|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | MicroRNA-125b Induces Cancer Cell Apoptosis Through Suppression of Bcl-2 Expression显示文摘MicroRNAs(miRNAs) are small,noncoding RNAs which can often act as an oncogene or a tumor suppressor.Several miRNAs are associated with the development of hepatocellular carcinoma(HCC).We demonstrated that miR-125b significantly suppresses HCC cell proliferation and promotes apoptosis by inhibiting the gene expression of the anti-apoptotic protein,Bcl-2.Bioinformatic analysis indicated that the 3'UTR of Bcl-2 has binding sites for miR-125b.Luciferase reporter assay confirmed the ability of miR-125b to dramatically suppress Bcl-2 transcription,suggesting that Bcl-2 is a target gene for miR-125b.We concluded that miR-125b acts as a tumor suppressor in hepatic tumor development by targeting Bcl-2 and inducing cancer cell apoptosis. | Aihua Zhao Quan Zeng Xiaoyan Xie Junnian Zhou Wen Yue Yali Li Xuetao Pei | 2012 | Journal of Genetics and Genomics2012，39，1： | 30 |
| 2 | Drift and deposition of pesticide applied by UAV on pineapple plants under different meteorological conditions显示文摘Spray drift has always been a focus research area in the field of unmanned aerial vehicle(UAV)application.Under the fixed premises of UAV operating parameters,such as height,speed and spraying liquid,the droplet drift is mainly affected by meteorological conditions.In this research,the spray drift and deposition tests were conducted using a QuanFeng120 UAV in a pineapple field under various different meteorological conditions.The experimental results showed that with the changes of UAV operating height and wind speed,the start position of the in-swath deposition area changed 4 m in the extreme situation.The percentage of the total spray drift was from 15.42%to 55.76%.The position of cumulative spray drift that accounted for 90%of the total spray drift was from 3.70 m to 46.50 m relative to the flight line.According to the downwind spray drift curve,the nonlinear equations of the same type under the four operating conditions of the UAV were fitted.The spray drift and the deposition of UAV application were significantly affected by different meteorological conditions and UAV operating heights.The results could provide a theoretical basis for UAV spraying in pineapple plants and support for spray drift control and prediction. | Juan Wang Yubin Lan Huihui Zhang Yali Zhang Sheng Wen Weixiang Yao Jiajian Deng | 2018 | International Journal of Agricultural and Biological Engineering2018，11，6： | 10 |
| 3 | Coupling Relationship Analysis on Households′ Production Behaviors and Their Influencing Factors in Nature Reserves:A Structural Equation Model显示文摘A households′production behavior directly influences the quality of the environment and determines the successful development of nature reserves.Meanwhile,the households′production behaviors are complicated by interrelated factors,such as protection attitudes,resource endowment,and family wealth.This research evaluated households near the Crested Ibis National Nature Reserve in Shaanxi Province,acquiring data from 436 households around Yang County and Ningshan County in the south slope of Qinling Mountains,China.Based on the collected data,we developed a structural equation model to evaluate the coupling relationships among households′ protection attitudes,production behaviors,resource endowment,and family wealth.The results showed that:1) households with great resource endowment had more negative attitudes,probably due to their greater protection costs;2) the households with higher education levels had worse protection attitudes;3) the households with more family wealth were likely to use fewer fertilizers,pesticides,and firewood;4) the households with more resource endowment showed less production and management behaviors;5) the enhancement of households' attitudes improved production behaviors to protection the environment,but the effects were not statistically significant.Our results provide a basis for the government's protection policy making,exploring the effective management measures that are beneficial for both nature reserve management and community development. | WANG Changhai WEN Yali DUAN Wei HAN Feng | 2013 | Chinese Geographical Science2013，23，4： | 6 |
| 4 | Evaluation of droplet deposition and effect of variable-rate application by a manned helicopter with AG-NAV Guía system显示文摘The variable-rate application is an important aspect of precision agriculture.In order to determine the regular patterns of droplet deposition and compare the actual variable-rate spraying effect of the AS350B3e helicopter with the AG-NAV Guía system,spray tests were conducted with different operating parameters and operating methods.In this study,the deposition distribution of droplets in the effective swath area was evaluated for six single-pass applications at four different flight velocities.The effects of adding adjuvant on droplet deposition,drift and droplet size were compared,and the actual variable effect of the forth-back application was verified.The analysis results showed that the position of the effective swath area was affected by natural wind velocity and wind direction,and would shift to the downwind direction area from the helicopter route of a different degree.The effective swath width increased slowly and then decreased sharply with the increase of flight velocity.It was found that flight velocity of 100 km/h was the peak inflection point of effective spray width variation.Moreover,the effect of flight velocity on the distribution uniformity of droplet deposition in the effective swath area was not significant.In the single-pass application of 90 km/h,adding adjuvant could increase droplet size in the effective swath area.The deposition increased by 8.98%,and the total drift decreased by 28.65%,of which the upwind drift decreased by 28.31%and the downwind drift decreased by 29.06%.In the forth-back application of 90 km/h,the error between actual application volume and system setting dose was 12%.The results of this study can provide valuable references for future research and practices on variable-rate aerial applications by manned helicopters. | Weixiang Yao Yubin Lan Sheng Wen Huihui Zhang Yali Zhang Juan Wang Chunchun Xie | 2019 | International Journal of Agricultural and Biological Engineering2019，12，1： | 6 |
| 5 | Effect of alkali-activation on aluminosilicate-based cementitious materials显示文摘High-performance aluminosilicate-based cementitious materials were produced with fly ash from a coal power plant as one of the major raw materials. The structures of fly ash containing aluminosilicate-based cementitious materials were compared be-fore and after treatment by the methods of nuclear magnetic resonance (NMR) and scanning electron microscopy (SEM). During the 28 d curing time, the compressive strength of water glass and fly ash samples increased from 9.08 MPa to 26.75 MPa. The results show that most of the stiff shells are destroyed after mechanical grinding and chemical activation. Magic angle spinning (MAS) NMR of 27Al shows that the wide peak becomes narrow and the main peak shifts to the direction of low field, indicating the decrease of polymerization degree, the enhancing of activity, the decrease of six-coordination structure, and the increase of small and symmet-rical four-coordination polyhedron structure within the aluminum-oxygen polyhedron network. Comparisons between MAS NMR of 29Si with different treatments suggest that Q0 disappears, the quantity of Q2 increases, and the quantity of Q4 decreases. The polym-erization degree of silicon-oxygen is reduced, and the potential activity of fly ash is increased. | Xiaoguang Yang Wen Ni Xufang Zhang Yali Wang | 2008 | Journal of University of Science and Technology Beijing2008，15，6： | 2 |
| 6 | Molecular phylogeny and historical biogeography of the cave fish genus Sinocyclocheilus(Cypriniformes:Cyprinidae)in southwest China显示文摘Modern accumulations of genetic data offer unprecedented opportunities for understanding the systematic classification and origins of specific groups of organisms.The genus Sinocyclocheilus is among the most cave abundant genera in Cyprinidae,with 76 recognized species,belonging to 4 species groups.Recent phylogenetic studies have shown that the classification of species groups within the genus Sinocyclocheilus remains controversial.In this study,we constructed a sequence supermatrix of 26 species from 4 species groups of the genus Sinocyclocheilus using the mitochondrial genome to reveal phylogenetic relationships,historical biogeography and patterns of species diversification in the genus Sinocyclocheilus.Phylogenetic analysis strongly supports the monophyletic groups of the 3 species groups(S.jii,S.cyphotergous,and S.tingi groups)except the S.angularis group.Phylogenetic analysis showed that S.anshuiensis and S.microphthalmus,which were recognized as numbers of S.angularis group,formed a strongly supported independent clade.Therefore,we propose a new species group,the S.microphthalmus group,which contains S.anshuiensis and S.microphthalmus.Biogeographic reconstruction suggests that the living Sinocyclocheilus may have originated in north-central Guangxi at the late Eocene and dispersed outward after a vicariance at 32.31 Million years ago(Ma).Early diversification is focused on the late Oligocene(ca.25 Ma),which is related to the second uplift of the Qinghai−Tibetan Plateau and the lateral extrusion of the Indochina at the Oligocene/Miocene boundary.Our results suggest that 2 uplifts of the Qinghai−Tibetan Plateau and climate change in the Miocene may have influenced the diversification of the Sinocyclocheilus lineage. | Huamei WEN Tao LUO Yali WANG Siwei WANG Tao LIU Ning XIAO Jiang ZHOU | 2022 | Integrative Zoology2022，17，2： | 2 |
| 7 | Re- cent changes in the summer precipitation pattern in east China and the background circulation 显示文摘 | ZHU Yali WANG Huijun ZHOU Wen | 2011 | Climate Dynamics2011，36，7： | 1 |
| 8 | Gastrospirillum hominis and Helicobacter pylori infection in Thai individuals:comparison of histopathological changes of gastric mucosa显示文摘 | Yali Z Yamada N Wen M | 1998 | Pathol Int1998，48，7： | 1 |
| 9 | Isolation and identification of endophytic fungus SX01, a red pigment producer from Ginkgo biloba L显示文摘 | Min Qiu Ruisheng Xie Yu Shi Haimin Chen Yali Wen Yongsheng Gao Xiufang Hu | 2010 | World Journal of Microbiology and Biotechnology2010，，6： | 1 |
| 10 | The global competitiveness of the Chinese wooden furniture industry显示文摘 | Xiao Han Yali Wen Shashi Kant | | 0，，11： | 1 |
| 11 | The Effects of the Sloping Land Conversion Program on Poverty Alleviation in the Wuling Mountainous Area of China显示文摘 | Duan Wei Lang Zhengxin Wen Yali | 2015 | SMALL-SCALE FORESTRY2015，14，3： | 1 |
| 12 | 大熊猫保护区的生态系统服务价值显示文摘文章简介全球生态系统服务价值估计每年为125万亿美元,相似的国家和区域层面的评估也显示生态系统服务价值足以支撑我们的生活。所有的生态系统服务价值评估都肯定了生物多样性的重要作用. | 魏辅文 Robert Costanza Qiang Dai Natalie Stoeckl Xiaodong Gu Stephen Farber Yonggang Nie Ida Kubiszewski Yibo Hu Ronald Swaisgood Xuyu Yang Michael Bruford Youping Chen Alexey Voinov Dunwu Qi Megan Owen Li Yan Daniel C.Kenny Zejun Zhang Rong Hou Shiwei Jiang Hongbo Liu Xiangjiang Zhan Li Zhang Biao Yang Lianjun Zhao Xiaoguang Zheng Wenliang Zhou Yali Wen Heran Gao Wen Zhang | 2019 | 科学新闻2019，0，2： | 1 |
| 13 | Role of epimorphin in bile duct formation of rat liver epithelial stem‐like cells: Involvement of small G protein RhoA and C/EBPβ显示文摘 | Yali Jia Hailei Yao Junnian Zhou Lin Chen Quan Zeng Hongfeng Yuan Lei Shi Xue Nan Yunfang Wang Wen Yue Xuetao Pei | 2011 | J Cell Physiol2011，，11： | 1 |
| 14 | Green accounting for forest and green policies in China — A pilot national assessment显示文摘 | Zhang Ying Minxue Gao Junchang Liu Yali Wen Weimin Song | 2011 | Forest Policy and Economics2011，，7： | 1 |
| 15 | An Economic Optimization Method for Demand-side Energy-storage Accident Backup Assisted Deep Peaking of Thermal Power Units显示文摘With the large-scale penetration of new energy such as wind power,its anti-modulation peak characteristics have increased challenges in power systems.Therefore,an economic optimization method for depth peak regulation and the depth of the emergency of the Energy storage(ES)accident on the demand side is proposed.First,a quantitative model of unplanned disconnection risk caused by weather state,load level,and fault type is constructed to obtain the spare and available ES capacity.Therefore,a deep peak regulation(DPR)economic optimization model is established to minimize the fuel injection cost of thermal power units,including ES accident standby,unit damage,and fuel demand.The particle swarm optimization algorithm is used to simulate the modified IEEE 30-node system.Based on the results,the DPR of ES accident standby can reduce the wind abandonment rate by 1.1%and the total peak adjustment cost by 33.5%under class-A weather.In class-C weather,the wind abandonment ratio can be reduced by 4.19%,reducing the cost of the total adjustment peak by 31.4%.The multiple purposes of improving the power grid modulation,wind power,and the standby utilization of ES accidents can be achieved. | Wen Wei Ze Ye Yali Wang Shuangfeng Dai Lei Chen Xiaolong Liu | 2022 | Chinese Journal of Electrical Engineering2022，8，2： | 0 |
| 16 | Empirical Analysis of Forest Pest Control Efficiency from 2003 to 2014 in China显示文摘Three indexes including forest pest occurrence area,control area and input fund of 31 provinces from 2003 to 2014 were selected from Forestry Statistical Yearbook,to establish dynamic interaction index evaluation system with clustering robust regression model and Stata 13. 0 software. Total forest pest control efficiency in China was determined according to the computing result of entropy method. Suggestions such as improving forest pest control efficiency,increasing service efficiency and input amount of forest pest control input funds were put forward. It will provide empirical basis for target management evaluation of forest pest control work and accountability system. | Cai Qi Cai Yushi Sun Shibo Ding Huimin Ren jie Wen Yali | 2017 | Plant Diseases and Pests2017，8，5： | 0 |
| 17 | A preliminary experimental investigation on the biotribocorrosion of a metal-on-polyethylene hip prosthesis in a hip simulator显示文摘Corrosion at the taper/trunnion interface of total hip replacement(THR)often results in severe complications.However,the underlying mechanisms of biotribocorrosion at the taper/trunnion interface during the long-term walking gait cycles remain to be fully understood.In this study,a hip joint simulator was therefore instrumented with an electrochemical cell for in-situ monitoring of the tribocorrosion evolution in a metal-on-polyethylene(MoP)THR during a typical long-term walking gait.In addition,the biotribocorrosion mechanism was investigated via surface and chemical characterizations.The experimental results confirmed that the taper/trunnion interface dominated the contemporary MoP hip joint corrosion.Three cyclic variations in the open circuit potential(OCP)were observed throughout the long-term electrochemical measurements,attributed to the formation and disruption of the adsorbed protein layer.The corrosion exhibited an initial increase at each period,peaking at approximately 0.125 million cycles,followed by a subsequent gradual reduction.Surface and chemical analyses revealed the formation of a tribochemical reaction layer(tribolayer)on the worn surface of the taper/trunnion interface.The surface/chemical characterizations and the electrochemical measurements indicated that the adhesion force of the adsorbed protein layer was weaker than that of the tribolayer.In contrast,the opposite was true for the corrosion resistance.Based on the observations from this study,the tribocorrosion mechanism of the taper/trunnion interface under the long-term walking gait cycles is deduced. | Shu YANG Jian PU Xiaogang ZHANG Yali ZHANG Wen CUI Fengbao XIE Weiping LU Qin TAN Zhongmin JIN | 2023 | Friction2023，11，6： | 0 |
| 18 | Electrochemically-induced highly reactive PdO^(*) interface on modulated mesoporous MOF-derived Co_(3)O_(4) support for selective ethanol electro-oxidation显示文摘Herein,Pd nanoparticles loaded Co_(3)O_(4)catalysts(Pd@Co_(3)O_(4))are constructed from zeolitic imidazolate framework-67(ZIF-67)for the ethanol oxidation reaction(EOR).It is demonstrated for the first time that the electrochemical conversion of Co_(3)O_(4)support would result in the charge distribution alignment at the Pd/Co_(3)O_(4)interface and induce the formation of highly reactive Pd-O species(PdO^(*)),which can further catalyze the consequent reactions of the intermediates of the ethanol oxidation.The catalyst,Pd@Co_(3)O_(4)-450,obtained under the optimized conditions exhibits excellent EOR performance with a high mass activity of 590 mA mg-1,prominent operational stability,and extraordinary capability for the electro-oxidation of acetaldehyde intermediates.Importantly,the detailed mechanism investigation reveals that Pd@Co_(3)O_(4)-450 could be benefit to the C-C bond cleavage to promote the desirable C1 pathway for the ethanol oxidation reaction.The present strategy based on the metal-support interaction of the catalyst might provide valuable inspiration for the design of high-performing catalysts for the ethanol oxidation reaction. | Yuling Chen Yali Wen Qun Zhou Lina Shen Fanghui Du Pai Peng Yu Chen Junwei Zheng | 2023 | Journal of Energy Chemistry2023，，11： | 0 |
| 19 | The LncRNA FEZF1-AS1 promotes tumor proliferation in colon cancer by regulating the mitochondrial protein PCK2显示文摘LncRNAs and metabolism represents two factors involved in cancer initiation and progression.However,the interaction between lncRNAs and metabolism remains to be fully explored.In this study,lncRNA FEZF1-AS1(FEZF1-AS1)was found upregulated in colon cancer after screening all the lncRNAs of colon cancer tissues deposited in TCGA,the result of which was further confirmed by RNAscope staining on a colon tissue chip.The results obtained using FEZF1-AS1 knockout colon cancer cells(SW480 KO and HCT-116 KO)constructed using CRISPR/Cas9 system confirmed the proliferation,invasion,and migration-promoting function of FEZF1-AS1 in vitro.Mechanistically,FEZF1-AS1 associated with the mitochondrial protein phosphoenolpyruvate carboxykinase(PCK2),which plays an essential role in regulating energy metabolism in the mitochondria.Knockdown of FEZF1-AS1 greatly decreased PCK2 protein levels,broke the homeostasis of energy metabolism in the mitochondria,and inhibited proliferation,invasion,and migration of SW480 and HCT-116 cells.PCK2 overexpression in FEZF1-AS1 knockout cells partially rescued the tumor inhibitory effect on colon cancer cells both in vitro and in vivo.Moreover,PCK2 overexpression specifically rescued the abnormal accumulation of Flavin mononucleotide(FMN)and succinate,both of which play an important role in oxidative phosphorylation(OXPHOS).Overall,these results indicate that FEZF1-AS1 is an oncogene through regulating energy metabolism of the cell.This research reveals a new mechanism for lncRNAs to regulate colon cancer and provides a potential target for colon cancer diagnosis and treatment. | HUAMIN WANG YANTING WU ZHENLEI WANG YUHANG CHEN JINYU MO WEN GUAN YALI ZHANG HONGLIANG YAO | 2021 | Oncology Research2021，29，3： | 0 |
| 20 | Performance improvement of air-breathing proton exchange membrane fuel cell(PEMFC) with a condensing-tower-like curved flow field显示文摘Air-breathing proton exchange membrane fuel cells(PEMFCs) are very promising portable energy with many advantages. However, its power density is low and many additional supporting parts affect its specific power. In this paper, we aim to improve the air diffusion and fuel cell performance by employing a novel condensing-tower-like curved flow field rather than an additional fan, making the fuel cell more compact and has less internal power consumption. Polarization curve test and galvanostatic discharge test are carried out and proved that curved flow field can strengthen the air diffusion into the PEMFC and improve its performance. With appropriate curved flow field, the fuel cell peak power can be 55.2%higher than that of planar flow field in our study. A four-layer stack with curved cathode flow field is fabricated and has a peak power of 2.35 W(120 W/kg). | Hanqing Jin Siyi Zou Qinglin Wen Yali Li Fandi Ning Pengpeng Xu Saifei Pan Xiaochun Zhou | 2023 | Chinese Chemical Letters2023，34，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员