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| 1 | Is 1.28 parts per million biomarker specific for neural progenitor cells?显示文摘Nuclear magnetic resonance-visible mobile lipid,at 1.28 parts per million(ppm),is thought to be due to mobile lipid droplets formed in cells and has been considered unique for neural progenitor cells.However,this idea remains controversial.The present study examined the 1.28 ppm biomarker in other stem cells and non-stem cells,and explored the relationship between 1.28 ppm biomarker and mobile lipid droplets.1H nuclear magnetic resonance spectroscopy of EC109 cells,mesenchymal stem cells(MSCs) and adipogenic cells differentiated from MSCs was performed.Results show that 1.28 ppm biomarker was observed in human MSCs,but was absent from EC109 cells.Following adipogenic differentiation induced for 2 weeks,the 1.28 ppm biomarker climbed remarkably,with mobile lipid droplet generation,suggesting that the 1.28 ppm biomarker is not specific for neural progenitor cells because it is also observed in MSCs and adipogenic-induced differentiated cells.Moreover,it is possible to monitor MSCs differentiation following cell transplantation,using 1.28 ppm biomarker changes. | Zhifeng Xu Chongyang Shen Haiqiang Zhu Yaowen Chen Linping Wu Peng Huang YeyuXiao Zhiwei Shen Li Pang Xiuqin Guo Lian Ma Renhua Wu | 2010 | Neural Regeneration Research2010，5，15： | 2 |
| 2 | Effects of Mn on Microstructures and Properties of Hot Rolled Low Carbon Bainitic Steels显示文摘Two kinds of Mn-Si-Mo low carbon steels were designed to study the effects of Mn on the microstructures and properties of hot rolled low carbon bainitic steels.To reduce the production cost,a very low Mo content of 0.13%was added in both steels.After hot rolling,the mechanical properties of samples were tested.Microstructure was observed and analyzed by optical microscope and transmission electron microscope.The results show that the strength of tested steels increases with the increase in Mn content,while the elongation decreases.When Mn content increases,the bainite microstructure increases.The results can provide a theoretical basis for composition design and industrial production of low cost low carbon bainitic steels. | 王敏 徐光 WANG Li XU Yaowen XUE Zhengliang | 2017 | Journal of Wuhan University of Technology(Materials Science)2017，32，1： | 1 |
| 3 | Prediction model for the austenite grain growth in a hot rolled dual phase steel显示文摘 | XU Yaowen TANG Di SONG Yong | 2012 | Materials and Design2012，36，1： | 1 |
| 4 | Ultrafine Fe/Fe3C decorated on Fe-N_(x)-C as bifunctional oxygen electrocatalysts for efficient Zn-air batteries显示文摘Efficient bifunctional oxygen electrocatalysts for ORR and OER are fundamental to the development of high performance metal-air batteries.Herein,a facile cost-efficient two-step pyrolysis strategy for the fabrication of a bifunctional oxygen electrocatalyst has been proposed.The efficient non-preciousmetal-based electrocatalyst,Fe/Fe_(3)C@Fe-N_(x)-C consists of highly curved onion-like carbon shells that encapsulate Fe/Fe_(3)C nanoparticles,distributed on an extensively porous graphitic carbon aerogel.The obtained Fe/Fe_(3)C@Fe-N_(x)-C aerogel exhibited superb electrochemical activity,excellent durability,and high methanol tolerance.The experimental results indicated that the assembly of onion-like carbon shells with encapsulated Fe/Fe_(3)C yielded highly curved carbon surfaces with abundant Fe-Nxactive sites,a porous structure,and enhanced electrocatalytic activity towards ORR and OER,hence displaying promising potential for application as an air cathode in rechargeable Zn-air batteries.The constructed Zn-air battery possessed an exceptional peak power density of~147 mW cm^(-2),outstanding cycling stability(200 cycles,1 h per cycle),and a small voltage gap of 0.87 V.This study offers valuable insights regarding the construction of low-cost and highly active bifunctional oxygen electrocatalysts for efficient air batteries. | Lingbo Zong Xin Chen Siliang Liu Kaicai Fan Shuming Dou Jie Xu Xiaoxian Zhao Wenjun Zhang Yaowen Zhang Weicui Wu Fenghong Lu Lixiu Cui Xiaofei Jia Qi Zhang Yu Yang Jian Zhao Xia Li Yida Deng Yanan Chen Lei Wang | 2021 | Journal of Energy Chemistry2021，30，5： | 1 |
| 5 | “Reinforced concrete”-like flexible transparent electrode for organic solar cells with high efficiency and mechanical robustness显示文摘Flexible transparent electrodes(FTEs) with robust mechanical stability are crucial for the industrial application of flexible organic solar cells(OSCs). However, their production remains challenging owing to the difficulty in balancing the conductivity,transmittance, and adhesion of FTEs to substrates. Herein, we present the so-called “reinforced concrete” strategy which finetunes the structure of silver nanowires(Ag NWs)-based FTEs with polydopamine(PDA) possessing good adhesion properties and moderate reducibility. The PDA reduces Ag+to form silver nanoparticles(Ag NPs) which grow like “rivets” at the Ag NW junction sites;PDA stabilizes the Ag NW skeleton and improves the adhesion between the Ag NWs and polyethylene terephthalate(PET) substrate and interface layer. The obtained Ag NW:PDA:Ag NP FTE exhibits excellent optoelectronic properties and high mechanical stability. The resulting flexible OSCs exhibit 17.07% efficiency, high flexibility during 10,000 bending test cycles, and robust peeling stability. In addition, this “reinforced concrete”-like FTE provides great advantages for the production of large-area flexible OSCs, thereby paving a new way toward their commercial application. | Yang Chen Juanyong Wan Guiying Xu Xiaoxiao Wu Xinqi Li Yunxiu Shen Fu Yang Xuemei Ou Yaowen Li Yongfang Li | 2022 | Science China Chemistry2022，65，6： | 1 |
| 6 | Co‑packaged optics(CPO):status,challenges,and solutions显示文摘Due to the rise of 5G,IoT,AI,and high-performance computing applications,datacenter trafc has grown at a compound annual growth rate of nearly 30%.Furthermore,nearly three-fourths of the datacenter trafc resides within datacenters.The conventional pluggable optics increases at a much slower rate than that of datacenter trafc.The gap between application requirements and the capability of conventional pluggable optics keeps increasing,a trend that is unsustainable.Copackaged optics(CPO)is a disruptive approach to increasing the interconnecting bandwidth density and energy efciency by dramatically shortening the electrical link length through advanced packaging and co-optimization of electronics and photonics.CPO is widely regarded as a promising solution for future datacenter interconnections,and silicon platform is the most promising platform for large-scale integration.Leading international companies(e.g.,Intel,Broadcom and IBM)have heavily investigated in CPO technology,an inter-disciplinary research feld that involves photonic devices,integrated circuits design,packaging,photonic device modeling,electronic-photonic co-simulation,applications,and standardization.This review aims to provide the readers a comprehensive overview of the state-of-the-art progress of CPO in silicon platform,identify the key challenges,and point out the potential solutions,hoping to encourage collaboration between diferent research felds to accelerate the development of CPO technology. | Min Tan Jiang Xu Siyang Liu Junbo Feng Hua Zhang Chaonan Yao Shixi Chen Hangyu Guo Gengshi Han Zhanhao Wen Bao Chen Yu He Xuqiang Zheng Da Ming Yaowen Tu Qiang Fu Nan Qi Dan Li Li Geng Song Wen Fenghe Yang Huimin He Fengman Liu Haiyun Xue Yuhang Wang Ciyuan Qiu Guangcan Mi Yanbo Li Tianhai Chang Mingche Lai Luo Zhang Qinfen Hao Mengyuan Qin | 2023 | Frontiers of Optoelectronics2023，16，1： | 1 |
| 7 | Nuclear magnetic resonance spectroscopy is highly sensitive for lipid-soluble metabolites显示文摘Although the water-soluble metabolite profile of human mesenchymal stem cells is known,the lipid profile still needs further investigation.In this study,methanol-chloroform was used to extract lipid-soluble metabolites and perchloric acid was used to extract water-soluble metabolites.Furthermore,a dual phase extraction method using methanol-chloroform and water was used to obtain both water and lipid fractions simultaneously.All metabolite extractions were analyzed on a 9.4T high-resolution nuclear magnetic resonance spectrometer.Metabolite resonance peaks were assigned in the acquired spectra according to the chemical shift,and the extraction efficiency of different methods was compared.Results showed that in the spectra of water-soluble extracts,major metabolites comprised low molecular weight metabolites,including lactate,acetic acid,fatty acids,threonine,glutamic acid,creatine,choline and its derivatives,while in the spectra of lipid-soluble extracts,most metabolites were assigned to fatty acids.Among the different extraction procedures,perchloric acid was more efficient in extracting water-soluble metabolites and methanol-chloroform was efficient in extracting organic components compared with the dual phase extraction method.Nuclear magnetic resonance spectroscopy showed that as low as 0.7 mg organic yield was enough to obtain clear resonance peaks,while about 6.0 mg water-soluble yield was needed to obtain relatively favorable spectral lines.These results show that the efficiency of extracting water and lipid fractions is higher using perchloric acid and methanol-chloroform compared with dual phase extraction and that nuclear magnetic resonance spectroscopy is highly sensitive for analyzing lipid-soluble extracts. | Haiyang Dai Bikai Hong Zhifeng Xu Lian Ma Yaowen Chen Yeyu Xiao Renhua Wu | 2013 | Neural Regeneration Research2013，8，22： | 1 |
| 8 | Community Structure and Value Evaluation of Local Brassicaceae Potherbs in Shiyan City显示文摘[Objectives]This study was conducted to evaluate the value of local Brassicaceae potherb resources in Shiyan City.[Methods]Seven species of local Brassicaceae edible plants resources in Shiyan City,including Cardamine hirsuta L.,Cardamine flexuosa,Cardamine impatiens L.,Capsella bursa-pastoris(Linn.),Orychophragmus violaceus(L.)O.E.Schulz,Draba nemorosa L.,Rorippa indica(L.)Hiern.,were investigated using sampling method,and their value was evaluated.[Results]①Shiyan City was rich in resources of local Brassicaceae potherbs,mostly of which grew in humid areas.②In the communities of target species,there were 20 species of plants in 19 genera of 15 families in the arbor layer,19 species of plants in 16 genera from 15 families in the shrub layer,and 58 species of plants in 51 genera from 23 families in the herbaceous layer.The tree,shrub and herb species with the highest dominance Populus simonii var.przewalskii,Robinia pseudoacacia and Chrysanthemum indicum.Local Brassicaceae potherbs in Shiyan City have high edible and medicinal value,especially Cardamine,which has strong selenium-rich ability and is worthy of vigorous development.[Conclusions]This study provides scientific basis and reference for the development and utilization of local potherbs of Brassicaceae in this area. | Yaowen XU Shuiyuan CHENG Yongjun FEI Zurong CAO Yingjie LI Longsheng HU | 2021 | Agricultural Biotechnology2021，10，5： | 0 |
| 9 | Impact of Alkoxyl Tail of Fullerene Dyad Acceptor on Crystalline Microstructure for Efficient External Treatment-free Polymer Solar Cells with Poly(3-hexylthiophene) as Donor显示文摘 | XUE Rongming ZHAO Yue XU Guiying LI Yaowen LI Yongfang | 2015 | Chemical Research in Chinese Universities2015，31，5： | 0 |
| 10 | Effect of Nb on the Microstructure and Properties of Cold Rolled and Annealed Mo Microalloyed Bainitic Steel显示文摘Two kinds of low carbon bainitic steels,Nb-free Mo bearing and Nb + Mo addition steels,were cold rolled and annealed to investigate the effect of micro-alloying element Nb on the microstructure and properties of Mo microalloyed low carbon high strength bainitic steel. No precipitates were observed in Nb-free Mo bearing steel,whereas,two types of precipitates,i.e.,Nb( C,N) and composite( Nb,Mo)( C,N),were observed in the Nb + Mo microalloyed steel,resulting in precipitation strengthening. The strength of Mo bearing steel was improved by addition of Nb under the same annealing conditions. The grain size of Nb addition steel was almost the same as Nb-free steel. Unlike the obvious grain refinement and precipitation strengthening in hot rolling,the increase in yield strength of Nb addition steels in cold rolling and annealing mainly results from the precipitation strengthening,while the effect of grain refinement strengthening can be almost ignored. | Yi Zhang Guang Xu Li Wang Yaowen Xu Zhengliang Xue | 2016 | Journal of Harbin Institute of Technology(New Series)2016，23，4： | 0 |
| 11 | 全基因组关联研究发现中国人群前列腺癌两个新易感位点9q31.2和19q13.4显示文摘0前言在全球范围内,前列腺癌的发病率和病死率存在着巨大差异。该病在西方发达国家发病率最高,在非裔美国人群病死率最高,而在亚洲人群中发病率及病死率均为全球最低,提示不同人种在前列腺癌的遗传方面存在异质性。在欧美和日本人群中,全基因组关联研究(GWAS)技术已经被用于检测前列腺癌的遗传易感性位点,但至今尚无关于GWAS检测中国人群前列腺癌易感位点的报道。 | Jianfeng Xu Zengnan Mo Dingwei Ye Meilin Wang Fang Liu Guangfu Jin Chuanliang Xu Xiang Wang Qiang Shao Zhiwen Chen Zhihua Tao Jun Qi Fangjian Zhou Zhong Wang Yaowen Fu Dalin He Qiang Wei Jianming Guo Denglong Wu Xin Gao Jianlin Yuan Gongxian Wang Yong Xu Guozeng Wang Haijun Yao Pei Dong Yang Jiao Mo Shen Jin Yang Jun Ou-Yang Haowen Jiang Yao Zhu Shancheng Ren Zhengdong Zhang Changjun Yin Xu Gao Bo Dai Zhibin Hu Yajun Yang Qijun Wu Hongyan Chen Peng Peng Ying Zheng Xiaodong Zheng Yongbing Xiang Jirong Long Jian Gong Rong Na Xiaoling Lin Hongjie Yu Sha Tao Junjie Feng Jishan Sun Wennuan Liu Ann Hsing Jianyu Rao Qiang Ding Fredirik Wiklund Henrik Gronberg Xiao-Ou Shu Wei Zheng Hongbing Shen Li Jin Rong Shi Daru Lu Xuejun Zhang Jielin Sun S Lilly Zheng Yinghao Sun | 2013 | 第二军医大学学报2013，34，4： | 0 |
| 12 | Research on key technologies of edge cache in virtual data space across WAN显示文摘The authors of this paper have previously proposed the global virtual data space system (GVDS) to aggregate the scattered and autonomous storage resources in China’s national supercomputer grid (National Supercomputing Center in Guangzhou, National Supercomputing Center in Jinan, National Supercomputing Center in Changsha, Shanghai Supercomputing Center, and Computer Network Information Center in Chinese Academy of Sciences) into a storage system that spans the wide area network (WAN), which realizes the unified management of global storage resources in China. At present, the GVDS has been successfully deployed in the China National Grid environment. However, when accessing and sharing remote data in the WAN, the GVDS will cause redundant transmission of data and waste a lot of network bandwidth resources. In this paper, we propose an edge cache system as a supplementary system of the GVDS to improve the performance of upper-level applications accessing and sharing remote data. Specifically, we first designs the architecture of the edge cache system, and then study the key technologies of this architecture: the edge cache index mechanism based on double-layer hashing, the edge cache replacement strategy based on the GDSF algorithm, the request routing based on consistent hashing method, and the cluster member maintenance method based on the SWIM protocol. The experimental results show that the edge cache system has successfully implemented the relevant operation functions (read, write, deletion, modification, etc.) and is compatible with the POSIX interface in terms of function. Further, it can greatly reduce the amount of data transmission and increase the data access bandwidth when the accessed file is located at the edge cache system in terms of performance, i.e., its performance is close to the performance of the network file system in the local area network (LAN). | Jiantong HUO Yaowen XU Zhisheng HUO Limin XIAO Zhenxue HE | 2023 | Frontiers of Computer Science2023，17，1： | 0 |
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