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| 1 | Chinese Outward Direct Investment:Is There a China Model?显示文摘中国向外直接的投资(ODI ) 看起来不同于先进经济的。有一个唯一的中国模型吗?由为 20032009 考察 ODI 数据的工业分布,我们发现中国 ODI 没在在出口或国内表现了很好的工业被集中。统计分析也证实传统的变量例如市场尺寸,生产费用和法律环境,没为 ODI 影响中国投资者地点的选择。相反,投资者选择了他们也能学习先进技术或安全稳定的商品供应的地方。我们尝试性地断定 ODI 的中国模型的主要目的一直不是扩展海外的生产,但是在家加强工业。 | Yiping Huang Bijun Wang | 2011 | China & World Economy2011，19，4： | 22 |
| 2 | Effect of carbon addition on the microstructure and mechanical properties of CoCrFeNi high entropy alloy显示文摘The effects of C element on the microstructure and properties of CoCrFeNiCx high entropy alloys(x denoted the atomic fraction of C element at 0, 0.05, 0.1, 0.2, 0.3, and 0.5) were investigated. The equal molar CoCrFeNi alloy with FCC structure exhibits high ductility but weak strength. With the addition of C element, both the hardness and strength of the CoCrFeNiCx high entropy alloys increase as well as the wear resistance. The solution strengthening and the formation of hard carbide phase are the main factor for the improved strength, hardness and wear resistance of CoCrFeNiCx high entropy alloys. | HUANG TianDang JIANG Li ZHANG ChangLiang JIANG Hui LU YiPing LI TingJu | 2018 | Science China(Technological Sciences)2018，61，1： | 22 |
| 3 | A promising new class of irradiation tolerant materials:Ti_2ZrHfV_(0.5)Mo_(0.2) high-entropy alloy显示文摘Recently, high-entropy alloys(HEAs) or multi-principal-element alloys with unprecedented physical,chemical, and mechanical properties, have been considered as candidate materials used in advanced reactors due to their promising irradiation resistant behavior. Here, we report a new single-phase bodycentered cubic(BCC) structured Ti_2 ZrHfV_(0.5)Mo_(0.2) HEA possessing excellent irradiation resistance, i.e.,scarcely irradiation hardening and abnormal lattice constant reduction after helium-ion irradiation,which is completely different from conventional alloys. This is the first time to report the abnormal XRD phenomenon of metallic alloys and almost no hardening after irradiation. These excellent properties make it to be a potential candidate material used as core components in next-generation nuclear reactors. The particular irradiation tolerance derives from high density lattice vacancies/defects. | Yiping Lu Hefei Huang Xuzhou Gao Cuilan Ren Jie Gao Huanzhi Zhang Shijian Zheng Qianqian Jin Yonghao Zhao Chenyang Lu Tongmin Wang Tingju Li | 2019 | Journal of Materials Science & Technology2019，35，3： | 23 |
| 4 | 高渗氯化钠溶液治疗失血性休克的实验研究显示文摘目的 筛选出最佳氯化钠溶液浓度、最佳滴注速度和最佳剂量 ;了解高渗氯化钠溶液复苏后血浆渗透压及电解质的变化情况。 方法 45只犬 ,制成失血性休克模型 ,用不同浓度和剂量的氯化钠溶液在不同滴注速度下 ,对失血性休克犬进行复苏 ,比较其复苏效果。 结果 质量浓度为 75g/L的高渗氯化钠溶液为最佳浓度 ,2 0ml/min为最佳滴速 ,相当于放血量的 15 %(5 .71mg/kg体重 )为最佳剂量 ;复苏效果确切 ,使平均动脉压恢复到基础水平的 89% ,且维持时间至少 1h左右。 结论 以 2 0ml/min的滴速 ,用相当于失血量 15 %的 75g/L氯化钠溶液复苏失血性休克效果最佳。 | Cai Xiujun MOU Yiping HUANG Diyu 蔡秀军 牟一平 黄迪宇 彭淑牖 | 2001 | 中华创伤杂志2001，17，2： | 19 |
| 5 | Cost Distortions and Structural Imbalances in China显示文摘这篇论文试图解释中国的基本原因种不平衡问题。经济数据证实关键结构的不平衡问题例如 overinvestment,大当前的帐户剩余, GDP 的低消费份额和收入不平等,都在过去几年败坏了,尽管有改正这些问题的连续政策努力。我们主张关键决定因素是镇压因素费用,它为劳动,资本,土地,资源和环境与重重地弄歪的市场被联系。这些象为制片人,投资者和出口商的含蓄的津贴一样。他们增加生长并且同时,提起投资和出口。以前的政策努力更集中了于行政措施,它一直不是持续的。因此,不平衡问题的一个更基本的答案躺在为生产因素完成面向市场的改革并且允许自由市场决定劳动,资本,土地和资源的价格。 | Yiping Huang Bijun Wang | 2010 | China & World Economy2010，18，4： | 16 |
| 6 | Improving Plant Genome Editing with High-Fidelity xCas9 and Non-canonical PAM-Targeting Cas9-NG显示文摘Two recently engineered SpCas9 variants, namely xCas9 and Cas9-NG, show promising potential in improving targeting specificity and broadening the targeting range. In this study, we evaluated these Cas9 variants in the model and crop plant, rice. We first tested xCas9-3.7, the most effective xCas9 variant in mammalian cells, for targeted mutagenesis at 16 possible NGN PAM (protospacer adjacent motif) combinations in duplicates. xCas9 exhibited nearly equivalent editing efficiency to wild-type Cas9 (Cas9-WT) at most canonical NGG PAM sites tested, whereas it showed limited activity at non-canonical NGH (H = A, C, T) PAM sites. High editing efficiency of xCas9 at NGG PAMs was further demonstrated with C to T base editing by both rAPOBECI and PmCDAI cytidine deaminases. With mismatched sgRNAs, we found that xCas9 had improved targeting specificity over the Cas9-WT. Furthermore, we tested two Cas9-NG variants, Cas9-NGv1 and Cas9-NG, for targeting NGN PAMs. Both Cas9-NG variants showed higher editing efficiency at most non-canonical NG PAM sites tested, and enabled much more efficient editing than xCas9 at AT-rich PAM sites such as GAT, GAA, and CAA. Nevertheless, we found that Cas9-NG variants showed significant reduced activity at the canonical NGG PAM sites. In stable transgenic rice lines, we demonstrated that Cas9-NG had much higher editing efficiency than Cas9-NGv1 and xCas9 at NG PAM sites. To expand the base-editing scope, we developed an efficient C to T base-editing system by making fusion of Cas9-NG nickase (D10A version), PmCDAI, and UGI. Taken together, our work benchmarked xCas9 as a high-fidelity nuclease for targeting canonical NGG PAMs and Cas9-NG as a preferred variant for targeting relaxed PAMs for plant genome editing. | Zhaohui Zhong Simon Sretenovic Qiurong Ren Lijia Yang Yu Bao Caiyan Qi Mingzhu Yuan Yao He Shishi Liu Xiaopei Liu Jiaheng Wang Lan Huang Yan Wang Dibin Baby David Wang Tao Zhang Yiping Qi Yong Zhang | 2019 | Molecular Plant2019，12，7： | 13 |
| 7 | The Late Carboniferous–Early Permian Ocean-Continent Transition in the West Junggar,Central Asian Orogenic Belt: Constraints from Columnar Jointed Rhyolite显示文摘The West Junggar of the western Central Asian Orogenic Belt is one of the typical regions in the term of ocean subduction, contraction and continental growth in the Late Paleozoic. However, it is still controversial on the exact time of ocean-continent transition so far. This study investigates rhyolites with columnar joint in the West Junggar for the first time.Based on zircon U-Pb dating, we determined that the ages of the newly-discovered rhyolites are between 303.6 and 294.5 Ma, belonging to Late Carboniferous–Early Permian, which is the oldest rhyolite with columnar joint preserved in the world at present. Geochemical results show that the characteristics of the major element compositions include a high content of SiO_2(75.78–79.20 wt%) and a moderate content of Al_2O_3(12.21–13.19 wt%). The total alkali content(K_2O +Na_2O) is 6.14–8.05 wt%, among which K_2O is 2.09–4.72 wt% and the rate of K_2O/Na_2O is 0.38–3.05. Over-based minerals such as Ne, Lc, and Ac do not appear. The contents of TiO_2(0.09–0.24 wt%), CaO(0.15–0.99 wt%) and MgO(0.06–0.18 wt%) are low. A/CNK=0.91–1.68, A/NK=1.06–1.76, and as such, these are associated with the quasi-aluminum-weak peraluminous high potassium calc-alkaline and some calc-alkaline magma series. These rhyolites show a significant negative Eu anomaly with relative enrichment of LREE and LILE(Rb, Ba, Th, U, K) and depletion of Sr, HREE and HFSE(Nb, Ta, Ti, P). These rhyolites also have the characteristics of an A2-type granite, similar to the Miaoergou batholith,which indicates they both were affected by post-orogenic extension. Combining petrological, zircon U-Pb dating and geochemical characteristics of the rhyolites, we conclude that the specific time of ocean-continent transition of the West Junggar is the Late Carboniferous–Early Permian. | XU Shenglin CHEN Xuanhua LI Tingdong SHI Jianjie DING Weicui LI Bing HUANG Penghui ZHANG Yiping ZHANG Yaoyao MA Feizhou | 2019 | Acta Geologica Sinica(English Edition)2019，93，2： | 9 |
| 8 | Heterogeneous parallel computing accelerated iterative subpixel digital image correlation显示文摘Parallel computing techniques have been introduced into digital image correlation(DIC) in recent years and leads to a surge in computation speed. The graphics processing unit(GPU)-based parallel computing demonstrated a surprising effect on accelerating the iterative subpixel DIC, compared with CPU-based parallel computing. In this paper, the performances of the two kinds of parallel computing techniques are compared for the previously proposed path-independent DIC method, in which the initial guess for the inverse compositional Gauss-Newton(IC-GN) algorithm at each point of interest(POI) is estimated through the fast Fourier transform-based cross-correlation(FFT-CC) algorithm. Based on the performance evaluation, a heterogeneous parallel computing(HPC) model is proposed with hybrid mode of parallelisms in order to combine the computing power of GPU and multicore CPU. A scheme of trial computation test is developed to optimize the configuration of the HPC model on a specific computer. The proposed HPC model shows excellent performance on a middle-end desktop computer for real-time subpixel DIC with high resolution of more than 10000 POIs per frame. | HUANG JianWen ZHANG LingQi JIANG ZhenYu DONG ShouBin CHEN Wei LIU YiPing LIU ZeJia ZHOU LiCheng TANG LiQun | 2018 | Science China(Technological Sciences)2018，61，1： | 9 |
| 9 | Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study显示文摘 | Caicun Zhou Yi-Long Wu Gongyan Chen Jifeng Feng Xiao-Qing Liu Changli Wang Shucai Zhang Jie Wang Songwen Zhou Shengxiang Ren Shun Lu Li Zhang Chengping Hu Chunhong Hu Yi Luo Lei Chen Ming Ye Jianan Huang Xiuyi Zhi Yiping Zhang Qingyu Xiu Jun Ma Li Zhang C | 2011 | Lancet Oncology2011，，8： | 7 |
| 10 | Enhanced antibacterial behavior of a novel Cu-bearing high-entropy alloy显示文摘Contact infection of bacteria and viruses has been a critical threat to human health. The worldwideoutbreak of COVID-19 put forward urgent requirements for the research and development of the selfantibacterial materials, especially the antibacterial alloys. Based on the concept of high-entropy alloys, thepresent work designed and prepared a novel Co_(0.4)FeCr_(0.9)Cu_(0.3) antibacterial high-entropy alloy with superior antibacterial properties without intricate or rigorous annealing processes, which outperform the antibacterial stainless steels. The antibacterial tests presented a 99.97% antibacterial rate against Escherichiacoli and a 99.96% antibacterial rate against Staphylococcus aureus after 24 h. In contrast, the classic antibacterial copper-bearing stainless steel only performed the 71.50% and 80.84% antibacterial rate, respectively. The results of the reactive oxygen species analysis indicated that the copper ion release and theimmediate contact with copper-rich phase had a synergistic effect in enhancing antibacterial properties.Moreover, this alloy exhibited excellent corrosion resistance when compared with the classic antibacterialstainless steels, and the compression test indicated the yield strength of the alloy was 1015 MPa. Thesefindings generate fresh insights into guiding the designs of structure-function-integrated antibacterial alloys. | Guangyu Ren Lili Huang Kunling Hu Tianxin Li Yiping Lu Dongxu Qiao Haitao Zhang Dake Xu Tongmin Wang Tingju Li Peter K.Liaw | 2022 | Journal of Materials Science & Technology2022，，22： | 6 |
| 11 | Recent advances of pharmaceutical crystallization theories显示文摘As a technology of separation and purification,crystallization plays a vital role in diverse industries such as inorganic salt,pharmaceutical,and food industries,which has a huge impact on purity,crystal polymorph,crystal morphology,and particle size distribution of final products.In the past few decades,with the rapid advancement of experimental approaches and molecular simulation methods,considerable advances in the interpretation of crystallization mechanisms have been obtained,promoting the investigation and understanding of crystallization theories greatly.In this review,the advances of pharmaceutical crystallization theories in recent years from the perspectives of nucleation and crystal growth are summarized and discussed.Two thermodynamic models that are helpful in the study of the crystallization mechanisms will be introduced.In this section,the perturbed-chain statistical associating fluid theory(PC-SAFT)and a chemical-potential-gradient model will be introduced,which have been successfully applied in pharmaceutical solubility prediction,the research of dissolution mechanism as well as dissolution kinetics analysis.These two models are expected to be applied to the study of pharmaceutical crystallization process and mechanism.Furthermore,molecular simulation based on the interaction between particles can provide structural information,thermodynamics,and dynamics properties of complex systems at the molecular level,like intermolecular interaction and surface adsorption energies.Application and some shortcomings of molecular simulation,especially molecular dynamics simulation,in the field of pharmaceutical crystallization will be expounded. | Jingyun Weng Yiping Huang Dule Hao Yuanhui Ji | 2020 | Chinese Journal of Chemical Engineering2020，28，4： | 5 |
| 12 | Evaluation of endocrine disruption and dioxin-like effects of organic extracts from sewage sludge in autumn in Beijing, China显示文摘污水污泥的有效处理和利用上的学习最近是在中国种兴趣的目标。然而,潜在的风险与有毒的 organics,重金属和病原的微生物由于它的污染与污泥的使用被联系。在这研究,一个屏蔽评价在在北京从 17 不同污水处理植物收集的污水污泥样品上被进行,基于批在 vitro 生物鉴定,包括一套 recombinant 基因酵母为内分泌的混乱的试金,并且用为芳基烃受体( Ah-R )的 H4IIE 房间的 ethoxy resorufin-O-deethylase (侵蚀)试金论战的活动。我们的结果建议了那雌激素受体的中等层次论战的活动(0.9 ng E2 愠映杯吗? | Cao LIU Yiping XU Mei MA Bingbin HUANG Jingdong WU Qingyi MENG Zijian WANG Robert Alan GEARHEART | 2014 | Frontiers of Environmental Science & Engineering2014，8，3： | 4 |
| 13 | Completing China's Interest Rate Liberalization显示文摘 | Yuyan Tan Yang Ji Yiping Huang | 2016 | China & World Economy2016，24，2： | 4 |
| 14 | High-order mode lasing in all-FMF laser cavities显示文摘We experimentally demonstrate two kinds of all few-mode fiber(FMF) ring lasers with high-order mode(HOM)oscillation in the laser cavity. One kind is a switchable-wavelength all-FMF HOM laser with an output of tunable optical vortex beams(OVBs); the other is a Q-switched all-FMF HOM laser with an output of pulsed cylindrical vector beams(CVBs). The lasers are composed of all-FMF components and few-mode erbium-doped fiber. A Sagnac interferometer made of a 3 dB FMF coupler functions as the wavelength selector, and switchable multiwavelength tunable OVBs are experimentally realized. Carbon nanotube-based saturable absorbers and the nonlinear polarization rotation technique are used to achieve Q-switched CVB lasers. This is the first report, to our knowledge, on the generation of switchable-wavelength and Q-switched HOM beams in all-FMF laser cavities. | TENG WANG AO YANG FAN SHI YIPING HUANG JIANXIANG WEN XIANGLONG ZENG | 2019 | Photonics Research2019，7，1： | 4 |
| 15 | Liquid modified photonic crystal fiber for simultaneous temperature and strain measurement显示文摘A liquid modified photonic crystal fiber(PCF)integrated with an embedded directional coupler and multi-mode interferometer is fabricated by infiltrating three adjacent air holes of the innermost layer with standard 1.48 refractive index liquids.The refractive index of the filled liquid is higher than that of background silica,which can not only support the transmitting rod modes but also the'liquid modified core'modes propagating between the PCF core and the liquid rods.Hence,the light propagating in the liquid modified core can be efficiently coupled into the satellite waveguides under the phase-matching conditions,resulting in a dramatic decrease of the resonant wavelength intensity.Furthermore,there is a multi-mode interference produced by modified core modes and rod modes.Such a compact(~0.91 cm)device integrated with an embedded coupler and interferometer is demonstrated for high-sensitivity simultaneous temperature(~14.72 nm∕℃)and strain(~13.01 pm∕με)measurement. | CHUPAO LIN YING WANG YIJIAN HUANG CHANGRUI LIAO ZHIYONG BAI MAOXIANG HOU ZHENGYONG LI YIPING WANG | 2017 | Photonics Research2017，5，2： | 3 |
| 16 | 乳腺癌患者的心理状况及相关因素分析(英文)显示文摘Sufferers of breast cancer are often plagued by various psychological problems. Mastectomy, which has a serious influence on the female sex characteristics, can bring about especially serious psychological problems. These problems affect not only the patients’ quality of life but also the beginning, development, and end of the disease. This paper reviewed the relationships between the patients’ personal factors, the disease itself, treatment factors, and other socio-psychological factors and psychological conditions so as to provide new ideas for the psychological intervention on breast cancer patients, comprehensive clinical diagnosis and treatment, and prevention and cure. | Guilin Huang Yiping Wu Guiqing Zhang Pinghua Zhang Jie Gao | 2010 | The Chinese-German Journal of Clinical Oncology2010，9，1： | 3 |
| 17 | B7-DC (PD-L2) costimulation of CD4^(+) T-helper 1 response via RGMb显示文摘The role of B7-DC in T-cell responses remains controversial because both coinhibitory and costimulatory functions have been reported in various experimental systems in vitro and in vivo.In addition to interacting with the coinhibitory receptor PD-1,B7-DC has also been shown to bind repulsive guidance molecule b(RGMb).The functional consequences of the B7-DC/RGMb interaction,however,remain unclear.More than a decade ago,we reported that replacement of a murine B7-DC mutant lysine with serine(K113S)at positive 113 resulted in a loss of binding capacity to PD-1.Nevertheless,K113S remained costimulatory for T cells in vitro,implicating a dual functionality for B7-DC in T-cell responses.Here we show that recombinant K113S protein interacts with RGMb with a similar affinity to wild-type B7-DC.More importantly,K113S costimulates CD4^(+)T-cell responses via RGMb and promotes Th1 polarization.RGMb is expressed on the surface of naive mouse T cells,macrophages,neutrophils and dendritic cells.Finally,K113S/RGMb costimulation suppresses Th2-mediated asthma and ameliorates small airway inflammation and lung pathology in an experimental mouse model.Our findings indicate that RGMb is a costimulatory receptor for B7-DC.These findings from the K113S variant provide not only a possible explanation for the B7-DC-triggered contradictory effects on T-cell responses,but also a novel approach to investigate the B7-DC/PD-1/RGMb axis.Recombinant K113S or its derivatives could potentially be developed as an agonist for RGMb to costimulate the Th1 response without triggering PD-1-mediated T-cell inhibition. | Xinxin Nie Wenni Chen Ying Zhu Baozhu Huang Weiwei Yu Zhanshuai Wu Sizheng Guo Yiping Zhu Liqun Luo Shengdian Wang Lieping Chen | 2018 | Cellular & Molecular Immunology2018，15，10： | 3 |
| 18 | Hydrodynamics and bubble behaviour in a three-phase two-stage internal loop airlift reactor显示文摘Local hydrodynamics of a gas–liquid–solid system,such as bubble circulation regime,gas holdup,liquid velocity and axial profile of solid concentration,are studied in a two-stage internal loop airlift reactor.Empirical correlations for gas holdup and liquid velocity are proposed to ease the reactor design and scale-up.Different bubble circulation regimes were displayed in the first(lower) and second(upper) stages.Increasing superficial gas velocity and solid loading can promote regime transition of the second stage,and the gas holdup of the second stage is higher than that of the lower stage.In addition,the effects of solid loading on bubble behaviour are experimentally investigated for each stage.It is found that bubble size in the downcomer decreases with the presence of solid particles,and bubble size distribution widens under higher superficial gas velocity and lower solid loading. | Dan Li Kai Guo Jingnan Li Yiping Huang Junchao Zhou Hui Liu Chunjiang Liu | 2018 | Chinese Journal of Chemical Engineering2018，26，6： | 3 |
| 19 | MiR-145, miR-133a and miR-133b inhibit proliferation, migration, invasion and cell cycle progression via targeting transcription factor Sp1 in gastric cancer显示文摘 | Tianzhu Qiu Xin Zhou Jian Wang Yiping Du Jun Xu Zebo Huang Wei Zhu Yongqian Shu Ping Liu | 2014 | FEBS Letters2014，，7： | 3 |
| 20 | Senp2 regulates adipose lipid storage by de-SUMOylation of Setdbl显示文摘 | Quan Zheng Ying Cao Yalan Chen Jiqiu Wang Qiuju Fan Xian Huang Yiping Wang Tianshi Wang Xiuzhi Wang Jiao Ma Jinke Cheng | 2018 | Journal of Molecular Cell Biology2018，10，3： | 2 |
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