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| 1 | Prospects and research issues in multi-dimensional all optical networks显示文摘Research into all optical network(AON) technology has been ongoing over the past decade, and new features are constantly being developed. The advantages of AON include large-bandwidth provisioning, lowlatency transmission and low energy consumption. The basic concept underlying AON is transmission of data signals entirely through the optical domain from source to destination nodes, with no optical-electrical-optical(O-E-O) conversion at intermediate nodes. The technologies used to implement AON have undergone a series of evolutions, which encompass time division multiplexing(TDM), frequency division multiplexing(FDM), and space division multiplexing(SDM). Multi-dimensional AON(MD-AON), which leads the trend of AON's future architecture, provides a vibrant state for emerging applications such as cloud computing and Internet of Things(Io T). In this article, we review the evolution of AON architectures based on the different all optical switching and multiplexing technologies(i.e., TDM, FDM, and SDM), which is one of the main areas of focus in this article.The other main area is detailed discussion of implementations such as data plane and control plane technologies as well as resource optimization technologies for realizing AON. We also introduce several AON testbeds with their compositions and functions, and some potential application scenarios that can be implemented based on these | Yuefeng JI Jiawei ZHANG Yongli ZHAO Xiaosong YU Jie ZHANG Xue CHEN | 2016 | Science China(Information Sciences)2016，59，10： | 3 |
| 2 | Adult rat bone marrow stromal cells differentiate into Schwann cell-like cells in vitro显示文摘 | WeiWei Lin Xue Chen XiaoDong Wang Jie Liu XiaoSong Gu | 2008 | In Vitro Cellular & Developmental Biology - Animal (-)2008，，1： | 1 |
| 3 | Isolating Host Environment by Booting Android from OTG Devices显示文摘With the integration of smartphone into daily life, end users store a large amount of sensitive information into Android device. For protecting the sensitive information, a method of multi-booting Android OS from On-The-Go(OTG) device is proposed to meet the requirements of end users in different scenarios. The proposed method utilizes system domain isolation to guarantee the security of sensitive information on different Android OS.The difference with other solutions is that our proposed solution does not add additional components to Android OS,which makes the overhead of Android runtime has been effectively controlled. A prototype of the proposed method is implemented and deployed into the real android device to evaluate the effectiveness, the efficiency and the performance overhead. The experiment results show that the performance overhead is reasonable and our method can effectively mitigate the risk of sensitive information leakage when booting different Android instance in the same Android device. | XUE Yuan ZHANG Xiaosong YU Xiao ZHANG Yaoyuan TAN Yu'an LI Yuanzhang | 2018 | Chinese Journal of Electronics2018，27，3： | 1 |
| 4 | Developmental Temporal Patterns and Molecular Network Features in the Transcriptome of Rat Spinal Cord显示文摘The molecular network features of spinal cord development that are integral to tissue engineering remain poorly understood in placental mammals,especially in terms of their relationships with vital biological processes such as regeneration.Here,using a large-scale temporal transcriptomic analysis of rat spinal cord from the embryonic stage to adulthood,we show that fluctuating RNA expression levels reflect highly active transcriptional regulation,which may initiate spinal cord patterning.We also demonstrate that microRNAs(miRNAs)and transcriptional factors exhibit a mosaic profile based on their expression patterns,while differential alternative splicing events reveal that alternative splicing may be a driving force for the development of the node of Ranvier.Our study also supports the existence of a negative correlation between innate immunity and intrinsic growth capacity.Epigenetic modifications appear to perform their respective regulatory functions at different stages of development,while guanine nucleotidebinding protein(G protein)-coupled receptors(including olfactory receptors(ORs))may perform pleiotropic roles in axonal growth.This study provides a valuable resource for investigating spinal cord development and complements the increasing number of single-cell datasets.These findings also provide a genetic basis for the development of novel tissue engineering strategies. | Jian Yang Lili Zhao Sheng Yi Fei Ding Yumin Yang Yan Liu Yongjun Wang Mei Liu Chengbin Xue Lian Xu Leilei Gong Xinghui Wang Yu Zhang Bin Yu Guo-li Ming Xiaosong Gu | 2021 | Engineering2021，7，11： | 0 |
| 5 | Synthesis and Antitumor Activity Evaluation of Pyrimidine Analogues Bearing Urea Moiety显示文摘A series of 4-anilino-6-phenylpyrimidines containing urea moiety were synthesized and the structures of all products were confirmed by^(1)H NMR,^(13)C NMR and HRMS.The antiproliferative activities of these compounds were evaluated against three human tumor cell lines(MGC-803,MCF-7 and EC-109)by applying the MTT assay method.compounds 4a,4b and 6a showed the most effective activity,among which,6a was more cytotoxic than 5-fluorouracil against all tested human cancer cell lines with IC_(50) values ranging from 1.80 to 2.72μmol·L^(-1). | Kunpeng Shao Xuyao Zhang Xiaosong Zhang Dengqi Xue Liying Ma Qiurong Zhang Hongmin Liu | 2014 | Chinese Journal of Chemistry2014，32，5： | 0 |
| 6 | Prevalence of Reproductive Tract Infections and Association with Human Papillomavirus Infection Among Reproductive-Age Women—Six Tertiary Hospitals,China,June 2021-December 2022显示文摘Summary What is already known about this topic?Previous studies have indicated a possible association between reproductive tract infections(RTIs)and highrisk human papillomavirus(HPV)infection,but the evidence is still inconclusive.What is added by this report?This multicenter study found significantly higher positive rates of HPV,including general HPV,highrisk HPV. | Di Gao Jiayue Li Gengli Zhao Zhaohui Liu Hui Bi Dai Zhang Fengxia Xue Chen Liu Hongtao Ma Bei Lin Xu Wang Xiaosong Zhang Linhong Wang | 2024 | China CDC weekly2024，6，10： | 0 |
| 7 | Systematic evaluation of IgG responses to SARS-CoV-2 spike protein-derived peptides for monitoring COVID-19 patients显示文摘Serological tests play an essential role in monitoring and combating the COVID-19 pandemic.Recombinant spike protein(S protein),especially the S1 protein,is one of the major reagents used for serological tests.However,the high cost of S protein production and possible cross-reactivity with other human coronaviruses pose unavoidable challenges.By taking advantage of a peptide microarray with full spike protein coverage,we analyzed 2,434 sera from 858 COVID-19 patients,63 asymptomatic patients and 610 controls collected from multiple clinical centers.Based on the results,we identified several S protein-derived 12-mer peptides that have high diagnostic performance.In particular,for monitoring the IgG response,one peptide(aa 1148-1159 or S2-78)exhibited a sensitivity(95.5%,95%CI 93.7-96.9%)and specificity(96.7%,95%CI 94.8-98.0%)comparable to those of the S1 protein for the detection of both symptomatic and asymptomatic COVID-19 cases.Furthermore,the diagnostic performance of the S2-78(aa 1148-1159)IgG was successfully validated by ELISA in an independent sample cohort.A panel of four peptides,S1-93(aa 553-564),S1-97(aa 577-588),S1-101(aa 601-612)and S1-105(aa 625-636),that likely will avoid potential cross-reactivity with sera from patients infected by other coronaviruses was constructed.The peptides identified in this study may be applied independently or in combination with the S1 protein for accurate,affordable,and accessible COVID-19 diagnosis. | Yang Li Dan-yun La Qing Lei Zhao-wei Xu Feng Wang Hongyan Hou Lingyun Chen Jiaoxiang Wu Yan Ren Ming-liang Ma Bo Zhang Hong Chen Caizheng Yu Jun-biao Xue Yun-xiao Zheng Xue-ning Wang He-wei Jiang Hai-nan Zhang Huan Qi Shu-juan Guo Yandi Zhang Xiaosong Lin Zongjie Yao Pengfei Pang Dawei Shi Wei Wang Xiao Yang Jie Zhou Huiming Sheng Ziyong Sun Hong Shan Xionglin Fan Sheng-ce Tao | 2021 | Cellular & Molecular Immunology2021，18，3： | 0 |
| 8 | Photonic-reconfigurable entanglement distribution network based on silicon quantum photonics显示文摘The entanglement distribution network connects remote users by sharing entanglement resources,which is essential for realizing quantum internet.We propose a photonic-reconfigurable entanglement distribution network(PR-EDN)based on a silicon quantum photonic chip.The entanglement resources are generated by a quantum light source array based on spontaneous four-wave mixing in silicon waveguides and distributed to different users through time-reversed Hong–Ou–Mandel interference by on-chip Mach–Zehnder interferometers with thermo-optic phase shifters(TOPSs).A chip sample is designed and fabricated,supporting a PR-EDN with3 subnets and 24 users.The network topology of the PR-EDN could be reconfigured in three network states by controlling the quantum interference through the TOPSs,which is demonstrated experimentally.Furthermore,a reconfigurable entanglement-based quantum key distribution network is realized as an application of the PR-EDN.The reconfigurable network topology makes the PR-EDN suitable for future quantum networks requiring complicated network control and management.Moreover,it is also shown that silicon quantum photonic chips have great potential for large-scale PR-EDN,thanks to their capacities for generating and manipulating plenty of entanglement resources. | DONGNING LIU JINGYUAN LIU XIAOSONG REN XUE FENG FANG LIU KAIYU CUI YIDONG HUANG WEI ZHANG | 2023 | Photonics Research2023，11，7： | 0 |
| 9 | COVID-ONE-hi:The One-stop Database for COVID-19-specific Humoral Immunity and Clinical Parameters显示文摘Coronavirus disease 2019(COVID-19),which is caused by SARS-CoV-2,varies with regard to symptoms and mortality rates among populations.Humoral immunity plays critical roles in SARS-CoV-2 infection and recovery from COVID-19.However,differences in immune responses and clinical features among COVID-19 patients remain largely unknown.Here,we report a database for COVID-19-specific IgG/IgM immune responses and clinical parameters(named COVID-ONE-hi).COVID-ONE-hi is based on the data that contain the IgG/IgM responses to 24 full-length/truncated proteins corresponding to 20 of 28 known SARS-CoV-2 proteins and 199 spike protein peptides against 2360 serum samples collected from 783 COVID-19 patients.In addition,96 clinical parameters for the 2360 serum samples and basic information for the 783 patients are integrated into the database.Furthermore,COVID-ONE-hi provides a dashboard for defining samples and a one-click analysis pipeline for a single group or paired groups.A set of samples of interest is easily defined by adjusting the scale bars of a variety of parameters.After the“START”button is clicked,one can readily obtain a comprehensive analysis report for further interpretation.COVID-ONE-hi is freely available at www.COVID-ONE.cn. | Zhaowei Xu Yang Li Qing Lei Likun Huang Dan-yun Lai Shu-juan Guo He-wei Jiang Hongyan Hou Yun-xiao Zheng Xue-ning Wang Jiaoxiang Wu Ming-liang Ma Bo Zhang Hong Chen Caizheng Yu Jun-biao Xue Hai-nan Zhang Huan Qi Siqi Yu Mingxi Lin Yandi Zhang Xiaosong Lin Zongjie Yao Huiming Sheng Ziyong Sun Feng Wang Xionglin Fan Sheng-ce Tao | 2021 | Genomics, Proteomics & Bioinformatics2021，19，5： | 0 |
| 10 | Neutral Five-Coordinate Arylated Copper(Ⅲ) Complex: Key Intermediate in Copper-Mediated Arene Trifluoromethylation显示文摘Five-coordinate neutral Cu(Ⅲ)complexes have long been considered as the key intermediates in copper-mediated/catalyzed arene trifluoromethylative reactions,but the identity of these complexes remains elusive.Herein,we reported,for the first time,the preparation and characterization of these putative complexes[(bpy)Cu(CF_(3))_(2)(C_(6)F_(4)R)]and investigation of their C(sp^(2))-CF_(3) bond-forming reductive elimination.Our mechanistic studies including kinetic studies,the effect of temperature and solvents,the effect of the para-substitution of the ligand as well as DFT calculations suggest that C(sp^(2))-CF_(3) reductive elimination process proceeds via synchronous bond-breaking/bond-forming process. | Guangyu Wang Man Li Xuebing Leng Xiaosong Xue Qilong Shen | 2022 | Chinese Journal of Chemistry2022，40，16： | 0 |
| 11 | Role of the rhizosphere of a flooding-tolerant herb in promoting mercury methylation in water-level fluctuation zones显示文摘The water-level fluctuation zone(WLFZ) has been considered as a hotspot for mercury(Hg) methylation. Flooding-tolerant herbs are gradually acclimated to this water-land ecotone, tending to form substantial root systems for improving erosion resistance. Accompanying rhizosphere microzone plays crucial but unclear roles in methylmercury(Me Hg) formation in the WLFZ. Thus, we conducted this study in the WLFZ of the Three Gorges Reservoir, to explore effects of the rhizosphere of a dominant flooding-tolerant herb(bermudagrass) on Me Hg production. The elevated Hg and Me Hg in rhizosphere soils suggest that the rhizosphere environment provides favorable conditions for Hg accumulation and methylation. The increased bioavailable Hg and microbial activity in the rhizosphere probably serve as important factors driving Me Hg formation in the presence of bermudagrass. Simultaneously, the rhizosphere environments changed the richness, diversity, and distribution of hgc A-containing microorganisms. Here, a typical ironreducing bacterium( Geobacteraceae) has been screened, however, the majority of hgc A genes detected in rhizosphere, near-, and non-rhizosphere soils of the WLFZ were unclassified. Collectively, these results provide new insights into the elevated Me Hg production as related to microbial processes in the rhizosphere of perennial herbs in the WLFZ, with general implications for Hg cycling in other ecosystems with water-level fluctuations. | Juan Wang Yuping Xiang Xiaosong Tian Cheng Zhang Guiqing Gong Jinping Xue Tao Jiang Dingyong Wang Yongmin Wang | 2022 | Journal of Environmental Sciences2022，34，9： | 0 |
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