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| 1 | Heat and power load dispatching considering energy storage of district heating system and electric boilers显示文摘As one of promising clean and low-emission energy, wind power is being rapidly developed in China.However, it faces serious problem of wind curtailment,particularly in northeast China, where combined heat and power(CHP) units cover a large proportion of the district heat supply. Due to the inherent strong coupling between the power and the heat load, the operational flexibility of CHP units is severely restricted in winter to meet the heat supply demand, which imparts considerable stress on the wind power connection to the grid. To promote the integration of wind power and enhance the flexibility of CHP units, this paper presented a method of heat and power load dispatching by exploring the energy storage ability of electric heating boilers and district heating systems. The optimization results indicate that the proposed method can integrate additional wind power into the grid and reduce the coal consumption of CHP units over the optimized period. Furthermore, the thermal inertia of a district heating system is found to contribute more to the reduction of coal consumption, whereas the electric heating boilers contribute to lower wind curtailment. | Xianzheng HUANG Zhaofeng XU Yong SUN Yali XUE Zhe WANG Zhijun LIU Zhenyuan LI Weidou NI | 2018 | Journal of Modern Power Systems and Clean Energy2018，6，5： | 20 |
| 2 | Adaptive recurrent-functional-link-network control for hypersonic vehicles with atmospheric disturbances显示文摘The controller design for a near-space hypersonic vehicle (NHV) is challenging due to its plant uncertainties and sensitivity to atmospheric disturbances such as gusts and turbulence. This paper first derives 12 states equations of NHVs subjected to variable wind field, and presents a novel recurrent neural network (RNN) control method for restraining atmospheric disturbances. The method devises a new B-spline recurrent functional link network (BRFLN) and combines it with the nonlinear generalized predictive control (NGPC) algorithm. Moreover, the proportional-derivative (PD) correction BRFLN is proposed to approximate atmo- spheric disturbances in flight. The weights of BRFLN are online tuned by the adaptive law based on Lyapunov stability theorem. Finally, simulation results show a satisfactory performance for the attitude tracking of the NHV in the mesosphere, and also illustrate the controller's robustness to wind turbulence. | DU YanLi WU QingXian JIANG ChangSheng XUE YaLi | 2011 | Science China(Information Sciences)2011，54，3： | 8 |
| 3 | Generalized Predictive Control for Superheated Steam Temperature Regulation in a Supercritical Coal-fired Power Plant显示文摘The design and implementation of a Generalized Predictive Control(GPC)strategy for the superheated steam temperature regulation in a supercritical(SC)coal-fired power plant is presented.A Controlled Auto-Regressive MovingAverage(CARMA)model of the plant is derived from using the experimental data to approximately predict the plant’s future behavior.This model is required by the GPC algorithm to calculate the future control inputs.A new GPC controller is designed and its performance is tested through extensive simulation studies.Compared with the performance of the plant using a conventional PID controller,the steam temperature controlled by the GPC controller is found to be more stable.The stable steam temperature leads to more efficient plant operation and energy saving,as demonstrated by the simulation results.Plant performance improvement is also tested while the plant experiences the load demand changes and disturbances resulting from the malfunctioning of coal mills. | Mihai Draganescu Shen Guo Jacek Wojcik Jihong Wang Xiangjie Liu Guolian Hou Yali Xue Qirui Gao | 2015 | CSEE Journal of Power and Energy Systems2015，1，1： | 7 |
| 4 | Trajectory linearization control of an aerospace vehicle based on RBF neural network显示文摘An enhanced trajectory linearization control (TLC) structure based on radial basis function neural network (RBFNN) and its application on an aerospace vehicle (ASV) flight control system are presensted.The influence of unknown disturbances and uncertainties is reduced by RBFNN thanks to its approaching ability,and a robustifying item is used to overcome the approximate error of RBFNN.The parameters adaptive adjusting laws are designed on the Lyapunov theory.The uniform ultimate boundedness of all signals of the composite closed-loop system is proved based on Lyapunov theory.Finally,the flight control system of an ASV is designed based on the proposed method.Simulation results demonstrate the effectiveness and robustness of the designed approach. | Xue Yali Jiang Changsheng | 2008 | Journal of Systems Engineering and Electronics2008，19，4： | 6 |
| 5 | Selective Aberrant Functional–Structural Coupling of Multiscale Brain Networks in Subcortical Vascular Mild Cognitive Impairment显示文摘Subcortical vascular mild cognitive impairment(svMCI)is a common prodromal stage of vascular dementia.Although mounting evidence has suggested abnormalities in several single brain network metrics,few studies have explored the consistency between functional and structural connectivity networks in svMCI.Here,we constructed such networks using resting-state f MRI for functional connectivity and diffusion tensor imaging for structural connectivity in 30 patients with svMCI and 30 normal controls.The functional networks were then parcellated into topological modules,corresponding to several well-defined functional domains.The coupling between the functional and structural networks was finally estimated and compared at the multiscale network level(whole brain and modular level).We found no significant intergroup differences in the functional–structural coupling within the whole brain;however,there was significantly increased functional–structural coupling within the dorsal attention module and decreased functional–structural coupling within the ventral attention module in the svMCI group.In addition,the svMCI patients demonstrated decreased intramodular connectivity strength in the visual,somatomotor,and dorsal attention modules as well as decreased intermodular connectivity strength between several modules in the functional network,mainly linking the visual,somatomotor,dorsal attention,ventral attention,and frontoparietal control modules.There was no significant correlation between the altered module-level functional–structural coupling and cognitive performance in patients with svMCI.These findings demonstrate for the first time that svMCI is reflected in a selective aberrant topological organization in multiscale brain networks and may improve our understanding of the pathophysiological mechanisms underlying svMCI. | Juanwei Ma Feng Liu Bingbing Yang Kaizhong Xue Pinxiao Wang Jian Zhou Yang Wang Yali Niu Jing Zhang | 2021 | Neuroscience Bulletin2021，37，3： | 4 |
| 6 | Diagnostic value of negative enrichment and immune fluorescence in situ hybridization for intraperitoneal free cancer cells of gastric cancer显示文摘Objective:To explore the intraperitoneal free cancer cell(IFCC)detection value of negative enrichment and immune fluorescence in situ hybridization(NEimFISH)on chromosomes(CEN)8/17.Methods:To verify the reliability of NEimFISH,29 gastric cancer tumors,their adjacent tissues and greater omental tissues were tested.Our study then included 105 gastric cancer patients for IFCC.We defined patients as IFCC-positive if a signal was detected,regardless of the detailed cancer cell numbers.A comparison of clinicopathological features was conducted among IFCC groups.We also compared the diagnosis value and peritoneal recurrence predictive value among different detection methods.The comparison of IFCC number was also conducted among different groups.Results:A cutoff of 2.5 positive cells could distinguish all benign tissue samples and 97%of malignant tissue samples in our study.Compared to intestinal gastric cancer,patients with diffuse gastric cancer tended to have more IFCCs(6 vs.4,P=0.002).The IFCC counts were often higher in the lymphovascular invasion positive group than negative group(3 vs.1,P=0.022).All IFCC samples that were considered positive using conventional cytology were also found to be positive using NEimFISH.When compared to conventional cytology and paraffin pathology,NEimFISH had a higher IFCC positive rate(68.9%)and higher one-year peritoneal recurrence predictive value with area under the curve(AUC)of 0.922.Conclusions:Gastric cancer could be effectively diagnosed by NEimFISH.The IFCC number found using NEimFISH on CEN8/17 is closely associated with Lauren type and vascular invasion of cancer.NEimFISH is a reliable detection modality with a higher positive detection rate,higher one-year peritoneal recurrence predictive value and quantitative features for IFCC of gastric cancer. | Anqiang Wang Zhongwu Li Qian Wang Yali Bai Xin Ji Tao Fu Ke Ji Yanwen Xue Tingxu Han Xiaojiang Wu Ji Zhang Yingjie Yang Guobin Xu Zhaode Bu Jiafu Ji | 2019 | Chinese Journal of Cancer Research2019，31，6： | 3 |
| 7 | Contribution of Temperature Increase to Restrain the Transmission of COVID-19显示文摘The COVID-19 outbreak has already become a global pandemic and containing this rapid worldwide transmission is of great challenge.The impacts of temperature and humidity on the COVID-19 transmission rate are still under discussion.Here,we elucidated these relationships by utilizing two unique scenarios,repeated measurement and natural experiment,using the COVID-19 cases reported from January 23–February 21,2020,in China.The modeling results revealed that higher temperature was most strongly associated with decreased COVID-19 transmission at a lag time of 8 days.Relative humidity(RH)appeared to have only a slight effect.These findings were verified by assessing SARSCoV-2 infectivity under the relevant conditions of temperature(4C–37C)and RH(>40%).We concluded that temperature increase made an important,but not determined,contribution to restrain the COVID19 outbreak in China.It suggests that the emphasis of other effective controlling polices should be strictly implemented to restrain COVID19 transmission in cold seasons. | Mengyuan Ren Rongjuan Pei Bahabaike Jiangtulu Junxi Chen Tao Xue Guofeng Shen Xiaoru Yuan Kexin Li Changxin Lan Zhen Chen Xinwen Chen Yun Wang Xiaoqian Jia Zewu Li Audil Rashid Tippawan Prapamontol Xiuge Zhao Zhaomin Dong Yali Zhang Le Zhang Rongwei Ye Zhiwen Li Wuxiang Guan Bin Wang | 2021 | The Innovation2021，2，1： | 2 |
| 8 | Unimodal productivity-biodiversity relationship along the gradient of multidimensional resources across Chinese grasslands显示文摘Resources can affect plant productivity and biodiversity simultaneously and thus are key drivers of their relationships in addition to plant-plant interactions.However,most previous studies only focused on a single resource while negle cting the nature of resource multidimensionality.Here we integrated four essential resources for plant growth into a single metric of resource diversity(RD)to investigate its effects on the productivity-biodiversity relationship(PBR)across Chinese grasslands.Results showed that habitats differing in RD have different PBRs—positive in low-resource habitats,but neutral in medium-and high-resource ones—while collectively,a weak positive PBR was observe d.However,when excluding direct effects of RD on productivity and biodiversity,the PBR in high-resource habitats became negative,which leads to a unimodal instead of a positive PBR along the RD gradient.By integrating resource effects and changing plant-plant interactions into a unified framework with the RD gradient,our work contributes to uncovering underlying me chanisms for inconsistent PBRs at large scales. | Yanfen Wang Jianqing Du Zhe Pang Yali Liu Kai Xue Yann Hautier Biao Zhang Li Tang Lili Jiang Baoming Ji Xingliang Xu Jing Zhang Ronghai Hu Shutong Zhou Fang Wang Rongxiao Che Di Wang Chaoting Zhou Xiaoyong Cui Nico Eisenhauer Yanbin Hao | 2022 | National Science Review2022，9，12： | 2 |
| 9 | Polymorphism study of seven SNPs at ADH genes in 15 Chinese populations Heieditas显示文摘 | LINLIN M A YALI XUE YAN LIU | 2005 | 142:103-1112005，142，： | 1 |
| 10 | Mesenchymal Stem Cells Promote Epithelial to Mesenchymal Transition and Metastasis in Gastric Cancer Though Paracrine Cues and Close Physical Contact显示文摘 | Zengfu Xue Xiumin Wu Xiong Chen Yali Liu Xin Wang Kaichun Wu Yongzhan Nie Daiming Fan | 2015 | Biochem2015，，4： | 1 |
| 11 | Evenness is important in assessing progress towards sustainable development goals显示文摘Sustainable development goals(SDGs)emphasize a holistic achievement instead of cherry-picking a few.However,no assessment has quantitatively considered the evenness among all 17 goals.Here,we propose a systematic method,which first integrates both the evenness and the overall status of all goals,to distinguish the ideal development pathways from the uneven ones and then revisit the development trajectory in China from 2000 to 2015.Our results suggest that,despite the remarkable progress,a bottleneck has occurred in China since 2013 due to the stagnant developments in some SDGs.However,many far-reaching policies in China have been targeting these deficiencies since then,providing a perspective on how a country approaches sustainable development by promoting evenness among all SDGs.Our results also indicate that regions with the slowest progress are the developed provinces,owing to the persistent uneven status of all goals.Our study demonstrates the importance of adopting evenness in assessing and guiding sustainable development. | Yali Liu Jianqing Du Yanfen Wang Xiaoyong Cui Jichang Dong Yanbin Hao Kai Xue Hongbo Duan Anquan Xia Yi Hu Zhi Dong Bingfang Wu Xinquan Zhao Bojie Fu | 2021 | National Science Review2021，8，8： | 1 |
| 12 | Active disturbance rejection control for the ALSTOM gasifier benchmark problem 显示文摘 | HUANG Chun'e LI Donghai XUE Yali | 2013 | Control Engineering Practice2013，21，4： | 1 |
| 13 | An Exceptional Gene:Evolution of the TSPY Gene Family in Humans and Other Great Apes 显示文摘 | Yali Xue Chris Tyler Smith | 2011 | Genes2011，，2： | 1 |
| 14 | Can Digital Intelligence and Cyber-Physical-Social Systems Achieve Global Food Security and Sustainability?显示文摘Plants sequester carbon through photosynthesis and provide primary productivity for the ecosystem. However, they also simultaneously consume water through transpiration, leading to a carbon-water balance relationship. Agricultural production can be regarded as a form of carbon sequestration behavior.From the perspective of the natural-social-economic complex ecosystem, excessive water usage in food production will aggravate regional water pressure for both domestic and industrial purposes. Hence, achieving a harmonious equilibrium between carbon and water resources during the food production process is a key scientific challenge for ensuring food security and sustainability. Digital intelligence(DI) and cyber-physical-social systems(CPSS) are emerging as the new research paradigms that are causing a substantial shift in the conventional thinking and methodologies across various scientific fields, including ecological science and sustainability studies. This paper outlines our recent efforts in using advanced technologies such as big data, artificial intelligence(AI), digital twins, metaverses, and parallel intelligence to model, analyze, and manage the intricate dynamics and equilibrium among plants, carbon, and water in arid and semiarid ecosystems. It introduces the concept of the carbon-water balance and explores its management at three levels: the individual plant level, the community level, and the natural-social-economic complex ecosystem level. Additionally, we elucidate the significance of agricultural foundation models as fundamental technologies within this context. A case analysis of water usage shows that, given the limited availability of water resources in the context of the carbon-water balance, regional collaboration and optimized allocation have the potential to enhance the utilization efficiency of water resources in the river basin. A suggested approach is to consider the river basin as a unified entity and coordinate the relationship between the upstream, midstream and downstream areas. Furthermore, establishing mechanisms for water resource transfer and trade among different industries can be instrumental in maximizing the benefits derived from water resources.Finally, we envisage a future of agriculture characterized by the integration of digital, robotic and biological farming techniques.This vision aims to incorporate small tasks, big models, and deep intelligence into the regular ecological practices of intelligent agriculture. | Yanfen Wang Mengzhen Kang Yali Liu Juanjuan Li Kai Xue Xiujuan Wang Jianqing Du Yonglin Tian Qinghua Ni Fei-Yue Wang | 2023 | IEEE/CAA Journal of Automatica Sinica2023，10，11： | 1 |
| 15 | Mesenchymal Stem Cells Promote Epithelial to Mesenchymal Transition and Metastasis in Gastric Cancer Though Paracrine Cues and Close Physical Contact显示文摘 | Zengfu Xue Xiumin Wu Xiong Chen Yali Liu Xin Wang Kaichun Wu Yongzhan Nie Daiming Fan | 2015 | J. Cell. Biochem2015，，： | 1 |
| 16 | Male Demography in East Asia:A North–South contrast in human population expansion Times显示文摘 | Yali Xue Tatiana Zerjal Weidong Bao | 2006 | Genetics2006，172，： | 1 |
| 17 | Role of epimorphin in bile duct formation of rat liver epithelial stem‐like cells: Involvement of small G protein RhoA and C/EBPβ显示文摘 | Yali Jia Hailei Yao Junnian Zhou Lin Chen Quan Zeng Hongfeng Yuan Lei Shi Xue Nan Yunfang Wang Wen Yue Xuetao Pei | 2011 | J Cell Physiol2011，，11： | 1 |
| 18 | Male demography in East Asia: a north-south contrast in human population expan- sion times显示文摘 | Yali Xue Tatiana Zerjal Weidong Bao | 2006 | Genetics2006，172，4： | 1 |
| 19 | Engineering heterointerfaces coupled with oxygen vacancies in lanthanum–based hollow microspheres for synergistically enhanced oxygen electrocatalysis显示文摘The development of high–efficiency and low–cost bifunctional oxygen electrocatalysts is critical to enlarge application of zinc–air batteries(ZABs). However, it still remains challenges due to their uncontrollable factor at atomic level during the catalysts preparation, which requires the precise regulation of active sites and structure engineering to accelerate the reaction kinetics for both oxygen reduction reaction(ORR) and oxygen evolution reaction(OER). Herein, a novel Co–doped mixed lanthanum oxide and hydroxide heterostructure(termed as Co–La MOH|OV@NC) was synthesized by pyrolysis of La–MOF–NH_(2) with spontaneous cobalt doping. Synergistic coupling of its hollow structure, doping effect and abundant oxygen vacancies creates more active sites and leads to higher electroconductivity, which contribute to the better performance. As employed as a bifunctional oxygen electrocatalyst, the resulting 3 Co–La MOH|OV@NC exhibits superior electrocatalytic activity for both ORR and OER. In assembled ZAB, it also demonstrates an excellent power density of 110.5 m W cm^(-2), high specific capacity of 810 m Ah g_(Zn)^(-1), and good stability over 100 h than those of Pt/C + RuO_(2). Density functional theory(DFT) calculation reveals that the heterointerfaces coupled with oxygen vacancies lead to an enhanced charge state and electronic structure, which may optimize the conductivity, charge transfer, and the reaction process of catalysts.This study provides a new strategy for designing highly efficient bifunctional oxygen electrocatalysts based on rare earth oxide and hydroxides heterointerface. | Jie Zhanga Jinwei Chen Yan Luo Yihan Chen Chenyang Zhang Yingjian Luo Yali Xue Honggang Liu Gang Wang Ruilin Wang | 2021 | Journal of Energy Chemistry2021，30，9： | 1 |
| 20 | Bilirubin inhibits the anticancer activity of sorafenib by blocking MCL-1 degradation in hepatocellular carcinoma cells显示文摘Objective:Sorafenib is a first-line drug for advanced hepatocellular carcinoma(HCC).Unfortunately,most patients with HCC do not respond to sorafenib,mainly because of the frequent development of drug resistance.Bilirubin is an end metabolite of heme catabolism and an indicator of liver function,but its direct role in regulating the anticancer activity of sorafenib in HCC cells is unclear.In the current study,we aimed to investigate the mechanism of action of bilirubin in sorafenib-mediated tumor suppression in HCC.Methods:A retrospective observational cohort of 100 patients receiving sorafenib was conducted to evaluate the potential role of bilirubin in predicting the prognosis of patients with HCC.Human HCC cell lines were treated with sorafenib in the absence or presence of bilirubin,and cell proliferation,apoptosis,and signaling pathways were assayed.The antagonistic effect of bilirubin toward sorafenib was assessed in nude mice bearing HCC xenografts.Results:Serum levels of bilirubin(including total,direct,and indirect bilirubin)negatively correlated with the overall survival of patients with HCC treated with sorafenib(P<0.05).Both in vitro and in vivo analyses demonstrated that bilirubin significantly abrogated sorafenib-mediated proliferation inhibition and apoptosis induction in HCC cells(P<0.05).Mechanically,bilirubin inhibited sorafenib-induced activation of GSK-3βand subsequent downstream MCL-1 degradation.Conclusions:Our study provides experimental evidence of the antagonistic effect of bilirubin toward sorafenib-mediated anticancer activity in HCC,and it suggests that bilirubin could be used to predict the efficacy of sorafenib treatment. | Leyi Yao Qian Zhao Ding Yan Ziying Lei Yali Hao Jinghong Chen Qian Xue Xiaofen Li Qingtian Huang Daolin Tang QPing Dou Xin Chen Jinbao Liu | 2022 | Cancer Biology & Medicine2022，19，7： | 0 |
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