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| 1 | Soil Microbial Population Dynamics along a Chronosequence of Moist Evergreen Broad-leaved Forest Succession in Southwestern China显示文摘Little is known about whether soil microbial population dynamics are correlated with forest succession.To test the hypotheses that(1) soil microbial composition changes over successional stages,and(2) soil microbial diversity is positively correlated with plant species diversity,we determined the soil microbial populations,community composition,and microflora diversity in evergreen broad-leaved forests along a chronosequence of vegetation succession from 5 to 300 years in southwestern China.The soil microbial community was mainly composed of bacteria(87.1-98.7% of the total microorganisms and 10 genera identified),fungi(0.3-4.0%,7 genera),and actinomycetes(2.1-9.1%,8 species and 1 genus).There were significant differences in soil microbial populations among different successional stages and within the four seasons.The seasonal variations of the soil microbial community may be associated with the seasonal changes in environmental conditions.The changes in soil microbial diversity(Shannon-Wiener index) with successional time followed one-humped,convex curves peaked at-100 years since restoration,which is identical with the trends of the aboveground plant diversity.Higher plant diversity resulting in enhanced nutrient flow and root exudation may contribute to positive relationships between the soil microbial diversity and plant diversity.Hence,decreases in soil microbial diversity in the late-successional stages appear to be related to the net loss in species richness that occurs after 100 years since restoration.Our findings confirm the intermediate disturbance hypothesis that suggests diversity peaks at midsuccessional stages. | ZHU Wanze CAI Xiaohu LIU Xingliang WANG Jinxi CHENG Song ZHANG Xiuyan LI Dengyu LI Maihe | 2010 | Journal of Mountain Science2010，7，4： | 8 |
| 2 | Anomalous Phase Transformation from Martensite to Austenite in Fe-13%Cr-4%Ni-Mo Martensitic Stainless Steel显示文摘The thermal stability of the reversed austenite in a low carbon Fe-13%Cr-4%Ni-Mo(in wt pct) martensitic stainless steel was investigated by X-ray diffraction(XRD) and superconducting quantum interference device(SQUID) magnetometer.Different amount of the reversed austenite was obtained by controlling tempered temperature.It was found that the amount of the reversed austenite increased after keeping the specimens at liquid nitrogen temperature for 72 h.The mechanism of the anomalous phase transformation from martensite to austenite was discussed. | Yuanyuan Song,Xiuyan Li,Lijian Rong and Yiyi Li Institute of Metal Research,Chinese Academy of Sciences,Shenyang 110016,China | 2010 | Journal of Materials Science & Technology2010，26，9： | 4 |
| 3 | TCMSTD 1.0: a systematic analysis of the traditional Chinese medicine system toxicology database显示文摘Dear Editor,The safety and modernization of traditional Chinese medicine (TCM) are significant concerns for users’ lives and health. Recently, the adverse effects caused by TCM and traditional nontoxic TCM have been frequently reported (Joo et al., 2020;Liu et al., 2021). As the safety of TCM continues to attract widespread attention, many researchers have been investigating the toxicity of TCM in regard to the toxic ingredients, effects, mechanisms, and detoxification strategies in TCM (Figure S1 in Supporting Information). Although some TCMs cause toxic reactions, they also play key roles in treating certain unignorable diseases (Fang et al., 2022).Therefore, toxicity research is crucial and urgently needed to develop and safely use TCM. | Lili Song Wenxiu Qian Hongqing Yin Yu Sun Xiuyan Sun Guohui Li Junjie He Yanxue Zheng Yue Zhang Jiayi Wang Yubo Li | 2023 | Science China(Life Sciences)2023，66，9： | 3 |
| 4 | The influence of tempering temperature on the reversed austenite formation and tensile properties in Fe-13% Cr-4% Ni-Mo low carbon martensite stainless steels 显示文摘 | Song Yuanyuan Li Xiuyan Rong Lijian | 2011 | Materials Science and Engineering: A2011，528，12： | 1 |
| 5 | Hydrolysis of poly carbonate catalyzed by ionic liquid 显示文摘 | Xiuyan Song Fusheng Liu Lei Li | 2013 | Journal of Hazardous Materials2013，，： | 1 |
| 6 | Methanolysis of poly(lactlc acid) catalyzed by ionic liquid显示文摘 | Xiuyan Song Xiaojing Zhang Hui Wang | 2013 | Polymer Degradation and Stability2013，98，12： | 1 |
| 7 | Oxidative dual C-H sulfenylation:A strategy for the synthesis of bis(imidazo[1,2-a]pyridin-3-yl)sulfanes under metal-free conditions using sulfur powder显示文摘An efficient approach to sulfur-bridged imidazopyridines has been developed under metal-free conditions using inexpensive sulfur powder as the sulfur source.Most appealingly,the reaction can proceed smoothly without addition of any additives,ultimately decreasing the production of chemical waste.The inexpensive and green method should provide a useful strategy for constructing a library of novel and biological interesting heteroaromatic sulfides. | Ziyu Gan Xiaolong Zhu Qiuli Yan Xiuyan Song Daoshan Yang | 2021 | Chinese Chemical Letters2021，32，5： | 1 |
| 8 | Hydrolysis of polycarbonate catalyzed by ionic liquid [Bmim][Ac]显示文摘 | Xiuyan Song Fusheng Liu Lei Li Xuequn Yang Shitao Yu Xiaoping Ge | 2013 | Journal of Hazardous Materials2013，，： | 1 |
| 9 | An electron donor-acceptor photoactivation strategy for the synthesis of S-aryl dithiocarbamates using thianthrenium salts under mild aqueous micellar conditions显示文摘An eco-friendly and convenient method is developed herein for the synthesis of S-aryl dithiocarbamates via visible-light-induced SET process of an EDA complex between thianthrenium salt functionalized arenes and dithiocarbamate anions under mild aqueous micellar conditions.This strategy indirectly realizes the method for constructing S-aryl dithiocarbamates through site-selective C−H functionalization of arenes.Most importantly,the reaction proceeded smoothly without addition of any photocatalyst,and the by-product thianthrene is recycled in quantity,ultimately minimizing the production of chemical waste.This protocol provides a promising synthesis candidate for the construction of valuable S-aryl dithiocarbamates,which also opens up a new avenue for micellar photocatalysis. | Hao Xu Xufeng Li Jie Ma Junze Zuo Xiuyan Song Jian Lv Daoshan Yang | 2023 | Chinese Chemical Letters2023，34，11： | 0 |
| 10 | Anti-Markovnikov ring-opening of sulfonium salts with alkynes by visible light/copper catalysis显示文摘Internal alkynes are widespread skeletons in bioactive molecules and materials which are also used as important building blocks in chemical synthesis. Herein, we report a novel and efficient copper-catalyzed Sonogashira reaction between sulfonium salts and alkynes through an anti-Markovnikov ring-opening pathway promoted by visible light. The coexistence of the nitrogen and phosphorus ligands in the system is the key to the success of this reaction. This radical type ring-opening reaction affords a new strategy for the synthesis of internal alkynes. Furthermore, this study is also an effective complement to the diverse reaction patterns of sulfonium salts. | Xuan Li Min Jiang Junze Zuo Xiuyan Song Jian Lv Daoshan Yang | 2023 | Science China Chemistry2023，66，3： | 0 |
| 11 | Ceritinib: From Synthesis to Clinical Applications显示文摘 | Xiuyan Cui Weihua Song Qi Yang Zhangqun Yang | 2016 | Journal of Pharmacy and Pharmacology2016，4，8： | 0 |
| 12 | Alkylsulfonium salts for the photochemical desulphurizative functionalization of heteroarenes显示文摘The development of new versatile alkylation reagents that can be transformed from diverse available chemical raw materials is highly desirable.Here,an efficient,metal-free organic photoredox-catalyzed direct alkylation of heteroarenes via a desulphurization strategy using alkylsulfonium salts as alkylation reagents under mild conditions has been described for the first time.The inexpensive and efficient organic photoredox-catalyzed method offers a new and useful strategy for constructing various biologically interesting heteroarenes in the fields of synthetic and pharmaceutical chemistry,and extends the scope of the still limited sulfonium salt photochemistry. | Xiaolong Zhu Min Jiang Xuan Li Enjie Zhu Qirong Deng Xiuyan Song Jian Lv Daoshan Yang | 2022 | Organic Chemistry Frontiers2022，9，2： | 0 |
| 13 | A desulphurization strategy for Sonogashira couplings by visible light/copper catalysis显示文摘The development of new copper-based catalysts in photoredox transformations has become a rapidly growing area of research and has been actively explored in the past several years.Herein,we have developed a new copper-based catalyst,[(binap)(tpy)Cu]Cl,and applied it in the visible-light promoted Sonogashira coupling reactions.This mild protocol results in various substituted alkynes from simple sulfonium salts which can be easily prepared from commercially available and inexpensive thiols,alcohols,and alkyl halides.This study will broaden the still limited strategies of copper photocatalysts in organic transformations. | Xuan Li Min Jiang Xiaolong Zhu Xiuyan Song Qirong Deng Jian Lv Daoshan Yang | 2022 | Organic Chemistry Frontiers2022，9，2： | 0 |
| 14 | Clinical Internship Teaching Management During the COVID-19 Epidemic显示文摘Against the backdrop of the global COVID-19 pandemic,the teaching and management of clinical medical interns have been facing tremendous challenges.When interns majoring in clinical medicine enter the internship position,they lack self-protection awareness and have limited ability to respond to unexpected public health events.This article explores the cognitive situation,existing problems,and improvement measures of clinical medical interns in the post-epidemic era.Therefore,this article proposes a series of improvement measures,including strengthening epidemic training and education for interns,enhancing personal protective awareness,and lastly achieving the role transition from intern to doctor. | Hai Zeng Binbin Song Qingbo Qiao Xue Zhao Rui Ma Dan Zhao Xiuyan Wang | 2023 | Journal of Contemporary Educational Research2023，7，10： | 0 |
| 15 | Targeting a cryptic allosteric site of SIRT6 with small-molecule inhibitors that inhibit the migration of pancreatic cancer cells显示文摘SIRT6 belongs to the conserved NAD^(+)-dependent deacetylase superfamily and mediates multiple biological and pathological processes.Targeting SIRT6 by allosteric modulators represents a novel direction for therapeutics,which can overcome the selectivity problem caused by the structural similarity of orthosteric sites among deacetylases.Here,developing a reversed allosteric strategy Allo Reverse,we identified a cryptic allosteric site,Pocket Z,which was only induced by the bi-directional allosteric signal triggered upon orthosteric binding of NAD^(+).Based on Pocket Z,we discovered an SIRT6 allosteric inhibitor named JYQ-42.JYQ-42 selectively targets SIRT6 among other histone deacetylases and effectively inhibits SIRT6 deacetylation,with an IC50 of 2.33μmol/L.JYQ-42 significantly suppresses SIRT6-mediated cancer cell migration and pro-inflammatory cytokine production.JYQ-42,to our knowledge,is the most potent and selective allosteric SIRT6 inhibitor.This study provides a novel strategy for allosteric drug design and will help in the challenging development of therapeutic agents that can selectively bind SIRT6. | Qiufen Zhang Yingyi Chen Duan Ni Zhimin Huang Jiacheng Wei Li Feng Jun-Cheng Su Yingqing Wei Shaobo Ning Xiuyan Yang Mingzhu Zhao Yuran Qiu Kun Song Zhengtian Yu Jianrong Xu Xinyi Li Houwen Lin Shaoyong Lu Jian Zhang | 2022 | Acta Pharmaceutica Sinica B2022，12，2： | 0 |
| 16 | Rapid formation of Csp^(3)–Csp^(3) bonds through copper-catalyzed decarboxylative Csp^(3)–H functionalization显示文摘Transition-metal-catalyzed decarboxylative and C–H functionalization strategy for the construction of Csp^(2)-Csp^(2),Csp^(2)-Csp,and Csp^(2)-Csp^(3) bonds has been extensively studied.However,research surveys of this synthetic strategy for the Csp^(3)-Csp^(3) bond forming reactions are surprisingly scarce.Herein,we present an efficient approach for the rapid formation of Csp^(3)–Csp^(3) bond through copper-catalyzed decarboxylative Csp^(3)–H functionalization.The present method should provide a useful access to C3-substituted indole scaffolds with possible biological activities.Mechanistic experiments and DFT calculations supported a dual-Cu(Ⅱ)-catalytic cycle involving rate-determining decarboxylation in an outer-sphere radical pathway and spin-crossover-promoted C–C bond formation.This strategy offers a promising synthesis method for the construction of Csp^(3)–Csp^(3) bond in the field of synthetic and pharmaceutical chemistry and extends the number of still limited copper-catalyzed decarboxylative Csp^(3)–Csp^(3) bond forming reaction. | Wenwen Cui Yu Li Xufeng Li Junxin Li Xiuyan Song Jian Lv Yuan-Ye Jiang Daoshan Yang | 2023 | Chinese Chemical Letters2023，34，1： | 0 |
| 17 | Synthetic optical vortex beams from the analogous trajectory change of an artificial satellite显示文摘We propose a method to generate specially shaped high-order singular beams of pre-designed intensity distributions. Such a method does not a priori assume a phase formula, but rather relies on the 'cake-cutting and assembly' approach to achieve the azimuthal phase gradient for beam shaping, inspired by the orbital motion trajectory change of an artificial satellite. Based on our method, several typical vortex beams with desired intensity patterns are experimentally generated. As an example, we realize optical trapping and transportation of microorganisms with a triangle-shaped vortex beam, demonstrating the applicability of such unconventional vortex beams in optical trapping and manipulation. | HAIPING WANG LIQIN TANG JINA MA XIUYAN ZHENG DAOHONG SONG YI HU YIGANG LI ZHIGANG CHEN | 2019 | Photonics Research2019，7，9： | 0 |
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