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| 1 | In vitro derivation of functional insulin-producing cells from human embryonic stem cells显示文摘为人的胚胎的茎(ES ) 的自强和区别的能力细胞为对待类型 Idiabetes mellitus 为胰腺的贝它细胞的产生使他们成为潜在的来源。这里,我们报导一最新发展了并且有效方法,在aserum免费的系统执行了,区分进生产胰岛素的 cells.Activin A 的导致的人的 ES 房间它在起始的阶段被使用从人的 EScells 导致权威的内胚叶区别,是由权威的内胚叶标记 Sox17 和 Brachyury.Further 的表示检测了, all-trans retinoic 酸( RA )被用来支持胰腺的区别,由早胰腺的抄写因素 pdx1 和 hlxb9 的表示显示了。在成熟 inDMEM/F12 以后有 bFGF 和菸碱的没有浆液的媒介,区分的房间表示了小岛特定的标记象 C 肽,胰岛素,胰高血糖素和 glut2 那样。百分比 ofC-peptide-positive 房间超过了 15% 。由这些房间的胰岛素和 C 肽的分泌物在葡萄糖层次对应于变化。当移植了进肾的囊时, ofStreptozotocin (STZ ) 对待裸体老鼠,这些区分的人的 ES 房间熬过并且维持贝它房间标记基因的表示包括 C 肽, pdx1, glucokinase, nkx6.1, IAPP, pax6and Tcf1。百分之三十只移植裸体老鼠展出了 stableeuglycemia 的明显的恢复;并且改正的显型被支撑超过六个星期。我们的新方法为学习人的胰开发的机制提供一个有希望的试管内区别模特儿并且说明为类型 Idiabetes mellitus 的处理使用人的 ES 房间的潜力。 | Wei Jiang Yan Shi Dongxin Zhao Song Chen Jun Yong Jing Zhang Tingting Qing Xiaoning Sun Peng Zhang Mingxiao Ding Dongsheng Li Hongkui Deng | 2007 | Cell Research2007，17，4： | 38 |
| 2 | Rock fragmentation mechanisms and an experimental study of drilling tools during high-frequency harmonic vibration显示文摘Resonance drilling is a new technology,still at the laboratory stage.It has great potential to improve rock fragmentation efficiency.We analyzed the amplitude-frequency characteristics of steady-state mechanical vibration excited by harmonic vibration in rocks and an apparatus was built to achieve high frequency vibration of rock.The influence of rock drillability,rotary speed,excitation frequency,and other parameters on the rate of penetration(ROP) in resonance drilling was analyzed.The results show that the rock drillability decreased with an increase in excitation frequency.When drilling with a large size drill bit,the ROP increased with excitation frequency.The ROP reached a maximum value at the resonant frequency of the rock.The ROP of the bit increased linearly with rotary speed when no vibration was applied on the rock and increased approximately exponentially when harmonic vibration was applied.In addition,the resonant frequency of the rock was changing during the process of rock fragmentation,so in order to achieve the desired resonance of the rock,it is necessary to determine an appropriate harmonic vibration excitation frequency. | Li Wei Yan Tie Li Siqi Zhang Xiaoning | 2013 | Petroleum Science2013，10，2： | 9 |
| 3 | Simulation of Morphological Development of Soil Cracks in Yuanmou Dry-hot Valley Region, Southwest China显示文摘Soil cracking is an important process influencing water and solutes transport in the Yuanmou Dry-hot Valley region of Southwest China. Studying the morphological development of soil cracks helps to further reveal the close relationship between the soil cracking process and water movement in such semi-arid regions. Here we report regular changes on surface morphology of soil cracks with decreasing water in four different soils (Typ-Ustic Ferrisols,Ver-Ustic Ferrisols,Tru-Ustic Vertisols and Typ-Ustic Vertisols) through simulation experiments. Our results indicate the following: 1) Different soils ultimately have different development degrees of soil cracks,according to their various values of crack area density. Soil cracks in Typ-Ustic Ferrisols can only develop to the feeble degree,while those in the other three soils are capable of developing into the intensive degree,and even into the extremely intensive degree. 2) Soil crack complexity,as expressed by the value of the area-weighted mean of crack fractal dimension (AWMFRAC),is found to continuously decrease as a whole through the whole cracking process in all the studied soils. 3) Soil crack connectivity shows a uniform trend in the studied soils,that is to say,connectivity gradually increases with soil crack development. | XIONG Donghong YAN Dongchun LONG Yi LU Xiaoning HAN Jianning HAN Xueqin SHI Liangtao | 2010 | Chinese Geographical Science2010，20，2： | 8 |
| 4 | Surface Morphology of Soil Cracks in Yuanmou Dry-hot Valley Region,Southwest China显示文摘Surface morphology of soil cracks is one of the important factors influencing the water evaporation rate in cracked soil in Yuanmou Dry-hot Valley Region,Southwest China. Quantitative study of the complicated surface morphology of soil cracks is a prerequisite for further studies of soil-cracking mechanisms. The present paper establishes a quantitative indicator system by application of concepts and methods originating from Fractal Geometry and Network Analysis. These indicators can effectively express the complicated features of soil-crack network structure. Furthermore,a series of values related to soil-crack morphology was obtained by image processing on field photos of soil-crack quads,and gradation criteria for the degree of development of soil cracks were determined. Finally,the changes in values of the morphological indicators under different degrees of development were analyzed in detail. Our results indicate that (1) the degree of development of soil cracks can be divided into five grades,i.e.,feeble development,slight development,medium development,intensive development and extremely intensive development; (2) the values of the indicators change predictably with increasing degree of development of soil cracks. The area density (Dc) increases,and both the area-weighted mean ratio of crack area to perimeter (AWMARP),which reflects the intensity of cracking,and the index r,which is related to the connectivity of a soil crack,grow uniformly (albeit with different forms). AWMRAP increases at a geometric rate while r shows logarithm-mic growth,indicating a gradual increase in theconnectivity of a soil crack. Nevertheless,the area-weighted mean of soil-crack fractal dimension (AWMFRAC) shows a decreasing trend,indicating a gradual decline in the complexity of cracks as area density increases. | XIONG Donghong LONG Yi YAN Dongchun LU Xiaoning JI Zhonghua FANG Haidong | 2009 | Journal of Mountain Science2009，6，4： | 7 |
| 5 | Curcumin inhibits the replication of enterovirus 71 in vitro显示文摘Human enterovirus 71(EV71)is the main causative pathogen of hand,foot,and mouth disease(HFMD)in children.The epidemic of HFMD has been a public health problem in Asia-Pacific region for decades,and no vaccine and effective antiviral medicine are available.Curcumin has been used as a traditional medicine for centuries to treat a diversity of disorders including viral infections.In this study,we demonstrated that curcumin showed potent antiviral effect again EV71.In Vero cells infected with EV71,the addition of curcumin significantly suppressed the synthesis of viral RNA,the expression of viral protein,and the overall production of viral progeny.Similar with the previous reports,curcumin reduced the production of ROS induced by viral infection.However,the antioxidant property of curcumin did not contribute to its antiviral activity,since N-acetyl-L-cysteine,the potent antioxidant failed to suppress viral replication.This study also showed that extracellular signal-regulated kinase(ERK)was activated by either viral infection or curcumin treatment,but the activated ERK did not interfere with the antiviral effect of curcumin,indicating ERK is not involved in the antiviral mechanism of curcumin.Unlike the previous reports that curcumin inhibited protein degradation through ubiquitin–proteasome system(UPS),we found that curcumin had no impact on UPS in control cells.However,curcumin did reduce the activity of proteasomes which was increased by viral infection.In addition,the accumulation of the short-lived proteins,p53 and p21,was increased by the treatment of curcumin in EV71-infected cells.We further probed the antiviral mechanism of curcumin by examining the expression of GBF1 and PI4KB,both of which are required for the formation of viral replication complex.We found that curcumin significantly reduced the level of both proteins.Moreover,the decreased expression of either GBF1 or PI4KB by the application of siRNAs was sufficient to suppress viral replication.We also demonstrated that curcumin showed anti-apoptotic activity at the early stage of viral infection.The results of this study provide solid evidence that curcumin has potent anti-EV71 activity.Whether or not the down-regulated GBF1 and PI4KB by curcumin contribute to its antiviral effect needs further studies. | Ying Qin Lexun Lin Yang Chen Shuo Wu Xiaoning Si Heng Wu Xia Zhai Yan Wang Lei Tong Bo Pan Xiaoyan Zhong Tianying Wang Wenran Zhao Zhaohua Zhong | 2014 | Acta Pharmaceutica Sinica B2014，4，4： | 5 |
| 6 | Ionomycin ameliorates hypophosphatasia via rescuing alkaline phosphatase deficiency-mediated L-type Ca^(2+) channel internalization in mesenchymal stem cells显示文摘The loss-of-function mutations in the ALPL result in hypophosphatasia(HPP), an inborn metabolic disorder that causes skeletal mineralization defects. In adults, the main clinical features are early loss of primary or secondary teeth, osteoporosis, bone pain,chondrocalcinosis, and fractures. However, guidelines for the treatment of adults with HPP are not available. Here, we show that ALPL deficiency caused a reduction in intracellular Ca2+ influx, resulting in an osteoporotic phenotype due to downregulated osteogenic differentiation and upregulated adipogenic differentiation in both human and mouse bone marrow mesenchymal stem cells(BMSCs). Increasing the intracellular level of calcium in BMSCs by ionomycin treatment rescued the osteoporotic phenotype in alpl+/- mice and BMSC-specific(Prrx1-alpl-/-) conditional alpl knockout mice. Mechanistically, ALPL was found to be required for the maintenance of intracellular Ca2+ influx, which it achieves by regulating L-type Ca2+ channel trafficking via binding to the α2δsubunits to regulate the internalization of the L-type Ca2+ channel. Decreased Ca2+ flux inactivates the Akt/GSK3β/β-catenin signaling pathway, which regulates lineage differentiation of BMSCs. This study identifies a previously unknown role of the ectoenzyme ALPL in the maintenance of calcium channel trafficking to regulate stem cell lineage differentiation and bone homeostasis. Accelerating Ca2+ flux through L-type Ca2+ channels by ionomycin treatment may be a promising therapeutic approach for adult patients with HPP. | Bei Li Xiaoning He Zhiwei Dong Kun Xuan Wei Sun Li Gao Shiyu Liu Wenjia Liu Chenghu Hu Yimin Zhao Songtao Shi Yan Jin | 2020 | Bone Research2020，8，2： | 4 |
| 7 | Molecular dynamics simulation of wetting behavior at CO_2/water/solid interfaces显示文摘We used molecular dynamics simulation to demonstrate the microscopic wetting behavior of two solid model surfaces for the first time.Hydrophilic and hydrophobic features were modeled in a dense CO2 fluid environment under various densities.The water droplet loses contact with the surface under the influence of higher density CO2 fluids on the hydrophobic surface.For the hydrophilic surface,no separation between the water droplet and the surface was observed.However,the contact angle of the water droplet on the hydrophilic surface was found to increase with the fluid density.The effect of dense CO2 fluid on the surface wettability can be interpreted in terms of enhanced interactions from the surrounding CO2 molecules. | LIU ShuYan YANG XiaoNing QIN Yan | 2010 | Chinese Science Bulletin2010，55，21： | 4 |
| 8 | Human endogenous retrovirus W env increases nitric oxide production and enhances the migration ability of microglia by regulating the expression of inducible nitric oxide synthase显示文摘Human endogenous retrovirus W env(HERV-W env) plays a critical role in many neuropsychological diseases such as schizophrenia and multiple sclerosis(MS). These diseases are accompanied by immunological reactions in the central nervous system(CNS). Microglia are important immunocytes in brain inflammation that can produce a gasotransmitter – nitric oxide(NO). NO not only plays a role in the function of neuronal cells but also participates in the pathogenesis of various neuropsychological diseases. In this study, we reported increased NO production in CHME-5 microglia cells after they were transfected with HERV-W env. Moreover, HERV-W env increased the expression and function of human inducible nitric oxide synthase(hi NOS) and enhanced the promoter activity of hi NOS. Microglial migration was also enhanced. These data revealed that HERV-W env might contribute to increase NO production and microglial migration ability in neuropsychological disorders by regulating the expression of inducible NOS. Results from this study might lead to the identification of novel targets for the treatment of neuropsychological diseases, including neuroinflammatory diseases, stroke, and neurodegenerative diseases. | Ran Xiao Shan Li Qian Cao Xiuling Wang Qiujin Yan Xiaoning Tu Ying Zhu Fan Zhu | 2017 | Virologica Sinica2017，32，3： | 3 |
| 9 | Subtyping of type A influenza by sequencing the variable regions of HA gene specifically amplified with RT-PCR显示文摘The outbreak of a novel influenza A(H1N1) virus across the globe poses a threat to human health.It is of paramount importance to develop a rapid,reliable and inexpensive diagnostic procedure.Based on the bioinformatic information from public database,primers specific for influenza A virus surface protein haemagglutinin(HA) of several subtypes(including H1,H2,H3,H5,H7 and H9) were designed.Primer-specific PCR products were subjected to sequencing for accurately distinguishing H1 and H3 subtypes from others.This sequencing-based detection method will not only be applied to rapid detection and simultaneous subtype identification of new influenza A virus H1N1,but also provide the strategies to monitor other new types ofinfluenza virus with explosive potential. | YAN An DING GuoHui ZHOU ZhenFeng DONG Hui ZHANG YaKun ZHU Lei HE YunGang ZHANG GuoQing LI YiXue SUN Bing HUANG Zhong LAN Ke JIN Li WANG HongYan WANG XiaoNing YANG Zhong ZHONG Yang DAI JianXin GUO YaJun WANG Hao CHE XiaoYan WU Fan YUAN ZhenGan ZHANG Xi CAO ZhiWei ZHOU XiaoNong ZHOU JiaHai MA ZhiYong TONG GuangZhi ZHAO GuoPing JIN WeiRong XIONG Hui | 2009 | Chinese Science Bulletin2009，54，13： | 3 |
| 10 | The subsistence patterns of the Shengedaliang site(-4,000 yr BP)revealed by stable carbon and nitrogen isotopes in northern Shaanxi,China显示文摘In order to explore subsistence patterns in northern Shaanxi Province around 4,000 yr BP,28 human and 24 animal bones from the Shengedaliang site were sampled for stable carbon and nitrogen isotope ratio analysis.The results show that most people primarily subsisted on C_4 resources,e.g.millet and millet-related animal products,despite the fact that there was some intake of C_3 plants by some individuals.Stable nitrogen isotope values indicate that there were differences in meat consumption between individuals at the site.Pigs were mainly foddered with millet and millet byproducts,as well as some cattle,according to their highδ^(13)C values.However,most cattle and the sheep/goats consumed wild C_3 plants at Shengedaliang.Our above findings indicates that subsistence patterns in northern Shaanxi around 4,000 yr BP were characterized by millet farming,while the grassland animal husbandry,e.g.cattle and sheep/goats raising,displayed very little contribution to local economy.The intensive millet farming in northern Shaanxi provided enough food for population growth,ensured the accumulation of wealth,and consequently accelerated social differentiation and complexity. | CHEN XiangLong GUO XiaoNing WANG WeiLin HU SongMei YANG MiaoMiao WU Yan HU YaoWu | 2017 | Science China Earth Sciences2017，60，2： | 2 |
| 11 | NUPR1 promotes the proliferation and metastasis of oral squamous cell carcinoma cells by activating TFE3-dependent autophagy显示文摘Oral squamous cell carcinoma(OSCC)is the most common type of oral malignancy,and metastasis accounts for the poor prognosis of OSCC.Autophagy is considered to facilitate OSCC development by mitigating various cellular stresses;nevertheless,the mechanisms of autophagy in OSCC cell proliferation and metastasis remain unknown.In our study,high-sensitivity label-free quantitative proteomics analysis revealed nuclear protein 1(NUPR1)as the most significantly upregulated protein in formalin-fixed paraffin-embedded tumour samples derived from OSCC patients with or without lymphatic metastasis. | Tengfei Fan Xiaoning Wang Sheng Zhang Ping Deng Yi Jiang Yidan Liang Sheng Jie Qing Wang Chuwen Li Guocai Tian Zhen Zhang Zhenhu Ren Bo Li Yanrong Chen Zhijing He Yan Luo Mingliang Chen Hanjiang Wu Zhengping Yu Huifeng Pi Zhou Zhou Zhiyuan Zhang | 2022 | Signal Transduction and Targeted Therapy2022，7，5： | 2 |
| 12 | Effects of Oxymatrine on the NF-kappa B expression of HaCaT cells显示文摘Objective: To study the effect of oxymatrine on the expression of nuclear factor-kappa B(NF-κB) of Human benign epidermal keratinocytes line(HaCaT cells). Methods:HaCaT cells were cultured with different concentration of Oxymatrine(10μg/ml, 50μg/ ml and 100 μg/ml) for 24 h, then 10- mol/L Substance P was added to the cells. After 30 min, NF-κB expression in the cells was 5 observed by immunocytochemistry, NF-κB P65 protein expression was evaluated by Western blot, and the mRNA expression of NF-κB P65 was evaluated by reverse transcription polymerase chain reaction(RT-PCR). The 10- mol/L Substance P and culture medium were 5 added to the Substance P group and control group, respectively. Results:In control group, expression rate of positive cells, the expressions of protein and mRNA of NF-κB were all low. In Substance P group, when 10- mol/L Substance P was added, the expres-sions were all 5 increased(P < 0.05). But in Oxymatrine groups, the expression rate of positive cells, the expressions of protein and mRNA were all descended in a concentration-dependent manner(P < 0.05 or P < 0.01). Conclusion:Oxymatrine can down-regulate the expression of NF-κB of the HaCaT cells and may play an important role in regulating anti-inflammation and immunity. | Caiqing Zhang Jie Feng Xiaoning Yan Wenbing Li Gang Hu | 2008 | Journal of Nanjing Medical University2008，22，3： | 2 |
| 13 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 14 | Evaluating the Impact of Trichoderma brevicompactum 31636 on Root Rot of Atractylodes macrocephala and the Fungal Community in the Rhizosphere Soil显示文摘Background:Trichoderma brevicompactum can control of plant diseases,but there are few studies about the control of root rot by T.brevicompactum 31636 and its biocontrol mechanism.Objective:To explore the impact of T.brevicompactum 31636 on root rot and the structure of fungal communities of rhizosphere soil.Methods:The effect of T.brevicompactum 31636 on controlling root rot was assessed,the growth of plants was observed by pot experiments,and the fungal structure was detected by high-throughput sequencing analysis.Results:Compared with the CK(healthy plants)group,the plant height,fresh weight,and dry weight increased by 55.3%,48.55%and 57.8%,respectively.While the concentration of atractylenolideⅠ,Ⅱ,Ⅲ,and atractylone increased by 19.35%,16.96%,89.42%and 89.32%,respectively.The results of pot experiments indicated that T.brevicompactum 31636 could significantly improve the survival rate of Atractylodes macrocephala.The results of principal coordinates analysis(PCoA)showed that the sample of CK and Fo+Th(adding Fusdrium oxysporum before T.brevicompactum 31636)group on one side,and samples of Th and Fo group on the other.Furthermore,among the top 20 dominant fungi detected,the fungal genus with 1%increase of relative abundance included Trichoderma(1%),Sordariomycetes(1.5%),Mortierella(1.3%),Penicillium(1%),meanwhile the fungal genus with 1%decrease of relative abundance included Fusarium(30%)and Pleosporales(1%).Conclusion:In summary,T.brevicompactum 31636 can control the root rot of A.macrocephala by regulating of the soil fungal community and inhibiting pathogen. | Xingge Huang Xiaoning Yan Yunjia Tang Xiaofeng Yuan | 2022 | Clinical Complementary Medicine and Pharmacology2022，2，4： | 1 |
| 15 | Synthesis and characterization of high density and high aspect ratio Ag_2S nanoparticle nanowires from a paired cell method显示文摘Ag_2S nanoparticle nanowires were prepared in a porous anodic aluminum oxide template by a simple paired cell method,and were characterized by XRD,FESEM,HRTEM and EDS.The results showed that the as-prepared nanowires were composed of monoclinic Ag_2S nanoparticles.The nanowire diameters ranged from 165 to 270 nm,and Ag_2S nanoparticles were nearly spherical with diameters of 40 to 60 nm.The paired cell method is simple,low cost and easy to control for the fabrication of high density and high aspect ratio Ag_2S nanoparticle nanowires.A formation mechanism for the nanoparticle nanowires was suggested. | LI XiaoNing YANG XiuChun HAN ShanShan LU Wei HOU JunWei LIU Yan | 2011 | Chinese Science Bulletin2011，56，17： | 1 |
| 16 | Saving face or sharing personal information? a crosscultural study on knowledge sharing显示文摘 | Qiping Zhang Chintakovid Xiaoning Sun Yan Ge Kan Zhang | 2006 | Journal of Information & Knowledge Management2006，5，1： | 1 |
| 17 | Biochemical characterization of human peroxiredoxin 2, an antioxidative protein显示文摘人的 peroxiredoxin 2 (Prx2 ) ,它充满红血球,被显示了在由清除保护红血球免于氧化应力起一个关键作用象参予房间信号 transduction 一样的反应的氧种类。这里,人的 Prx2 基因成功地为 Prx2 表示被克隆进 Escherichia coli BL21 (DE3 ) 。钠 dodecyl 硫酸盐 polyacrylamide 胶化电气泳动分析建议 recombinant 蛋白质主要在一种可溶的形式被表示。recombinant 蛋白质被一步舞 Ni-nitrilotriacetic 酸 chelating 亲密关系层析净化到多达 91.5% 的纯净。Prx2 的 peroxidase 活动 H2O2 被 ferrithiocyanate 试金决定清除。Prx2 的能力被使用一个混合功能氧化系统测试保护 plasmid DNA,并且结果证明 Prx2 能阻止 DNA 经历氧化应力。紫外(紫外) 导致的房间 apoptosis 试金证明 Prx2 也能保护 NIH/3T3 房间免受紫外导致损坏的伤害,在化妆品和另外的区域建议它的可能的应用。 | Sheng Yan Shaopei Chen Zhendong Li Haiying Wang Tuxiong Huang Xiaoning Wang Jufang Wang | 2012 | Acta Biochimica et Biophysica Sinica2012，44，9： | 1 |
| 18 | 查看详情显示文摘 | Zhang Bin Lin Yan Tang XiaoNing | | 0，，： | 1 |
| 19 | A Molecular Foaming and Activation Strategy to Porous N-Doped Carbon Foams for Supercapacitors and CO2 Capture显示文摘Hierarchically porous carbon materials are promising for energy storage,separation and catalysis.It is desirable but fairly challenging to simultaneously create ultrahigh surface areas,large pore volumes and high N contents in these materials.Herein,we demonstrate a facile acid-base enabled in situ molecular foaming and activation strategy for the synthesis of hierarchically macro-/meso-/microporous N-doped carbon foams(HPNCFs).The key design for the synthesis is the selection of histidine(His)and potassium bicarbonate(PBC)to allow the formation of 3D foam structures by in situ foaming,the PBC/His acid-base reaction to enable a molecular mixing and subsequent a uniform chemical activation,and the stable imidazole moiety in His to sustain high N contents after carbonization.The formation mechanism of the HPNCFs is studied in detail.The prepared HPNCFs possess 3D macroporous frameworks with thin well-graphitized carbon walls,ultrahigh surface areas(up to 3200 m^2 g^-1),large pore volumes(up to 2.0 cm^3 g^-1),high micropore volumes(up to 0.67 cm^3 g^-1),narrowly distributed micropores and mesopores and high N contents(up to 14.6 wt%)with pyrrolic N as the predominant N site.The HPNCFs are promising for supercapacitors with high specific capacitances(185-240 F g^-1),good rate capability and excellent stability.They are also excellent for CO2 capture with a high adsorption capacity(~4.13 mmol g^-1),a large isosteric heat of adsorption(26.5 kJ mol^-1)and an excellent CO2/N2 selectivity(~24). | Mengyuan Zhou Yaqian Lin Huayao Xia Xiangru Wei Yan Yao Xiaoning Wang Zhangxiong Wu | 2020 | Nano-Micro Letters2020，12，5： | 1 |
| 20 | Effect of Fillers on the Pavement Performance of Asphalt Binder显示文摘 | Zou Guilian Yuan Yan Zhang Xiaoning | 2005 | Journal of South China University of Technology (Natural Science Edition)2005，33，1： | 1 |
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