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| 1 | Angular response of ‘pin-hole' imaging structure measured by collimated β source显示文摘The pitch-angle distribution of energetic particles is important for space physics studies on magnetic storm and particle acceleration.A‘pin-hole’imaging structure is built with the‘pin-hole’technique and a position sensitive detector,which can be used to measure the pitch angle distribution of energetic particles.To calibrate the angular response of the‘pin-hole’imaging structure,special experiment facilities are needed,such as the particle accelerator with special design.The features of this kind of particle accelerator are:1)The energy range of the outgoing particles should be mid-energy particles(tens keV to several hundred keV);2)the particle flux should be consistent in time-scale;3)the directions of the outgoing particles should be the same and 4)the particle number within the spot should be low enough.In this paper,a method to calibrate the angular response of the‘pin-hole’imaging structure by the90Sr/90Y β source with a collimator is introduced and simulated by Geant4 software.The result of the calibration with the collimated β source is in accord with the Geant4 simulations,which verifies the validity of this method. | ZOU Hong LUO Lin LI ChenFang JIA XiangHong XU Feng CHEN HongFei CHEN Jiang SHI WeiHong YU XiangQian ZOU JiQing | 2013 | Science China(Technological Sciences)2013，56，11： | 10 |
| 2 | Anatomical variation of infra-pyloric artery origination: A prospective multicenter observational study (IPA-Origin)显示文摘Objective: Infra-pyloric artery(IPA) is an important anatomical landmark in treatment of gastric cancer and is the key vessel for pylorus-preserving gastrectomy and subgroup of infra-pyloric lymph nodes. However, its anatomical variation is not thoroughly understood. Our study aimed to clarify the origination of the IPA.Methods: We did this prospective, multicenter, open-label, observational study at gastric surgery departments of34 hospitals in China. Gastric cancer patients aged 18 years or older and scheduled to undergo elective total or distal gastrectomy were assigned. During the surgery, IPA dissecting and exposing the origination point with photographs or video clips were required. The primary outcome was the origination of the IPA. Analysis of variance, χ~2 tests and Fisher's tests were used to analyze the differences between groups. The study is registered at Clinicaltrials.gov(No. NCT03071237).Results: Between May 8 and July 31, 2017, 429 patients were assigned for the study, and 419(97.7%) patients had the IPA dissected and recorded through photograph or video and were included in the primary outcome analysis. The median age was 62 years old, and 73.7% were male. Among the patients, 78.5% received laparoscopic surgery. Single IPA origination was identified in 398(95.0%) patients, including gastroduodenal artery(GDA) in154(36.8%) patients, anterior superior pancreaticoduodenal artery(ASPDA) in 130(31.0%) patients, and right gastroepiploic artery(RGEA) in 114(27.2%) patients. Fifteen(3.6%) patients were identified with multiple IPA and 6(1.4%) patients were identified as IPA absence. The differences in the distribution of surgical approach(P=0.003) and geographic area(P=0.030) were statistically significant. No difference was shown in sex, age,gastrectomy type, tumor location, and clinical T, N and M stage.Conclusions: Our study found that the IPA originates from GDA, ASPDA and RGEA in similar proportions.Laparoscopic surgery may be more helpful in dissection of the IPA than open surgery. | Rulin Miao Jianjun Qu Zhengrong Li Daguang Wang Jiang Yu Weidong Zang Yong Li Fenglin Liu Jian Zhang Wu Song Kai Ye Su Yan Wei Wang Shuangyi Ren Lu Zang Changqing Jing Li Zhang Kuan Wang Weihua Fu Lin Fan Bin Liang Gang Zhao Jun Cai Li Yang Jiaming Zhu Jun You Kun Yang Qingxing Huang Zhaojian Niu Ning Ning Xingfeng Qiu Gang Ji Feng Liang Hua Huang Chao Gao Fei Shan Shuangxi Li Yongning Jia Lianhai Zhang Xiangji Ying Yan Zhang Zhaode Bu Xiangqian Su Gang Zhao Ziyu Li Jiafu Ji | 2018 | Chinese Journal of Cancer Research2018，30，5： | 5 |
| 3 | Imaging energetic electron spectrometer onboard a Chinese navigation satellite in the inclined GEO orbit显示文摘The energetic electron measurement is one of the most important issues to understand dynamics in space physics and the applications for space weather. In this study, the principle and functional components of the imaging energetic electron spectrometer(IES) onboard a Chinese navigation satellite in the inclined GEO orbit(IGSO) was introduced. The IES instrument is developed by the team in Peking University(BeiDa), thus it is named as BD-IES. Based on the pin-hole technique, the instrument can measure 50–600 keV electrons incident from 9 directions over a range of 180° in polar angle. With pulse height analysis(PHA), the spectrum can be determined for each direction. The energy and angular calibrations were performed, which show the good energy and angular characteristics of BD-IES. Monte Carlo simulations show that the anti-proton design of BDIES can effectively decrease the proton contamination on the electron measurements in the inclined GEO orbit. The primary results of BD-IES verify the successful design of this instrument. | ZOU Hong YE YuGuang ZONG QiuGang CHEN HongFei ZOU JiQing CHEN Jiang SHI WeiHong YU XiangQian ZHONG WeiYing WANG YongFu ZHOU XuZhi HAO YiXin CHEN XingRan JIA XiangHong XU Feng SHAO SiPei WANG Bo HAO XiaoYun ZHANG XiaoXin | 2018 | Science China(Technological Sciences)2018，61，12： | 5 |
| 4 | Monte Carlo simulations of the sensor head of imaging energetic electron spectrometer onboard a Chinese IGSO navigation satellite显示文摘An imaging energetic electron spectrometer built by the Peking University team(BD-IES) onboard a Chinese navigation satellite in an inclined GEO orbit has been launched successfully in September 2015, which measures the spectra of the energetic electrons with the energy range of 50–600 keV in nine directions. In this study, Monte Carlo simulations of the BD-IES sensor head were performed using Geant4 and the corresponding characteristic responses to the isotropic energetic particles were derived. The effective geometric factors were estimated using the typical electron and proton spectra in the GEO orbit and the corresponding simulated sensor head responses. It was found that the average effective geometric factors of nine directions are close to the nominal geometric factors calculated with the traditional method, but the effective geometric factor decreases as the center energy of the energy channel decreases. The BD-IES sensor head also responses to the energetic protons, but the average contamination rate of all 72 channels is about 2%, which means that the proton contamination is acceptable. The spectra of the energetic electrons measured by BD-IES are derived using the effective geometric factors of the sensor head and are comparable with the spectra measured by the magnetic electron ion spectrometer(MagEIS) instrument onboard Van Allen Probes. | ZOU Hong YE YuGuang ZONG QiuGang CHEN HongFei LUO Lin ZHOU XuZhi CHEN XingRan HAO YiXin REN Jie WANG YongFu SHI WeiHong YU XiangQian JIA XiangHong XU Feng ZHANG XiaoXin | 2019 | Science China(Technological Sciences)2019，62，7： | 3 |
| 5 | Performance Analysis and Evaluation of Geometric Parameters in Stereo Deflectometry显示文摘This paper presents a novel geometric parameters analysis to improve the measurement accuracy of stereo deflectometry.Stereo deflectometry can be used to obtain form information for freeform specular surfaces.A measurement system based on stereo deflectometry typically consists of a fringe-displaying screen,a main camera,and a reference camera.The arrangement of the components of a stereo deflectometry system is important for achieving high-accuracy measurements.In this paper,four geometric parameters of a stereo deflectometry system are analyzed and evaluated:the distance between the main camera and the measured object surface,the angle between the main camera ray and the surface normal,the distance between the fringe-displaying screen and the object,and the angle between the main camera and the reference camera.The influence of the geometric parameters on the measurement accuracy is evaluated.Experiments are performed using simulated and experimental data.The experimental results confirm the impact of these parameters on the measurement accuracy.A measurement system based on the proposed analysis has been set up to measure a stock concave mirror.Through a comparison of the given surface parameters of the concave mirror,a global measurement accuracy of 154.2 nm was achieved. | Yongjia Xu Feng Gao Xiangqian Jiang | 2018 | Engineering2018，4，6： | 3 |
| 6 | Improved shape memory composites combined with TiNi wire and shape memory epoxy显示文摘 | Xue Feng Limin Zhao Xujun Mi Yanfeng Li Haofeng Xie Xiangqian Yin Baodong Gao | 2013 | Materials and Design2013，，： | 1 |
| 7 | Study of buffer and epitaxy technology in two-step growth of aluminium nitride显示文摘AlN (aluminium nitride) films were prepared by metalorganic chemical vapor depo- sition (MOCVD) on c-plane sapphire (α-Al2O3) substrates. By means of studying the traces of in-situ optical reflectivity, it was found that the AlN nucleation layer showed a specific (0001) lattice orientation, which differed from the GaN nucleation layer on (0001) sapphire substrates. The AlN buffer suffered the compressive stress at the initial stage of nucleation. And the compressive strain was relaxed gradually along with the thickness of buffer increasing and consequently annealing. Optical transmission spectra revealed that in the process of growing AlN epilayers, higher V/III ratio could improve the crystal quality but reduce the growth rates. In addition, proper doping of silane (SiH4) could improve the surface morphology of AlN film. | LIU QiJia ZHANG Rong XIE ZiLi LIU Bin XU Feng YAO Jing NIE Chao XIU XiangQian HAN Ping ZHENG YouDou GONG HaiMei | 2008 | Science China(Technological Sciences)2008，51，11： | 1 |
| 8 | Fibronectin and asialoglyprotein receptor mediate hepatitis B surface antigen binding to the cell surface显示文摘 | Jing Yang Feng Wang Linlin Tian Jing Su Xiangqian Zhu Li Lin Xiaoran Ding Xuejun Wang Shengqi Wang | 2010 | Archives of Virology2010，，6： | 1 |
| 9 | Intelligent techniques for cigarette formula design显示文摘 | Tianjin Feng Lintao Ma Xiangqian Ding | 2008 | Mathematics and Computers in Simulation2008，，77： | 1 |
| 10 | 3-Thiomorpholin-8-oxo-8 H -acenaphtho [1,2- b ] pyrrole-9-carbonitrile ( S1 ) derivatives as pan-Bcl-2-inhibitors of Bcl-2, Bcl-x L and Mcl-1显示文摘 | Ting Song Xiangqian Li Xilong Chang Xiaomeng Liang Yan Zhao Guiye Wu Shenghui Xie Pengchen Su Zhiyong Wu Yingang Feng Zhichao Zhang | 2013 | Bioorganic & Medicinal Chemistry2013，，1： | 1 |
| 11 | A hybrid CNN-LSTM model for diagnosing rice nutrient levels at the rice panicle initiation stage显示文摘Nitrogen(N)and potassium(K)are two key mineral nutrient elements involved in rice growth.Accurate diagnosis of N and K status is very important for the rational application of fertilizers at a specific rice growth stage.Therefore,we propose a hybrid model for diagnosing rice nutrient levels at the early panicle initiation stage(EPIS),which combines a convolutional neural network(CNN)with an attention mechanism and a long short-term memory network(LSTM).The model was validated on a large set of sequential images collected by an unmanned aerial vehicle(UAV)from rice canopies at different growth stages during a two-year experiment.Compared with VGG16,AlexNet,GoogleNet,DenseNet,and inceptionV3,ResNet101 combined with LSTM obtained the highest average accuracy of 83.81%on the dataset of Huanghuazhan(HHZ,an indica cultivar).When tested on the datasets of HHZ and Xiushui 134(XS134,a japonica rice variety)in 2021,the ResNet101-LSTM model enhanced with the squeeze-and-excitation(SE)block achieved the highest accuracies of 85.38 and 88.38%,respectively.Through the cross-dataset method,the average accuracies on the HHZ and XS134 datasets tested in 2022 were 81.25 and 82.50%,respectively,showing a good generalization.Our proposed model works with the dynamic information of different rice growth stages and can efficiently diagnose different rice nutrient status levels at EPIS,which are helpful for making practical decisions regarding rational fertilization treatments at the panicle initiation stage. | Fubing Liao Xiangqian Feng Ziqiu Li Danying Wang Chunmei Xu Guang Chu Hengyu Ma Qing Yao Song Chen | 2024 | Journal of Integrative Agriculture2024，23，2： | 0 |
| 12 | Improved diagnosis of thyroid cancer aided with deep learning applied to sonographic text reports:a retrospective,multi-cohort,diagnostic study显示文摘Objective:Large volume radiological text data have been accumulated since the incorporation of electronic health record(EHR)systems in clinical practice.We aimed to determine whether deep natural language processing algorithms could aid radiologists in improving thyroid cancer diagnosis.Methods:Sonographic EHR data were obtained from the EHR database.Pathological reports were used as the gold standard for diagnosing thyroid cancer.We developed thyroid cancer diagnosis based on natural language processing(THCaDxNLP)to interpret unstructured sonographic text reports for thyroid cancer diagnosis.We used the area under the receiver operating characteristic curve(AUROC)as the primary metric to measure the performance of the THCaDxNLP.We compared the performance of thyroid ultrasound radiologists aided with THCaDxNLP vs.those without THCaDxNLP using 5 independent test sets.Results:We obtained a total number of 788,129 sonographic radiological reports.The number of thyroid sonographic data points was 132,277,18,400 of which were thyroid cancer patients.Among the 5 test sets,the numbers of patients per set were 439,186,82,343,and 171.THCaDxNLP achieved high performance in identifying thyroid cancer patients(the AUROC ranged from 0.857–0.932).Thyroid ultrasound radiologists aided with THCaDxNLP achieved significantly higher performances than those without THCaDxNLP in terms of accuracy(93.8%vs.87.2%;one-sided t-test,adjusted P=0.003),precision(92.5%vs.86.0%;P=0.018),and F1 metric(94.2%vs.86.4%;P=0.007).Conclusions:THCaDxNLP achieved a high AUROC for the identification of thyroid cancer,and improved the accuracy,sensitivity,and precision of thyroid ultrasound radiologists.This warrants further investigation of THCaDxNLP in prospective clinical trials. | Qiang Zhang Sheng Zhang Jianxin Li Yi Pan Jing Zhao Yixing Feng Yanhui Zhao Xiaoqing Wang Zhiming Zheng Xiangming Yang Lixia Liu Chunxin Qin Ke Zhao Xiaonan Liu Caixia Li Liuyang Zhang Chunrui Yang Na Zhuo Hong Zhang Jie Liu Jinglei Gao Xiaoling Di Fanbo Meng Wei Ji Meng Yang Xiaojie Xin Xi Wei Rui Jin Lun Zhang Xudong Wang Fengju Song Xiangqian Zheng Ming Gao Kexin Chen Xiangchun Li | 2022 | Cancer Biology & Medicine2022，19，5： | 0 |
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