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11篇 您的检索式:作者名="Yaling Gan"
    题名 作者 年代 出处 被引量
1Ecosystem functions, services and their values – a case study in Xingshan County of China显示文摘Zhongwei Guo Xiangming Xiao Yaling Gan Yuejun Zheng 2001Ecological Economics2001,,1:2
2Landscape planning for a rural ecosystem: case study of a resettlement area for residents from land submerged by the Three Gorges Reservoir, China显示文摘Guo Zhongwei Xiao Xiangming Gan Yaling 2003Landscape Ecology2003,18,5:1
3Ecosystem functions, services and their values – a case study in Xingshan County of China显示文摘Zhongwei Guo Xiangming Xiao Yaling Gan Yuejun Zheng 2001Ecological Economics2001,,1:1
4Landscape planning for a rural ecosystem: case study of a resettlement area for residents from land submerged by the Three Gorges Reservoir, China显示文摘Zhongwei Guo Xiangming Xiao Yaling Gan Yuejun Zheng Landscape Ecology0,,:1
5Ecosystem functions,services and their values-a case study in Xingshan County of China显示文摘GUO Zhongwei XIAO Xiangming GAN Yaling 2001Ecological Economics2001,38,1:1
6Ecosystem functions,services and their values--a case study in Xingshan County of China显示文摘Guo Zhongwei Xiao Xiangming Gan Yaling 2001Ecological economics2001,38,:1
7Ecosys- tem functions, services and their values- a case study in Xingshan County of China 显示文摘Zhongwei Guo Xiangming Xiao Yaling Gan 2001Ecological Economics2001,38,:1
8Ecosystem functions, services and their values: a ease study in Xinshang County of China显示文摘Guo Zhongwei Xiao Xiangming Gan Yaling 2001Ecological Economics2001,38,1:1
9Ecosystem functions, services and their values: a case study in Xinshang County of China显示文摘Guo Zhongwei Xiao Xiangming Gan Yaling 2001Ecological Economics2001,38,1:1
10Innovative Irinotecan-Loaded Nanomicelles Will Enter Phase I Clinical Trial in 2021显示文摘Recent progress at the National Center for Nanoscience and Technology of China has enabled an extremely facile method to encapsulate irinotecan(CPT-11)into micelle-based nanoparticles(named as IH-NM).In preclinical study,compared with free CPT-11,IH-NM exhibited 1.56-fold higher maximum tolerance dose(MTD),-2.45-fold higher antitumor efficacy at 80%of MTD dosage,higher plasma exposure,and slower clearance from the plasma.The IH-NM technology received Clinical Trial Permission from the National Medical Products Administration(NMPA)of China on Mar 6,2019.The Phase I clinical trial is under preparation.Chan Li Jing Xu Yaling Gan Xing-Jie Liang 2020The Innovation2020,1,3:0
11LAL test and RPT for endotoxin detection of CPT-11/DSPE-mPEG_(2000) nanoformulation: What if traditional methods are not applicable?显示文摘Endotoxin detection is an important step in drug characterization. Herein we found that a chemotherapeutic drug nanoformulation composed of irinotecan hydrochloride(CPT-11) and an amphiphilic molecule DSPE-mPEG_(2000) can interfere with the limulus amebocyte lysate assay(LAL). Furthermore, the rabbit pyrogen test(RPT) results indicated that at a relatively high dosage, the drug irinotecan hydrochloride can induce a hypothermia effect which may render the RPT results ambiguous in determination of the safety of the drug formulation.Our findings demonstrate limitations of endotoxin detection in micellar drugs,and call for the necessity of developing reliable endotoxin detection methods that can overcome the interference of nanomaterials in order to better ensure the drug safety of patients in future pharmaceutical drug development.Yanan Jin Juanjuan Jia Chan Li Jianqi Xue Jiabei Sun Kaiyuan Wang Yaling Gan Jing Xu Yaqin Shi Xingjie Liang 2018Asian Journal of Pharmaceutical Sciences2018,13,3:0
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