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| 1 | Epidemiological Data of Work-Related Musculoskeletal Disorders—China,2018–2020显示文摘Summary What is already known about this topic?In recent decades,work-related musculoskeletal disorders(WMSDs)have become increasingly prominent and have become an important issue that is of universal concern and an urgent need to be solved in all countries of the world.What is added by this report?The top three industries or occupational groups with the highest standardized prevalence rate of WMSDs were flight attendants,medical staff,and vegetable greenhouses in that order.Women workers were 1.5 times more likely to suffer from WMSDs than men workers. | Ning Jia Huadong Zhang Ruijie Ling Yimin Liu Gang Li Zaoliang Ren Yan Yin Hua Shao Hengdong Zhang Bing Qiu Meibian Zhang Dayu Wang Qiang Zeng Rugang Wang Jianchao Chen Danying Zhang Liangying Mei Yongquan Liu Jixiang Liu Chengyun Zhang Tianlai Li Qing Xu Ying Qu Xueyan Zhang Xin Sun Zhongxu Wang | 2021 | China CDC weekly2021，3，18： | 13 |
| 2 | Investigation on Work-Related Musculoskeletal Disorders--China, 2018−2019显示文摘What is already known about this topic?Work-related musculoskeletal disorders(WMSDs)have a high prevalence and seriously harmful,which has attracted extensive attention in various countries in the world.Currently,the occurrence and rules of WMSDs in key industries are not known in China.What is added by this report?The prevalence of WMSDs is relatively high among professional populations in key industries in China,with the most commonly affected body parts concentrated in neck,shoulders,and low back and increasing with age and working years.What are the implications for public health practice?This study determined the prevalence and distribution characteristics of WMSDs in key industries in China and provided scientific evidence to recommend for inclusion of WMSDs in the new revision of the list of occupational diseases in China. | Ning Jia Huadong Zhang Ruijie Ling Yimin Liu Gang Li Zaoliang Ren Yan Yin Hua Shao Hengdong Zhang Bing Qiu Meibian Zhang Dayu Wang Qiang Zeng Rugang Wang Jianchao Chen Danying Zhang Liangying Mei Yongquan Liu Jixiang Liu Chengyun Zhang Tianlai Li Qing Xu Ying Qu Xueyan Zhang Xin Sun Zhongxu Wang | 2020 | China CDC weekly2020，2，18： | 11 |
| 3 | Arsenic trioxide alleviates acute graft-versus-host disease by modulating macrophage polarization显示文摘This study aimed to explore macrophage polarization in acute graft-versus-host disease after hematopoietic stem cell transplantation, and investigated if arsenic trioxide(ATO) could correct this imbalance. In the colon of GVHD mice, we found that the number of F4/80+iNOS+ cells as well as the expression intensity of TNF-α and IL-1β was greater in the GVHD group than in the BM group, whereas the number of F4/80+CD206+ cells and the expression intensity of IL-10 and TGF-β was greater in the BM group than in the GVHD group. We investigated the effect of ATO on GVHD mice, and found that ATO treatment clearly improved the survival of the mice and reduced the severity of GVHD. In addition, ATO reduced the number of F4/80+iNOS+ cells, and increased the number of F4/80+CD206+ cells in the colon of GVHD mice. Furthermore, ATO sharply decreased CD86 and CD80 expression, and increased CD163 and CD206 expression in macrophages induced from aGVHD patients. Therefore,ATO can modulate the M1 and M2 phenotype in GVHD mice or in macrophages from aGVHD patients. Our data suggest that macrophage polarization is involved in the pathogenesis of aGVHD, and ATO treatment modulates macrophage polarization toward an M2 phenotype. | Xiao Liu Yan Su Xueyan Sun Haixia Fu Qiusha Huang Qi Chen Xiaodong Mo Meng Lv Yuan Kong Lanping Xu Xiaojun Huang Xiaohui Zhang | 2020 | Science China(Life Sciences)2020，63，11： | 6 |
| 4 | Gut microbiome alterations and its link to corticosteroid resistance in immune thrombocytopenia显示文摘Quantitative metagenomic studies have linked the gut microbiota to autoimmune disorders.Here,we performed deep shotgun metagenomic sequencing of fecal samples from 99 immune thrombocytopenia(ITP)patients and 52 healthy controls.Dysbiosis in the gut microbiome of ITP was detected phylogenetically and functionally,and classifier based on species markers distinguished individuals with ITP from healthy controls.In particular,the abundance of Ruminococcus gnavus,Bifidobacterium longum and Akkermansia muciniphila was markedly increased in treatment-na?ve ITP patients,and the alterations of microbial species were correlated with clinical indices.Functionally,the secondary bile acid biosynthesis and flagellar assembly were depleted in the gut microbiota of ITP,which may contribute to the onset of ITP by affecting the immune system.Furthermore,we found that corticosteroid treatment affected the gut microbiome of ITP.Compared with corticosteroid-sensitive ITP patients,we identified that the corticosteroid-resistant ITP patients displayed a distinct gut microbiome,which was different from that of the treatment-na?ve ITP patients.Together,we provided support for the critical role of gut microbiota in the development of ITP and established a foundation for further research characterizing gut microbiota in relation to corticosteroid resistance of ITP. | Yanan Wang Fengqi Liu Gaochao Zhang Yan Su Xueyan Sun Qi Chen Chencong Wang Haixia Fu Yun He Xiaolu Zhu Xiao Liu Meng Lv Xiangyu Zhao Xiaosu Zhao Yueying Li Qianfei Wang Xiaojun Huang Xiaohui Zhang | 2021 | Science China(Life Sciences)2021，64，5： | 6 |
| 5 | Large-Scale Discovery of Non-conventional Peptides in Maize and Arabidopsis through an Integrated Peptidogenomic Pipeline显示文摘Non-conventional peptides(NCPs),which include small open reading frame-encoded peptides,play critical roles in fundamental biological processes.In this study,we developed an integrated peptidogenomic pipeline using high-throughput mass spectra to probe a customized six-frame translation database and applied it to large-scale identification of NCPs in plants.A total of 1993 and 1860 NCPs were unambiguously identified in maize and Arabidopsis,respectively.These NCPs showed distinct characteristics compared with conventional peptides and were derived from introns,3′UTRs,5′UTRs,junctions,and intergenic regions.Furthermore,our results showed that translation events in unannotated transcripts occur more broadly than previously thought.In addition,we found that dozens of maize NCPs are enriched within regions associated with phenotypic variations and domestication selection,indicating that they potentially are involved in genetic regulation of complex traits and domestication in maize.Taken together,our study developed an integrated peptidogenomic pipeline for large-scale identification of NCPs in plants,which would facilitate global characterization of NCPs from other plants.The identification of large-scale NCPs in both monocot(maize)and dicot(Arabidopsis)plants indicates that a large portion of plant genome can be translated into biologically functional molecules,which has important implications for functional genomic studies. | Shunxi Wang Lei Tian Haijun Liu Xiang Li Jinghua Zhang Xueyan Chen Xingmeng Jia Xu Zheng Shubiao Wu Yanhui Chen Jianbing Yan Liuji Wu | 2020 | Molecular Plant2020，13，7： | 4 |
| 6 | Interference management in 6G space and terrestrial integrated networks: Challenges and approaches显示文摘The Space-Terrestrial Integrated Network(STIN)is considered to be a promising paradigm for realizing worldwide wireless connectivity in sixth-Generation(6G)wireless communication systems.Unfortunately,excessive interference in the STIN degrades the wireless links and leads to poor performance,which is a bottleneck that prevents its commercial deployment.In this article,the crucial features and challenges of STIN-based interference are comprehensively investigated,and some candidate solutions for Interference Management(IM)are summarized.As traditional IM techniques are designed for single-application scenarios or specific types of interference,they cannot meet the requirements of the STIN architecture.To address this issue,we propose a self-adaptation IM method that reaps the potential benefits of STIN and is applicable to both rural and urban areas.A number of open issues and potential challenges for IM are discussed,which provide insights regarding future research directions related to STIN. | Shi Yan Xueyan Cao Zile Liu Xiqing Liu | 2020 | Intelligent and Converged Networks2020，1，3： | 3 |
| 7 | Climate Characteristics of Abnormal Double-Blocking Activities over the Ural Mountains and Sea of Okhotsk显示文摘By using NCEP–NCAR daily reanalysis data for June–August of 1948–2009, the synoptic situation of the doubleblocking high pressure process over the Ural Mountains–Sea of Okhotsk region was identified objectively, and the climatic characteristics and dynamic mechanism during the double blockings were also investigated. The results suggest that the Urals–Okhotsk double-blocking high experienced obviously an abrupt change around 1977. After the change, the occurrence frequency and number of sustained days of the blocking high reduced significantly.Moreover, the zonal spacing between the Urals blocking and the Okhotsk blocking also decreased, while their meridional locations did not change much. The double blockings became strengthened in general, and the blocking high over the Sea of Okhotsk extended northward evidently. However, during the process without double-blocking activities, the intensity and location of the double-blocking high showed no noticeable variation before and after the abrupt change. In addition, dynamic diagnosis shows that after the abrupt change, the energy of the double-blocking high mainly propagated vertically from low to high levels, and transferred horizontally from low to high latitudes; whereas, previously, before the abrupt change, this occurred from high to low latitudes. Meanwhile, the development of a low pressure system was fueled between the double blockings, which meant that the double-blocking activity was beneficial to the maintenance and development of the Northeast China cold vortex. In short, diagnosis of the wave energy has provided us with a better explanation of the life cycle characteristics of this double-blocking phenomenon before and after 1977. | Gang LIU Tao WANG Xueyan YANG Yishu WANG Xu YANG Yan CUI | 2017 | Journal of Meteorological Research2017，31，4： | 3 |
| 8 | Urban biodiversity in China: Who are winners? Who are losers?显示文摘Rapid urbanization in the last three decades has impacted biogeographic patterns of wildlife in China profoundly.Large areas of natural habitats have been converted into concentrated industrial and residential areas[1].Remaining habitats in vicinities of cities are often fragmented and degraded[2].Besides land use/land cover changes,anthropogenic disturbances such as the introduction of exotic species further add pressure on local biodiversity[3].How does wildlife respond to these impacts?Who | Jun Yang Pengbo Yan Xueyan Li | 2016 | Science Bulletin2016，61，21： | 3 |
| 9 | Chemical composition of walnuts from three regions in China显示文摘To reveal the characteristic chemicals of walnuts from different origins, we analyzed fatty acid composition,tocopherols, phytosterols and total phenolic content (TPC) of walnuts from three main producing regions inChina. The results showed that walnuts were rich in polyunsaturated fatty acids, and the ratio of ω-6 to ω-3 fattyacids was close to the recommendation of Chinese Nutrition Society. Moreover, walnuts contain high contents oftocopherols (331.20–414.71 mg/kg), phytosterols (97.17–110.35 mg/100 g) and phenols (38.51–48.08 mg GAE/kg). Significant chemical differences exist among walnuts from three production regions. The highest content ofpolyunsaturated fatty acids was found in walnuts from the northern China, the highest content of tocopherols inwalnuts from southwest China, and the highest contents of phytosterol and TPC in walnuts from northwest China.However, there was no significant difference in the tocopherol, phytosterol and TPC content of walnuts betweenthe Northern China and Northwest China. The above results provide important references for manufacturers andconsumers to select suitable walnut scientifically and reasonably. | Min Liu Xueyan Wang Yu Zhang Lin Xu Yan Liu Li Yu Fei Ma Xuefang Wang Zhiyong Gong Liangxiao Zhang Peiwu Li | 2023 | Oil Crop Science2023，8，1： | 2 |
| 10 | AFLP analysis of genetic relationships and diversity of some Chinese Osmanthus fragrans cultivars显示文摘 | Yan Xueyan Xiao Baolin Han Yuanji | 2009 | Life Science Journal2009，6，2： | 1 |
| 11 | Incidence and Risk Factors of the Upper-Limb Musculoskeletal Disorders Among Occupational Groups in Key Industries—China,2018–2021显示文摘What is already known about this topic?The burden of illness and economic losses due to upper-limb work-related musculoskeletal disorders(UL-WMSDs)is high;thus,they have become a major global public health problem.At present,the epidemiological characteristics of UL-WMSDs in China's occupational population are still unknown.What is added by this report?The incidence of UL-WMSDs among key occupational groups in China is 22.5%,with distinct occupational characteristics.What are the implications for public health practice?This study has primarily determined the occurrence and potential risk factors of UL-WMSDs in key industries in China and provided data support for recommending prevention and control of the occurrence of such diseases in key industries in China,and in facilitating the addition into the China’s List of Legal Occupational Diseases. | Ning Jia Meibian Zhang Huadong Zhang Ruijie Ling Yimin Liu Gang Li Yan Yin Hua Shao Hengdong Zhang Bing Qiu Dongxia Li Dayu Wang Qiang Zeng Rugang Wang Jianchao Chen Danying Zhang Liangying Mei Xinglin Fang Yongquan Liu Jixiang Liu Chengyun Zhang Tianlai Li Jun Qi Qing Xu Ying Qu Xueyan Zhang Xin Sun Zhongxu Wang | 2022 | China CDC weekly2022，4，50： | 1 |
| 12 | Oscillation criteria of cetain delay differential equations on time scales 显示文摘 | Zhang B G Yan XinZhou Liu XueYan | | J of Difference Equations and Applications0，，： | 1 |
| 13 | Inhibition of the maize salt overly sensitive pathway by ZmSK3 and ZmSK4显示文摘Soil salinity is a worldwide problem that adversely affects plant growth and crop productivity. The salt overly sensitive (SOS) pathway is evolutionarily conserved and essential for plant salt tolerance. In this study, we reveal how the maize shaggy/glycogen synthase kinase 3-like kinases ZmSK3 and ZmSK4, orthologs of brassinosteroid insensitive 2 in Arabidopsis thaliana, regulate the maize SOS pathway. ZmSK3 and ZmSK4 interact with and phosphorylate ZmSOS2, a core member of the maize SOS pathway. The mutants defective in ZmSK3 or ZmSK4 are hyposensitive to salt stress, with higher salt-induced activity of ZmSOS2 than that in the wild type. Furthermore, the Ca^(2+) sensors ZmSOS3 and ZmSOS3-like calcium binding protein 8 (ZmSCaBP8) activate ZmSOS2 to maintain Na^(+)/K^(+) homeostasis under salt stress and may participate in the regulation of ZmSOS2 by ZmSK3 and ZmSK4. These findings discover the regulation of the maize SOS pathway and provide important gene targets for breeding salt-tolerant maize. | Jianfang Li Xueyan Zhou Yan Wang Shu Song Liang Ma Qian He Minhui Lu Kaina Zhang Yongqing Yang Qian Zhao Weiwei Jin Caifu Jiang Yan Guo | 2023 | Journal of Genetics and Genomics2023，50，12： | 1 |
| 14 | A novel long-term intravenous combined with local treatment with human amnion-derived mesenchymal stem cells for a multidisciplinary rescued uremic calciphylaxis patient and the underlying mechanism显示文摘Calciphylaxis is a rare disease characterized histologically by microvessel calcification and microthrombosis,with high mortality and no proven therapy.Here,we reported a severe uremic calciphylaxis patient with progressive skin ischemia,large areas of painful malodorous ulcers,and mummified legs.Because of the worsening symptoms and signs refractory to conventional therapies,treatment with human amnion-derived mesenchymal stem cells(hAMSCs)was approved.Preclinical release inspections of hAMSCs,efficacy,and safety assessment,including cytokine secretory ability,immunocompetence,tumorigenicity,and genetics analysis in vitro,were introduced.We further performed acute and long-term hAMSC toxicity evaluations in C57BL/6 mice and rats,abnormal immune response tests in C57BL/6 mice,and tumorigenicity tests in neonatal Balbc-nu nude mice.After the preclinical research,the patient was treated with hAMSCs by intravenous and local intramuscular injection and external supernatant application to the ulcers.When followed up to 15 months,the blood-based markers of bone and mineral metabolism improved,with skin soft tissue regeneration and a more favorable profile of peripheral blood mononuclear cells.Skin biopsy after 1-month treatment showed vascular regeneration with mature noncalcified vessels within the dermis,and 20 months later,the re-epithelialization restored the integrity of the damaged site.No infusion or local treatment-related adverse events occurred.Thus,this novel long-term intravenous combined with local treatment with hAMSCs warrants further investigation as a potential regenerative treatment for uremic calciphylaxis due to effects of inhibiting vascular calcification,stimulating angiogenesis and myogenesis,anti-inflammatory and immune modulation,multidifferentiation,re-epithelialization,and restoration of integrity. | Lianju Qin Jing Zhang Yujie Xiao Kang Liu Yugui Cui Fangyan Xu Wenkai Ren Yanggang Yuan Chunyan Jiang Song Ning Xiaoxue Ye Ming Zeng Hanyang Qian Anning Bian Fan Li Guang Yang Shaowen Tang Zhihong Zhang Juncheng Dai Jing Guo Qiang Wang Bin Sun Yifei Ge Chun Ouyang Xueqiang Xu Jing Wang Yaoyu Huang Hongqing Cui Jing Zhou Meilian Wang Zhonglan Su Yan Lu Di Wu Jingping Shi Wei Liu Li Dong Yinbing Pan Baiqiao Zhao Ying Cui Xueyan Gao Zhanhui Gao Xiang Ma Aiqin Chen Jie Wang Meng Cao Qian Cui Li Chen Feng Chen Youjia Yu Qiang Ji Zhiwei Zhang Mufeng Gu Xiaojun Zhuang Xiaolin Lv Hui Wang Yanyan Pan Ling Wang Xianrong Xu Jing Zhao Xiuqin Wang Cuiping Liu Ningxia Liang Changying Xing Jiayin Liu Ningning Wang | 2022 | Journal of Molecular Cell Biology2022，14，2： | 1 |
| 15 | Discussion on the construction technology of waterproofing roadbed on road and bridge construction显示文摘At present,with the policy support of the state in the coordinated development of the region,the modernization of the city is vigorously promoted and the level of the national urbanization is promoted rapidly and continuously.As a project of urban infrastructure construction,road and bridge plays a vital role in the construction of the whole urban road network system.Throughout the construction process of every subsystem of road and bridge,the main influence on the later period of road and bridge is waterproof pavement.The level of construction of waterproof subgrade is closely related to the construction quality and construction level of the entire project.The two are coordinated and mutually unified,and how to further improve the waterproof road surface construction technology,construction technology and construction quality,has become a major research topic for each road and bridge construction company[1].From the technical point of view,the paper actively excavates potential security hidden dangers and threats hidden in the construction of road and bridge,and makes a comprehensive analysis of some of the most prominent problems,and explores an effective way to effectively solve the problem. | Dezhi Xia Jun Zeng Yiteng Zhao Yan Shen Xueyan Guo | 2018 | Smart Construction Research2018，2，1： | 0 |
| 16 | Synthesis of Bisboronic Acids and Their Selective Recognition of Sialyl Lewis X Antigen显示文摘 | WANG Yan'en LI Xueyan CHEN Hua ZHU Mengyuan LI Xiaoliu | 2018 | Chemical Research in Chinese Universities2018，34，3： | 0 |
| 17 | Resource allocation for network profit maximization in NOMA-based F-RANs:a game-theoretic approach显示文摘Non-orthogonal multiple access(NOMA)based fog radio access networks(F-RANs)offer high spectrum efficiency,ultra-low delay,and huge network throughput,and this is made possible by edge computing and communication functions of the fog access points(F-APs).Meanwhile,caching-enabled F-APs are responsible for edge caching and delivery of a large volume of multimedia files during the caching phase,which facilitates further reduction in the transmission energy and burden.The need of the prevailing situation in industry is that in NOMA-based F-RANs,energy-efficient resource allocation,which consists of cache placement(CP)and radio resource allocation(RRA),is crucial for network performance enhancement.To this end,in this paper,we first characterize an NOMA-based F-RAN in which F-APs of caching capabilities underlaid with the radio remote heads serve user equipments via the NOMA protocol.Then,we formulate a resource allocation problem for maximizing the defined performance indicator,namely network profit,which takes caching cost,revenue,and energy efficiency into consideration.The NP-hard problem is decomposed into two sub-problems,namely the CP sub-problem and RRA sub-problem.Finally,we propose an iterative method and a Stackelberg game based method to solve them,and numerical results show that the proposed solution can significantly improve network profit compared to some existing schemes in NOMA-based F-RANs. | Xueyan CAO Shi YAN Hongming ZHANG | 2022 | Frontiers of Information Technology & Electronic Engineering2022，23，10： | 0 |
| 18 | Ultrathin oxygen-containing graphdiyne wrapping CoP for enhanced electrocatalytic hydrogen generation显示文摘Graphdiyne(GDY)is fascinating in the construction of efficient and stable catalysts,but their performance is still somewhat restricted due to GDY’s thicker layers,as well as hydrophobic and relatively chemically inert surfaces.Herein,via oxidationexfoliation-reduction strategy,the self-supported electrode material of CoP nanosheets with ultrathin oxygen-containing GDY wrapping(CoP@RGDYO)for effective HER is constructed.The wrapping of ultrathin oxygen-containing GDY promotes charge transfer,improves the surface property,and enhances the acid and alkali resistance as well as the structural stability of the catalyst.As a result,CoP@RGDYO shows enhanced activity and stability in both acidic and alkaline media.Especially,it exhibits a low overpotential of 86 mV and exceptional stability under a 14000-cycle cyclic voltammetry scanning in alkaline media.This work provides new ideas for the design of GDY hybrid materials and the preparation of high-efficiency catalysts. | Yan Lv Xueyan Wu Hao Li Hongbo Zhang Jiaxin Li Zhiyou Zhou Jixi Guo Dianzeng Jia | 2023 | Nano Research2023，16，4： | 0 |
| 19 | Research of Constructing 3D Digital River Based on ArcEngine and SketchUp显示文摘With the development of the 3D GIS and the digital basin, it is important for us to deal with the rivers from the 3D space. Compared to traditional forms of 2D GIS, the 3D GIS system brings better user experience for us. After introducing the current development status of the 3D digital river, the paper proposes a novel method for constructing 3D digital river system. It explores the methods in 3D digital river modeling by SketchUp, driving 3D scene by ArcScene and secondary developing by ArcGIS Engine. It discusses the specific issues of 3D river modeling with a river in Nanjing, and sums up a complete 3D modeling of operational process. Finally, that proves the feasibility of the method. | Xueyan Tang Yuansheng Lou Feng Ye Xiaorong Yan | 2016 | 国际计算机前沿大会会议论文集2016，，1： | 0 |
| 20 | Three Novel Mutations of APC Gene Found in a Chinese Family with Familial Adenomatous Polyposis显示文摘Objective:To identify the causative adenomatous polyposis coli(APC)gene defects associated with a pedigree of familial adenomatous polyposis(FAP).Methods:FAP was diagnosed based on clinical manifestations,family history,as well as endoscopic and pathological examinations.The blood samples of the FAP pedigree members,colonic polyp patients,and normal individuals were collected.Genomic DNA was then extracted from those samples.APC mutation analysis was conducted via direct polymerase chain reaction(PCR)sequencing.Results:Three synonymous mutations and a missense mutation were found:c.5034G>A(p.Glyl678Gly),c.5465T>A(p.Vall 822Asp),c.5880G>A(p.Prol960Pro),and c.5274T>G(p.Serl758Ser)・Among them,the homozygous mutation on APC gene c.5034G>A has been reported,while the other three mutations have not been reported in the Chinese Han population.Individuals with c.5465T>A(p.Vall822ASP)missense mutation eventually suffer from colon cancer and have poor prognosis.We found no mutation in patients with simple intestinal polyp and in normal individuals.In addition,there were homozygous and heterozygous mutations in different patients from the same family.Conclusion:Three new mutations of APC gene were firstly reported in Han population.The missense mutation of c.5465T>A(p.Vall 822Asp)may be the cause of carcinogenesis in this FAP pedigree with poor prognosis. | Shujuan Gao Min Lin Yan Jin Zhuona Wang Yunqing Zhu Guisheng Liu Xueyan Guo | 2022 | Journal of Clinical and Nursing Research2022，6，3： | 0 |
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