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| 1 | Clinical features and treatment status of hemifacial spasm in China显示文摘 | Wang Lin Hu Xingyue Dong Hongjuan Wang Wenzhao Huang Yue Jin Lingjing Luo Yumin Zhang Weixi Lian Yajun Liang Zhanhua Shang Huifang Feng Yabo wu Yiwen Chen Jun Luo Weifeng Wan Xinhua | 2014 | Chinese Medical Journal2014，，5： | 20 |
| 2 | The Hippo signaling pathway in liver regeneration and tumorigenesis显示文摘表明小径的河马是在肝尺寸控制和 tumorigenesis 起关键作用的一个 evolutionarily 保存的发信号的模块。河马小径由在的核心 kinase 串联组成哺乳动物的象 Ste20 一样 kinases (Mst1/2,果蝇河马的 orthologs ) 并且他们的余因子萨尔瓦多(Sav1 ) 形成建筑群到 phosphorylate 并且激活大肿瘤 suppressor (Lats1/2 ) 。Lats1/2 kinases 接着 phosphorylate 并且与 PDZ 有约束力的主题(TAZ ) 禁止抄写激活剂,联系是的蛋白质(笨蛋) 和 transcriptional 激活剂,河马小径的二个主要下游的受动器。河马小径部件的损失导致异常肝肿大和 tumorigenesis,笨蛋在协调房间增长和 apoptosis 的规定并且起一个必要作用。这评论总结在肝新生和 tumorigenesis 发信号的河马的规定的当前的调查结果,集中河马小径的肿瘤 suppressor 部件的损失怎么导致肝癌症并且讨论调整它在肝 tumorigenesis 的下游的受动器笨蛋的表示和激活的分子的机制。 | Lixin Hong Yabo Cai Mingting Jiang Dawang Zhou Lanfen Chen | 2015 | Acta Biochimica et Biophysica Sinica2015，47，1： | 12 |
| 3 | Cationic content effects of biodegradable amphoteric chitosan-based flocculants on the flocculation properties显示文摘A series of biodegradable amphoteric chitosan-based flocculants(3-chloro-2-hydroxypropyl trimethyl ammonium chloride(CTA) modified carboxymethyl chitosan,denoted as CMC-CTA) with different substitution degrees of CTA were prepared successfully.The content of carboxymethyl groups in each CMC-CTA sample was kept almost constant.The solubility of the various flocculants showed that,higher cationic content of flocculants caused a better solubility.The flocculation experiments using kaolin suspension as synthetic water at the laboratory scale indicated that the substitution degree of CTA was one of the key factors for the flocculation properties.With the increase of cationic content,the flocculants were demonstrated better flocculation performance and lower dosage requirement.Flocculation kinetics model of particles collisions combining zeta potential and turbidity measurements was employed to investigate the effects of the cationic content of the flocculants on the flocculation properties from the viewpoint of flocculation mechanism in detail.Furthermore,flocculation performance using raw water from Zhenjiang part of Yangtze River at the pilot scale showed the similar effects to those at the laboratory scale. | Zhen Yang Yabo Shang Xin Huang Yichun Chen Yaobo Lu Aimin Chen Yuxiang Jiang Wei Gu Xiaozhi Qian Hu Yang Rongshi Cheng | 2012 | Journal of Environmental Sciences2012，24，8： | 8 |
| 4 | Vegfa signaling regulates diverse artery/vein formation in vertebrate vasculatures显示文摘Vascular endothelial growth factor A(Vegfa) signaling regulates vascular development during embryogenesis and organ formation.However,the signaling mechanisms that govern the formation of various arteries/veins in various tissues are incompletely understood.In this study,we utilized transcription activator-like effector nuclease(TALEN) to generate zebrafish vegfaa mutants.vegfaa^(-/-) embryos are embryonic lethal,and display a complete loss of the dorsal aorta(DA) and expansion of the cardinal vein.Activation of Vegfa signaling expands the arterial cell population at the expense of venous cells during vasculogenesis of the axial vessels in the trunk.Vegfa signaling regulates endothelial cell(EC) proliferation after arterial-venous specification.Vegfa deficiency and overexpression inhibit the formation of tip cell filopodia and interfere with the pathfinding of intersegmental vessels(ISVs).In the head vasculature,vegfaa^(-/-) causes loss of a pair of mesencephalic veins(MsVs) and central arteries(CtAs),both of which usually dvelop via sprouting angiogenesis.Our results indicate that Vegfa signaling induces the formation of the DA at the expense of the cardinal vein during the trunk vasculogenesis,and that Vegfa is required for the angiogenic formation of MsVs and CtAs in the brain.These findings suggest that Vegfa signaling governs the formation of diverse arteries/veins by distinct cellular mechanisms in vertebrate vasculatures. | Daqing Jin Diqi Zhu Yabo Fang Yiwei Chen Gaihong Yu Weijun Pan Dong Liu Fen Li Tao P.Zhong | 2017 | Journal of Genetics and Genomics2017，44，10： | 6 |
| 5 | Study of ultrahigh-purity copper billets refined by vacuum melting and directional solidification显示文摘The purpose of this paper is to study large-sized copper billets refined with 5N ultrahigh purity after vacuum melting and directional solidifi-cation (VMDS). The precise impurity analysis of copper billets was carried out with a glow discharge mass spectrometer (GDMS). The re-sults demonstrate that the total concentration of twenty-two impurities is decreased by 63.1wt.%-66.5 wt.%. Ag, P, S, Na, Mg, Se, Zn, In and Bi are easy to be removed due to lgPimp - lgPCu > 1.5, and they can be removed effectively under the vacuum condition of 1650-1700 K for 30 min. The electrical conductivity of 5N copper is higher than that of the raw material as the impurity concentrations decrease. The segrega-tion effect in directional solidification can be remarkable when the equilibrium distribution coefficient (k0) value is less than 0.65 due to the strong affinity of Cu for some metallic and non-metallic impurities. | FU Yabo CHEN Jie LIU Ning LU Yiping LI Tingju YIN Guomao | 2011 | Rare Metals2011，30，3： | 6 |
| 6 | Effects of L-3-n-butylphthalide on caspase-3 and nuclear factor kappa-B expression in primary basal forebrain and hippocampal cultures after beta-amyloid peptide 1-42 treatment显示文摘BACKGROUND:L-3-n-butylphthalide(L-NBP) can inhibit phosphorylation of tau protein and reduce the neurotoxicity of beta-amyloid peptide 1-42(Aβ_(1-42)). OBJECTIVE:To observe the neuroprotective effects of L-NBP on caspase-3 and nuclear factor kappa-B(NF-κB) expression in a rat model of Alzheimer's disease. DESIGN,TIME AND SETTING:A cell experiment was performed at the Central Laboratory of Provincial Hospital affiliated to Shandong University between January 2008 and August 2008. MATERIALS:L-NBP(purity>98%) was provided by Shijiazhuang Pharma Group NBP Pharmaceutical Company Limited.Aβ_(1-42),3-[4,5-dimethylthiazolo-2]-2,5 iphenyltetrazolium bromide(MTT),and rabbit anti-Caspase-3 polyclonal antibody were provided by Cell Signaling, USA;goat anti-choactase and rabbit anti-NF-κB antibodies were provided by Santa Cruz,USA. METHODS:Primary cultures were generated from rat basal forebrain and hippocampal neurons at 17 or 19 days of gestation.The cells were assigned into five groups:the control group,the Aβ_(1-42) group(2μmol/ L),the Aβ_(1-42) + 0.1μmol/L L-NBP group,the Aβ_(1-42)+ 1μmol/L L-NBP group,and the Aβ_(1-42)+ 10μmol/L L-NBP group.The neurons were treated with Aβ_(1-42)(2μmol/L) alone or in combination with L-NBP(0.1,1,10μmol/L) for 48 hours.Cells in the control group were incubated in PBS. MAIN OUTCOME MEASURES:Morphologic changes were evaluated using inverted microscopy, viability using the MTT method,and the changes in caspase-3 and NF-κB expression using Western blot. RESULTS:Induction with Aβ_(1-42) for 48 hours caused cell death and soma atrophy,and increased caspase-3 and NF-κB expression(P<0.05).L-NBP blocked these changes in cell morphology, decreased caspase-3 and NF-κB expression(P<0.05),and improved cell viability,especially at the high dose(P<0.05). CONCLUSION:Aβ_(1-42) is toxic to basal forebrain and hippocampal primary neurons;L-NBP protects against this toxicity and inhibits the induction of caspase-3 and NF-κB expression. | Ruixia Wang Yong Zhang Liangliang Jiang Guozhao Ma Qingxi Fu Jialong Li Peng Yan Lunqian Shen Yabo Feng Chunxia Li Zaiying Pang Yuanxiao Cui Chunfu Chen Yifeng Du Zhaokong Liu | 2009 | Neural Regeneration Research2009，4，4： | 3 |
| 7 | Mn atomic layers under inert covers of graphene and hexagonal boron nitride prepared on Rh(111)显示文摘进 graphene 和它的支持的底层的接口的金属原子的置闰为削弱联合并且构造金属的接口的缘故成为了一个吸引人的话题在惰性的封面下面的原子层。然而,这新奇行为很少在类似的六角形的硼氮化物(h-BN ) 上被报导了在金属底层上综合了。这里,我们描述 Mn 置闰的比较研究进 graphene/Rh (111 ) 和 h-BN/Rh (111 ) 的接口,由使用解决 atomically 的扫描通道显微镜学(STM ) 和密度功能的理论(DFT ) 计算。置闰被退火执行同样扔的 Mn 簇,和进 h-BN/Rh (111 ) 的 Mn 置闰的开始的温度被发现是 80 瑩 ?? 数歡瀠睯牥搠湥楳祴漠 ??? ″坭洯吗? | Yu Zhang Yanfeng Zhang Donglin Ma Qingqing Ji Wei Fang Jianping Shi Teng Gao Mengxi Liu Yabo Gao Yubin Chen Limei Xu Zhongfan Liu | 2013 | Nano Research2013，6，12： | 2 |
| 8 | High-dimensional immune profiling by mass cytometry revealed immunosuppression and dysfunction of immunity in COVID-19 patients显示文摘The outbreak of coronavirus disease 2019(COVID-19)caused by the new virus SARS-CoV-2 has been announced as a public health emergency of international concern.1–3 The clinical features of patients with COVID-19 range from common fever and cough to other rare symptoms,such as diarrhea and nausea.This disease can progress quickly,and 2–3%of patients die within a short time,which is generally due to multiple organ failure.4–7 Clinically,COVID-19 patients are classified into mild,moderate,severe,and critical cases.5–7 The immune response against SARS-CoV-2 is probably linked to the severity of disease.Recently,Zheng et al.8 showed that elevated levels of T-cell exhaustion and reduced functional diversity of T cells in peripheral blood may predict severe progression in COVID-19 patients;however,a more comprehensive understanding of the pathology of SARS-CoV-2 infection remains to be delineated.Here,we profiled immune cellular components using mass cytometry(CyTOF)to analyze the peripheral blood mononuclear cells(PBMCs)from patients with differences in disease progression by comparing with the PBMCs from healthy donors(HDs). | Wenjing Wang Bin Su Lijun Pang Luxin Qiao Yingmei Feng Yabo Ouyang Xianghua Guo Hongbo Shi Feili Wei Xiaogang Su Jiming Yin Ronghua Jin Dexi Chen | 2020 | Cellular & Molecular Immunology2020，17，6： | 2 |
| 9 | Fiber Migration and Twist Radial Distribution in Rotor Spun Yarns 显示文摘 | Zhang Hongwei Chen Dongsheng Wan Yabo | 2003 | Textile Research Journal2003，73，11： | 1 |
| 10 | Fiber Migration and Twist Radial Dislrihution in Rotor Spunyarns显示文摘 | Zhang Hongwei Chen I)ongsheng Wan Yabo | 2003 | Textile Research Journal2003，5，11： | 1 |
| 11 | An Internetenabled image-and model-based Virtual Machining System显示文摘 | Luo Yabo Ong S K Chen Dingfang | 2002 | International Journal of Production Research2002，40，10： | 1 |
| 12 | Study in Realizing Virtual Reality by Software显示文摘 | Chen Dingfang | 1999 | Proceeding of Second International Conference on CAID&CD''991999，，： | 1 |
| 13 | An anionic In(Ⅲ)-based metal-organic framework with Lewis basic sites for the selective adsorption and separation of organic cationic dyes显示文摘In this paper, a new anionic metal-organic framework, [In(PBPTTBA)][(CH_3)_2 NH_2](BUT-29) has been synthesized through the reaction of tetratopic acid ligand with double Lewis pyridine sites, 4,4',4'',4'''-(4,4'-(1,4-phenylene)bis(pyridine-6,4,2-triyl)) tetrabenzoic acid(H_4 PBPTTBA) and In(NO_3)_2·5H_2O and fully characterized by single-crystal X-ray diffraction(SXRD), powder X-ray diffraction(PXRD),thermogravimetric analysis(TGA), infrared spectroscopy(IR), and elemental analysis(EA). BUT-29 can be used as an efficient adsorbent for the selective removal of organic cationic dyes in N,N0-dimethylformamide(DMF) solution. The adsorption capacities of BUT-29 toward methylene blue and crystal violet at 298 K can reach 1119 mg/g and 832 mg/g, respectively. Moreover, the adsorbed dyes can be released in the DMF solution of LiNO_3 gradually. | Qi Yang Bin Wang Ya Chen Yabo Xie Jianrong Li | 2019 | Chinese Chemical Letters2019，30，1： | 1 |
| 14 | An Internet - enabled image- and model-based virtual machining system显示文摘 | LUO Yabo ONG S K CHEN Dingfang | 2002 | International Journal of Production Research2002，40，10： | 1 |
| 15 | Study on plastic behaviours of CuNi10Fe1Mn alloy tubes under cast-roll process显示文摘 | Yabo Fu Zhiming Yan Tingju Li Ping Chen Yanfeng Cheng Guomao Yin | 2009 | Materials and Design2009，，10： | 1 |
| 16 | Fiber migration and twist radial distribution in rotor spun yarns显示文摘 | ZHANG Hongwei CHEN Dongsheng WAN Yabo | 2003 | Textile Research Journal2003，，11： | 1 |
| 17 | Synthesis of anatase titania-carbon nanotubes nanocomposites with enhanced photocatalytic activity through a nanocoating-hydrothermal process显示文摘 | Qun Wang Dong Yang Daimei Chen Yabo Wang Zhongyi Jiang | 2007 | Journal of Nanoparticle Research2007，，6： | 1 |
| 18 | 查看详情显示文摘 | Huo Chunqing Sang Lijun Chen Qiang Yue Lei Fu Yabo | | 0，，04： | 1 |
| 19 | Seed-aided green synthesis of metal-organic frameworks in water显示文摘Green synthesis of metal-organic frameworks(MOFs)in water with alleviated environmental influence and reduced cost is an essential step to transfer laboratory MOFs research to industrial application.Switching from the commonly used organic solvents to pure water encounters challenges of the poor solubility of organic linkers,slow reaction kinetics,and the formation of polymorphic products.So far,a universal MOFs synthetic strategy in water system has yet to be developed.This study reports the seed-aided synthesis of eleven MOFs with diverse compositions and structures while pure water serving as solvent.The corresponding reaction temperature and time of using this new strategy were reduced compared with original synthetic approaches,while the products maintain porous structure and high crystallinity.The success of this strategy relies on the addition of parent MOFs as seeds which could promote crystallization process by skipping the time-consuming induction period and avoiding the formation of polymorphic impurities. | Hao-Tian An Xin Zhang Chen Dong Mu-Yao Lu Rui Li Yabo Xie Lin-Hua Xie Jian-Rong Li | 2023 | Green Chemical Engineering2023，4，1： | 0 |
| 20 | New method for estimating strike and dip based on structural expansion orientation for 3D geological modeling显示文摘Strike and dip are essential to the description of geological features and therefore play important roles in 3D geological modeling.Unevenly and sparsely measured orientations from geological field mapping pose problems for the geological modeling,especially for covered and deep areas.This study developed a new method for estimating strike and dip based on structural expansion orientation,which can be automatically extracted from both geological and geophysical maps or profiles.Specifically,strike and dip can be estimated by minimizing an objective function composed of the included angle between the strike and dip and the leave-one-out cross-validation strike and dip.We used angle parameterization to reduce dimensionality and proposed a quasi-gradient descent(QGD)method to rapidly obtain a near-optimal solution,improving the time-efficiency and accuracy of objective function optimization with the particle swarm method.A synthetic basin fold model was subsequently used to test the proposed method,and the results showed that the strike and dip estimates were close to the true values.Finally,the proposed method was applied to a real fold structure largely covered by Cainozoic sediments in Australia.The strikes and dips estimated by the proposed method conformed to the actual geological structures more than those of the vector interpolation method did.As expected,the results of 3D geological implicit interface modeling and the strike and dip vector field were much improved by the addition of estimated strikes and dips. | Yabo ZHAO Weihua HUA Guoxiong CHEN Dong LIANG Zhipeng LIU Xiuguo LIU | 2021 | Frontiers of Earth Science2021，15，3： | 0 |
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