrought tolerance relative to A halodendron. Proline and total soluble sugar contents of A frigida and Ahalodendron tended to increase with decrease of soil moisture and the former had a larger increaseamplitude than the latter. This shows that A frigida has a higher osmotic regulation ability than A halodendron.Under the extreme drought conditions, ψw, RWD, BWC and BWC/FWC of two species were approximate,but soluble proteins degraded largely. A large amount of accumulation of organic matter, proline and totalsoluble sugars were observed in both A halodendron and A frigida. The increase in proline and total solublesugar contents and soluble protein degradation of A frigida far exceeded those of A. halodendron. Webelieve that the accumulated materials at this moment are mostly of nutrient substances available for therecovery of plants after the drought. This is one of the reasons why A halodendron plants died while Afrigida plants survived under extremely drought condition. Our results suggest that these ecophysiologicalfeatures of A frigida are favorable to its growth in the fixed sandy land compared with A halodendron, whichoften lost its dominance due to weak competition for water sources under lower soil water availability andare major factors resulting in replacement of A. halodendron by A. frigida in the later stage of sandyvegetation succession in Horqin. | ZHOUHai-Yan LISheng-Gong LIXin-Rong ZHAOAi-Fen ZHAOHa-Lin FANHeng-Wen WANGGang | 2004 | Acta Botanica Sinica2004，46，3： | 7 |
| 8 | APPROACH TO IMPROVEMENT OF ROBOT TRAJECTORY ACCURACY BY DYNAMIC COMPENSATION显示文摘Some dynamic factors, such as inertial forces and friction, may affect the robot trajectory accuracy. But these effects are not taken into account in robot motion control schemes. Dynamic control methods, on the other hand, require the dynamic model of robot and the implementation of new type controller. A method to improve robot trajectory accuracy by dynamic compensation in robot motion control system is proposed. The dynamic compensation is applied as an additional velocity feedforward and a multilayer neural network is employed to realize the robot inverse dynamics. The complicated dynamic parameter identification problem becomes a learning process of neural network connecting weights under supervision. The finite Fourier series is used to activate each actuator of robot joints for obtaining training samples. Robot control system, consisting of an industrial computer and a digital motion controller, is implemented. The system is of open architecture with velocity feedforward function. The proposed method is not model-based and combines the advantages of close-loop position control and computed torque control. Experimental results have shown that the method is validatities to improve the robot trajectory accuracy. | WangGang RenGuoli YanXiang'an WangGuodong | 2004 | Chinese Journal of Mechanical Engineering2004，17，3： | 5 |
| 9 | Effects of emodin on the proliferation of the glomerular mesangial cell and correlative cytokines in rats显示文摘客观: 在老鼠在房间增长和 glomerular mesangial 的关联词 cytokines 分泌物上调查 emodin (EMD ) 的效果。方法: 房间增长和 IL-6 上的 EMD 的效果, TGF- β在老鼠的 glomerular mesangial 的 1 分泌物被观察。房间增长被 MTT 方法测量。IL-6 和 TGF- β 1 分泌物与 ELISA 被检测。结果: EMD 能禁止房间增长和下面调整 IL-6 和 TGF- β glomerular mesangial 的 1 分泌物,作为与在老鼠的模型组相比(P < 0.05 ) 。结论: EMD 能显著地禁止房间增长,并且减少细胞外的矩阵(ECM ) 的创造,这显示它能在 glomerular 的缓和和预防起一个重要作用硬化。机制可以是 EMD 能减少 IL-6 和 TGF- β在老鼠的 glomerular mesangial 房间的 1 分泌物。 | Xili Wu Wanggang Zhang Wansen Sun Chenglin Qiao | 2007 | Journal of Nanjing Medical University2007，21，5： | 5 |
| 10 | Preparation of monoclonal antibody against human KIAA0100 protein and Northern blot analysis of human KIAA0100 gene显示文摘Monoclonal antibodies(MAbs) are important tools for the study of proteins′ function and structure. But there has been no report on the preparation of MAbs against human KIAA0100 protein up to date. Here, first, we generated the mouse MAb against human KIAA0100 protein using purified recombinant 6×Histidinc(6×His)-tagged human KIAA0100 protein segment(1557–2234) as an antigen; then, the m RNA expression of human KIAA0100 gene was detected in U937 cells using Northern blot analysis. The results showed that the mouse MAb against human KIAA0100 protein could sensitively recognize the human KIAA0100 protein using Western blot analysis and immunocytochemistry analysis. Besides, Western blot analysis revealed that human KIAA0100 gene possibly encoded two different protein products(254 k Da and < 250 k Da) in U937 cells. Moreover,Northern blot analysis confirmed that human KIAA0100 gene might produced two different m RNA products(6000–10000 bp and 5000–6000 bp) in U937 cells. The results provide a basis for large-scale production of the MAb against human KIAA0100 protein, which will be useful for the study of human KIAA0100 protein′s function/structure and MAb-targeted drugs in the future. | He Cui Xi Lan Shemin Lu Fujun Zhang Wanggang Zhang | 2017 | Journal of Pharmaceutical Analysis2017，7，3： | 4 |
| 11 | An effective rolling process of magnesium alloys for suppressing edge cracks: Width-limited rolling显示文摘To suppress the edge crack of the magnesium alloy sheet during the ordinary rolling process, a new rolling process named width-limited rolling was proposed in this paper. Width-limited rolling is a rolling method in which the width of the alloy sheet is limited by modifying the shape of the rollers, allowing a compressive stress field to form at the edge portion of the alloy sheet during rolling, resulting in the reduction of edge cracks. At present work, magnesium alloy sheets were separately subjected to ordinary rolling and width-limited rolling. The microstructure evolution and mechanical properties of the rolled sheets were investigated by EBSD, TEM, and XRD. The results exhibited that under the same rolling conditions, the sheet after ordinary rolling exhibited obvious edge cracks while no crack was found at the edge of the sheet after width-limited rolling. The edge crack suppressing effect was attributed to the reduction of the tensile stress along rolling direction during WLR, promoting the synchronous extension of the edge and center regions to suppress edge crack tendency. Microstructure observation showed that the compressive twins formed in the sheet after ordinary rolling usually exhibited as thin plates and cannot continue to fully develop due to the premature generation of the edge cracks. However, the compressive twins developed maturely in some of which double twins formed and various slip systems with different dislocation Burgers vectors occurred in the rolled sheet after WLR. More twin intersections and shear bands, providing more potential recrystallization nucleation sites, which are beneficial to weaken basal texture. With the cooperation of twinning and dislocation slip, the texture of the sheet after the width-limited rolling is weakened and the mechanical properties are improved. | Jing Tian Huihu Lu Wanggang Zhang Huihui Nie Quanxin Shi Jiafei Deng Wei Liang Lifei Wang | 2022 | Journal of Magnesium and Alloys2022，10，8： | 2 |
| 12 | 显示文摘 | WangGang(SE岗) LiHaihua(李海华) HuangZhongwei(黄宗伟)etal | 2009 | 稀有金属材料与工程2009，38，1： | 1 |
| 13 | 显示文摘 | LIUXiao-zhen WANGGang LIXin etal(刘小珍 王刚 李昕 等) | | 光谱学与光谱分析0，，： | 1 |
| 14 | Effects of mifepristone on the proliferation, apoptosis and cis-diamminedichloroplatinum sensitivity of cultured chemoresistant human ovarian cancer cells显示文摘Of late, more and more studies are being carried out to explore the anti-tumour activity of mifepristone. As Rose and Barnea 1 reported, mifepristone can inhibit the growth of cultured ovarian carcinoma cells. The role of mifepristone in cis-diamminedichloroplatinum (CDDP) and taxol resistant ovarian carcinoma was found in Rocereto and colleagues’ study. 2 The purpose of this study was to examine the effect of mifepristone on the growth and CDDP-sensitivity of CDDP-resistant human ovarian carcinoma cells and give an experimental basis for the treatment with mifepristone of refractory ovarian carcinoma. | WANGGang SHANGHui-ling XIEYong XIAOPing LIXiao-jie LINTie-cheng LIGuang-yi | 2005 | Chinese Medical Journal2005，，4： | 1 |
| 15 | 显示文摘 | WangGang(王刚) XuDongsheng(徐东生) YangRui(杨锐) | 2009 | 物理学报2009，58，1： | 1 |
| 16 | Theexpression and functional characterization associated withcell apoptosis and proteomic analysis of the novel geneMLAA-34 in U937 cells显示文摘 | Zhang Wenjuan Zhang Wanggang Zhang Pengyu | 2013 | Oncol Rep2013，29，2： | 1 |
| 17 | Quantitativeassessment of MLAA-34 expression in diagnosis and progno-sis of acute monocytic leukemia 显示文摘 | Zhao Jianqiang He Aili Zhang Wanggang | 2011 | Cancer Immunol Immu-nother2011，60，4： | 1 |
| 18 | 显示文摘 | WeiYuansheng(魏元生) WangGang(王刚) | 2015 | 汽车工艺与材料2015，12，： | 1 |
| 19 | Effects of Annealing Temperature on the Properties of Copper Films Prepared by Magnetron Sputtering显示文摘Copper oxide thin films were prepared by a direct-current magnetron sputtering method followed by a thermal annealing treatment at 100-500 °C. The obtained films were characterized by X-ray diffraction, UV–vis absorption spectroscopy, scanning electron microscopy, Raman spectroscopy, and X-ray photoelectron spectroscopy. With the increase of the annealing temperature, it was found that the films transformed sequentially from amorphous to single-phase Cu(100 ℃), mixed-phase of Cu and Cu2O(150 ℃), single-phase Cu2O(200 ℃), then to mixed-phase of Cu2 O and Cu O(300 ℃), and finally to single-phase Cu O(400- 500 ℃). Further analyses indicated that the Cu/Cu2 O thin films and the Cu2 O thin films presented no further oxidation even on the surface in air atmosphere. Additionally, the visible-light photocatalytic behavior of the copper oxide thin films on the degradation of methylene blue(MB) was also investigated, indicating that the films with pure Cu2 O phase or Cu/Cu2 O mixed phases have excellent photocatalytic efficiencies. | 刘一鸣 ZHANG Jianjun ZHANG Wanggang 梁伟 YU Bin XUE Jinbo | 2015 | Journal of Wuhan University of Technology(Materials Science)2015，30，1： | 1 |
| 20 | 高强度钢在汽车轻量化中的应用显示文摘 | WangGuangyong(王广勇) WangGang(王刚) | | 汽车工艺与材)0，，： | 1 |
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