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| 1 | Effects of plant species coexistence on soil enzyme activities and soil microbial community structure under Cd and Pb combined pollution显示文摘The relationship between plant species coexistence and soil microbial communities under heavy metal pollution has attracted much attention in ecology.However,whether plant species coexistence could offset the impacts of heavy metal combined pollution on soil microbial community structure and soil enzymes activities is not well studied.The modified ecological dose model and PCR-RAPD method were used to assess the effects of two plant species coexistence on soil microbial community and enzymes activities subjected to Cd and Pb combined stress.The results indicated that monoculture and mixed culture would increased microbe populations under Cd and Pb combined stress,and the order of sensitivity of microbial community responding to heavy metal stress was:actinomycetes > bacteria > fungi.The respirations were significantly higher in planted soil than that in unplanted soil.The plant species coexistence could enhance soil enzyme activities under Cd and Pb combined.Furthermore,planted soil would be helpful to enhance soil genetic polymorphisms,but Cd and Pb pollution would cause a decrease on soil genetic polymorphisms.Mixed culture would increase the ecological dose 50%(ED50) values,and the ED50 values for soil enzyme activities decreased with increasing culture time.The dehydrogenase was most sensitive to metal addition and easily loses activity under low dose of heavy metal.However,it was difficult to fully inhibit the phoshpatase activity,and urease responded similarly with phosphatase. | Yang Gao Pei Zhou Liang Mao Yueer Zhi Chunhua Zhang Wanjun Shi | 2010 | Journal of Environmental Sciences2010，22，7： | 19 |
| 2 | MicroRNA-663 induces immune dysregulation by inhibiting TGF-β1 production in bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus显示文摘Mesenchymal stem cells(MSCs)are critical for immune regulation.Although several microRNAs(miRNAs)have been shown to participate in autoimmune pathogenesis by affecting lymphocyte development and function,the roles of miRNAs in MSC dysfunction in autoimmune diseases remain unclear.Here,we show that patients with systemic lupus erythematosus(SLE)display a unique miRNA signature in bone marrow-derived MSCs(BMSCs)compared with normal controls,among which miR-663 is closely associated with SLE disease activity.MiR-663 inhibits the proliferation and migration of BMSCs and impairs BMSC-mediated downregulation of follicular T helper(Tfh)cells and upregulation of regulatory T(Treg)cells by targeting transforming growth factorβ1(TGF-β1).MiR-663 overexpression weakens the therapeutic effect of BMSCs,while miR-663 inhibition improves the remission of lupus disease in MRL/lpr mice.Thus,miR-663 is a key mediator of SLE BMSC regulation and may serve as a new therapeutic target for the treatment of lupus. | Linyu Geng Xiaojun Tang Kangxing Zhou Dandan Wang Shiying Wang Genhong Yao Weiwei Chen Xiang Gao Wanjun Chen Songtao Shi Nan Shen Xuebing Feng Lingyun Sun | 2019 | Cellular & Molecular Immunology2019，16，3： | 16 |
| 3 | A subset of IL-17+ mesenchymal stem cells possesses anti-Candida albicans effect显示文摘骨头髓间充质的干细胞(MSC ) 与深刻 immunomodulatory 性质包括出生后的祖先房间的一张异构的人口,例如 Foxp3 + 的 upregulation 规章的 T 房间(Tregs ) 和 Th17 房间的 downregulation。然而,它是未知的是否不同 MSC subpopulations 拥有 immunomodulatory 的一样的范围功能。这里,我们证明生产 IL-17 的单个导出殖民地的 MSC 的一个子集与体积 MSC 人口不同因为它不能 upregulate Tregs, downregulate Th17 房间,或改善在一只大肠炎老鼠的疾病显型当模特儿。机械学地,我们揭示那 IL-17,由这些 MSC 生产了,激活 NFκ B 小径到 downregulate TGF-β在 MSC 的生产,导致基于 MSC 的 immunomodulation 的废除。而且,我们显示出那 NFκ B 能直接绑在 TGF-β倡导者区域将调整 TGF-β在 MSC 的表示。而且,这些 IL-17 + MSC 在 C 在 vitro 和治疗学的效果拥有 anti-Candida albicans 生长效果。感染 albicans 的老鼠。在摘要,这研究证明 MSC 包含能够禁止 C 的一个 IL-17 + 子集。albicans 生长,而是 attenuating 经由 NFκ 的基于 MSC 的免疫力的抑制; TGF-β 的调停 B 的 downregulation;。 | Ruili Yang Yi Liu Peyman Kelk Cunye Qu Kentaro Akiyama Chider Chen Ikiru Atsuta WanJun Chen Yanheng Zhou Songtao Shi | 2013 | Cell Research2013，23，1： | 8 |
| 4 | Lipid Distribution in Marine Sediments from the Northern South China Sea and Association with Gas Hydrate显示文摘The distributions of lipids in surface and subsurface sediments from the northern South China Sea were determined. The n-alkanes were in bimodal distribution that is characterized by a centre at n-C16 –n-C20 with maximum at C18(or C19) and n-C27 –n-C31 as well as at C29(or C31). The short-chain alkanes suffered from significant losses due to their slow deposition in the water column, and their presence with a slight even carbon predominance in shallow seafloor sediments was ascribed mainly to the direct input from the benthos. The long-chain alkanes with odd predominance indicate transportion of terrigenous organic matter. Immature hopanoid biomarkers reflect the intense microbial activity for bacteria–derived organic matter and the gradual increase of maturity with burial depth. Abundant n-fatty acid methyl esters(n-FAMEs) that are in distributions coincident with fatty acids were detected in all samples. We proposed that the observed FAMEs originated from the methyl esterification of fatty acids; methanol production by methanotrophs and methanogenic archaea related to the anaerobic oxidation of methane, and sulfate reduction provided an O–methyl donor for methylation of fatty acids. The CH4 released from hydrate dissociation at oxygen isotope stage II of Cores ZD3 and ZS5, which had been confirmed by the occurrence of negative δ13C excursion and spherical pyrite aggregates, could have accelerated the above process and thus maximized the relative content of FAMEs at ZD3-2(400–420 cm depth) and ZS5-2(241–291 cm depth). | OU Wenjia LEI Huaiyan LU Wanjun ZHANG Jie SHI Chunxiao GONG Chujun HAN Chao | 2014 | Acta Geologica Sinica(English Edition)2014，88，1： | 4 |
| 5 | Mesenchymal-Stem-Cell-Induced Immunoregulation Involves FAS-Ligand-/FAS-Mediated T Cell Apoptosis显示文摘 | Kentaro Akiyama Chider Chen DanDan Wang Xingtian Xu Cunye Qu Takayoshi Yamaza Tao Cai WanJun Chen Lingyun Sun Songtao Shi | 2012 | Cell Stem Cell2012，，5： | 2 |
| 6 | Stability analysis of digitally controlled dual active bridge converters显示文摘The dual active bridge(DAB) converters are widely used in the energy storage equipment and the distributed power systems. However, the existence of switching nonlinearity and control delay can cause serious stability problem to the DAB converters. Thus, this paper,studies the stability of a digitally controlled DAB converter with an output voltage closed loop controller. Firstly, to accurately study the stability in a DAB converter, a discrete-time model established in a whole switching period is obtained. The model considers the output capacitor ESR,the digital control delay, and sample-and-hold process. By using this model, the stabilities of the DAB converter versus the proportional controller parameter and the output capacitor ESR are analyzed and the critical values are predicted accurately. Moreover, the stability boundary ofthe proportional controller parameter and the output capacitor ESR is also obtained. The result shows that the value of the output capacitor ESR can have a great effect on the stability region of the proportional controller parameter. Finally, the theoretical analyses are verified by the simulation and experimental results. | Ling SHI Wanjun LEI Zhuoqiang LI Yao CUI Jun HUANG Yue WANG | 2018 | Journal of Modern Power Systems and Clean Energy2018，6，2： | 1 |
| 7 | Continuous culture of urine-derived bladder cancer cells for precision medicine显示文摘Dear Editor,Bladder cancer is the most common type of genitourinary cancer in China,with an estimated 80,500 new cases and 32,900 related deaths in 2015 alone(Chen et al.,2016).Unlike many other cancers,there has been no significant improvement in survival rates for bladder cancer over the last three decades.Specific treatment regimens for bladder cancer and their efficacy vary depending not only on clinical stages,but also on associated risk factors and other personal clinical characteristics.Patients with non-muscle invasive bladder cancer(NMIBC)have a high 5-year recurrence rate of 60%-70%(Berdik,2017)and those with muscle invasive bladder cancer(MIBC)has a relatively poor prognosis with approximately 65%risk of death within 5-year follow-up(Kamat et al.,2016).Therefore,there is an urgent need to develop models for bladder cancer to screen for rational treatment strategies by personalized medicine to improve the clinical assessment and treatment of bladder cancer. | Shuai Jiang Jiaqi Wang Chen Yang Renke Tan Jun Hou Yuan Shi Huihui Zhang Shiyu Ma Jianan Wang Mengmeng Zhang George Philips Zengxia Li Jian Ma Wanjun Yu Guohua Wang Yuanming Wu Richard Schlegel Huina Wang Shanbo Cao Jianming Guo Xuefeng Liu Yongjun Dang | 2019 | Protein & Cell2019，10，12： | 1 |
| 8 | Pseudo-polar drive patterns for brain electrical impedance tomography显示文摘 | Shi Xuetao Dong Xiuzhen Shuai Wanjun | 2006 | Physiol Meas2006，27，： | 1 |
| 9 | Management of Lisfranc injury with anterolateral calcaneal compression fracture显示文摘To the Editor:The mechanism of Lisfranc injury is complex and may cause different patterns of fractures or dislocation of the midfoot complex.Abduction force injury is a special injury pattern,which may cause the fracture or(and)dislocation of the lateral column of the Lisfranc joint,especially the cuboid.[1,2,3]However,the anterolateral calcaneus is less commonly involved.Since the fragment of the calcaneocuboid(CC)joint facet is too uncon-spicuous to manifest on a plain X-ray,and surgeons always pay more attention to the Lisfranc joint,anterolateral calcaneal compression fracture and even Chopart joint injuries are often overlooked,which may lead to a delayed surgical management,chronic foot deformities,and functional disability. | Wenqi Gu Rui Zhang Wanjun Liu Zhongmin Shi Guohua Mei Jianfeng Xue Jian Zou Xiaokang Wang Jiantao Jiang | 2022 | Chinese Medical Journal2022，，6： | 1 |
| 10 | Pseudo-polar drive patterns for brain electrical impedance tomography显示文摘 | Shi Xuetao Dong Xiuzhen Shuai Wanjun | 2006 | Physiol Meas2006，27，： | 1 |
| 11 | Expert consensus on the prevention and treatment of substance use and addictive behaviour-related disorders during the COVID-19 pandemic显示文摘In early 2020,the COVID-19 outbreak complicated the diagnosis,treatm ent and rehabilitation of patients with substance use disorders and increased the risks of substance abuse and addictive behaviours,such as online gaming disorders,in the general public.Substance use disorder is a chronic recurrent brain disease characterised by strong cravings,high recurrence rates,and a high proportion of comorbidity of mental and physical disorders.1 Therefore,regular long-term therapeutic interventions are critical to preventing dm g relapses while maintaining withdrawal. | Jiang Du Ni Fan Min Zhao Wei Hao Tieqiao Liu Lin Lu Jie Shi Haifeng Jiang Na Zhong Xiaochang Lan Shichao Xu Hongxian Chen Xiaojun Xiang Xuyi Wang Hongqiang Sun Bing Li Yu-Ping Ning Jing Li Wanjun Guo Yajuan Niu Lixia Sheng Yi Li Xuebin Liu Xuhui Zhou Mincai Qian Wenhua Zhou Ruiling Zhang Hongxing Hu Yan Xia Zhonghua Su Ruimin Zhang Mei Yang Fen Liu Wei Yuan | 2020 | General Psychiatry2020，33，4： | 1 |
| 12 | Pseudo-polar drive patterns for brain electrical impedance tomography显示文摘 | Shi Xuetao Dong Xiuzhen Shuai Wanjun | 2006 | Physiol Meas2006，27，： | 1 |
| 13 | NUMERICAL SIMULATION ON DEFORMATION CHARACTERISTICS OF AS WIRE BY CASTEX显示文摘Castex(continuous cast and extrusion)is a latest metallurgical technology Making of AS wire(aluminum clad steel wire) by Castex is an advanced bonding technology of bimetal In order to study the deformation character of AS wire the numerical simulation is performed with FE method From the simulation result the following conclusions are obtained:① The simulation is carried out sequentially in three zones:initial extrusion,cavity filling and bonding ② In the first zone the shearing deformation governs the whole zone,while in that of cavity filling, the deformation mainly concentrates on transition arc of the concave mould In addition, in the last zone, the dominant deformation lies at the boundary of concave mould, surface of steel wire and entry of sizing band Due to the movement of steel wire, the direction of shear stress on its surface is opposite to that on the boundary of concave | Shi Zhiyuan Wang Wanjun Wang Xinhua Metallurgical Engineering School,Beijing University of Science and Technology Wen Jinglin Northeastern University | 2001 | Chinese Journal of Mechanical Engineering2001，14，1： | 0 |
| 14 | Experiment Study on Castex Process of AS Wire显示文摘In order to optimize the Castex process of AS wire, the systematic experiments have been done for differed process parameters with self-made DZJ-II 350 Castex machine. The parameters, such as casting temperature of aluminum, flow of cooling Water, extrusion ratio and the gap between the surface of wheel and that of the mould, have been mainly studied. The results show that with the increase of casting temperature or rotating speed of wheel the measured length of liquid metal zone increases too. However, the length of liquid metal zone decreases with the increase of the flow of cooling water Moreover, the relationship between the extrusion ratio and the extrusion power is studied. | Zhiyuan Shi Wanjun Wang Jinglin Wen Xinhua Wang Metallurgy School, University of Science and Technology Beijing, Beijing 100083, China School of Materials and Metallurgy,Northeastern University, Shenyang 110006, China | 2001 | Journal of University of Science and Technology Beijing2001，8，1： | 0 |
| 15 | Feasible fabrication of o-phenanthroline-based polymer adsorbent for selective capture of aqueous Ag(Ⅰ)显示文摘Devising a desirable adsorbent for efficiently selective capture of Ag(Ⅰ) from wastewater has attracted much attention but faced with huge challenges. Herein, a novel linear o-phenanthroline-based polymer L-PRL was prepared via chemical oxidative polymerization for the adsorption of Ag(Ⅰ). The maximum adsorption capacity for Ag(Ⅰ) by L-PRL is 325.8 mg/g at pH 0. In addition, L-PRL owes ascendant selectivity for Ag(Ⅰ) from aqueous solutions containing various interfering metal ions of Pb(Ⅱ), Co(Ⅱ), Ni(Ⅱ), Cd(Ⅱ)and Fe(Ⅲ). Multiple characterizations of FT-IR and XPS uncover that the N groups on L-PRL act as adsorption sites to coordinate with Ag(Ⅰ). Density functional theory(DFT) calculations further evidence the mechanism that L-PRL is provided with the admirable adsorptivity and selectivity for Ag(Ⅰ). It is mainly attributed to the most stable complexes of L-PRL with Ag(Ⅰ), which possesses shortest Ag-N bond length compared with other heavy metal ions. Furthermore, 93.5% of initial adsorption capacity is reserved after four continuous regeneration cycles, indicating that L-PRL is equipped with superior recyclability and durability, and L-PRL is capable of removing Ag(Ⅰ) in low-concentration actual Ag(Ⅰ)-containing wastewater completely. This study shed light on the rational design of polymer adsorbents and in-depth insight into selective removal of aqueous Ag(Ⅰ). | Xuan Ding Wanjun Yu Xin Sheng Hui Shi Deng You Mingming Peng Penghui Shao Liming Yang Lingling Liu Xubiao Luo | 2023 | Chinese Chemical Letters2023，34，3： | 0 |
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