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| 1 | Epidemiology of Diabetes in Adults Aged 35 and Older from Shanghai,China显示文摘Objective This study aimed to investigate the epidemiology of diabetes in adults from Shanghai, aged 35 and older, in 2013. Methods We estimated the diabetes prevalence in a representative sample of 18,736 adults who were selected through a multistage stratified cluster sampling process. A standard questionnaire containing questions about demographic characteristics and lifestyle factors was distributed. After an overnight fast of at least 10 hours, a venous blood sample was collected from each participant. For each patient without a history of diabetes, another blood sample was drawn 120 min after an oral glucose tolerance test to identify undiagnosed diabetes and prediabetic condition. Results Among Shanghai residents aged 35 and above, the overall weighted prevalence of diabetes was 17.6% [95% confidence interval(CI): 16.4%-18.8%]. The prevalences were 19.3% in men and 15.8% in women as well as 19.1%, 15.4%, and 16.1% in urban, suburban, and rural residents, respectively. In addition, the weighted prevalence of prediabetes was 16.5%(95% CI: 15.3%-17.8%), with the prevalences of 16.5% in men, 16.6% in women, 15.2% in urban residents, 18.0% in suburban residents, and 18.5% in rural residents. Among all patients with diabetes, 68.1%(95% CI: 64.3%-71.6%) were aware of their status, 63.5%(95% CI: 60.0%-66.9%) received diabetes treatment, but only 35.1%(95% CI: 32.4%-37.8%) had adequate glycemic control. Conclusion In Shanghai, diabetes and prediabetes are highly prevalent. However, 1/3rd of diabetes cases are undiagnosed, and the rate of glycemic control is low. | RUAN Ye YAN Qing Hua XU Ji Ying YANG Qun Di YAO Hai Hong LI Rui SHI Yan | 2016 | Biomedical and Environmental Sciences2016，29，6： | 22 |
| 2 | Secukinumab demonstrates high efficacy and a favorable safety profile over 52 weeks in Chinese patients with moderate to severe plaque psoriasis显示文摘Background:Psoriasis is a chronic inflammatory skin disease,affecting about 0.6%of the Chinese population.Many patients are not well controlled by conventional treatments,thus there is need for new treatment regimens.In this study,we assessed the efficacy and safety of secukinumab in Chinese patients with moderate to severe plaque psoriasis.Methods:This study was a 52-week,multicentre,randomized,double-blind,placebo-controlled,parallel-group,Phase 3 trial.A sub-population of study participants(≥18 years)of Chinese ethnicity were randomized to receive subcutaneous injections of 300 or 150 mg secukinumab,or placebo.The co-primary endpoints were psoriasis area severity index(PASI)75 and Investigator’s Global Assessment(IGA)0/1 at Week 12.Results:A total of 441 Chinese patients were enrolled in this study.Co-primary outcomes were achieved;300 and 150 mg secukinumab were superior to placebo as shown in the proportion of patients that achieved PASI 75(97.7%and 87.2%vs.3.7%,respectively;P<0.001),and IGA 0/1(82.3%and 69.7%vs.2.7%;P<0.001)at Week 12.Treatment efficacy was maintained until Week 52.There was no increase in overall adverse events with secukinumab relative to placebo throughout the 52-week period.Conclusion:Secukinumab is highly effective and well tolerated in Chinese patients with moderate to severe plaque psoriasis. | Lin Cai Jian-Zhong Zhang Xu Yao Jun Gu Quan-Zhong Liu Min Zheng Shi-Fa Zhang Jin-Hua Xu Cheng-Xin Li Hao Cheng Qing Guo Wei-Li Pan Shen-Qiu Li Ruo-Yu Li Zai-Pei Guo Zhi-Qi Song Shan-Shan Li Xiu-Qin Dong Linda Wang Rong Fu Pascaline Regnault Pascal Charef Ratal Mazur Manmath Patekar | 2020 | Chinese Medical Journal2020，，22： | 21 |
| 3 | Regeneration of 2-amino-2-methyl-1-propanol used for carbon dioxide absorption显示文摘为了改进二氧化碳的效率骑车,处理并且减少新生能量消耗,一个位的联盟者妨碍了 2-amino-2-methyl-1-propranol (安培) 的胺被调查作为 CO2 吸收剂决定它的新生行为。CO2 吸收和胺新生特征试验性地在各种各样的操作条件下面被检验。新生效率在 358 ~ 403 K 的温度范围期间从 86.2% ~ 98.3% 增加了。为安培的最合适的新生温度是 383 K,处于这个实验条件,并且吸收 / 新生的新生效率变从 98.3% ~ 94.0% 下降了。很多热马厩盐(HSS ) 能在 CO2 吸收容量和新生效率引起减小。结果显示水的安培更容易比另外的胺与吸收容量的更少的损失再生,例如,单音的乙醇胺(MEA ) , diethanolamine (DEA ) , diethylenetriamine (DETA ) ,和 N-methyldiethanolamine (MDEA ) 。 | ZHANG Pei SHI Yao WEI Jianwen ZHAO Wei YE Qing | 2008 | Journal of Environmental Sciences2008，20，1： | 21 |
| 4 | An Insect Imaging System to Automate Rice Light-Trap Pest Identification显示文摘Identification and counting of rice light-trap pests are important to monitor rice pest population dynamics and make pest forecast. Identification and counting of rice light-trap pests manually is time-consuming, and leads to fatigue and an increase in the error rate. A rice light-trap insect imaging system is developed to automate rice pest identification. This system can capture the top and bottom images of each insect by two cameras to obtain more image features. A method is proposed for removing the background by color difference of two images with pests and non-pests. 156 features including color, shape and texture features of each pest are extracted into an support vector machine (SVM) classifier with radial basis kernel function. The seven-fold cross-validation is used to improve the accurate rate of pest identification. Four species of Lepidoptera rice pests are tested and achieved 97.5% average accurate rate. | YAO Qing LV Jun LIU Qing-jie DIAO Guang-qiang YANG Bao-jun CHEN Hong-ming TANGJian | 2012 | Journal of Integrative Agriculture2012，11，6： | 21 |
| 5 | Expression changes and bioinformatic analysis of Wallerian degeneration after sciatic nerve injury in rat显示文摘Wallerian degeneration (WD) remains an important research topic. Many genes are differentially expressed during the process of WD, but the precise mechanisms responsible for these differentiations are not completely understood. In this study, we used microarrays to analyze the expression changes of the distal nerve stump at 0, 1, 4, 7, 14, 21 and 28 days after sciatic nerve injury in rats. The data revealed 6 076 differentially-expressed genes, with 23 types of expression, specifically enriched in genes associated with nerve development and axonogenesis, cytokine biosynthesis, cell differentiation, cytokine/chemokine production, neuron differentiation, cytokinesis, phosphorylation and axon regeneration. Kyoto Encyclopedia of Genes and Genomes pathway analysis gave findings related mainly to the MAPK signaling pathway, the Jak-STAT signaling pathway, the cell cycle, cytokine-cytokine receptor interaction, the p53 signaling pathway and the Wnt signaling pathway. Some key factors were NGF, MAG, CNTF, CTNNA2, p53, JAK2, PLCB1, STAT3, BDNF, PRKC, collagen II, FGF, THBS4, TNC and c-Src, which were further validated by real-time quantitative PCR, Western blot, and immunohistochemistry. Our findings contribute to a better understanding of the functional analysis of differentially-expressed genes in WD and may shed light on the molecular mechanisms of nerve degeneration and regeneration. | Dengbing Yao Meiyuan Li Dingding Shen Fei Ding Shibi Lu Qing Zhao Xiaosong Gu | 2013 | Neuroscience Bulletin2013，29，3： | 18 |
| 6 | Automated Counting of Rice Planthoppers in Paddy Fields Based on Image Processing显示文摘A quantitative survey of rice planthoppers in paddy fields is important to assess the population density and make forecasting decisions. Manual rice planthopper survey methods in paddy fields are time-consuming, fatiguing and tedious. This paper describes a handheld device for easily capturing planthopper images on rice stems and an automatic method for counting rice planthoppers based on image processing. The handheld device consists of a digital camera with WiFi, a smartphone and an extrendable pole. The surveyor can use the smartphone to control the camera, which is fixed on the front of the pole by WiFi, and to photograph planthoppers on rice stems. For the counting of planthoppers on rice stems, we adopt three layers of detection that involve the following:(a) the first layer of detection is an AdaBoost classifier based on Haar features;(b) the second layer of detection is a support vector machine(SVM) classifier based on histogram of oriented gradient(HOG) features;(c) the third layer of detection is the threshold judgment of the three features. We use this method to detect and count whiteback planthoppers(Sogatella furcifera) on rice plant images and achieve an 85.2% detection rate and a 9.6% false detection rate. The method is easy, rapid and accurate for the assessment of the population density of rice planthoppers in paddy fields. | YAO Qing XIAN Ding-xiang LIU Qing-jie YANG Bao-jun DIAO Guang-qiang TANG Jian | 2014 | Journal of Integrative Agriculture2014，13，8： | 18 |
| 7 | Geographical characteristics of China’s wetlands derived from remotely sensed data显示文摘In this paper, we report the first wetland mapping of the entire China using Landsat enhanced thematic mapper plus (ETM+) data. These data were obtained from the Global Land Cover Facility at the University of Maryland spanning from 1999 to 2002. A total of 597 scenes of Landsat images were georeferenced and mosaiced. Manual image interpretation of satellite images was aided with elevation data, soil data, land cover/land use data and Google Earth. The minimum mapping unit is 10 pixel × 10 pixel, equivalent to 9 ha. The aim of our first round of mapping was only targeted at the boundary delineation of any type of wetland except those wetlands that are under agricultural use (i.e., paddy fields), which has already been well mapped by others. Our interpretation results indicate that a total of 359478 km2 of wetlands are of non-agricultural use. Among our preliminarily mapped wetland, 339353 km2 are inland wetland, 2786 km2 are non-agricultural artificial wetland, and 17609 km2 are coastal wetland. Because low-tide is rarely captured in satellite images, an under-estimation of coastal wetland is inevitable. We conducted some statistics based on our mapped wetlands and compared them with those previously obtained from a number of sources including a land cover/land use map made with satellite images during the late 1990s and early 2000s, a marshland map developed in approximately the same period, survey data of coastal wetland in early 1980s, and area data for approximately 400 larger patches of marshland in China compiled in 1996. Because some inconsistencies exist in the guidelines of those different wetland surveys, difference in area is expected. Some further comparison indicates that the wetland distributions derived from the preliminary wetland map are reasonable and more objective than other sources. The mapping process also indicated that the method adopted by us was efficient and cost-effective. We also found that in order to ensure comparability of the wetland maps developed at different times, a set of standard guidelines on the wetland categories to be mapped, and the mapping methods to be used must be well conceived, developed and effectively employed. We carried out some initial geographical analysis on the distribution of wetlands. | NIU ZhenGuo GONG Peng CHENG Xiao GUO JianHong WANG Lin HUANG HuaBing SHEN ShaoQing WU YunZhao WANG XiaoFeng WANG XianWei YING Qing LIANG Lu ZHANG LiNa WANG Lei YAO Qian YANG ZhenZhong GUO ZiQi DAI YongJiu | 2009 | Science China Earth Sciences2009，52，6： | 15 |
| 8 | Fault zone structures of northern and southern portions of the main central fault generated by the 2008 Wenchuan earthquake using fault zone trapped waves显示文摘The rupture process of the May 12,2008 MS8.0 Wenchuan earthquake was very complex. To study the rupture zones generated by this earthquake,four dense temporary seismic arrays across the two surface breaking traces of the main-shock were deployed in July and recorded a great amount of aftershocks. This paper focuses on the data interpretation of two arrays across the central main fault,the northern array line 1 and southern array line 3. The fault zone trapped waves recorded by the two arrays were used to study the structure of the central main fault and the difference between the northern and southern portions. The results show that the widths of the rupture zone are about 170?200 m and 200?230 m for northern and southern portions respectively. And the corresponding dip angles are 80° and 70°. The seismic velocity inside the fracture zone is about one half of the host rock. By comparison,the northern portion of the rupture zone is slightly narrower and steeper than the southern portion. Besides these differences,one more interesting and important difference is the positions of the rupture zone with respect to surface breaking traces. At the northern portion,the rupture zone is centered at the surface breaking trace,while at the southern portion it is not but is shifted to the northwest. This difference reflects the difference of rupture behaviors between two portions of the central main fault. The width of the rupture zone is smaller than that of M8.1 Kunlun earthquake though these two earthquakes have almost the same magnitudes. Multiple ruptures may be one factor to cause the narrower rupture zone. | Songlin Li Xiaoling Lai Zhixiang Yao Qing Yang | 2009 | Earthquake Science2009，22，4： | 14 |
| 9 | Nat Microbiol:已结首次构建出小鼠肠道微生物组数据库显示文摘小鼠模型通常被广泛用于药理学和医学研究。我们都知道小鼠肠道中的微生物群落通常会对研究结果产生明显的影响,然而目前研究者们并没有获取到关于小鼠肠道中栖息细菌群落的详细信息。近日刊登在国际杂志Nature Microbiology上的一篇研究报告中。德国慕尼黑理工大学的研究者通过研究首次收集到了小鼠肠道中的多种细菌群落。同时研究者还对其进行了分裂、特性分析。最后得到了100种细菌,其中还包括15种迄今为止未知的细菌群落。 | Lu, Qiulun Yao, Yufeng Hu, Zhenkun Hu, Changqing Song, Qixue Ye, Jian Xu, Chengqi Wang, Annabel Z. Chen, Qiuyun Wang, Qing Kenneth | 2016 | 现代生物医学进展2016，16，32： | 13 |
| 10 | Automated detection and identification of white-backed planthoppers in paddy fields using image processing显示文摘A survey of the population densities of rice planthoppers is important for forecasting decisions and efficient control. Traditional manual surveying of rice planthoppers is time-consuming, fatiguing, and subjective. A new three-layer detection method was proposed to detect and identify white-backed planthoppers(WBPHs, Sogatella furcifera(Horváth)) and their developmental stages using image processing. In the first two detection layers, we used an Ada Boost classifier that was trained on a histogram of oriented gradient(HOG) features and a support vector machine(SVM) classifier that was trained on Gabor and Local Binary Pattern(LBP) features to detect WBPHs and remove impurities. We achieved a detection rate of 85.6% and a false detection rate of 10.2%. In the third detection layer, a SVM classifier that was trained on the HOG features was used to identify the different developmental stages of the WBPHs, and we achieved an identification rate of 73.1%, a false identification rate of 23.3%, and a 5.6% false detection rate for the images without WBPHs. The proposed three-layer detection method is feasible and effective for the identification of different developmental stages of planthoppers on rice plants in paddy fields. | YAO Qing CHEN Guo-te WANG Zheng ZHANG Chao YANG Bao-jun TANG Jian | 2017 | Journal of Integrative Agriculture2017，16，7： | 13 |
| 11 | Effect of human umbilical cord-derived mesenchymal stem cells on lung damage in severe COVID-19 patients:a randomized,double-blind,placebo-controlled phase 2 trial显示文摘Treatment of severe Coronavirus Disease 2019(COVID-19)is challenging.We performed a phase 2 trial to assess the efficacy andsafety of human umbilical cord-mesenchymal stem cells(UC-MScs)to treat severe coViD-19 patients with lung damage,based onour phase 1 data.In this randomized,double-blind,and placebo-controlled trial,we recruited 101 severe coVID-19 patients withlung damage.They were randomly assigned at a 2:1 ratio to receive either UC-MSCs(4×10^(7)cells per infusion)or placebo on day 0,3,and 6.The primary endpoint was an altered proportion of whole lung lesion volumes from baseline to day 28.Other imagingoutcomes,6-minute walk test(6-MWT),maximum vital capacity,diffusing capacity,and adverse events were recorded and analyzed.In all,100 COVID-19 patients were finally received either UC-MSCs in=65)or placebo(n=35).UC-MSCs administrationexerted numerical improvement in whole lung lesion volume from baseline to day 28 compared with the placebo(the mediandifference was-13.31%,95%Cl-29.14%,2.13%,P=0.08).UC-MSCs significanty reduced the proportions of solid componentlesion volume compared with the placebo(median difference:-15.45%;95%CI-30.82%,-0.39%;P=0.043).The 6-MWT showedan increased distance in patients treated with UC-MSCs(difference:27.00 m;95%CI 0.00,57.00;P=0.057).The incidence of adverseevents was similar in the two groups.These results suggest that UC-MSCs treatment is a safe and potentially effective therapeuticapproach for COVID-19 patients with lung damage.A phase 3 trial is required to evaluate effects on reducing mortality andpreventing long-term pulmonary disability. | Lei Shi Hai Huang Xuechun Lu Xiaoyan Yan Xiaojing Jiang Ruonan Xu Siyu Wang Chao Zhang Xin Yuan Zhe Xu Lei Huang Jun-Liang Fu Yuanyuan Li Yu Zhang Wei-Qi Yao Tianyi Liu Jinwen Song Liangliang Sun Fan Yang Xin Zhang Bo Zhang Ming Shi Fanping Meng Yanning Song Yongpei Yu Jiqiu Wen Qi Li Qing Mao Markus Maeurer Alimuddin Zumla Chen Yao Wei-Fen Xie Fu-Sheng Wang | 2021 | Signal Transduction and Targeted Therapy2021，6，3： | 13 |
| 12 | Treatment of hepatoma with liposome-encapsulated adriamycin administered into hepatic artery of rats显示文摘瞄准:加空白与 adriamycin 答案(FADM ) 和 adriamycin 比较在肝细胞瘤上观察包含 liposome 的 adriamycin (LADM ) 的治疗学的效果脂肪一些(ADM + BL ) 管理了进老鼠的肝的动脉。方法:LADM 被 pH 准备坡度驱动的方法。生理盐水, FADM (2 mg/kg ) , ADM+BL (2 mg/kg ) ,和 LADM (2 mg/kg ) 在忍受肝 W256 癌肉瘤的老鼠经由肝的动脉被注射,它随机被划分成四个组。治疗学的效果以生存时间,肿瘤增大比率,和肿瘤坏死度被评估。差别与 ANOVA 和 Dunnett 测试和木头等级测试被决定。结果:比作 FADM 或 ADM + BL, LADM 生产了更重要的肿瘤抑制(肿瘤体积比率:1.243 +/- 0.523 对 1.883 +/- 0.708, 1.847 +/- 0.661, P <
0.01 ) ,并且更广泛的肿瘤坏死。增加的寿命在与 FADM 或 ADM+BL 相比收到 LADM 的老鼠显著地被延长(231.48 对 74.66, 94.70 )(P <
0.05 ) 。结论:肝细胞瘤上的 adriamycin 的反癌症功效能被 liposomal 封装强烈通过肝的动脉的管理改进。 | Dong-Sheng Sun Jiang-Hao Chen Rui Ling Qing Yao Ling Wang Zhong Ma Yu Li | 2006 | World Journal of Gastroenterology2006，12，29： | 13 |
| 13 | Determination of Anthocyanins and Exploration of Relationship between Their Composition and Petal Coloration in Crape Myrtle (Lagerstroemia hybrid)显示文摘Petal coloration and pigment components in 12 American crape myrtle cultivars (Lagerstroemia indica × Lagerstroemia fauriei) and five Chinese crape myrtle cultivars (L. indica hybrids) were studied. Color was measured by CIEL*a*b* scale and anthocyanin composition of crape myrtle was determined using high-performance liquid chromatography coupled to photodiode array detection and electrospray ionization mass spectrometry. The presence of the previously reported delphinidin 3-O-glucoside,petunidin 3-O-glucoside and malvidin 3-O-glucoside were confirmed. Cyanidin 3-O-glucoside was identified in crape myrtle for the first time. We explored the relationship between petal color and anthocyanin contents by multiple linear regression analyses. The results indicated that total flavones and flavonols were important variables and contributed to blue-enhancing in crape myrtle. Based on anthocyanins and co-pigments analysis,flower color breeding in crape myrtle towards true-red and blue were discussed. | Jie Zhang Liang-Sheng Wang Jin-Ming Gao Qing-Yan Shu Chong-Hui Li Juan Yao Qing Hao Jing-Jing Zhang | 2008 | Journal of Integrative Plant Biology2008，50，5： | 12 |
| 14 | Existence,Multiplicity and Infinite Solvability of Positive Solutions for One-Dimensional p-Laplacian显示文摘存在,复合和积极答案的无限的解决之可能性为一个维的 p 拉普拉斯算符的一些二点的边界价值问题被建立。在这篇论文,由复合,我们意味着 m 答案的存在,在 m 是一个任意的自然数字的地方。 | Qing Liu YAO | 2005 | Acta Mathematica Sinica,English Series2005，21，4： | 12 |
| 15 | Osteoarthritis:pathogenic signaling pathways and therapeutic targets显示文摘Osteoarthritis(OA)is a chronic degenerative joint disorder that leads to disability and affects more than 500 million population worldwide.OA was believed to be caused by the wearing and tearing of articular cartilage,but it is now more commonly referred to as a chronic whole-joint disorder that is initiated with biochemical and cellular alterations in the synovial joint tissues,which leads to the histological and structural changes of the joint and ends up with the whole tissue dysfunction.Currently,there is no cure for OA,partly due to a lack of comprehensive understanding of the pathological mechanism of the initiation and progression of the disease.Therefore,a better understanding of pathological signaling pathways and key molecules involved in OA pathogenesis is crucial for therapeutic target design and drug development.In this review,we first summarize the epidemiology of OA,including its prevalence,incidence and burdens,and OA risk factors.We then focus on the roles and regulation of the pathological signaling pathways,such as Wnt/β-catenin,NF-κB,focal adhesion,HIFs,TGFβ/ΒΜP and FGF signaling pathways,and key regulators AMPK,mTOR,and RUNX2 in the onset and development of OA.In addition,the roles of factors associated with OA,including MMPs,ADAMTS/ADAMs,and PRG4,are discussed in detail.Finally,we provide updates on the current clinical therapies and clinical trials of biological treatments and drugs for OA.Research advances in basic knowledge of articular cartilage biology and OA pathogenesis will have a significant impact and translational value in developing OA therapeutic strategies. | Qing Yao Xiaohao Wu Chu Tao Weiyuan Gong Mingjue Chen Minghao Qu Yiming Zhong Tailin He Sheng Chen Guozhi Xiao | 2023 | Signal Transduction and Targeted Therapy2023，8，3： | 11 |
| 16 | Multifunctional lymph-targeted platform based Mn@mSiO2 nanocomposites: Combining PFOB dual-mode imaging and DOX for cancer diagnose treatment on for and显示文摘 | Tian Liu Guangyu Wu Jiejun Cheng Qing Lu Yanjie Yao Zhenjing Liu Dongchen Zhu Juan Zhou Jianrong Xu Jun Zhu Dannong He | 2016 | Nano Research2016，9，2： | 11 |
| 17 | Biallelic mutations in CDC20 cause female infertility characterized by abnormalities in oocyte maturation and early embryonic development显示文摘Dear Editor,Previously,the Mendelian phe no types in huma n oocyte maturation arrest,fertilization failure and early embryonic arrest,are largely underestimated.In recent years,'missing'Men delian phe no types and genes in these processes are beginning to be uncovered by us and others(Huang et al.,2014;Alazami et al..2015;Feng et al.,2016;Xu et al.,2016;Chen et al.,2017;Sang et al.,2019).However,the genetic basis for majority of patients resulting from abnormalities in these phe no types remains to be elucidated. | Lin Zhao Songguo Xue Zhongyuan Yao Juanzi Shi Biaobang Chen Ling Wu Lihua Sun Yao Xu Zheng Yan Bin Li Xiaoyan Mao Jing Fu Zhihua Zhang Jian Mu Wenjing Wang Jing Du Shuai Liu Jie Dong Weijie Wang Qiaoli Li Lin He Li Jin Xiaozhen Liang Yanping Kuang Xiaoxi Sun Lei Wang Qing Sang | 2020 | Protein & Cell2020，11，12： | 10 |
| 18 | Proportion of Uterine Malignant Tumors in Patients with Laparoscopic Myomectomy: A National Multicenter Study in China显示文摘 | Hua Yang Xiao-Chuan Li Chen Yao Jing-He Lang Hang-Mei Jin Ming-Rong Xi Gang Wang Lu-Wen Wang Min Hao Yan Ding Jie Chen Jian-Qing Zhang Lu Han Cheng-Xiu Guo Xiang Xue Yan Li Jian-Hua Zheng Man-Hua Cui Huai-Fang Li Guang-Shi Tao Long Chen Su-Min Wang An-Wei LU Ze-Hua Huang Qing Liu Ya-Li Zhuang Xiang-Hua Huang Gen-Hai Zhu Ou-Ping Huang Li-Na Hu Mu-Jun Li Hong-Lin Zhou Jing-Hui Song Lan Zhu | 2017 | Chinese Medical Journal2017，，22： | 10 |
| 19 | Study on Female Sexual Dysfunction in Type 2 Diabetic Chinese Women显示文摘Objective To investigate the female sexual dysfunction (FSD) in type 2 diabetes patients, by comparing the sexual function between type 2 diabetic women and non-diabetic women with Female Sexual Function Index (FSFI). Methods 115 type 2 diabetic women and 107 age-matched non-diabetes women were enrolled with similar backgrounds. Their sexual functions were evaluated with FSFI. Metabolic parameters such as body mass index, blood lipid profile, hemoglobin A1C, plasma glucose were also collected. Results Total score of FSFI of the type 2 diabetic women were significantly lower than that of the non-diabetic controls (18.27±8.96 vs. 23.02±5.78, P=0.000). Scores of the FSFI domains (desire, arousal, lubrication, orgasm, satisfaction, pain) of the type 2 diabetic group were also lower than those of the control group. According to the FSD criterion (FSFI<25) available in China, the percentage of FSD in the type 2 diabetic group was significantly higher than that of the control group (79.2% vs. 55.0%, P<0.001). These trends seemed more prominent in pre-menopause subgroups. The logistic regression analysis indicated that age and diabetes were independent risk factors of FSD. Body Mass Index (BMI) also had influence in the diabetes group. Conclusion Findings from this study showed that there are more FDS in Chinese type 2 diabetic women than in their non-diabetic counterparts, especially in pre-menopause participants. | SHI Yao Fang SHAO Xin Yu LOU Qing Qing CHEN Ya Juan ZHOU Hui Juan ZOU Jian Ying | 2012 | Biomedical and Environmental Sciences2012，25，5： | 10 |
| 20 | Mechanical properties and characteristics of nanometer-sized precipitates in hot-rolled low-carbon ferritic steel显示文摘The microstructures and properties of hot-rolled low-carbon ferritic steel have been investigated by optical microscopy, field-emission scanning electron microscopy, transmission electron microscopy, and tensile tests after isothermal transformation from 600°C to 700°C for 60 min. It is found that the strength of the steel decreases with the increment of isothermal temperature, whereas the hole expansion ratio and the fraction of high-angle grain boundaries increase. A large amount of nanometer-sized carbides were homogeneously distributed throughout the material, and fine(Ti, Mo)C precipitates have a significant precipitation strengthening effect on the ferrite phase because of their high density. The nanometer-sized carbides have a lattice parameter of 0.411-0.431 nm. After isothermal transformation at 650°C for 60 min, the ferrite phase can be strengthened above 300 MPa by precipitation strengthening according to the Ashby-Orowan mechanism. | Xiao-pei Wang Ai-min Zhao Zheng-zhi Zhao Yao Huang Liang Li Qing He | 2014 | International Journal of Minerals,Metallurgy and Materials2014，21，3： | 9 |
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